Sodium hyaluronate User Reviews & Ratings (Page 5)

• Gra...
• Taken for 1 to 6 months
• February 16, 2020

For Osteoarthritis "I had my left knee injected with Durolane in December 2019. I had previously had successful injections of Synvisc over a period of four years, and that gel worked great. This time, United HC approved both Synvisc and Durolane. I wanted the Synvisc, but the doctor wanted to spare me three injections. I stupidly accepted her advice and did the Durolane. Holy moly-my knee still hurts like anything. All the time. It's on fire. My new doctor said I may have to wait another six months before he could inject Synvisc. My advice-stay away from Durolane."

• jci...
• Taken for 1 to 6 months
• August 25, 2020

For Osteoarthritis "This is the 6-month after injection report. The first 3 weeks I had swelling due to too much Durolane fluid in my knee. Months 2, 3, 4, and 5 got better, morning stiff but flex out as the day goes along. Swelling started in month 6, not pain but sore when walking. My 3 Synvisc treatments worn out after 3 to 5 months. So I will get my second Durolane injection this week, see if it's as good as the first one."

• ham...
• Taken for 1 to 6 months
• November 20, 2022

For Osteoarthritis "Almost 7 wks since I got the injections, and I still cannot walk. Knees will not bend. Terrible time going up and down steps. Hard time getting comfortable in bed at night. If I'd known this was going to cripple me, I never would have, and will never again, get this injection. Shame on you, Durolane!"

• Lin...
• Taken for less than 1 month
• December 12, 2020

For Osteoarthritis "Had Durolane shots on both knees two days ago. Heard positive results from the company and pain doctor. After reading other comments, hope I will not be feeling pain too long. Have pain now, stairs are a challenge. Am taking Tylenol for arthritis. Wait and see, I guess."

• Joh...
• December 4, 2014

For Osteoarthritis "I am an active 60 y/o male; have had 2 surgeries to fix meniscus tears on the left knee; also arthritic in that knee. I am 1 week out from the 3rd injection. 1st shot was good - no side effects; 2nd shot - some increased swelling and stiffness; 3rd shot ok; one week out and I notice that I am not sore after sitting at my desk for an hour or more. I actually have to start getting used to trusting my knee when I stand up again! Definitely helped! I have not given it the acid test as I am a backpacker and I would usually get significant pain after the first couple of miles hiking. Initial reaction is that my knee is not perfect with 20% of my meniscus left, and I do still have some pain, but the shots did help. No complaints."

• Yog...
• Taken for 6 months to 1 year
• February 17, 2015

For Osteoarthritis "I am 65 with osteoarthritis in both knees. My orthopedist gave me a round of cortisone, saying if it helped, the Euflexxa most likely would as well. Luckily, the cortisone helped; I proceeded with three sets of injections. Both the cortisone and the first two sets of Euflexxa were excruciatingly painful, all administered by different people with scan guidance. The fourth set (third Euflexxa) was absolutely painless due to the skill of the person administering. I almost didn't finish the series because of the pain of the injections. However, in the long run, the Euflexxa gave me five months totally pain-free. One knee has started to become painful again, but the other is still great at eight months. Time for another round of Euflexxa!"

• cha...
• Taken for less than 1 month
• March 3, 2021

For Osteoarthritis "I have been getting knee injections for several years with great results. Last week, the physician gave me Gelsyn-3 instead of my regular one. I had many adverse effects from the drug: edema, joint pain, heat on the knee, bruising, etc. Went in today for my second injection and found out what happened. I was given Gelsyn-3 because the physician said they were reimbursed for a higher rate than Gelsyn-3. I called Bioventus and reported the adverse effects from their drug. They were very nice and recorded the information. I also contacted Medicare. Long story short, will be seeing another physician at a different practice because of this. Physicians should always discuss with their patients when something is changed so that the patient can make the decision. Not even an apology that I had a negative reaction."

• Fru...
• Taken for less than 1 month
• January 16, 2022

For Osteoarthritis "Had my 1st shot and felt an immediate improvement, was able to get up and go with little assistance from a cane. Was able to walk steps and around the block, felt much better. Went in for my 2nd shot the following week and immediately felt sharp pressure pain during the injection. I couldn't even stand up to leave, had to sit back down for a few minutes or so. Feeling very frustrated, I walked in fine, and now I'm having a rough time walking after the 2nd shot. 4 days later, my knee is still swollen and seems to be getting worse. I've iced and used a heat pad for pain, and now am back on crutches. I fear going in for the 3rd shot. I feel that had I stopped at 1 shot, I would be okay, but my doctor insists I need 3 consecutive shots."

• Hur...
• April 24, 2024

For Osteoarthritis "I received Gelsyn-3 injections in both knees. One injection in each knee for 3 weeks. I have osteoarthritis bone on bone in both knees. My full review can be found on the reviews page 1 (under Hurting) as they don't want us to use our real names here in the reviews. I received these terrible injections in 2020 and I have never regretted anything more. My knees and femur bones pain and the thigh muscle pain is excruciating, also the swelling and feet pain. I used to be an active woman who walked every day. I gardened, worked in my flower bed, and got around fine before these injections, now I can't do any of these things. At this point in time, I feel that I have passed the point of the side effects of this drug and believe that I have been injured. This is my fourth year after receiving this horrible drug. Walking is almost unbearable. My life will never be the same. I went in for pain relief and now I feel like I am becoming a cripple."

• Anonymous
• August 31, 2011

For Osteoarthritis "I get Supartz injections in my osteoarthritis ankle at least every 5 to 6 months. It is truly a miracle. I have 99.9% relief. I just wish the insurance would cover the injection. They won't cover it because they state the ankle is not a major joint?"

• Ikn...
• March 1, 2020

For Osteoarthritis "Try orthotic insoles first, then Durolane. I had knee pain diagnosed as osteoarthritis, and it got worse over time. In October, I could not walk, the pain of bone on bone was impossible. Signed up for double knee replacement. In the meantime, tried orthotic insoles. What a lifesaver! Cartilage was worn out on both knees on the inside only. This indicated a biomechanical problem. The doctor preparing the insoles noted I had flat feet, and these insoles straightened out my walk. This allowed the inflammation to subside as the load was now spread. A few months later, to stabilize the knees, I tried Durolane. One week into it, and some stiffness and discomfort in the injected knee, but I can feel a big reduction in pain and more stability. The injection was no problem. Now my worse injected knee is better than my better non-injected knee. If you have addressed the underlying issue, maybe Durolane becomes more effective. Good luck!"

• Al2...
• Taken for 2 to 5 years
• July 16, 2024

For Osteoarthritis "I read these reviews 2 years ago after my physio recommended it over Ostenil. He then took it up with the Durolane rep, whose response was that the pain people get is when it is injected into tissue outside of the capsule. There shouldn't be any pain from the Durolane. So today, I had my 3rd lot of Durolane injections (both knees). Immediately no limp. They now offer lidocaine prior to the injection, with it being a gel. I recommend taking the lidocaine injection as Durolane on its own is uncomfortable due to its thickness going in. We've also recommended it to 3-4 other people who have all gone and had it. All are very happy. Both knees $900, worth every cent."

• Pai...
• Taken for less than 1 month
• October 7, 2018

For Osteoarthritis "Got first shot 4 days ago, and my knee has been swollen every day since. Ankles are both swollen, cannot bend knee, and scared to even move...especially walk. Not sure I will make it to where I need to go. Before the shot, at least I could get around, now what am I to do? Knee replacement seems to be the only option. Contemplating!"

• But...
• Taken for less than 1 month
• December 1, 2018

For Osteoarthritis "I had injections in both the right and left knees at the same time. The right knee did okay, but the left knee was absolutely horrible. Within 4 hours of injections, I had the most horrific reaction. The pain was the most extreme pain. I had painkillers, and it would not relieve the pain. It was so bad I wanted to call an ambulance. The only reason I didn't was because my bedroom is upstairs, and I couldn't make the trip downstairs. I knew the only way the paramedics could get to me was by breaking a 1500-dollar door down. So I kept taking more painkillers, and finally, after 7 hours, I had relief. Since the injections, I have severe leg cramps in both legs, wow, over the top! Itching over my body, bad lower back pain, RLS, and nausea. This continues every day. My legs barely move. Before treatment, I was walking 2 1/2 miles daily, and I'm 65... obviously, I had a severe allergic reaction. Would not ever recommend."

• Bil...
• Taken for less than 1 month
• August 25, 2020

For Osteoarthritis "I'm a 63-year-old male. Bone on bone in the right knee. I got this Durolane injection today at about 11 a.m., and it hurt like anything. I was okay until about 5 p.m. at work today. Now the knee hurts so much, and I'm in a lot of pain. Sure hope this pain subsides."

• Pam...
• Taken for 2 to 5 years
• February 11, 2025

For Osteoarthritis "My first visit to my doctor for osteoarthritis in both knees, I could hardly walk. I was in so much pain, and the pain was unbearable. I have been getting Euflexxa injections now for almost 4 years. I have absolutely no pain at all. I get one injection in each knee three weeks apart every 6 months. This is a miracle drug. It has kept me very mobile and active. I am almost 81 years old, and last year went back to work in a women's clothing store. Loving our customers and assisting their shopping needs keeps me young."

• Mad...
• Taken for less than 1 month
• June 5, 2015

For Osteoarthritis "I'm a 55 y/o female who suffers from severe rheumatoid arthritis, osteoarthritis, fibromyalgia, and polyneuropathy. I had my first injection yesterday. The injection was a bit more of a sting than most shots, and there was a brief period of pressure, but overall, not that painful. It may or may not be related to Euflexxa, but a couple of hours later, I was curled up in bed in incredible inflammatory pain. I received the injection around 2:30 pm, the inflamed state began around 4:00 pm, but by 11:00 pm or so, I was feeling great! I didn't get to sleep until after 3:00 am, slept in to 10:00 am, and woke up a bit weak. After meds and a cup of soup, I was revived and ready to go! I ran my errands full of energy! It felt weird that I wasn't limping!"

• Jef...
• Taken for 1 to 6 months
• December 31, 2021

For Osteoarthritis "I've had cortisone shots in both knees in the past, which helped with the minor pain and swelling at the time. A couple of months ago, my ortho suggested the Gelsyn-3 shots for a more long-term treatment. It's been 5 weeks since my last Gelsyn-3 shot, and I can barely walk across the parking lot, or pasture in my case. I now have severe pain and excessive swelling in both knees, especially in the area where the shots were administered. Now the pain has moved into my thigh and calf muscle as well. I struggle to straighten my legs out. And getting up after sitting down is impossible without assistance. Since taking the Gelsyn-3 shots, my quality of life has significantly declined in a very short period of time. I have no idea why there are such differing results, but I would warn that you carefully consider the significant downside if there is a negative reaction that I and many others have experienced."

• Jas...
• December 5, 2015

For Osteoarthritis "I've had 3 series of Euflexxa with good relief from bone-on-bone pain as long as I don't overdo. They make it easier to walk and reduce general pain and stiffness. They also help significantly with preventing my knee from going into a sublux position. The injections themselves aren't painful, just uncomfortable. My doctor uses a topical anesthetic and is very gentle. Any pain is brief. I have some very minimal bleeding and swelling at the injection site and take it easy afterward. I'm so grateful for Euflexxa. I received injections of Synvisc (similar, but with actual rooster comb as opposed to a synthetic) before. They worked great and I needed only 1 shot, not 3, but like many, I had a severe painful reaction with repeat injections."

• Pul...
• Taken for 1 to 6 months
• April 7, 2019

For Osteoarthritis "I got no relief after I started my Supartz injections, so I just waited and hoped that eventually I would get some relief. I received the 5th injection 2 weeks ago, and my pain now is worse than ever, and some days I’m almost immobile. I am not able to even step off of a curb without help, and some days the pain is so bad that I can't get out of bed. I opted for it because of the positive reviews. I’m sure it works for some people. I’m glad I tried, even though it didn’t work for me."

• vic...
• Taken for 5 to 10 years
• August 4, 2018

For Osteoarthritis "I love Euflexxa! I've had 5 rounds of it over 5 years. Yes, I'm bone on bone, but still have a bit of space in my knee joint for the medication to get in and be useful. Since I've had 2 orthopods tell me that studies show that knee injections done blind only actually get in the joint space 2 out of 3 times (despite the claimed skill of the doctor in doing injections), I have the Euflexxa injected under fluoroscopy by a radiologist to be sure the medication goes to the correct space (my husband is a radiologist who suggested it this way if I wanted to be sure). Euflexxa is the difference between me being able to walk (limp) 20 feet in severe pain and me being able to walk for long distances for many hours WITHOUT pain. I'm not ready for knee replacement mentally, and this is a wonderful thing. I've never had any reaction and find pain subsides after the 2nd injection and lasts fully for 6 months, and then I start hurting again and need another round at about 8 to 10 months out."

• Sug...
• Taken for less than 1 month
• February 26, 2021

For Osteoarthritis "Had the entire series of Gelsyn. My knee feels worse than before. I can barely walk or put any weight on the knee. I have had low back pain, and I've also had a cramping sensation and spasm in the knee. The pain is excruciating. I'm very disappointed, as I'm not wanting surgery. I personally would not recommend this drug."

• Gra...
• Taken for less than 1 month
• April 26, 2017

For Osteoarthritis "Osteoarthritis is part of my life in hips, shoulders, ankles, and, most of all, those knees. My knees are bone-on-bone, and cortisone (not good for long term) is not long-lasting. Noting the complications and side effects of total knee replacements, to say nothing of pain and rehab, I am not interested in giving up my golf and life for months. My ortho doc suggested Euflexxa a year ago, and as a last resort, I agreed. I had my third week of injections yesterday, and all I can say is that I have had a HUGE improvement. On a scale of 0-10, my pain was 9.9, and now I am at minimal discomfort around a 3. Hoping it lasts for the full six months. It is wonderful to go up and down stairs forward rather than turning sideways."

• Ale...
• October 19, 2019

For Osteoarthritis "I have osteoarthritis, bone on bone, both knees. The pain in the right knee is worse than the left. I had no relief from a cortisone injection. The right knee was injected with Euflexxa. About 72 hours post-injection, I developed bruising and swelling in the area that was injected. I was nauseous, hot, and sweaty, but had no fever. The knee was extremely painful, with increased swelling. Nothing relieved the pain. The doctor aspirated fluid and sent it for analysis and sent me for blood work. Results were normal. My experience with Euflexxa has been a nightmare. I still have pain at night and cannot sleep, and there is a constant nagging pain in the area where injected that is hard and extends upward a few inches. The doctor cannot tell me what happened. He has referred me to a surgeon to discuss knee replacement. I am thoroughly depressed over the entire experience, not to mention the constant pain."

• Unl...
• Taken for 1 to 6 months
• September 4, 2022

For Osteoarthritis "I do not normally write reviews, but I believe it is my duty to let those that wish to have a Durolane injection know of my awful experience. It has been a little over 2 months now, and my knees still have not healed from these injections. Unfortunately, I got injections in both knees. Had I known, I would have only tried one knee at a time. At first, I couldn’t walk for 3-4 days, but I was optimistic as I have a wonderful doctor, and he has been taking very good care of me for the past 10 years. I believed after a week or so I should start to feel some relief. That was not the case. I am still in agony every single day. I’m sure some have had good experiences, but unfortunately, I was not one of them. I will never tell anyone to get a Durolane injection, as there is a chance they may end up like me…suffering every day of my life! Best wishes to those who wish to take a chance with this terrible medication."