Comparing Macitentan vs Tadalafil
| Macitentan | Tadalafil |
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| Macitentan | Tadalafil |
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Prescription only
Prescribed for Pulmonary Arterial Hypertension. Macitentan may also be used for purposes not listed in this medication guide. |
Prescription only
Tadalafil is used to treat erectile dysfunction (ED) or to reduce symptoms of benign prostatic hyperplasia (BPH). One 'as needed' tablet lasts for 36 hours or tadalafil is available as a lower... View more |
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| More about Macitentan | More about Tadalafil | ||||||||
| Ratings & Reviews | |||||||||
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Macitentan has an average rating of 7.5 out of 10 from a total of 11 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 27% reported a negative effect. |
Tadalafil has an average rating of 8.4 out of 10 from a total of 779 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 10% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Macitentan side effects |
View all Tadalafil side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Tadalafil prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Opsumit | Adcirca, Alyq, Chewtadzy, Cialis, Tadliq | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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48 hours |
17.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 210 drugs are known to interact with Macitentan:
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A total of 341 drugs are known to interact with Tadalafil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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October 18, 2013 |
November 21, 2003 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.