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Prochlorperazine User Reviews & Ratings (Page 2)

Brand names: Compro

Prochlorperazine has an average rating of 3.0 out of 10 from a total of 434 reviews on Drugs.com. 19% of reviewers reported a positive experience, while 74% reported a negative experience.

Reviews for Prochlorperazine

  • Anonymous
  • Taken for less than 1 month
  • December 4, 2018

Compazine (prochlorperazine) for Anxiety "Was given this medicine through an IV with a cocktail of other drugs to treat my headache because I got a concussion and was in the ER. Gave me a severe panic attack, I woke up crying and wailing around wanting to rip the IV out of my arm. I could not sleep, felt as if I was suffocating and could not breathe or get enough air. That night I went home I could not sleep without severe anxiety and my heart racing like crazy. Still felt as if I could not breathe. Woke up this morning and felt the same but not as severe. could not sit still and felt extremely restless or do anything normal and have been looking up to see if these symptoms are normal and am not surprised to see that many other people experience this too with compazine. I don't know when I will go back to normal but STAY AWAY FROM THIS DRUG."

1 / 10
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  • Itsya...
  • Taken for less than 1 month
  • January 5, 2020

For Nausea/Vomiting " I took this medication in a 5mg tablet for nausea and dizziness. Really worked - no nausea or dizziness and felt fine. Had a couple aches in my arms but meh beats feeling sick and dizzy. The medication did what it’s supposed to and this is coming from a hypochondriac himself who experiences side effects on almost everything. Take it, it might work for you."

10 / 10
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  • NuseN...
  • Taken for less than 1 month
  • July 17, 2020

For Anxiety "So.. I suffer real bad with anxiety. And I mean real bad. The smallest change/bad thought can set off horrific nausea and vomiting at any given moment. (I’m a Prison nurse so this doesn’t work well in my favour at all). The only thing that worked for me was “ prochlorperazine 3mg buccal tablets” prescribed by my GP. I CANNOT EXPRESS WHAT A BREATH OF FRESH AIR THESE ARE!!! My anxiety can last days/weeks at a time causing massive weight loss. Within an hour of taking these, my nausea vomiting and any anxious thoughts are gone. These may not work for everyone, but for me at 27 years old, I’ve finally found my medication!!!"

10 / 10
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  • MMano
  • February 18, 2019

Compazine (prochlorperazine) for Nausea/Vomiting "I went into the ER for a migraine. The nurse gave me a "cocktail" of meds: Toradol, Compazine & Benadryl. He told me my migraine should be gone within 15 minutes. BUT Within minutes of the Compazine being given to me through IV, I felt the worst I have ever felt. Agitated, restless, scared. It was the worst anxiety/panic I have felt. I wanted to die so bad. I NEEDED help and I kept calling out and they just told me "it'll wear off". I was hollering and crying and upset and absolutely terrified. I couldn't stop shaking, I wanted to rip my IV out and run out of there as fast as I could. It's been 2 weeks and I still don't feel like myself. I have these bursts of panic and nausea, I feel completely and utterly distraught. I told my doctor about it but they just dismissed me. I'm scared this feeling will never go away. It was completely traumatizing and I don't recommend this to anyone ever. I do not wish this on my worst enemy & you couldn't get me to take this again for a billion dollars."

1 / 10
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  • sadsa...
  • January 19, 2019

Compazine (prochlorperazine) for Nausea/Vomiting "Background info: I have a long medical history of generalized anxiety disorder & panic attacks. This medication caused THE WORST mental AND physical distress I’ve experienced in my entire life. I am not exaggerating; this was beyond any panic attack I’ve ever had, almost to the point that “panic” doesn’t suffice to explain what I felt. Every muscle in my body was tense & cramped, to the point that I wanted to crawl out of my skin. My stomach was clenched, & despite this being an anti-emetic, I felt like vomiting. I could not sit still or get comfortable, & ended up pacing like a lunatic for hours. I felt horribly self-conscious & emotionally distraught, & truly wished that these terrible feelings would end. PLEASE, stay far away from this medication!! Even if you’re not an anxious person, don’t risk it. I’ve been through some horrible things in my life, but the feelings that Compazine caused me are very near the top of the list."

1 / 10
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Are you taking this medicine?

  • Jessica
  • December 5, 2016

Compazine (prochlorperazine) for Anxiety "Went to the ER for a headache along with depression and was given compazine threw an IV an has been feeling detached from reality every since last year of november anybody else feels this way after taking this medicine and what do I need to do to get back to NORMAL all I do is cry and wonder why the doctors didnt warn me before taking this "

1 / 10
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  • Lou
  • Taken for 1 to 2 years
  • September 13, 2020

For Nausea/Vomiting "I was prescribed this prochlorperazine as I suffer migraines to the point of uncontrollable vomiting. Side effect from meningitis when I was 15 years old. I have ADHD/ Aspergers/ Social Anxiety. Ex party drug user too. No side effects except a dry mouth. I feel a lot of these comments talk about it being administered via IV which would hit your system like a catapult. No thanks. I took tablets and can’t say a bad thing. Nausea gone super quick, and overall I feel this drug works wonders but not if you’re not aware of your incoming anxiety/triggers etc. I know when my anxiety flares on and off medications. I had one moment of a mopey feeling but I recognised it and altered what I was doing so my thought process improved. Learn how your body works. Properly; and therefore most prescribed medications can work in your favour. Drs are drs for reasons. "

10 / 10
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  • Never...
  • Taken for less than 1 month
  • November 13, 2016

Compazine (prochlorperazine) for Nausea/Vomiting "They gave me this medication via IV in the ER for a very intense migraine and extreme nausea, I would never recommend this medication to anyone ever, the second it was pushed through, I started having an extreme panic attack, something like I have never felt before, like a huge wave of doom rushed over me, I started freaking out so badly I almost ripped my IV out and ran away, it was so traumatizing to me that they pushed a big dose of Ativan though my IV just to knock me out, I truly thought I was dying... And after all that it felt like my skin was crawling for a good 32 hours. No, thank you. Never again will allow this in my body."

1 / 10
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  • Ange
  • February 14, 2021

Compazine (prochlorperazine) for Nausea/Vomiting "I have migraine, vomiting, gallbladder issue's. I was asked if I wanted zofran or compazine. I asked little bit about side effects and the nurse said it's for migraines, vomiting, put in my IV 15 minutes later, like the room got dark, and i couldn't stay still. 30 mins later I called my mom crying telling her I'm dying there is no way I'm coming back from hospital. Many times I was about rip IV out pacing the hospital bed with IV cord on me. I felt the oncoming sense of doom, somewhat dismembered my IV on my arm, one point I was rip IV out, had no ride home hour away from home. I was going run outta the room in the streets zero below. I got a nurse in said yah the medicine can do that to people have reactions. Benadryl, reverse it it took 30 more mins for them to bring benadryl in, about 10 mins I finally dozed off. But I still couldn't stop moving walking around and nervous panic. I had got released, I had toget Benadryl from store keep it reversed for 24hrs. Worse dangerous drug. I will never take a unknown medication again."

1 / 10
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  • Iknow...
  • October 23, 2019

Compazine (prochlorperazine) for Anxiety "Everyone on here. I know exactly what you experienced it's a gruesome condition called akathisia.. and the doctors know about it. But they will not tell you!! It is a serious side effect. Because people can't stand the way they feel with akathisia. Please join akathisia group in Facebook. There is help and support if you're still suffering."

1 / 10
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  • Fiona
  • March 17, 2019

Compazine (prochlorperazine) for Nausea/Vomiting "I was prescribed this med in pill form for nausea from my chemotherapy as a backup in case Zofran did not work. Because Zofran caused me constipation I asked my care team if I could use the Compazine as the first defence. They said go ahead and try it. While taking this med I didn't want to sleep, didn't want to be awake, couldn't sit, couldn't stand or wait in line, had to pace back and forth to stop myself from doing something drastic. I snapped at loved ones because I was so desperate. I felt fear and dread and paranoia. At first I thought it was the chemotherapy I was on that was causing all these things but I finally figured out it was the Compazine. You snap out of the horrible side effects about 12 to 24 hours after taking your last dose. It feels like you are breaking a fever and finally feel more relaxed and relieved. I stopped taking it. Hoping this review will be helpful for those on chemo. Sometimes with all the drugs we take it's hard to pinpoint which one is the culprit."

2 / 10
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  • Carri...
  • May 11, 2013

Compazine (prochlorperazine) for Nausea/Vomiting "Compazine is chemically similar to Thorazine...both of which can cause extreme and sometimes dangerous reactions the in people who have risk of serotonin syndrome or sensitivities. I personally experienced rage reactions to Compazine when it was used to treat nausea from migraines. "

2 / 10
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  • Gabri...
  • July 16, 2017

Compazine (prochlorperazine) for Anxiety "Given this medication for a headache 3 weeks ago still feeling side effects! Very restless, insomnia,irrational thoughts, I feel like I've lost touch in reality! It's horrible! I wish they would've told me before they put it in me through IV! If anyone please knows what to do to fall back in to reality please share"

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  • Rita
  • February 29, 2020

Compazine (prochlorperazine) for Nausea/Vomiting "I was given Compazine IV in the ER ( which I work at the hospital ) for a severe migraine. Not much later after I started getting horrible sensations in my head. And creepy crawly all over. Couldn't communicate. Couldn't walk straight. And NO ONE noticed this !!!!! I was too sick to even realize it was the Compazine at the time. I had no idea it is in the THORAZINE family !!!!! Now I'm marked as having an allergy to COMPAZINE. NIGHTMARE !!!!!!"

1 / 10
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  • Dkb
  • Taken for less than 1 month
  • April 27, 2019

Compazine (prochlorperazine) for Anxiety "Went to the ER with a headache and was give an IV with Benadryl and compazine. IMMEDIATELY I began to have a panic attack. The only way I can describe it is like being buried alive. I was so tired but coming out of my skin. Worst feeling of my life and now going to the hospital and regular routine appointments give me anxiety. I’m afraid of getting shots and taking medicines. My life has not been the same since getting that IV. I don’t understand how this drug could be used to treat anxiety."

1 / 10
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  • blaze
  • Taken for 2 to 5 years
  • April 30, 2015

Compazine (prochlorperazine) for Nausea/Vomiting "I have been on Compazine for over 2 years and it has been an absolute overall relief of nausea, anxiety and nerves/nervous tension. Finding a doctor who will prescribe it without a struggle and or reservation is a whole other issue. I've been told it carries too many side effects and isn't considered safe or for long term. I've been told to switch to Zofran. The upside is Zofran seems to have a fairly good rating. I never suffered side effects from the Compazine."

9 / 10
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  • Shel
  • Taken for less than 1 month
  • April 2, 2019

Compazine (prochlorperazine) for Anxiety "This medication gave me the worst thoughts of suicide, fear and anxiety. My mother had to sleep with me for a week after so I wouldn’t cry due to being alone in my thoughts. This medication should be avoided AT ALL COST. REFUSE THIS MEDICATION"

1 / 10
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  • PA...
  • Taken for less than 1 month
  • May 31, 2014

Compazine (prochlorperazine) for Anxiety "This medication gave me the worst experience of my life. It made me sleepy, yes. But at the same time, It sped up my mental discomfort, and it made my muscles jump. Similar to restless leg syndrome, but throughout my entire body. It was so bad they had to reverse it with Benadryl to alleviate the symptoms, And finally they gave me a mixture of Valium and Demerol to put me in a twilight state until it passed. If you have ANY medication allergies, even mild. I would strongly advise against this medication. "

1 / 10
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  • AJO
  • Taken for less than 1 month
  • December 10, 2019

Compazine (prochlorperazine) for Nausea/Vomiting "Y’all, my experience was exactly like so many others. I was having dizzy spells for over a week and then suddenly had the worlds worst headache so I went in. They gave me toradol and compazine through an IV and within ten minutes, I thought I was going insane. I asked to go to the bathroom just to get out of the room. I couldn’t sit still and felt so panicked. On my way back from the bathroom, I seriously considered ripping out my IV. When the nurse came in, I stopped my fluids, and went home. Had to sign a paper that I was refusing treatment, but I couldn’t be in that room any longer."

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  • JMG
  • March 23, 2017

Compazine (prochlorperazine) for Nausea/Vomiting "My wife was administered Compazine after receiving chemo to relieve nausea symptoms. Within 12 hours, she became restless, irritable, felt like her muscles were being ripped out of her body, it caused her to have a 103 fever and diarrhea, coupled with the chemo almost killed her. She ended up in the ICU unconscious and almost died. Our team of doctors told us the was a rare occurrence. From reading the other reviews, and witnessing this first-had. I would advise anyone, if offered this drug to decline. It was truly the biggest nightmare of my wife's life. On the scale of 1-10 above this survey asked to select how effective this medicine was. Therefor we would give it a 0=ZERO."

1 / 10
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  • Anonymous
  • August 27, 2018

Compazine (prochlorperazine) for Nausea/Vomiting "I went to the ER with a migraine and nausea/vomiting. I saw the doctor and then the nurse brought a medication into my room, Compazine. Then they wheeled me over to get a CT scan. That’s when things went all bad. Sitting there, in the hallway on the gurney I began having this overwhelming feeling of anxiety/panic! The problem was, my body felt like I couldn’t move, like there was a disconnect from my mind and my body. After the CT scan I was back in the room. All I could think about was when I can get out of that ED and when those feelings of anxiety would stop! It was literally, the worst feeling in the world, so hard to describe, but I have never felt so uncomfortable and anxious, yet unable to do anything about it. I wanted to rip out my IV and run out of the ASAP! It took an entire 3 DAYS before I started to feel “normal” again! It was torture. Worst experience. Never, ever take Compazine if you can avoid it. I now have Compazine listed as an allergy."

1 / 10
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  • cruise
  • April 22, 2019

Compazine (prochlorperazine) for Anxiety "I was given Compazine in the hospital along with Toradol. I have been to ER many many times for migraines and they wouldn't listen to me, I usually get Toradol and a just a tiny bit of morphine. The doctor said no and gave me this combo. That was two years ago and ever since I have had to be on multiple medications from the severe side effects I had. I ran out of the hospital, complete panic stricken, horrible thoughts, dread, doom you name it. I am not taking several pills a day all because of one single dose of Compazine. I can not get any lawyers that will handle my case because its against the drug company. Awful awful drug."

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  • Scott...
  • Taken for less than 1 month
  • October 26, 2018

Compazine (prochlorperazine) for Anxiety "I went in to ER for a migraine and was given this. Immediately a rash developed on my arm and I felt like I was going crazy! I felt as if someone was trying to kill me and I had to get out of that room! I NEVER had anxiety in my life. Didn’t realize that is what caused it until my 2nd ER visit months later the same thing happened. Did some research and spoke to my Dr and was told it was the compazine! It is now listed as an allergy in my chart. I felt like I was full blown psychotic! Lasted for a couple of days until I felt normal again. This med should be recalled!"

1 / 10
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  • NelBe...
  • Taken for less than 1 month
  • March 25, 2017

Compazine (prochlorperazine) for Nausea/Vomiting "I was in and out of the ER due to migraines and on the last day they gave me a prescription of Compazine. The next day when I took it I laid down to take a nap and woke up struggling to breath. My throat was closing and I could barely talk. I went into a full blown panic attack and called the ambulance. They gave me 3 different shots of something I can't remember and rushed me to the hospital. My jaw felt locked like I clinching my teeth hard together by the time I got to the hospital. I was shaking uncontrollably and crying hysterically. After I was discharged I came home and chugged some childrens benadryl and took some xanax and felt the side effect slowly go away. I have never in my felt so scared."

1 / 10
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  • PBano
  • Taken for 1 to 6 months
  • December 13, 2019

Compazine (prochlorperazine) "I went to the ER twice for a migraine and received Compazine, Toradol and Benadryl via IV. Both times I felt like my body was not my own. I instantly felt jittery and couldn’t sit still. I wanted to jump out of my skin. All I wanted was to go home. The cocktail worked, but when I was finally released I could barely drive home because I couldn’t sit still for more than a few seconds. I had to pull over multiple times. I called the ER when I got home because I couldn’t sleep at all. The nurse told me to take another dose of Benadryl and it should subside. It took 2 days to get back to normal. I thought it was the combination of the Compazine, Toradol and Benadryl that caused this side effect until I was admitted to Johns Hopkins for DHE treatment. They gave me Compazine before the start of the treatment and I immediately felt crazy. All the symptoms I felt in the ER happened again. The worst medication I have ever received. Count yourself lucky if you didn’t experience this."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.