Skip to main content

Sulfamethoxazole / trimethoprim for Sinusitis User Reviews (Page 3)

Brand names: Bactrim, Bactrim DS, SMZ-TMP DS, Co-trimoxazole, Septra, Septra DS, Bactrim Pediatric, Bactrim IV, Bethaprim Sulfatrim Pediatric Bethaprim Pediatric …show all brand names

Reviews for Sulfamethoxazole / trimethoprim

Commonly mentioned side effects
  • Chr...
  • February 25, 2016

"I had a sinus infection 20 years ago that spread to my left eye and left frontal lobe of my brain. I had surgery on my sinuses, left eye, and my left temporal lobe of my brain removed and now have a plastic plate on the left side of my head. So I have frequent sinus infections and headaches. I was given generic Bactrim from the VA. I have taken it 2 days and my sinuses have cleared up. I am still having headaches but now have nausea, diarrhea, and stomach pains. I just hope it gets rid of the infection."

7 / 10
Was this helpful?YesNo
2 Report
  • Bel...
  • November 26, 2019

"For me, this medication is an absolute nightmare! After about 8 days on this med, I started feeling intense muscle cramping, fever, and chills. So I stopped taking it. To my surprise, Bactrim can have horrible side effects, which I experienced every one of them. I had a 101-degree fever, chills, skin rash, heart palpitations, aches, and pains beyond what any human should suffer for 5 days afterwards. I thought I was going to have a heart attack and that would be it for me. When my body told me to sleep, I slept. And I did a lot of sleeping because I knew that my body seriously needed the rest to try and repair itself from all of the side effects I stated. It took me 10 full days to even feel semi-normal again. If the rating system would allow, I would give this drug a negative 10 for being so destructive."

1 / 10
Was this helpful?YesNo
0 Report
  • Luc...
  • Taken for less than 1 month
  • April 3, 2023

Sulfamethoxazole / trimethoprim "I was put on Bactrim for 10 days and ended up at the ER. I have terrible headaches, I passed out, dizziness, so weak I could barely get up. Thought I was going to die before the doctor figured out that I was reacting to the medication."

2 / 10
Was this helpful?YesNo
0 Report

Frequently asked questions

  • Fus...
  • Taken for less than 1 month
  • April 17, 2014

Sulfamethoxazole / trimethoprim "My body responds to sulfur products. After two days on Bactrim, I noticed a difference. By the 4th day, I was back to myself. It really helped me."

10 / 10
Was this helpful?YesNo
45 Report
  • Anonymous
  • August 30, 2011

Sulfamethoxazole / trimethoprim "Great antibiotic, cleared away my sinusitis, however, been an insomniac for the past couple of days."

9 / 10
Was this helpful?YesNo
42 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Anonymous
  • Taken for 1 to 6 months
  • February 5, 2020

Sulfamethoxazole / trimethoprim "If you are taking Bactrim, you need to be on probiotics so you don't get cramps and nausea. It works."

10 / 10
Was this helpful?YesNo
19 Report
  • Anonymous
  • February 9, 2009

Sulfamethoxazole / trimethoprim "Works okay after a couple of days with no side effects, but everybody is different."

8 / 10
Was this helpful?YesNo
40 Report
  • Ell...
  • Taken for less than 1 month
  • October 7, 2018

Sulfamethoxazole / trimethoprim "Hope I'm not responding prematurely, but I feel improvement within 24 hours. Still have 12 days to go."

8 / 10
Was this helpful?YesNo
17 Report
  • Anonymous
  • February 9, 2010

Sulfamethoxazole / trimethoprim "It always gets the job done soon when you first start taking the medication."

10 / 10
Was this helpful?YesNo
31 Report
  • Anonymous
  • February 3, 2009

Sulfamethoxazole / trimethoprim "Horrible headache and stomach ache. Had to discontinue."

3 / 10
Was this helpful?YesNo
29 Report
  • nic...
  • December 16, 2013

Sulfamethoxazole / trimethoprim "I've been on it for 6 days now, and I feel the same as I did before. This is my first time taking it for a sinus infection. I guess it doesn't work for me."

4 / 10
Was this helpful?YesNo
22 Report
  • itc...
  • May 3, 2009

Sulfamethoxazole / trimethoprim "Was prescribed Bactrim for a combination of sinusitis and a urinary tract infection. After two pills, I got a yeast infection. Not sure the medication is working to make me feel better or not."

3 / 10
Was this helpful?YesNo
25 Report
  • she...
  • November 15, 2013

Sulfamethoxazole / trimethoprim "Took one dose of Bactrim for sinusitis/bronchitis, and 3 hours later, my face was red. 1 hour following, my face, arms, and hands broke out into hives. Had to discontinue and call the doctor."

1 / 10
Was this helpful?YesNo
18 Report
  • Sld...
  • Taken for less than 1 month
  • July 25, 2014

Sulfamethoxazole / trimethoprim "Usually clears up any infections, but does sometimes cause extreme nausea and yeast infection."

10 / 10
Was this helpful?YesNo
13 Report
  • Pau...
  • Taken for less than 1 month
  • October 17, 2017

Sulfamethoxazole / trimethoprim "This worked fine. I have no side effects. The people above seem to have an allergic reaction to this medication. Obviously, stop taking it. You don't need a Dr. to tell you that."

10 / 10
Was this helpful?YesNo
10 Report
  • NYC...
  • Taken for less than 1 month
  • December 8, 2019

"Excellent medicine. No side effects at all. I have taken Augmentin, and it only works on a limited number of bacteria. This antibiotic is the best on the market for sinus infections."

9 / 10
Was this helpful?YesNo
7 Report
  • hfr...
  • Taken for less than 1 month
  • January 16, 2015

Sulfamethoxazole / trimethoprim "The pressure in my head is gone, but I have been getting extreme nausea and fatigue since I started it 5 days ago."

3 / 10
Was this helpful?YesNo
11 Report
  • Son...
  • Taken for less than 1 month
  • April 12, 2021

Sulfamethoxazole / trimethoprim "I use this med yearly for springtime sinus infection. Works wonderfully for me. No side effects, ever. Probably for 5 or more years now."

10 / 10
Was this helpful?YesNo
5 Report
  • Sus...
  • April 10, 2016

Sulfamethoxazole / trimethoprim "Severe diarrhea, severe nausea, and vomiting after 2 doses."

1 / 10
Was this helpful?YesNo
8 Report
  • ljk...
  • Taken for less than 1 month
  • April 26, 2022

Sulfamethoxazole / trimethoprim "This is the only drug that helped eliminate my sinus infection. I had already taken Z-packs doses back to back without success."

10 / 10
Was this helpful?YesNo
2 Report
  • In ...
  • Taken for less than 1 month
  • December 3, 2015

Sulfamethoxazole / trimethoprim "Yeah, did this for seven days. Just got out of the hospital after a full-body rash (including feet, hands, and face, required them to put me on IV antibiotics for two days). Fun times."

1 / 10
Was this helpful?YesNo
9 Report
  • Anonymous
  • Taken for less than 1 month
  • September 17, 2021

"It was the one drug that worked when Augmentin did not. While in the military, Augmentin was the #1 prescribed drug for sinus issues, and it never worked for me. Septra worked like a charm."

10 / 10
Was this helpful?YesNo
0 Report
  • Red...
  • Taken for less than 1 month
  • January 18, 2021

"Very nauseated. Clindamycin much more effective."

1 / 10
Was this helpful?YesNo
0 Report
  • jsz...
  • Taken for less than 1 month
  • May 28, 2014

Sulfamethoxazole / trimethoprim "Taking this for sinusitis. I am an adult taking it in suspension, as I have trouble swallowing pills. It says grape and is purple in color, but it tastes terrible."

5 / 10
Was this helpful?YesNo
6 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Sinusitis

Care guides

Symptoms and treatments

Medicine.com guides (external)