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Nucynta ER and Insomnia: What Users Say

Insomnia: mentioned by 4 users (4.9%)

Based on user experiences from 81 Nucynta ER reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 7.4%
constipation 4.9%
dizziness 4.9%
drowsiness 4.9%
insomnia 4.9%
tiredness 4.9%
pain 3.7%

Reviews for Nucynta ER

Commonly mentioned side effects
  • Nie...
  • Taken for less than 1 month
  • March 20, 2018

For Pain "Was on Opana ER 20 mg twice a day with Oxy 5 mg 1-3 times a day. Was doing well, not using the IR very much. Pain clinic doctor no longer issuing prescriptions for Opana. I was put on Nucynta 100 mg twice a day in place of Opana. The last five days have been very difficult. I can't sleep, literally. I have zero appetite and have to force myself to eat some crackers and cheese. The medication wears off after 8-9 hours with strong withdrawal symptoms. So I have to take breakthrough meds just to calm the withdrawal. My hands shake and I feel so weird. Like depression. I can't take this medication any longer. I believe our bodies all react differently to medications, and for me, this is not a good fit."

1 / 10
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55 Report
  • gra...
  • Taken for 6 months to 1 year
  • October 10, 2014

For Pain "I could not deal with the side effects of OxyContin or hydrocodone. Too much dizziness and severe itching. Unable to get restful sleep. Nucynta ER 50, 2 times a day has been MUCH better for me. Very little side effects and only for the first couple of weeks. I sleep better too. Only objection is that it wears off after only about 5 hours. So I have to take hydrocodone occasionally."

8 / 10
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71 Report
  • Emm...
  • Taken for less than 1 month
  • April 11, 2022

For Pain "I've had fibromyalgia for 16 years, degenerative disc disease, 2 failed back surgeries, and osteoarthritis. I was on Belbucca but was having a lot of pain still. I was put on Nucynta ER 150 mg. The first couple of days were okay. But after a week, my blood pressure was really high. Then I started getting hot flashes, chest tightness, coughing, and insomnia. I called my pain management, and they told me to stop taking it, but I have to wait 2 weeks for my next appointment. That's sadistic! I went to the ER, and they said I had bronchitis. The next day, I thought the bronchitis was causing my symptoms, and I was in pain, so I took a Nucynta. Nope, it's the medicine! About 30 minutes after, maybe my chest got tight and started coughing, and later got hot flashes. Not a good medicine!"

1 / 10
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4 Report

Frequently asked questions

  • Cha...
  • February 5, 2013

For Diabetic Peripheral Neuropathy "Nucynta ER has worked wonderfully for pain relief for me. It does keep me up if taken at bedtime, though. You can find a coupon online to keep your monthly costs down."

9 / 10
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60 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.