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Effexor XR User Reviews & Ratings (Page 2)

Effexor XR has an average rating of 6.7 out of 10 from a total of 922 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 24% reported a negative experience.

Reviews for Effexor XR

  • 1204
  • Taken for less than 1 month
  • August 9, 2020

For Major Depressive Disorder "I have major depression, an eating disorder and anxiety. I have struggled for years on and off multiple anti depressants. I just started Effexor 2.5 weeks ago. Already I am so shocked at the absolute change. I wake up happy. I regained interest in things. I no longer have thoughts of suicide and am not crying every day. I honestly feel like it has given me my life back."

10 / 10
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149 Report
  • indig...
  • Taken for 6 months to 1 year
  • July 5, 2017

For Generalized Anxiety Disorder "Before I was to start this medication I searched and thought I better not take this medication because of all the people who said it was very bad. I have been on Celexa since 2000 with ativan 3 mg per day if needed. I had to get off of Celexa because I started having panic attacks and wasn't working for me. It didn't really work that great for for the past six years. I was terrified to take Effexor XR. Well I couldn't live with panic and anxiety anymore so I took it. I focus better, I don't dwell on things. I can sit and watch a movie without my mind wondering or worrying. I have lost 15 lbs. My husband notices a difference being more outgoing. Don't listen to what has been written. I wish I started this a long time ago. Best of Luck"

10 / 10
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232 Report
  • THISC...
  • July 27, 2017

For Anxiety "First off, I want to say I never take the time to write reviews however I do end up myself reading everyone else's so I hope this helps someone! I'm 22 Female, and for about 4 years suffered from anxiety. First it started off as panic anxiety then with failure of trying medications Prozac, Zoloft, and lexapro, my head was just so much worse. I could feel the chemical imbalance I began getting daily depression and anxiety to the point I'd worry 24/7. It ruined relationships & made me seem crazy. I finally got on Effexor last month. CHANGED MY LIFE. I feel NORMAL again. Happy, no anxiety, energetic. Only side effects were yawning, vivid dreams, & at first jaw pain. I highly suggest this with panic/daily anxiety/depression mix! My fears are gone"

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Frequently asked questions

  • Anony...
  • Taken for 2 to 5 years
  • January 7, 2022

For Major Depressive Disorder "I was in the deepest, darkest valley of suicidal ideation. I had it all in life and one day, I stopped sleeping, eating, smiling, and functioning. I was miserable. I was scared. I was paralyzed by depression and anxiety. Imagine having an 8-hour panic attack but having such deep depression that you couldn’t move off the couch. I literally just sat and watched the sun come up and go down. Day after day, night after night. After a while, I lost the ability to cry. I thought death was the only solution so I thought about it all the time. Luckily, I gave the doctor a try first and after trying two other medications, we finally tried this one and it completely turned it around for me. Game changer. I started sleeping a little bit longer, eating a few more nibbles, cracking a smile here and there. Started to hear music again. Started to feel like life mattered again. Venlafaxine saved my life. Two years in and I am better than ever. Don’t be afraid! This might be the one for you too!"

10 / 10
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98 Report
  • Happy...
  • Taken for 10 years or more
  • March 10, 2014

For Anxiety "I have been on Effexor for the past 10 years - I started having panic attacks as a child although I didn't know at the time what was going on - when I was 17 the doctor prescribed Valium that I took periodically when my anxiety got really bad - finally when I was 40 the doctor suggested I go on a very low dosage of Effexor (37.5mg) because he was sure I had generalized anxiety disorder - what a difference this has made in my life - felt"weird" the first few weeks but now I have very little anxiety and really no side effects except maybe lower libido. I had no idea how much anxiety I had been living with all my life."

9 / 10
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271 Report

Are you taking this medicine?

  • Grate...
  • Taken for 5 to 10 years
  • February 4, 2020

For Depression "Everyone's different, for me this one's a LIFE SAVER! My depression began 15yrs ago. In 2014 I hit my lowest point. Previous dr had me on several meds that didn't mix well together. That whole year is a blur, I don't remember any of it except for the few grand mal seizures they caused. Eventually attempted suicide with one of the meds and ended up in a mental hospital twice within a month. My new psychiatrist took me off everything and started me on this, topped out at 150mg (which I am to this day, 6yrs later, still taking). I can't thank that psychiatrist and this miracle drug enough. Taking with Bupropion (Wellbutrin) and I'm not sure which one, but I believe one of them has got rid of my sex drive. I prefer no sex drive over that really dark place I was in. Also, if I miss taking them a couple of days in a row (again, not sure which one is causing it) I experience extreme vertigo.. not fun. Other than that, I have no other complaints just absolute gratefulness. LOVE IT!"

10 / 10
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137 Report
  • cricket
  • Taken for 1 to 6 months
  • October 1, 2021

For Panic Disorder "I have had panic attacks for many years along with agoraphobia. In August the attacks were unbearable and my NP put me on Sertraline. I was so ill and after three weeks said I would not take it anymore. He then put me on Effexor which I was really uneasy taking because of the side effects I had read about. Well I am here to say it has been a miracle drug for me. I had no side effects starting it and noticed a major improvement the second week. Now I am almost a month in and no panic attacks or anxiety at all! This is major for me. Now I am working on getting out more and driving. Please if you have major panic then this medication may be for you. Please Please give it a try. I am so very happy I did."

10 / 10
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90 Report
  • saddled
  • January 17, 2013

For Generalized Anxiety Disorder "Effexor XR changed my life. With Effexor, the anxiety is gone and I am able to stay calm in any situation and sleep well every night. My doctor has told me I can NEVER get off this medication because it changes something in the brain having to do with serotonin. No hope of functioning without this in my system. Well, I can live with that. I've got my life back."

9 / 10
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264 Report
  • Anon
  • Taken for 6 months to 1 year
  • December 18, 2023

For Anxiety "I was on sertraline for about 6 months and although it worked great for me at first, the positive effects quickly died off and with every increase, I felt more and more disconnected from reality. I researched and found Effexor had worked for a lot of people when SSRIs hadn't. My GP also agreed it was a great choice. Despite this, I let the horror stories get to me and it took me 2 months to make the jump, but I haven't looked back since. I haven't had a single negative side effect and feel practically 100% back to myself pre-anxiety. It's been 6 months on 75mg and I am truly so grateful I gave this medication a shot. Hopefully, this helps someone that is in the same position as I was."

10 / 10
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20 Report
  • Jon...
  • Taken for 1 to 6 months
  • September 6, 2016

For Anxiety "I told myself I'd come back and write a review if I liked Effexor, because people tend to only write reviews if they don't like it, and that's scary for someone who is trying to figure out whether to try it or not. This was the first medication I've tried to treat my chronic GAD. Before Effexor, I was living in a state of constant panic and anxiety. It was really awful, and I felt like I couldn't continue much longer without completely breaking down. I'm now 3 months in, and it has helped so much. I am still myself and I have anxious thoughts, but there is no longer that sense of panic and overwhelming fear. I feel like I did pre-anxiety and its wonderful. Everyone reacts differently, but have hope! Medication can work!"

9 / 10
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191 Report
  • STEEL
  • Taken for 1 to 6 months
  • April 17, 2019

For Anxiety "I owe a great thank you to Effexor. My cons are vivid dreaming and minor sleep difficulties. But the pros for myself, outweigh the bad. For the first time in 10+ years my anxious thoughts and sweats are almost nonexistent. I enjoy the taste of food again. And I feel like I have more purpose, I don’t walk around with the “I’m just here, useless” cloud over me. I will continue to fight to feel right, Effexor has definitely gave me my footing."

9 / 10
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139 Report
  • Spouse...
  • Taken for 2 to 5 years
  • August 4, 2021

For Depression "Please never allow anyone you love to take this drug! Effexor XR has been the worst experience for my husband the past 4 years! He has gone through so many changes, mentally he doesn’t know what is real anymore. What I mean is life, love, emotions, etc. Our marriage was the ideal marriage before he started taken it, but now it has crumbled! He has been to a mental facility twice on this drug, gone through so many personally changes, it’s unreal! Please do your research before taking this because coming off of it is a living nightmare! I know 2 people who committed suicide on this drug and Thank God I have not lost my husband on it!"

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  • 0521j...
  • January 26, 2015

For Anxiety "I have been on Effexor XR for about a year, after switching from Paxil. It is a scary thing to read all these reviews, and question about whether you should or should not take it. I personally started for anxiety, and it has helped tremendously. To me having panic attacks is not a fun task, yes are there side effects but everything you put into your body does. Please try what your doctor recommends before you read all the reviews."

10 / 10
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211 Report
  • NLDIS
  • Taken for 6 months to 1 year
  • May 2, 2014

For Depression "I've tried many different SSRI's for depression (Zoloft, Wellbutrin, Prozac) and nothing worked. I was apprehensive to take the Effexor because of online reviews but I'm so glad I did! The only side effect I've had is tiredness the first few weeks but that has since subsided. I not only feel more energy but I actually can feel happiness. On the other medicines I just felt a numbness and lack of emotion but Effexor has made me feel like me again! This has been my miracle after years of mild-severe depression."

10 / 10
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223 Report
  • Sonjatx
  • Taken for 1 to 6 months
  • May 1, 2015

For Anxiety "I have had anxiety and depression for years. Was on all different types of medicines. Even got so badly depressed and anxious that I was bedridden for almost 1 year. I got switched to Effexor and in a few days felt great! I cannot believe I spent all these years in darkness! This is the best medicine ever for me! I am not depressed and zero anxiety! I just wish I would have been on it earlier."

10 / 10
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206 Report
  • Downout
  • Taken for less than 1 month
  • August 8, 2014

For Anxiety "I have suffered with major depression my whole adult life. Have been on several types of antidepressants all of which left me feeling like a zombie. The first time I took Effexor I noticed a major swing in my moods it has been a total saviour for me. Two weeks ago I was in bad shape, today a week of Effexor I feel on top of the world . This medication with the help of family friends and councilor had without a doubt totally turned my life around now everything in my life is happy and positive. Without this medication my future would've been bleak to say the least."

10 / 10
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216 Report
  • ATTOR...
  • Taken for 1 to 6 months
  • July 29, 2019

For Anxiety "I have been on Effexor for just over a month and I can say that I'm rather surprised. I am a 25 year old male, who has been on antidepressants for almost 12 years (unfortunately I was diagnosed with depression and a social anxiety disorder at a very young age). Prior to being prescribed Effexor - I was on zoloft for a few years. Zoloft worked, but as time went on, started to loose it's effectiveness. With Effexor I have more energy and feel that I can get through the day. I hope this medicine continues to work for anyone suffering <3"

8 / 10
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126 Report
  • momof...
  • August 22, 2017

For Anxiety "I started Effexor XR (generic version) about 3 weeks ago. I will admit, the bottle sat on my counter for a week before I took my first one, because the negative reviews terrified me. I finally took one and I am so glad I did! I have been on practically every anxiety/ depression med there is and had kind of lost hope with them working. I have also tried several different natural methods and they helped a little bit, but not nearly enough. I struggle mainly with anxiety and have for about 15 years now. By day 3, I had already noticed a difference. It's been 3 weeks & not only is my anxiety significantly better, I no longer have swollen joints or numbness in my hands & feet, I'm so much happier & way less stressed. Life changing!!"

10 / 10
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160 Report
  • Cmano
  • Taken for 1 to 6 months
  • August 16, 2019

For Depression "After 15 years of struggling with deep depression, pmdd, and post partum depression, 1 suicide attempt and 1 hospitalization, I have found the medicine Effexor that has worked for me. It's been a long road but now I'm at peace and living life to the fullest."

9 / 10
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122 Report
  • SSKirby
  • Taken for 1 to 6 months
  • March 13, 2014

For Anxiety "I have been on Effexor XR 75mg for two months now, after previously being on Zoloft and Celexa. The two other medications were not effective for my anxiety and depression, and they tended to make me either tired or foggy regardless of the time of day that I took them. I expected the tiredness to wear off, but the foggy feeling never did. My doctor prescribed Effexor XR, and it has been very effective for both my depression and anxiety symptoms. I am not 100% perfect, and I still have anxiety, but in the appropriate moments. The moments of unreasonable anxiety attacks are fewer and far between since starting the medicine. I had no negative side effects, and I take it every morning at 9am."

9 / 10
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213 Report
  • Stixie...
  • October 14, 2016

For Anxiety "I cannot describe how life changing this medication has been for me. I've been suffering from anxiety/depression, specifically social anxiety and low self esteem, my whole life. It was at a point where I thought it was normal to be negative, pessimistic, anxious and depressed all the time. I tried EVERYTHING including therapy, exercise, diet and an array of medicines and nothing worked. I nearly developed an addiction to Xanax just trying to combat the anxiety. Prozac, lexapro, Concerta, stratera; Nothing worked. Finally got introduced to Effexor XR. Started on 75mg for 2 months, I wasn't that satisfied. I got put on 150mg for 2 months then. CANNOT BELIEVE THE DIFFERENCE. I'm happy, confident and positive. AMAZING. Long may it last."

10 / 10
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168 Report
  • Anonymous
  • May 10, 2008

For Social Anxiety Disorder "I take 300 mg of time released effexor, a day and it has changed my life 100% It has helped me to not worry about rejection if things don't go right and to give a speach in front of a audiance had always been frightning as well as any crowds with others. Or being preccupied with possible rejection every minute. I did not relize how much joy of life i was misssing,"

10 / 10
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293 Report
  • Atexun
  • May 7, 2015

For Anxiety "Started on 37.5mg for a month. First two days were only side effects - I was a little jumpy, couldn't keep legs still, and had insomnia. That went away in 48 hours. Then it shifted to making me sleepy and fairly relaxed. However, I still had breakthrough anxiety crying and didn't feel much change in depression. Decided to up the dose and have been at 75mg for a while now. No side effects. This dose has obliterated my anxiety and helped with depression. All I feel is calm and relaxed. I am more outgoing and happy. Only thing I noticed, like so many others, is that it is tough to miss a dose. But, don't let that dissuade you from trying it. It really has been a miracle for me."

10 / 10
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187 Report
  • Pisces
  • Taken for 1 to 6 months
  • March 19, 2013

For Anxiety "Effexor Saved Me After Many Failed Medicines. Current Med Combo- Effexor 75 mg, Lamictal 200 mg, Abilify 5 mg It saved me from wasting anymore time locked up in my house 24/7 and avoiding conversations, knocks at the door, people, telephone calls, and anything else involving socializing. I FINALLY LEAVE MY HOUSE. WILLINGLY and REGULARLY. Daily. I NO LONGER FEAR APPLYING FOR JOBS. I NO LONGER FEAR THE POSSIBILITY OF HAVING A JOB because I would have to deal with people. I am willing and eager to go out with friends, family, acquaintances, meet new people. SIDE EFFECTS- Only Nightmares, which eventually become less and less and then go away after 2 months. Maybe a little unpleasant at first. Definitely bearable. It's not bad for everyone."

10 / 10
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  • stars...
  • Taken for less than 1 month
  • August 27, 2014

For Anxiety "I've suffered severe anxiety/panic attacks my entire life. I've had Xanax, Valium, Prozac and Edronax over the cause of my years. I finally changed doctor, came off everything, to start where I'm at now. I began on 37.5mg over two weeks ago and noticed a difference straight away. Now on 75mg and getting better every single day. My panic attacks could cause me to pass out, so this is a huge leap in health for me. For those concerned about coming off Xanax, it's so worth the effort. I now feel like I'm getting my life back and I'm truly grateful."

9 / 10
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194 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.