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Medications for Acne

Drugs associated with Acne

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Acne: An inflammatory skin condition characterized by superficial skin eruptions around hair follicles.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
doxycycline Rx D N X 427 reviews
7.0

Generic name: doxycycline systemic

Brand names:  Doryx, Monodox, Vibramycin, Acticlate, Doxy 100, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Avidoxy, Doxy 200, Mondoxyne NL, Morgidox, Ocudox, Oraxyl, Targadox, Vibra-Tabs

Drug class: tetracyclines, miscellaneous antimalarials

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
minocycline Rx D N 281 reviews
6.0

Generic name: minocycline systemic

Brand names:  Solodyn, Minocin, Cleeravue-M, Dynacin, Myrac, Ximino

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
spironolactone Off Label Rx C N X 188 reviews
8.0

Generic name: spironolactone systemic

Brand name:  Aldactone

Drug class: potassium-sparing diuretics, aldosterone receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
clindamycin Rx B N 48 reviews
7.0

Generic name: clindamycin topical

Brand names:  Cleocin T, Clindagel, Clinda-Derm, Evoclin, Clindacin ETZ, Clindacin P, Clindacin PAC, ClindaReach Pledget, Clindets

Drug class: topical acne agents, vaginal anti-infectives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
tretinoin Rx C N 255 reviews
7.0

Generic name: tretinoin topical

Brand names:  Retin-A, Retin A Micro, Atralin, Avita, Stieva-A, Stieva-A Forte, Tretin-X

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
isotretinoin Rx X N X 585 reviews
8.0

Generic name: isotretinoin systemic

Brand names:  Claravis, Amnesteem, Absorica, Myorisan, Sotret, Zenatane

Drug class: miscellaneous antineoplastics, miscellaneous uncategorized agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
tetracycline Rx D N 13 reviews
8.0

Generic name: tetracycline systemic

Brand names:  Achromycin V, Ala-Tet, Sumycin

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
benzoyl peroxide Rx/OTC C N 24 reviews
8.0

Generic name: benzoyl peroxide topical

Brand names:  Acne Treatment, BenzEFoam, Brevoxyl Creamy Wash, Pacnex, PanOxyl, Acetoxyl, Acne-10, Acne-Clear, Acnomel BP 5, Alquam-X Acne Therapy Gel, Benprox, Benzac, Benzac AC, Benzagel, Benzagel Wash, Benzashave, BenzEFoam Ultra, Benziq, Binora, BPO, BPO 3 Foaming Cloths, BPO 6 Foaming Cloths, BPO 9 Foaming Cloths, BPO Gel, BP Wash, Brevoxyl, Brevoxyl-4, Brevoxyl-8, Brevoxyl Acne Wash Kit, Clearplex, Clearskin, Clinac BPO, Delos, Desquam-X Wash, EthexDERM BPW, Fostex BPO, Fostex Wash 10%, Inova, NeoBenz Micro, NeoBenz Micro SD, NeoBenz Micro Wash Plus Pack, Neutrogena Acne Mask, Oscion, Oxy-10, Oxy Daily Wash, Peroderm 7 Wash, Persa-Gel, Riax, SE BPO, SoluCLENZ Rx, Triaz

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
cephalexin Off Label Rx B N 3 reviews
6.0

Generic name: cephalexin systemic

Brand names:  Keflex, Biocef, Panixine

Drug class: first generation cephalosporins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
erythromycin Rx B N 1 review
7.0

Generic name: erythromycin topical

Brand names:  Ery Pads, Akne-Mycin, Emcin Clear, Erygel, Erythra-Derm, Romycin, Theramycin Z

Drug class: topical acne agents, topical antibiotics

For consumers: dosage, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
benzoyl peroxide / clindamycin Rx C N 296 reviews
8.0

Generic name: benzoyl peroxide / clindamycin topical

Brand names:  Benzaclin, Duac, Acanya, Onexton, Neuac, Z-Clinz 5, Z-Clinz 10

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
sulfamethoxazole / trimethoprim Off Label Rx D N X 112 reviews
8.0

Generic name: sulfamethoxazole / trimethoprim systemic

Brand names:  Bactrim, SMZ-TMP DS, Septra, Bactrim DS, Septra DS, Co-trimoxazole, Cotrim, Sulfatrim

Drug class: miscellaneous antibiotics, sulfonamides

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

 
adapalene Rx C N 134 reviews
7.0

Generic name: adapalene topical

Brand name:  Differin

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
benzoyl peroxide / erythromycin Rx C N 20 reviews
8.0

Generic name: benzoyl peroxide / erythromycin topical

Brand names:  Benzamycin, Benzamycin Pak

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
salicylic acid Rx/OTC C N 1 review
10

Generic name: salicylic acid topical

Brand names:  Acnevir, Acnex, Acnomel Acne Mask, Akurza, Aliclen, Bioelements Active Astringent, Clear Up Prep, Compound W, DermalZone, DHS Salicylic Acid 3%, Durasal, Fostex, Hydrisalic, Let Me Clarify Gel, Occlusal-HP, Oxy Balance Deep Pore Cleanser, Oxy Face Scrub, P & S, Propa pH Acne Med Cleansing, Propa pH Acne Med Maximum Strength, Sal-Acid Plasters, Sal-Plant Gel, Salac, Salactic Film, Salacyn, Salex, Salitop, Salkera, Salvax, Scalpicin Scalp Relief, Stri-Dex, Stridex Body Focus, Stridex Maximum Strength, Thera-Sal, Tinamed Plantar, Trans-Ver-Sal

Drug class: topical acne agents, topical keratolytics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
adapalene / benzoyl peroxide Rx C N 428 reviews
7.0

Generic name: adapalene / benzoyl peroxide topical

Brand names:  Epiduo, Epiduo Forte

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

 
azelaic acid Rx B N 22 reviews
8.0

Generic name: azelaic acid topical

Brand name:  Azelex

Drug class: topical acne agents, topical anti-rosacea agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
benzoyl peroxide / sulfur Rx C N 2 reviews
10

Generic name: benzoyl peroxide / sulfur topical

Brand names:  NuOx, BPS Gel, Sulfoxyl Regular, Sulfoxyl Strong

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

 
dapsone Rx C N 138 reviews
7.0

Generic name: dapsone topical

Brand name:  Aczone

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
ethinyl estradiol / norgestimate Rx X N X 196 reviews
6.0

Generic name: ethinyl estradiol / norgestimate systemic

Brand names:  Ortho Tri-Cyclen, Tri-Sprintec, TriNessa, Tri-Previfem, Estarylla, Mono-Linyah, Tri-Estarylla, Tri-Linyah, Tri-Lo-Marzia, TriNessa Lo

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
magnesium hydroxide Off Label Rx/OTC N N 3 reviews
8.0

Generic name: magnesium hydroxide systemic

Brand names:  Milk of Magnesia, Phillips' Milk of Magnesia, Dulcolax Milk of Magnesia, Ex-Lax Milk of Magnesia

Drug class: antacids, laxatives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

Off Label: Yes

 
sulfacetamide sodium / sulfur Rx C N 20 reviews
8.0

Generic name: sulfacetamide sodium / sulfur topical

Brand names:  Prascion Cleanser, Sulfatol, Sumadan, Zencia Wash, Avar, Avar-E, Avar-E Green, Avar-E LS, Avar Cleanser, Avar LS Cleanser, BP 10-Wash, Cerisa Wash, Clarifoam EF, Clenia Emollient Cream, Garimide, Plexion, Plexion Cleansing Cloths, Plexion SCT, Plexion TS, Prascion FC Cloths, Prascion RA, Rosac, Rosaderm Cleanser, Rosanil Cleanser, Rosula, Rosula Cleanser, SE 10-5 SS, Sulfacleanse 8 / 4, Sulfatol C, Sulfatol SS, Sumaxin, Sumaxin Cleansing Pads, Sumaxin TS, Suphera, Topisulf, Virti-Sulf, Zetacet

Drug class: topical antibiotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
tazarotene Rx X N 7 reviews
9.0

Generic name: tazarotene topical

Brand names:  Tazorac, Fabior

Drug class: topical antipsoriatics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
benzoyl peroxide / hydrocortisone Rx C N 1 review
10

Generic name: benzoyl peroxide / hydrocortisone topical

Brand names:  Bencort, Vanoxide-HC

Drug class: topical acne agents

For consumers: interactions, side effects

 
benzoyl peroxide / salicylic acid Rx C N 1 review
9.0

Generic name: benzoyl peroxide / salicylic acid topical

Brand names:  Cleanse & Treat, Cleanse & Treat Plus, Inova 4 / 1, Inova 8 / 2

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
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Topics under Acne

Alternative treatments for Acne

The following products are considered to be alternative treatments or natural remedies for Acne. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Acne.

Learn more about Acne

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Synonym(s): Acne Vulgaris; Blackheads; Breakouts; Cystic acne; Pimples; Whiteheads; Zits

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