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Nucynta ER and Nausea: What Users Say

Nausea: mentioned by 6 users (7.4%)

Based on user experiences from 81 Nucynta ER reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 7.4%
constipation 4.9%
dizziness 4.9%
drowsiness 4.9%
insomnia 4.9%
tiredness 4.9%
pain 3.7%

Reviews for Nucynta ER

Commonly mentioned side effects
  • ste...
  • March 10, 2016

For Pain "I had 17 surgeries on hands, arms, elbows, and shoulders, 11 on the right side, the rest on the left side. I have very chronic pain nerve damage on both hands, elbows, arms, and shoulders. I take 1 Nucynta and 2 Roxicodone every 6 hours, the pain is about a 10, really bad. When I take these meds, it goes down to around 5 or 6. It helps a lot. I would recommend this. I'm disabled, it helps me to function. I wish it would help more, but it doesn't have too many side effects. I've been taking them for a few years. You get some nausea, but I take Zofran for that. What I don't like is the government trying to tell us to cut down. I take 4 Nucyntas and 6 Roxicodone a day. That's the most I can cut down to because of my chronic pain. The people that are hurt are the ones that suffer."

5 / 10
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93 Report
  • tir...
  • Taken for less than 1 month
  • July 6, 2018

For Pain "Just started taking this, was on Oxycodone 10/325 4 times a day, was willing to give it a shot. It's horrible. I keep wanting to throw up all day long, it feels like I am going through withdrawals, foggy as heck, missing work. Never had these issues before. They are making the opioid issue so bad that people who really need the pain meds are having to take things like this. I have had 4 neck surgeries so far, the pain is ridiculous. Before I found the Oxy, I was barely able to move around, once I got on that regimen, I was able to work every day, function like normal. Now I'm back to just feeling sick every day, foggy as heck, not wanting to do anything, just cry. This sucks."

1 / 10
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59 Report
  • Lul...
  • Taken for 1 to 6 months
  • December 13, 2016

For Pain "I have 4 slipped discs and a self-fusing spine, and I'm only 36. I have terrible OA in my spine that's hereditary. I failed epidural injections. The nerve pain kept me in bed crying most days, and I couldn't be a wife or mom. I started on Norco, then moved to Oxycodone. They added Neurontin, and nothing took care of the burning, shooting pain that was at the base of my skull and down my left arm. I got intermittent relief for one year. I changed doctors, and they put me on Nucynta ER 250 mg once a day! I can honestly say I am pain-free. I only take this and an anti-inflammatory. I will say the consistent side effect is nausea, vomiting, and no appetite. I don't mind it, as I'm finally pain-free, and I just eat small meals!"

9 / 10
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57 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • May 29, 2016

For Pain "This drug gave me a bad reaction from the very first dose. My doctor thinks I had serotonin syndrome from taking this with an antidepressant. I got a fast heart rate, flushed face, restless, like taking some kind of stimulant. They cut my antidepressant dose in half, which helped some, but I still couldn't stand the side effects. Lots of nausea too. Pain relief was okay, but not great."

2 / 10
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32 Report
  • HJB...
  • February 17, 2013

For Pain "My pain level was 10, most of the pain from severe back problems down my left leg into my foot. After many medicines, which made me groggy, sick to my stomach, and not able to really function. My doctor prescribed Nucynta ER. I can function without most side effects. The only side effect seemed to be like a light recall problem when carrying on a conversation. Example: names, places, times. I could go all around what I wanted to say, then finally it would come to me."

10 / 10
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42 Report
  • Wam...
  • Taken for 1 to 6 months
  • December 8, 2019

For Pain "Multiple herniated discs, severe osteoarthritis in my spine, and severe degenerative disc disease, my neck and lower back are the worst for me. I've tried percs, Butrans 20 mg patches, and now Nucynta 400 mg a day. Been on it for 6 months now. Helps, but certainly not a cure-all! The breakthrough pain is awful, and all I can take for it is arthritic acetaminophen, which does nothing. Don't miss the constipation, buzz, or nausea of the other options. Biggest downside is it stops all ambition and drive!"

7 / 10
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20 Report

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