Comparing Phentermine / Topiramate vs Tirzepatide

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Phentermine / topiramate	Tirzepatide	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Phentermine / topiramate	Tirzepatide	Enter another drug to compare
Prescription only Prescribed for Weight Loss (Obesity/Overweight). Phentermine / topiramate may also be used for purposes not listed in this medication guide.	Prescription only Prescribed for Weight Loss (Obesity/Overweight), Obstructive Sleep Apnea/Hypopnea Syndrome, Type 2 Diabetes. Tirzepatide may also be used for purposes not listed in this medication guide.	Related suggestions Weight Loss (Obesity/Overweight) Phentermine Wegovy Semaglutide Mounjaro Topiramate Zepbound
More about Phentermine / topiramate	More about Tirzepatide
Ratings & Reviews
Phentermine / topiramate has an average rating of 7.7 out of 10 from a total of 692 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 13% reported a negative effect.	Tirzepatide has an average rating of 8.6 out of 10 from a total of 1904 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 5% reported a negative effect.
View all 692 reviews	View all 1904 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Dry mouth (21.0%) Tingling (12.6%) Insomnia (9.0%) Constipation (8.5%) Headaches (6.2%) Tiredness (5.5%) Dizziness (3.8%) View all Phentermine / topiramate side effects	Nausea (17.9%) Constipation (12.8%) Diarrhea (7.8%) Burping (4.5%) Vomiting (4.4%) Upset stomach (4.1%) Loss of appetite (4.1%) View all Tirzepatide side effects
Drug Class
Anorexiants	GLP-1 Agonists (Incretin Mimetics)
Generic Availability
N/A	N/A
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	N/A
Brand Names
Qsymia	Mounjaro, Zepbound
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
65 hours	120 hours
CSA Schedule ¹ View glossary of CSA terms
4 Some potential for abuse Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
X Category X Not for use in pregnancy See the full pregnancy warnings document.	Summary unavailable. See the full pregnancy warnings document.
Drug Interactions
A total of 417 drugs are known to interact with Phentermine / topiramate: 150 major drug interactions (838 brand and generic names) 264 moderate drug interactions (1138 brand and generic names) 3 minor drug interactions (13 brand and generic names)	A total of 414 drugs are known to interact with Tirzepatide: 15 major drug interactions (34 brand and generic names) 398 moderate drug interactions (2272 brand and generic names) 1 minor drug interactions (10 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Using phentermine with alcohol can increase the risk of cardiovascular side effects such as... View more	Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases... View more Talk to your doctor before using alcohol together with tirzepatide. Alcohol may affect blood... View more
Disease Interactions
Cardiovascular Glaucoma Oligohidrosis/hyperthermia Agitation Cardiac disease Glaucoma Hypertension Psychiatric disorders Pulmonary hypertension Substance abuse Suicidal tendency Renal dysfunction Metabolic acidosis Renal dysfunction Diabetics Dialysis Liver disease Angle closure glaucoma Hemodialysis Liver disease Nephrolithiasis	Thyroid cancer Acute kidney injury Pancreatitis Retinopathy Severe GI disease
First Approval Date
July 17, 2012	N/A
WADA Class View classifications
S6 - Stimulants	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Support group En español
Patient Resources
Phentermine / topiramate uses	Tirzepatide uses
Professional Resources
Monograph (AHFS) Prescribing information	Monograph (AHFS) Prescribing information
Related Treatment Guide
Weight Loss (Obesity/Overweight)	Weight Loss (Obesity/Overweight) Obstructive Sleep Apnea/Hypopnea Syndrome Type 2 Diabetes

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Phentermine / Topiramate vs Tirzepatide

See also:

Wegovy

Ozempic

Mounjaro

Rybelsus

Zepbound

Victoza

Contrave

Saxenda

Qsymia

Adipex-P

Further information

Comparing Phentermine / Topiramate vs Tirzepatide

See also:

Further information

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