Nucynta ER and Constipation: What Users Say

• PES...
• Taken for 1 to 6 months
• August 7, 2018

For Pain "I have had multiple different surgeries and live with chronic pain. I've been taking three Percocet 5-325 mg per day. The pain control would only last for around 3-5 hours. The constipation that comes along with the above med was unreal. I then ended up forming stage three hemorrhoids and had to have a hemorrhoidectomy, which was the worst! The pain medicine also made my depression worse, which I did not need! My pain clinic doctor recommended Nucynta ER 50 mg every twelve hours. There were two benefits in taking Nucynta ER 50 mg: first, it was around-the-clock pain control; and secondly, it eliminated my hard stool and constipation. It was increased to 100 mg because of my pain levels. I was still dealing with breakthrough pain and was given oxycodone 5 mg, but once again, it caused more depression and constipation immediately! I’m going to have to stop taking the oxycodone and talk to my pain clinic doctor about increasing my dosage of Nucynta to 150 mg twice per day."

• Rub...
• Taken for 6 months to 1 year
• August 5, 2017

For Pain "I have chronic idiopathic pancreatitis, allodynia, gastroparesis, and tarsal tunnel syndrome. I was also just recently tested for lupus. I was taking Norco (hydrocodone/acetaminophen) for a year until my new doctor realized it was making my GI issues worse. We switched to Nucynta ER 150 mg/BID and Nucynta IR 75 mg for breakthrough. While they worked the first few months, I seem to be building a tolerance. I feel like the ER takes the edge off when my pain is between 4-5. But both IR and ER cause excessive sweating. I mean, there are days I have to change clothes multiple times daily. It's embarrassing. But the Nucynta does not have any of the GI side effects (constipation, namely) that other narcotics do."

• Wam...
• Taken for 1 to 6 months
• December 8, 2019

For Pain "Multiple herniated discs, severe osteoarthritis in my spine, and severe degenerative disc disease, my neck and lower back are the worst for me. I've tried percs, Butrans 20 mg patches, and now Nucynta 400 mg a day. Been on it for 6 months now. Helps, but certainly not a cure-all! The breakthrough pain is awful, and all I can take for it is arthritic acetaminophen, which does nothing. Don't miss the constipation, buzz, or nausea of the other options. Biggest downside is it stops all ambition and drive!"

• Wil...
• Taken for less than 1 month
• December 24, 2017

For Pain "The first dose made me somewhat woozy. However, the next 3-4 were like taking aspirin. USELESS! I am sure that this drug causes diarrhea! Also, yesterday morning I had body aches, which felt like I had the flu! It is common for most opioid users to suffer from constipation; however, I take Miralax every other day to avoid this problem."