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Nucynta ER User Reviews & Ratings (Page 2)

Nucynta ER has an average rating of 7.2 out of 10 from a total of 81 reviews on Drugs.com. 68% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Nucynta ER

  • Disab...
  • Taken for less than 1 month
  • December 10, 2019

For Pain "Just filled my first Nucynta 50mg X2! Have had experience with Opana , Oxycodone, Morphine and many more opiate type meds. I have CIPD with diabetic Neuropathy as well as chronic pain ! I initially am feeling some areas of pain go away! I’m going to wait longer to share updates , but am optimistic !"

9 / 10
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27 Report
  • debbieR
  • January 31, 2014

For Pain "I just started Nucynta ER I took the first dose at bedtime could not sleep the entire night, had some upset stomach, that's the bad side, I have 3 damaged disc in my neck and 3 damaged disc in my lower back, so I have a great amount of pain but from the first dose pain didn't stop completely but was greatly improved I don't know if this medication helps with anxiety but it gave me a sense of calm, didn't sleep but felt very relaxed, my cost after insurance and a coupon was only 25.00."

6 / 10
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51 Report
  • Keith...
  • August 25, 2016

For Pain "Works well to control my pain. I have been on fentanyl for 8 years. Converting to this drug has many good results. There are however many side effects but I hope to control some by tolerance until drug is completely in system"

8 / 10
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41 Report

Frequently asked questions

  • Ace
  • August 13, 2016

For Pain "Saw pain Doc went over all my test, MRI results and did an exam. Should have known he was a Nucynta ER pusher by all the posters in the office. Started me off at 150 mg x2 a day , and in the beginning it seem to work alone with Dilaudid fir BT pain. Saw the Doc 2 days before surgery and 3 months on Nucynta ER I told him it wasn't really working for me he said well let's UP your dose to 200 mg 2x a day. I had surgery no issues. Until I started back on the Nucynta ER. I had hallucinations, loss of memory and violent rage. I don't remember the last two days I was taking the medication. I ended up in the ER 3 days after spine surgery cause I went into a fit of rage. Pain Doc was called he said it was the Nucynta and to stop taking it. Bad drug"

4 / 10
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41 Report
  • PES
  • Taken for 1 to 6 months
  • August 7, 2018

For Pain "I have had multiple different surgeries, and live with chronic pain. I've been taking three Percocet 5-325 MG per day. The pain control, would only last for around 3-5 hours. The constipation that comes along with the above med, were unreal. I then ended up forming stage three hemorrhoids, and had to have a Hemorrhoidectomy, which was the worst! The pain medicine also made my depression worse, which I did not need! My pain clinic doctor, recommend Nucynta ER 50 MG, every twelve hours. There were two benefits, in taking Nucynta ER 50 MG: first, it was around the clock, pain control; and secondly, it eliminated my hard stool, and constipation. It was increased to 100 MG because of my pain levels. I was still dealing with breakthrough pain, and was given Oxycodone 5 MG, but once again, it caused more depression, and constipation, immediately! I’m going to have to stop taking the oxycodone, and talk to my pain clinic doctor about increasing my dosage of nucynta to 150 MG x 2 per day."

10 / 10
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32 Report

Are you taking this medicine?

  • mmrgreg
  • June 5, 2015

For Pain "Was taking 30 - 40 my hydrocodone, and 300 my tramadol a day for lumbar for a min all stenosis, I have 4 herniated disks so to L2. The hydrocodone was just scratching the surface of my pain. My doctor put me on 100 my Nucynta ER X2 a day and it has been so mutch better. Had to stop the tramadol. Still taking the hydrocodone, need to adjust the dose but it has bee much better, almost no side affects. They do only seem to last for 8 Jr so I will talk to my doc about doing 150 my x3 a day."

8 / 10
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42 Report
  • TinyV...
  • Taken for 2 to 5 years
  • February 21, 2018

For Pain "Nucynta is a miracle drug for me. I have a condition that caused defects in almost every vertebrae, rib and more. I’ve been in severe pain all my life and tried almost every pain med on the market with little relief and horrible side effects. I’ve been on Nucynta for five years and nothing else comes close in terms of pain relief. Before Nucynta, I was in bed almost 24/7 and required help dressing, washing etc. Now I can do my own care, and I can go out on good days. The only side effects for me are increased heart rate and short term memory issues when the IR medication “peaks.” I have no GI issues, and I am alert and clearheaded. My dose is 150mg ER 2x a day, and 100mg IR 3x a day and it hasn’t changed in 3 years. I don’t build a tolerance like I did with other opioids. When I first started I got serotonin syndrome, so they took me off of all other seratonin drugs. I haven’t had any issues since, but it is a dangerous reaction so people should know the symptoms."

10 / 10
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32 Report
  • Mnstr...
  • Taken for 2 to 5 years
  • November 1, 2017

For Pain "Have been taking Nucynta ER for nearly four years. Have degenerative disc disease and the remnants of 7 torn discs in mid-thoracic to lumbar and a cervical bulging disc. Have an old compression fracture in thoracic all caused by a 2009 accident, the torn discs are now practically non-existent and near bone to bone at several levels. Nucynta has changed my life. After taking Norcos and Roxy and others, do to no insurance at beginning, landed on Methadone as it was affordable. 3 years with Nucynta now, using nothing for breakthrough, would rather deal with little pain than be on more than have to. Can think, am back to work and providing for my family! It doesn’t fix everything, but has literally changed my life!"

8 / 10
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33 Report
  • Spanky...
  • Taken for 2 to 5 years
  • April 27, 2016

For Pain "Broke every bone in left foot crushed ! knee injuries left knee replaced last yr shoulder this yr it sucks getting old but nuycynta is a god sent miracle i wish ins would cover the regular not the time release i slept much better on regular for 2 yrs oh well rules"

10 / 10
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38 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 24, 2012

For Pain "After 2 years on Percocet for back pain, my surgeon recommended I see a pain specialist. The doctor prescribed Nucynta ER and completely took me of the Percocet. The first 5 days were awful. I was taking 50 mg twice a day to get it in my system, then taking 150mg twice daily as my regular routine. I didn't think it worked at all and felt terrible because of the withdrawal from Percocet. I stuck with it and am glad I did. My mornings are much better because I'm in almost no pain whereas before, mornings were the worst. It has much less adverse effects on my short term memory, ability to focus, and ability to function more at the workplace (I'm a math teacher) than when I was taking Percocet. The negatives are that I still have evening pain."

8 / 10
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49 Report
  • Sadje...
  • Taken for less than 1 month
  • February 6, 2015

For Pain "I take 50mg ER tablet 2 X daily Once every 12 hours. It gives me an uncomfortable adrenaline rush every so often but otherwise definitely controls my pain levels. I have scoliosis. It is more of nerves in muscle pain and exhaustion."

10 / 10
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41 Report
  • Johnny...
  • Taken for 2 to 5 years
  • December 15, 2019

For Pain "I started on 50 mg of Nucynta with 4 of the 5/325 mg vicodin daily. I had Carpal Tunnel, Rotator cuff surgery and Neck surgery all related to work. My pain Dr upped my dosage to 1-100 mg Nucynta ER daily. Taking it with Vicodin during the day it seems to work ok. I get the sharp nerve pain on occassion from my neck into my arms at times. As a whole it works ok. Sometimes with chronic pain one has to search for what works best for that person. We are all different."

8 / 10
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22 Report
  • SASS
  • January 27, 2018

For Pain "I love Nucynta ER. I take different pain meds for different kinds of pain. Nucynta was prescribed when I told my Doctor I couldn't stand my legs anymore. My legs felt like huge, heavy, painful, petrified stumps. I couldn't sleep and other pain meds didn't touch the pain in my legs. Nucynta takes this pain away. And when the pharmacy couldn't get the medication for a week.....there were NO withdrawal problems.....except the leg pain came back. This year I am afraid - as no one is covering Nucynta ER. I chose a Part D plan that showed online Nucynta ER was covered. But now they are saying it's not in their new paper formulary. Back to the search....and back to LEG PAIN."

10 / 10
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28 Report
  • Flick...
  • July 31, 2014

For Pain "I have been in severe pain for 10 years. I had a 360 back surgery done on the 18th, the pain is so bad that I still have I can hardly stand it. My surgeon sent me to a pain management doctor, and he put me on. This Nucynta ER 50mg twice a day, I do not sleep, I wake up in the wee hours of the morning just screaming in pain. The pain management doctor said to give it time to work, ok have taken it for two days and no reliefs in sight. Have called and called, supposed to wait till Friday and call again, but can not take much more of this pain I am in."

1 / 10
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39 Report
  • L2ano
  • Taken for 6 months to 1 year
  • January 5, 2020

For Pain "After having a benign brain tumor removed I began suffering from horrible headaches and seizures. I fell and fractured 5 ribs and collapsed my lung. That’s when I was diagnosed with cluster headaches. I have tried so many different medications and treatments, nerve blocks, infusions, ablation. My pain management doctor started me on Nucynta ER 250 2x daily and when I have break through pain I have 2- 50 mg I can take to manage the pain. It’s tolerable and I do not wake up in agony anymore. I also use Emgality a migraine medication monthly. The combination of medications are working better then anything else. The only thing I can say is this medication his the most expensive medication I have ever paid for. I wonder what people with no insurance would do."

8 / 10
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21 Report
  • RubyR...
  • Taken for 6 months to 1 year
  • August 5, 2017

For Pain "I have chronic idiopathic pancreatitis, allodynia, gastroparesis & tarsal tunnel syndrome. I was also, just recently tested for Lupus. I was taking Norco (hydrocodone/acetaminophen) for a year until my new doc realized it was making my GI issues worse. We switched to Nucynta ER 150mg/BID & Nucynta IR 75mg for breakthrough. While they worked the first few months, I seem to be building a tolerance. I feel like the ER takes the edge off when my pain is between 4-5. But, both IR & ER cause EXCESSIVE sweating. I mean, there are days I have to change clothes multiple times daily. It's embarrassing. But, the Nucynta does not have any of the GI side effects (constipation namely) that other narcotics do."

7 / 10
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29 Report
  • HJBR
  • February 17, 2013

For Pain "My pain level was10 most of the pain from severe back problems down my left leg into my foot. After many medicines which made me groggy sick to my stomach and not able to really function. My doctor prescribed Nucynta ER. I can function without most side affects. The only side effect seemed to be like a light recall problem. When carrying on a conversation. Example names and places times. I could go all around what I wanted to say then finally. It would come to me."

10 / 10
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42 Report
  • Anonymous
  • Taken for less than 1 month
  • May 29, 2016

For Pain "This drug gave me bad reaction from the very first dose. My doctor thinks I had Serotonin Syndrome from taking this with an antidepressant. I got a fast heart rate, flushed face, restless, like taking some kind of stimulant. They cut my antidepressant dose in half which helped some but I still couldn't stand the side effects. Lots of nausea too. Pain relief was ok but not great."

2 / 10
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32 Report
  • Wambo
  • Taken for 1 to 6 months
  • December 8, 2019

For Pain "Multiple herniated discs, severe osteoarthritis in my spine and severe degenerative disc disease, my neck and lower back are the worse for me. I've tried percs, butrans 20mg patches and now nucynta 400 mgs a day. Been on it for 6 months now. Helps but certainly not a cure all! The breakthrough pain is awful and all I can take for it is arthritic acetaminophen, which does nothing . Don't miss the constipation, buzz or nausea of the other options. Biggest downside is it stops all ambition and drive!"

7 / 10
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20 Report
  • Gregor...
  • Taken for 2 to 5 years
  • July 30, 2015

For Diabetic Peripheral Neuropathy "Been on Nucynta for a while (3-4 years) for very bad neuropathy pain. Have taken it with Norco every 4 to 5 hours- has little to no side effects, within an hour after taking I can feel the pain go almost all away, can function great at work - no side effects to speak of, no problems falling a sleep, use "Kerasal NeuroCream" on hands and feet at night dulls pain enough for me to fall asleep."

10 / 10
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33 Report
  • StevieJ
  • Taken for less than 1 month
  • April 19, 2016

For Pain "I've got very severe osteoarthritis on 100% of my spine. a ruptured disk at L2 that even the best Neurosurgeons told me they couldn't fix because of all the holes in my vertebrae from the osteoarthritis so fusion won't work either. So, I've been on 15mg of Roxicodone 4 times a day for the last 6 years. Today my Dr and I decided to try a combo of 2 drugs, Nucynta 100mg and Hysingla ER 60mg Haven't taken any Roxi today just to see if the Nucynta ER helps any, and it does but not as good as the Roxi. Having to wait on the Hysingla ER until Friday. I'll report back on this after I get those and use for a week,"

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31 Report
  • Anonymous
  • April 23, 2013

For Pain "I have nevre damage due to spinal cord surgery. I have tried several long term and short term pain medications and everything made me tired that I could not work while taking the medication. The pain doctor then put me on Nucynta which I take at night and it works wonderful. I still take pain medication during the day for break thorough pain as I cannot take the Nucynta while I am working."

8 / 10
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38 Report
  • Angel...
  • Taken for less than 1 month
  • November 30, 2016

For Pain "This medicine made me dizzy and didn't help me with the pain at all...I was vomiting after about six hours....is nothing like I'm use too... There is something in this medicine that's isn't good and I wouldn't recommend it to anyone."

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28 Report
  • Itali...
  • July 22, 2016

For Diabetic Peripheral Neuropathy "My step dad was using this Medication for less than two weeks before the pill itself killed him, proof is in the death certificate. He was not abusing either. He complained from day one of taking it of many side affects. Sleeplessness dizziness trouble urinating hallucinations still felt pain couldn't stand without falling etc,. He asked his doctor to be off the pill and they told him to wait until they see him the following Month. Also fault in there practice too."

1 / 10
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28 Report
  • Anonymous
  • Taken for less than 1 month
  • July 30, 2014

For Pain "I was recently changed from Oxycontin 20mg ER x2 twice a day with 5mg oxycodone three times daily for breakthrough pain. That combination did nothing for me. I am now on Nucynta ER 150 mg twice per day with Opana 10mg 3 per day for breath through pain. To me I find myself using my breakthrough medication more than I did with the Oxycontin. I have only been on the Nucynta for a week now and I am hoping that the relief will get better the longer I am on it."

5 / 10
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32 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.