Comparing Invega Sustenna vs Lybalvi
| Invega Sustenna (paliperidone) | Lybalvi (olanzapine / samidorphan) |
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| Invega Sustenna (paliperidone) | Lybalvi (olanzapine / samidorphan) |
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Prescription only
Invega Sustenna is a long-acting form of paliperidone that is injected into the deltoid or gluteal muscle once a month after an initial loading dose. It is similar in its pharmacology and action to... View more |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Lybalvi may also be used for purposes not listed in this medication guide. |
Related suggestions Schizophrenia
Popular comparisons
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| More about Invega Sustenna (paliperidone) | More about Lybalvi (olanzapine / samidorphan) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Invega Sustenna has an average rating of 3.9 out of 10 from a total of 192 ratings on Drugs.com. 27% of reviewers reported a positive effect, while 59% reported a negative effect. |
Lybalvi has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 6% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Invega Sustenna side effects |
View all Lybalvi side effects |
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| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Invega Sustenna prices |
View all Lybalvi prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other paliperidone brands include: Erzofri, Invega, Invega Hafyera, Invega Trinza |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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23 hours |
54 hours (empirically) |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 629 drugs are known to interact with Invega Sustenna:
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A total of 702 drugs are known to interact with Lybalvi:
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 31, 2009 |
May 28, 2021 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.