Comparing Dotti vs Estrace Vaginal Cream
| Dotti (estradiol) | Estrace Vaginal Cream (estradiol) |
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| Dotti (estradiol) | Estrace Vaginal Cream (estradiol) |
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Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms. Dotti may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Estrace Vaginal Cream may also be used for purposes not listed in this medication guide. |
Related suggestions Atrophic Vaginitis
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| More about Dotti (estradiol) | More about Estrace Vaginal Cream (estradiol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Dotti has an average rating of 3.2 out of 10 from a total of 44 ratings on Drugs.com. 23% of reviewers reported a positive effect, while 75% reported a negative effect. |
Estrace Vaginal Cream has an average rating of 6.6 out of 10 from a total of 82 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Dotti side effects |
View all Estrace Vaginal Cream side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Lower cost generic approved | Lower cost generic approved | ||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Dotti prices |
View all Estrace Vaginal Cream prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other estradiol brands include: Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other estradiol brands include: Estring, Imvexxy, Vagifem, Yuvafem | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 374 drugs are known to interact with Dotti:
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A total of 244 drugs are known to interact with Estrace Vaginal Cream:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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N/A |
January 31, 1984 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.