Comparing Amantadine vs Methylphenidate
Amantadine Remove Amantadine from your drug comparison | Methylphenidate Remove Methylphenidate from your drug comparison |
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Amantadine Remove Amantadine from your drug comparison | Methylphenidate Remove Methylphenidate from your drug comparison | ||||||||||||||||
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Prescribed for Extrapyramidal Reaction, Parkinson's Disease, Influenza, Influenza A. May also be prescribed off label for Chronic Fatigue Syndrome, ADHD, Fatigue, Head Injury, Influenza Prophylaxis,... View more |
Methylphenidate improves symptoms of ADHD but carries with it a risk of dependence and side effects such as insomnia are common. Prescribed for ADHD, Narcolepsy, Depression. May also be prescribed... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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7.1
For Parkinson's Disease: Works to stop Dyskinesia caused by senement/dopamine pills |
7.3
For ADHD: It works for me but it gives side effects. I can finally focus with 52mg! Still I am impulsive but I don’t get distracted and finally I can get stuff done!!! But it took me weeks to get used to the doses until reaching 52mg, and I still have side effects sometimes (specially if I haven’t sleep good, for some reason). However I am going through a lot of stress and with the meds sometimes I get nausea, palpitations, loss of appetite and I am losing a lot of weight (I’m already very thin). I’ve been two weeks with this dose and side effects are slowly disappearing, but I’m not sure if they will go for good. At least I focus finally, and that’s what I need to finish my masters in neuroscience.. For ADHD: So far is the 3rd day of taking 10MG OF RITALIN IR. So far I feel I can finally get work done, less tapping of the feet and less fidgety, talk a lot more, can start conversations, etc. I can think before I act but sometimes I act out but not as much. But however my hands shake a little. And takes longer to 'kick in' it takes 40 mins to an hour a half. But when it 'kicks in' it lasts up to 4-5 hours. It really does help with my moderate ADHD. |
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Drug Class |
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Side Effects |
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See the full amantadine side effects document. |
Commonly reported side effects include: insomnia, nausea, headache, vomiting, decreased appetite, and xerostomia. See the full methylphenidate side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all amantadine prices |
View all methylphenidate prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Gocovri, Osmolex ER | Adhansia XR, Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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19 hours |
4 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 124 drugs are known to interact with amantadine:
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A total of 114 drugs are known to interact with methylphenidate:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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February 14, 1968 |
December 05, 1955 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Parkinson's Disease: Started Amantadine 4 weeks ago 200 mg per day. Noticed immediately occasional dizziness and diarrhea after every 100mg capsule, lost any desire to get up and do anything, Midway through the third week, I cut my dosage down to 100 mg capsule per day, taken every evening at 8 pm before bedtime and that helped me sleep better and as well increased movement in arms and right leg and foot. Happy to say I am very pleased with the results!