Comparing Phenytoin vs Divalproex Sodium
Phenytoin | Divalproex sodium |
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Phenytoin | Divalproex sodium |
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Prescription only
Prescribed for Seizures, Epilepsy, Status Epilepticus, Cluster-Tic Syndrome, Neurosurgery, Anxiety, Seizure Prophylaxis During or Following Neurosurgery, Arrhythmia, Myotonia Congenita, Peripheral... View more |
Prescription only
Divalproex may be used for the treatment of absence or partial seizures, as a preventive treatment for migraines, and to treat mania associated with bipolar disorder. Divalproex may adversely and... View more |
Related suggestions Popular comparisons
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More about Phenytoin | More about Divalproex sodium | ||||||||||||||||
Generic Status | |||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Phenytoin has an average rating of 7.5 out of 10 from a total of 111 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 17% reported a negative effect. |
Divalproex sodium has an average rating of 6.6 out of 10 from a total of 500 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 24% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: phenytoin side effects in more detail. |
See also: divalproex sodium side effects in more detail. |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all phenytoin prices |
View all divalproex sodium prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Di-Phen, Dilantin, Phenytek, Phenytoin Sodium, Phenytoin Sodium, Extended Release | Depakote, Depakote ER, Depakote Sprinkles | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
15 hours |
16 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 833 drugs are known to interact with phenytoin:
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A total of 404 drugs are known to interact with divalproex sodium:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
January 06, 1953 |
March 10, 1983 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.