Comparing Sulfamethoxazole / Trimethoprim vs Rifaximin
Sulfamethoxazole / trimethoprim | Rifaximin |
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Sulfamethoxazole / trimethoprim | Rifaximin |
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Prescription only
Sulfamethoxazole/trimethoprim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be... View more |
Prescription only
Prescribed for Hepatic Encephalopathy, Irritable Bowel Syndrome with Diarrhea, Irritable Bowel Syndrome, Crohn's Disease, Traveler's Diarrhea, Diarrhea, Diarrhea - Chronic. rifaximin may also be used... View more |
Related suggestions Traveler's Diarrhea
Popular comparisons
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More about Sulfamethoxazole / trimethoprim | More about Rifaximin | ||||||||
Generic Status | |||||||||
No lower-cost generic available |
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Ratings & Reviews | |||||||||
Sulfamethoxazole / trimethoprim has an average rating of 4.9 out of 10 from a total of 1717 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 47% reported a negative effect. |
Rifaximin has an average rating of 6.6 out of 10 from a total of 152 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 33% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: sulfamethoxazole / trimethoprim side effects in more detail. |
See also: rifaximin side effects in more detail. |
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Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Form(s) Available | |||||||||
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N/A |
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Brand Names | |||||||||
Bactrim, Bactrim DS, Bactrim IV, Bactrim Pediatric, Bethaprim, Bethaprim Pediatric, Co-trimoxazole, Septra, Septra DS, SMZ-TMP DS, Sulfatrim Pediatric View more | Xifaxan | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
14 hours |
10.19 hours |
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CSA Schedule ** View glossary of terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 410 drugs are known to interact with sulfamethoxazole / trimethoprim:
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A total of 68 drugs are known to interact with rifaximin:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||
First Approval Date | |||||||||
July 30, 1973 |
May 25, 2004 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.