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S-adenosylmethionine for Osteoarthritis User Reviews

Brand names: SAMe, Natrol SAMe, Adomet

Rating: 6.7

S-adenosylmethionine has an average rating of 6.7 out of 10 from a total of 6 reviews for the off-label treatment of osteoarthritis. 67% of reviewers reported a positive experience, while 33% reported a negative experience.

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  • Chr...
  • Taken for 1 to 6 months
  • February 15, 2020

"I have never been blown away by a natural supplement like SAM-e. A year after major back surgery and a hip replacement, I was in more pain than before the surgeries, chronic debilitating pain. I researched SAM-e and decided to try it. Started with two 400 mg tablets a day and after a week, I felt like my pain was decreasing. I increased to three tablets a day and it's now been a month, and I'm a new man. SAM-e is remarkable. It not only works for joint pain, but also overall muscle and body pain, my mobility is returning to normal, a fabulous supplement :)"

10 / 10
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71 Report
  • Uki...
  • December 21, 2014

S-adenosylmethionine "I like SAMe. It keeps my mood even, and I have arthritis and anxiety. I have had pain remission ever since starting SAMe over 8 months ago. I take it with Super B Complex, which is recommended to keep homocysteine levels even. It works great as a mood elevator. Love it."

10 / 10
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115 Report
  • jas...
  • Taken for 1 to 6 months
  • June 1, 2021

"Used 1200 mg a day for a month. Had wild dreams starting week three. No noticeable arthritis relief. Reduced to 400 mg after week four. Still very bad dreams and no arthritis help. Stopped after six weeks."

1 / 10
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20 Report

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  • rox...
  • March 9, 2010

"During my treatment of depression and RA, it seemed all the medicines stopped working at the same time. I was taking Cymbalta. I tapered off of it and tried Pristiq, which worked horribly. I stopped taking them all and researched natural remedies for depression, and came across lithium orotate and SAMe. I have been taking both for a couple of months now, it seems to keep me level and out of the depressed state that I was in, so for now, it seems to be working."

8 / 10
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43 Report
  • Car...
  • Taken for 1 to 6 months
  • October 1, 2023

"I am a 75-year-old active woman. My doctor recommended I take 400 mg of SAMe daily for hip and leg pain. I have been taking it for 3 months, and it has worked wonders for me. I have very little pain now when I take my daily walks or garden, and I seem to have more energy. I don't have side effects from it, which I had when I took OTC pain medications, such as bad dreams and stomach upset."

10 / 10
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4 Report
  • Hey...
  • Taken for 1 to 6 months
  • April 30, 2015

S-adenosylmethionine "It works, but side effects with digestion are so bad. Had to stop it."

1 / 10
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57 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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