Comparing Ozempic vs Wellbutrin XL
| Ozempic (semaglutide) | Wellbutrin XL (bupropion) |
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| Ozempic (semaglutide) | Wellbutrin XL (bupropion) |
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Prescription only
Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression, Seasonal Affective Disorder. Wellbutrin XL may also be used for purposes not listed in this medication guide. |
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| More about Ozempic (semaglutide) | More about Wellbutrin XL (bupropion) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ozempic has an average rating of 6.7 out of 10 from a total of 1539 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 23% reported a negative effect. |
Wellbutrin XL has an average rating of 7.5 out of 10 from a total of 493 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Ozempic side effects |
View all Wellbutrin XL side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Ozempic prices |
View all Wellbutrin XL prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other semaglutide brands include: Rybelsus, Wegovy | Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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168 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 273 drugs are known to interact with Ozempic:
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A total of 559 drugs are known to interact with Wellbutrin XL:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
August 28, 2003 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.