Phenergan and Restless Leg Syndrome: What Users Say

• Yol...
• Taken for 1 to 6 months
• December 28, 2021

For Sedation "I found half a 25mg tablet good for sleep. Can take hours before it starts working. The first time you take it, it works wonderfully. Be mindful it is an old antipsychotic and has a long half-life, so what that means is it builds up in your body. Always start on a low dose of 10mg and increase when needed. High doses can give you restless leg syndrome as it drops your dopamine level. It can also suppress breathing - not ideal! Best taken an hour before bed as its plasma peak is approx. 2 to 3 hours (the most effect) although that time level is dependent on your rate of metabolism. I am horrified reading how many people double the max recommended dose when they take the first time, not knowing how it affects you."

• Mar...
• Taken for 1 to 6 months
• October 15, 2021

For Sedation "I got these over 4-5 months. I started with 25 mg and ended up taking 2 every evening before bed. I started getting restless legs to the point where I had to wander around in my flat for hours like a zombie, and I sometimes only got a few hours of sleep. Also, I began to get a bloody nose. Every morning I had to clean my nose with tissues, and the paper was always bloody. And the weight gain. I gained 15 kilos in that time. Right before I quit taking them, I was miserable. Almost every night I had restless legs, and I didn’t get much sleep. I have been off Phenergan since the beginning of August - I lost 7.6 kilos, my nose is just fine, and I haven’t had one second with restless legs since. I’m back to having trouble falling asleep, but I definitely prefer that to all the horrible side effects."

• Jul...
• July 11, 2021

For Nausea/Vomiting "Second trimester of pregnancy and had lost 30 lbs due to hyperemesis. None of the other nausea meds were working, they even gave me suppositories. I was admitted to the hospital, and I ended up on an IV drip of Zofran for a couple of days to give me some relief. Once they took me off the drip, I was scheduled to get the Zofran regularly. One particular nurse was terrible about giving me my medication on time, and I got so sick they had to look for an alternative. She gave me Phenergan, which made me drowsy, uncoordinated, disoriented, and gave me restless leg for a while. That experience was terrifying. When the doctors came in to check on me, they told me that I was given too big of a dose, so they were going to try it again at half a dose. That half dose was AMAZING!!! It took away the nausea immediately and allowed me to sleep comfortably. That became my regular nausea med for the rest of the hyperemesis, and I was given a prescription to use at home as needed. It saved my life."

• Bri...
• Taken for 1 to 2 years
• March 8, 2022

For Light Sedation "Started taking this about a year ago. It worked okay, but gave me awful restless leg syndrome. Did not take it for a while, then started again. Worked okay for sleep, but I felt short-tempered and low mood. It is worth a try, as everyone reacts differently to it."