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Selegiline User Reviews & Ratings (Page 3)

Brand names: Emsam, Eldepryl, Zelapar, Atapryl

Selegiline has an average rating of 7.9 out of 10 from a total of 65 reviews on Drugs.com. 77% of reviewers reported a positive experience, while 12% reported a negative experience.

Reviews for Selegiline

  • Happy
  • Taken for 5 to 10 years
  • March 31, 2018

For Depression "60 yr old male. I take 20mg/day of Selegiline, at breakfast, for depression, for over 6 years. Side effects are two: a) if I drink coffee in the afternoon I tend not to go to bed before 12:00 AM and b) sometimes it's hard to concentrate and I can get very easily distracted."

9 / 10
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11 Report
  • SamBF...
  • Taken for 1 to 2 years
  • January 3, 2023

For Depression "Emsam patches 9mg helped me effortlessly find the motivation to grow my business every day. Only negative side effect is that it seemed to have increased my tolerance for risk to a level I could not handle."

8 / 10
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3 Report
  • Anonymous
  • July 11, 2008

For Depression "Having tried just about everything out there, I was using an MAOI for years, but didn't realize how foggy I was feeling until I started using the Emsam patches. I can think more clearly, which is huge, but I still have to really push to do most things. They are the best thing I've tried."

9 / 10
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19 Report

Frequently asked questions

  • BtrLv...
  • Taken for 1 to 2 years
  • December 14, 2023

For ADHD "Selegiline has been a godsend for my ADHD/Bipolar 2. It is non-addictive, and it does a satisfactory job at controlling my symptoms of amotivation, sustained focus, and general mood. I feel that it also has cognitive enhancing effects that don't get interrupted by the feeling of the medication, which was my problem with amphetamines and methylphenidate. The way those medications feel good is distracting in and of itself and I believe leads to more focus for sure, but a lower quality of it. Selegiline does not have this problem, so I feel it is superior in the aggregate. Also, it is much milder on the body than mainstream stims, so I feel it is better from a health standpoint too. It inhibits MAO-B which degrades dopamine, causing neurotoxic by-products, making it neuroprotective where other stims are not. If you want healthier, non-addictive, baseline stimulation, look no further. Great drug!"

10 / 10
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1 Report
  • edie
  • October 6, 2007

Selgene (selegiline) for Depression "I have been suffering from major depression for over 8 years and nothing has really relieved it; Prozac would work temporarily, but soon stopped. I have been on Emsam for almost 6 weeks and my depression isn't gone, but it is better. I have not had any side effects and now I have hope that it will work and I finally have a shot at a "normal" life. Good luck to everyone that needs and tries it!"

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16 Report

Are you taking this medicine?

  • M Rod...
  • September 29, 2015

For Depression "Very effective. Diagnosed bipolar type II. Helps a lot with atypical depression type symptoms, like lethargy and slow thought processes. Messes up my sleep though, and can make me a bit cranky and irritable. Anyone know how to deal with the insomnia? I find it hard to fall asleep, and do not want to take benzodiazepines due to the addictive properties."

8 / 10
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8 Report
  • Tess
  • Taken for 10 years or more
  • September 21, 2022

Emsam (selegiline) for Major Depressive Disorder "I have been on Emsam since 2007, when it first came out. Started on 12 mg patch then down to 9 and then down to six which I have been on for 10+ years. I tried all SSRI with minor and limited time help. It has been true blessing. Insomnia has been constant problem. Now taking 300 mg gabapentin and .25 lorazepam with patch about 9 p.m. and falling asleep after midnight. Sleeping well most nights. Tremors and fine motor skill weakness are my main problematic symptoms. I am 74 year old female.I would highly recommend Emsam. Not many problems with food or medicine. I am careful with food and drink selections and have had a few reactions. Hair dye with MSG, eye drops for numbing caused me spike in BP also I did have a hospital stay for spike due to old mushrooms but not bad for this many years."

9 / 10
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  • EndTh...
  • Taken for 1 to 6 months
  • August 9, 2022

For Major Depressive Disorder "Have been struggling with MDD, PTSD & GAD 4 years. Given that a plethora of therapeutic modalities did absolutely nothing 4 me, I gave up on standard therapy & figured that I’d have 2 go 2 meds & other things 2 try to get back 2 a healthy headspace, from which I had long since fallen. Over the course of the past 10 years or so, I have tried a ridiculous abundance of pharma meds, “natural remedies,” supplements, & illicit substances on my path to betterment. The only things that EVER had a positive affect on my psyche & mental health in general, were Lithium Orotate (not the stuff given at ultra high doses in clinical settings [i.e. crazy house]), Kratom (although its effects 4 me are short-lived), and psychedelic substances — which saved my life. Selegiline is one more med I can add 2 the list of doing absolutely nothing 4 me. No downsides, but also no benefit 2 taking it. Hence my neutral review."

5 / 10
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  • bagel...
  • September 19, 2008

Emsam (selegiline) for Depression "First drug to work for me in 30 years."

9 / 10
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71 Report
  • Anonymous
  • December 22, 2010

Emsam (selegiline) for Depression "It really does work, the one side effect you have to overcome is it makes it difficult to sleep at night."

10 / 10
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57 Report
  • Downerx
  • July 26, 2010

Emsam (selegiline) for Depression "Tried Effexor, Wellbutrin, Paxil, Zoloft in the past with no results. EMSAM has brought me out of it after seven years. Only a little localized skin irritation."

8 / 10
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58 Report
  • Boo_Cat
  • February 13, 2011

Eldepryl (selegiline) for Parkinson's Disease "This has most likely been a life-saver. After numerous medications (trial and error) this allows me to live again."

10 / 10
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39 Report
  • dream
  • Taken for 1 to 2 years
  • June 2, 2014

Zelapar (selegiline) for Parkinson's Disease "This medicine remarkably helped my husbands shaking. He now barely shakes at all. Best Parkinson medicine we ever tried."

10 / 10
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27 Report
  • Z-Nine
  • Taken for less than 1 month
  • March 27, 2018

Emsam (selegiline) for Major Depressive Disorder "Is a potential cure for your depression worth crippling debt? Well I guess you'll find out after you pay over $1500 for a 30 day supply. Unless you have your Medicare paid for you, look elsewhere."

8 / 10
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18 Report
  • Anonymous
  • Taken for less than 1 month
  • July 2, 2012

Emsam (selegiline) for Depression "This is my first day on Emsam 9 mg. Very low blood pressure so far. Going to call doctor, in morning about that. Otherwise so far I have a little neck pain but nothing I can't handle."

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23 Report
  • Radio...
  • Taken for less than 1 month
  • November 9, 2019

Emsam (selegiline) for Major Depressive Disorder "Tried many antidepressant medicines over 30 years without much satisfaction now on 9 milligrams of ensam patch waiting to see results 1 3 weeks with a slight improvement in depression."

7 / 10
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8 Report
  • John...
  • Taken for less than 1 month
  • June 9, 2023

Zelapar (selegiline) "I found this antibiotic had side effects and interactions that were too scary. Avoid at all costs. try vancomycin instead. Try anything else instead."

1 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.