Comparing Caplyta vs Pristiq
| Caplyta (lumateperone) | Pristiq (desvenlafaxine) |
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| Caplyta (lumateperone) | Pristiq (desvenlafaxine) |
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Prescription only
Caplyta is an atypical antipsychotic that is used to treat adults with schizophrenia or depression associated with bipolar disorder. Sleepiness is the most common side effect and it should not be... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression. Pristiq may also be used for purposes not listed in this medication guide. |
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| More about Caplyta (lumateperone) | More about Pristiq (desvenlafaxine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Caplyta has an average rating of 6.7 out of 10 from a total of 191 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 28% reported a negative effect. |
Pristiq has an average rating of 6.9 out of 10 from a total of 1132 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Caplyta side effects |
View all Pristiq side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Caplyta prices |
View all Pristiq prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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18 hours |
11 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 607 drugs are known to interact with Caplyta:
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A total of 483 drugs are known to interact with Pristiq:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 20, 2019 |
February 29, 2008 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.