Skip to main content

Zoster vaccine, recombinant User Reviews & Ratings (Page 4)

Brand names: Shingrix

Zoster vaccine, recombinant has an average rating of 5.2 out of 10 from a total of 592 reviews on Drugs.com. 33% of reviewers reported a positive experience, while 38% reported a negative experience.

Reviews for Zoster vaccine, recombinant

  • fever...
  • Taken for less than 1 month
  • February 9, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Healthy woman in mid-50s. I have completed the series of both Shingrix shots. I had a very strong immune response both times. Symptoms started about 8 hours after the shot. They included chills, headache, night sweats, weird stabbing pain at different points in body and fever up to almost 102 degrees. These symptoms lasted for about 48 hours, and then I felt weak and tired for another day before being back to normal. I spent two days in bed after each shot and generally felt terrible, lying in bed moaning from discomfort. After going through all this, I better not ever get shingles..."

6 / 10
Was this helpful?YesNo
36 Report
  • DrNana
  • Taken for 1 to 6 months
  • April 12, 2019

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I had Zostavax years ago with no problem. Oct 9th '18 I had the 1st Shingrix. It was a painful injection. The next day my arm was so sore I could hardly move it. I was scheduled to attend a conference that day. I checked into the hotel and went straight to bed. I had fever, chills and body aches for the next 2 1/2 days. My arm throbbed terribly. The fever, chills and aches went away but my arm was sore for 6 weeks. I am a nurse practitioner and believe strongly in the benefits of vaccines but honestly I am afraid to get the second injection."

2 / 10
Was this helpful?YesNo
41 Report
  • MMano
  • Taken for less than 1 month
  • February 22, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Female, 56. First shingrix dose on 11/15, was having surgery on the 19th. After the vaccination, I had aches a flu-like symptoms for a day, which concerned me because of my scheduled surgery. Symptoms went away after 24 hours. Second dose was yesterday, and again I feel like I have the flu: aches, headache, fatigue. DEFINITELY get this on the day before a long weekend if you can, to let side effects abate. The pharmacist who gave me the second shot asked if I had been sick because of the first. At that point, I had forgotten the symptoms I'd had... but she said a LOT of her patients were telling her the shot made them sick. Be aware. Shingles is a horrible disease, especially as you age. My mother had it at about 76, and was in agonizing pain for weeks. This little flu-like thing is much less annoying than actual shingles."

8 / 10
Was this helpful?YesNo
35 Report
  • Mmeil
  • February 13, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis " I have the photos that show what a horrible rash that I had caused by this vaccination. I have gone to my primary physician about this. In addition to the severe pain and discomfort that I have experienced, my doctor told me that the shingles, as they were so severe, would probably leave scars. That is the least of my worries. My main concern is that I get over this burning pain that I have had consistently, for the last 38 days. It has interfered with my life. Maureen Meil"

1 / 10
Was this helpful?YesNo
35 Report
  • apopnj
  • Taken for less than 1 month
  • May 28, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Update on side effects. (I am 53 yrs old) Was administered vaccine on 5/26/2020 - Wednesday mid day feeling chills and later had mild fever - about 100.3 or so. Took a hot shower felt a little better. Before going to bed took 2 tylenol and some z quil to sleep. Today morning woke up soaking with sweat like I had been working out, fever all gone and no chills. Emailed my dr and he said the 2nd shot is a little more bothersome since you already have the antibodies in your system. It is 4:22 p,m now and feeling much better - there is still pain in the injection site and it is red but I don't care about the slight pain - all the other symptoms were a bit worrisome - lets hope to the Good Lord all goes well by tomorrow"

8 / 10
Was this helpful?YesNo
33 Report

Are you taking this medicine?

  • Not...
  • July 27, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Took first Shingrix shot and will not take the second. 65 years old. Arm was swollen, red and painful. Felt terrible. I’ve never had a reaction to a vaccine. Headache, joint pain, fever, just way off. Couldn’t sleep. That night both feet were ice cold and couldn’t get them warm. Ended up with heating pad on them both. Felt bad bad so low for about 2 days."

1 / 10
Was this helpful?YesNo
31 Report
  • Surpr...
  • November 12, 2019

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I'm an extremely healthy 59 year old. I had shingles at age 29. I got the Shingrix yesterday 9am. The nurse warned me the shot would burn going in-nope, didn't really even feel it. Went to lunch with a friend, & walking for about 90 minutes. After my hour drive home, I could barely get out of the car. Within a couple of hours, headache, severe nausea had me tossing and turning all night, muscle pain worse than any flu I've had! Even my buttocks hurt-very strange. My feet hurt so bad! Severe chills and shaking, fever 102.2 at 5:30 am. Wasn't able to take Tylenol til this morning because of nausea. This is worse than the shingles I had! I was NOT expecting any of this! Despite this, I will get the 2nd injection- shingles is more severe the older we get. I hope my symptoms don't last as long as others have said. My injection site is sore, red, hard and swollen, but I expected that, and don't consider it a big deal; just moving my arm a lot."

6 / 10
Was this helpful?YesNo
35 Report
  • AAFT
  • Taken for less than 1 month
  • February 23, 2023

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I received my first Shingrix vaccine shot in November 2022, after which I experienced muscle aches. When I received the second shot on February 18, 2023, the pharmacy tech did not provide me with any information about what to expect, except for commenting that it 'should be easier' than the first shot. However, he was very wrong. I should have done my research beforehand. I received the second shot at 3:30 pm, and by 6:30 am the next morning, I felt like I had been hit by a truck. I experienced massive and constant chills, headache, exhaustion, malaise, nausea, heartburn, diarrhea, muscle aches and pains, dizziness, vertigo, sneezing, and the upper arm that had been injected was extremely sore for five consecutive days. I even developed a small rash around the vaccine injection site. These symptoms lasted for about 48 hours. Around 24 hours later, I developed a sore throat, congestion, and the sneezing returned, along with exhaustion/malaise. Even now, five days after the second Shingrix vaccine shot, I'm still not feeling well enough to resume all of my daily activities."

2 / 10
Was this helpful?YesNo
13 Report
  • HJano
  • January 8, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I had a bad experience. First shot was painful and I didn't feel great - but that was the easy part. The day after the 2nd dose I became very ill, fever of 102, nausea, body aches, horrible headache. That was followed by sharp stabbing pains, pins and needles, itching, sciatic pain and nerve zaps throughout my body. A week later a rash appeared on my lower back. Went to urgent care where I was diagnosed with Post Herpetic Neuralgia. The bottoms of my feet became very painful - nerve pain, not muscle pain. Many doctor visits later - no one wants to admit the shot was the culprit. It definitely was. Finally a few months later the foot and nerve pains are subsiding. Starting to feel normal again. One doctor surmised that I had an autoimmune reaction to the shot. Beware if you have any autoimmune disorders."

1 / 10
Was this helpful?YesNo
32 Report
  • KMaw
  • Taken for less than 1 month
  • March 27, 2021

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Had my first dose yesterday, 3/26/21. My provider said nothing to me about how horrible I would feel within hours. I specifically asked questions regarding side effects and was told "There may be some pain at the injection site." I really hope this exhaustion, pain in my shoulder, lack of appetite and dizziness go away. Why not be honest with their patients?"

10 / 10
Was this helpful?YesNo
25 Report
  • Honey...
  • Taken for less than 1 month
  • January 23, 2021

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I’m a healthy active 69 year old female who eats well & walk or lift weights. I got the shingles injection (second dose). I’m miserable, ache all over, shivering, feel like bad flu. I have had Covid 19, in early October, so we know it’s not that. I just guess I’ll have to ride it out."

8 / 10
Was this helpful?YesNo
26 Report
  • Boo
  • February 11, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I got the first dose in June 2019. I was in so much pain that I could not walk or sleep for 24 hours. No joke. It felt like the worst nerve pain ever. Did not get the second dose. In Oct. 2019, I developed strange rashes on my arms, chest and neck after eating. It’s Feb. 2020 and my immune system is still out of whack and I have daily rashes. Hubby believes this vaccine caused all of my rashy, skin problems. I hope it goes away soon. Best wishes!"

2 / 10
Was this helpful?YesNo
31 Report
  • Ra_54
  • Taken for less than 1 month
  • May 4, 2023

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I’m 35, and I have rheumatoid arthritis. The doctor recommended I get a vaccine before starting a new biologic. I’ve had shingles twice in the past. Only adverse reactions to the pertussis vaccine as a kid. Received shingrx on 4/17/23. 12 hours later woke with a high fever, felt delirious, and was on the verge of fainting for three hours. Took ibuprofen and Tylenol which eventually broke the fever. High pulse 147. Then the throat tightness and itching began. Went to urgent care two days in a row, diagnosed with an adverse immune reaction. Placed on prednisone taper after the second visit, the doctor noted throat irritation and both of my arms swelled with a rash. Extremely fatigued, no appetite high pulse. Throat tightness persisted with itching. Extremely anxiety provoking. As a result, it’s been two weeks since the vaccine, and throat episodes clearing slowly with less frequency and intensity with each passing. Prescribed Epipen in case. Living off antihistamines still."

1 / 10
Was this helpful?YesNo
11 Report
  • guinea...
  • Taken for less than 1 month
  • August 17, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I was at the docs office for internal bleeding and they popped up giving me the shingles vaccine out of the blue. My father had shingles and it was very painful for him so I said ok without research. I've never had a reaction to a vaccine. It left the shot area very painful for days. It s been 3 weeks now and I'm still having problems with my left arm becoming very painful out of the blue and fatigue out of the blue. I'm wondering how long this will last and I'm not sure I will take the second shot. Beware!"

2 / 10
Was this helpful?YesNo
28 Report
  • MBano
  • Taken for less than 1 month
  • July 25, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "56 year old female and relatively healthy other than HBP (high blood pressure). Received first Shingrix shot yesterday 7/23/20. Low grade fever started this afternoon (12 hours later) 99.5-99.8. Arm is sore but not terribly so. I feel sluggish but not overly fatigued. The sudden fever gave me pause because of Covid but then I remembered the side effects listed for the vaccine. Hopefully this will pass in a day or so. I had shingles when I was 48 and I do not want to experience that again - complete misery for 3 weeks."

6 / 10
Was this helpful?YesNo
28 Report
  • jah
  • Taken for less than 1 month
  • February 25, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Had my first shingrix shot on 2/5/2020. Experienced a very sore arm for over three days. Felt like I had the flu. It has not been three weeks and I still have pain in my arm when I lift it level or over my shoulder where the injection was. I also have swollen neck glands and feel extremely exhausted. Going for a full blood workup but am wondering if anyone else has had this type of reaction."

Was this helpful?YesNo
30 Report
  • Red
  • August 23, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "54 year old woman, within hours after my first dose of shingrix vaccine my arm was pretty sore, then that evening I was having to apply ice packs directly on both my feet cause of the severe burning and stabbing shooting pain in both feet and my feet were red from were they felt like on fire. I have neuropathy in my feet from being type 2 diabetic but never felt such intense burning and sharp pains like I did starting that evening, next day after a night of discomfort, extreme fatigue kicked in, and all over body pain with headache, day 3 and I've begun a fever and still extremely exhausted with headache and all over body pain my blood sugar is up in the 170s which is high for me. I've tried even my prescription pain medication for relief with no results, I go for 2nd dose in 2 months. They say side effects last about 3 days, I hope I feel better soon. It's a battle between needing sleep from extreme exhaustion ."

4 / 10
Was this helpful?YesNo
27 Report
  • Mark
  • Taken for 1 to 6 months
  • November 21, 2019

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Six days after the 2nd shot my right and my knee swelled and I couldn't walk on it. Then 10 days later my left knee did the same thing happened. It has been a year since this all started and no one can tell me what's happened. All tests come back normal yet I still have no strength or stability walking. I was out of work for the last year. I never had any knee issues before the Shringrix shot. Trying to find others with severe reactions like mine"

2 / 10
Was this helpful?YesNo
31 Report
  • Nana
  • October 21, 2019

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Female, 65, mild case of MS. After first dose in June had 3 days of flu symptoms, fatigue, nausea, muscle pain. Tylenol, sleep, soak in bath salts, stretching helped, ate lightly and fell into deep sleeps. Mid Oct reluctantly went for second shot, figuring shingles prevention for rest of my life was worth it. An older sister had bad case a few years ago - something to avoid! Scheduled my life this time for 3 days to recover. Side effects this time only half as bad. Worth it to me. This site attracts worst stories. My pharmacist said most of her people reported 1-3 days feeling bad, like me. Manageable. Some had very little reaction. None extreme or longer than 3 days. For second shot I went in late afternoon for early bedtime. Had swimming workout beforehand, light lunch, felt good with body charged up. Perhaps that helped. Stayed on Tylenol, drank coca cola, green tea, had much less nausea. Slept deeply. Discomfort worth it for protection from much much worse, I think. Good luck!"

8 / 10
Was this helpful?YesNo
31 Report
  • Boomer
  • Taken for less than 1 month
  • December 9, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "This Shingrix vaccine is horrendous. I just received my 2nd dose and within 6 hours or so I was breaking out in a fever sweat with a terrible headache and Nassau. Every joint in my body aches so bad I have difficulty even walking. I put off having the 2nd shot after having a similar reaction from the first one. I'm sorry I did , because the 2nd shot has been far worse for me. Terrible vaccine! I'm not a fan of big civil lawsuits normally, but they need to be sued."

1 / 10
Was this helpful?YesNo
25 Report
  • Georgia...
  • Taken for 6 months to 1 year
  • October 24, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Shot is painful. Next day arm is about useless. Swollen, red, hot, and HURTS. I have seen people with Shingles and this pain is minor comparatively. I hate shots but this is the worst shot I have had!"

10 / 10
Was this helpful?YesNo
25 Report
  • Fraid...
  • February 28, 2020

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I had the first vaccine on August 28/20. It was horrible. My arm ached. I had flu like symptoms that lasted about 5 days. I was just miserable. I just had the 2nd vaccine on Feb 25/20 (6 months later). What a major difference. My arm still hurts which I'm sure is from a needle being put in the muscle of my upper arm. This time I had no flu symptoms and I haven't felt too bad at all. I was a tiny bit off yesterday but nothing like the first time. I have a headache today, but Advil has helped with that. I was afraid to do the second one but it's been great. I know it beats risking the alternative. You can't expect the same reaction as the first time as you just don't know. I'm happy my stress was for nothing."

10 / 10
Was this helpful?YesNo
28 Report
  • Silvia
  • January 28, 2021

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I’m an active 70-year old healthy female with no medical conditions. Had shingles 25 years ago, so decided to get the new vaccine. My first injection in this second round was no problem at all. Got my second injection yesterday morning. In the afternoon and evening, I felt achy and chilled. Last night I slept as if I‘d been hit by a truck and couldn’t move. My body was a dead weight. This morning I felt better and got up to make coffee. But when I got downstairs, I felt clammy and thought I was going to pass out. A wave of nausea hit me like a ton of bricks, and I had to lie down on the floor. I stretched out on the floor for a few minutes and then crawled to the bathroom with an urgency to sit on the toilet. Then dry heaves released everything that was in my stomach onto the floor, which thankfully wasn’t much. Then it seemed to pass. After reading others’ experiences, hoping to fast forward the rest of this day and the next one."

Was this helpful?YesNo
23 Report
  • Billy
  • Taken for less than 1 month
  • January 1, 2023

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "Don’t get the vaccine, I have had 3 cases of shingles with long-term nerve damage. But have never gone thru the living hell that 2nd vaccination put me thru. Had horrible COVID, had my orbital bone shattered, swine flu, you name it, that vaccine and its side effects hit me around 9 pm, received it at 3. I was so fatigued I couldn’t even get up to pee. The next day and I’m 72 hours out, I roll around in my bed In excruciating pain in every joint in my body. My head feels like I’m about to stroke out. It hurts so bad, my stomach hurts so much I don’t know if I want to vomit or sit on the toilet. I’m in a daze, in too much pain to even talk to anyone. I would rather have shingles again! Don’t take this stuff. 72 hours and still the same, even my hands are in pain, I can’t pick anything up!!!!"

7 / 10
Was this helpful?YesNo
12 Report
  • Anonymous
  • Taken for less than 1 month
  • June 12, 2023

Shingrix (zoster vaccine, recombinant) for Herpes Zoster, Prophylaxis "I got the shingles vaccine, on June 8. The next morning, I woke up with sharp pain in my throat as if I was having a throat viral infection. Later that day, on Friday, I started to get chills and a fever of 102.6. I took Tylenol 650mg, and it kept my fever down to 100, but it did not go lower than this. After 6 hours, the temperature raised again. So, that is how it is going all these days in a circle: 102.6F- Tylenol 650 - 100F, and then all over again. I thought, maybe on the fourth day after the injection it will be better - but it is not. My throat is killing me, I have a runny nose, a pounding headache, weakness, nausea, and fever. I have never had anything like this. I am going to contact my doctor to get help, but I am terrified reading the previous reviews. Nobody informed me that these types of things could happen. I cannot judge the effectiveness of the vaccine, but I am not going to take the second injection."

Was this helpful?YesNo
9 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.