Comparing Phenytoin vs Valproate Sodium
| Phenytoin | Valproate Sodium (valproic acid) |
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| Phenytoin | Valproate Sodium (valproic acid) |
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Prescription only
Prescribed for Epilepsy, Seizures, Anxiety, Arrhythmia, Cluster-Tic Syndrome, Neurosurgery, Status Epilepticus, Seizure Prophylaxis During or Following Neurosurgery, Myotonia Congenita, Peripheral... View more |
Prescription only
Prescribed for Epilepsy, Seizure Prevention, Seizures. Valproate Sodium may also be used for purposes not listed in this medication guide. |
Related suggestions Seizures
Popular comparisons
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| More about Phenytoin | More about Valproate Sodium (valproic acid) | ||||||||
| Ratings & Reviews | |||||||||
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Phenytoin has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 15% reported a negative effect. |
Valproate Sodium has an average rating of 3.7 out of 10 from a total of 3 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 67% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Phenytoin side effects |
View all Valproate Sodium side effects |
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| Drug Class | |||||||||
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None |
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| Generic Availability | |||||||||
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Lower cost generic |
Lower cost generic approved | ||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Phenytoin prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Di-Phen, Dilantin, Phenytek, Phenytoin Sodium, Phenytoin Sodium, Extended Release |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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15 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 858 drugs are known to interact with Phenytoin:
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A total of 426 drugs are known to interact with Valproate Sodium:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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January 06, 1953 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.