Comparing Diclofenac vs Acetaminophen / Hydrocodone
Diclofenac | Acetaminophen / hydrocodone |
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Diclofenac | Acetaminophen / hydrocodone |
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Prescription only
Diclofenac is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs. Prescribed... View more |
Prescription only
Acetaminophen/hydrocodone may be used to treat moderate-to-severe pain that is unrelieved by nonopioid analgesics. However, its use is limited by the dependence and addiction potential of the... View more |
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More about Diclofenac | More about Acetaminophen / hydrocodone | ||||||||||||||||
Generic Status | |||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Diclofenac has an average rating of 7.4 out of 10 from a total of 690 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 20% reported a negative effect. |
Acetaminophen / hydrocodone has an average rating of 6.0 out of 10 from a total of 1333 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 34% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: diclofenac side effects in more detail. |
See also: acetaminophen / hydrocodone side effects in more detail. |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all diclofenac prices |
View all acetaminophen / hydrocodone prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Cambia, Cataflam, Lofena, Voltaren, Zipsor, Zorvolex | Xodol, Zyfrel | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
1.8 hours |
3.8 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 422 drugs are known to interact with diclofenac:
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A total of 634 drugs are known to interact with acetaminophen / hydrocodone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
July 28, 1988 |
May 03, 1982 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.