Plecanatide User Reviews & Ratings (Page 3)

• Car...
• Taken for less than 1 month
• August 9, 2018

For Chronic Idiopathic Constipation "Those of you saying it caused stomach pain, bloating, and didn't produce a BM should probably make sure that 1. You don't have a blockage and 2. Be tested for pelvic floor dysfunction or possible anal stenosis."

• Wil...
• August 28, 2017

For Chronic Idiopathic Constipation "I was taking Linzess for the better part of three years, it did the job but had major AEs. I experienced bloating, weight gain, and the biggest problem for me was stomach pains. My GI doc switched me over to Trulance about 30 days ago, and as of now, I'm not having any AEs. I hope it continues to work this well."

• BBW...
• Taken for less than 1 month
• November 1, 2019

For Chronic Idiopathic Constipation "I’m a female in my late 30s that has experienced severe constipation since pregnancy 6 years ago. This drug has caused nothing but dehydration, bloating, congestion, and weight gain. I will not continue use of this drug."

• Ken...
• June 1, 2017

For Chronic Idiopathic Constipation "Trulance is working great so far. Doctor says to continue it for 90 days. My BM is better and consistent. I hope I don't have to take it for life, but so far it works just great without evil side effects of Linzess."

• Ms...
• June 5, 2019

For Irritable Bowel Syndrome with Constipation "So I’ve been taking Trulance for almost a year now. The lowest dose (3 mg), I believe. I went to a GI doctor because I was having stomach pain. I had an endoscopy and colonoscopy done, and everything looked good, minus some gastritis and a really loopy colon. I ended up having a robotic pyeloplasty due to a UPJ (ureteropelvic junction obstruction). She put me on Trulance to help me have good BMs. I take one pill 30 minutes before breakfast. And then I have to stay by a toilet for at least an hour. Explosive, runny, and loud Hershey squirts. So I guess it does make me go... even though it was actually my kidney that was causing the stomach pain. The doctor said my colon is loopy and I’ll have problems if I don’t take something. My real complaint is the weight gain. I would say probably 10 to 15 pounds in almost a year. Thinking about switching or seeing if I can get off the meds altogether. Hope this helps. God bless and good luck!!"

• IBD...
• Taken for 1 to 6 months
• January 23, 2020

For Irritable Bowel Syndrome with Constipation "I was diagnosed with IBD a year ago after a year of tests and changing to a new GI doc. I was placed on a low dose of Linzess 12/2018, but because I was in the bathroom for many hours, I only took it during the week or if I was home (I work at home, so that helps). I would not take it on weekends or any day I was off or on vacation. I would take it at 5:15 am and knew by 7:15 am the medication would take effect. By the afternoon, I was able to go out. My doc changed me to Trulance this December, hoping that this medication would have a different effect. It does not. I do the same routine with this medication. During the times that I did not take Linzess or do not take Trulance, I take a 6-ounce glass of prune juice and 2-3 medjool dates from Costco at night. Sometimes I warm the juice. This remedy usually helps me. I am hoping at some point to get off any medication."

• Yai...
• Taken for less than 1 month
• May 26, 2021

For Chronic Idiopathic Constipation "Works well. However, my prescription Part D coverage insurer doesn't cover it. $500.00/mo. is a bit steep. That's $6000.00/yr. just so you can have a bowel motion. The pharmaceutical companies are only interested in the dollars."

• Blu...
• Taken for less than 1 month
• July 25, 2020

For Irritable Bowel Syndrome with Constipation "The doctor gave me samples of this after Linzess made me constantly bloated (I looked pregnant) and gave me nothing but diarrhea. Trulance does the same to me when it comes to diarrhea, and it seems a bit worse at times, like having to stay on the toilet for 2 hours. Sometimes it doesn't work as great, and I feel horribly bloated on my left side until I wake up the next day. One good thing is that I'm not constantly bloated anymore, but the diarrhea is a letdown because I need to be able to leave the house. It's been 3 weeks on this medication, and I'm not sure if I'm really liking it much, I'm not sure what the doctor will suggest next."

• Hay...
• Taken for less than 1 month
• June 24, 2018

For Chronic Idiopathic Constipation "I love Trulance! I’m surprised people are saying it made them gain weight, as it is not a listed side effect, and I actually managed to lose 2 lbs while taking it. I’ve suffered from severe bloating and moderate constipation for almost two years. I was sick of the constant cycle of laxative on Friday night - flat stomach Saturday - constipation building Sunday through Friday - repeat. I was tired of planning my life around my laxative and my bloat. There were and are many times when I take a laxative and it would do nothing but make me bloat up to two sizes bigger than I am. Trulance has been gentle. No cramping, only mild bloat, and no water retention. My only negative comments revolve around the day-long diarrhea and the stomach distension that comes from going off it cold turkey. (I ran out and am waiting for my prescription)"

• BRa...
• Taken for less than 1 month
• December 24, 2019

For Irritable Bowel Syndrome with Constipation "I hadn't gone in 5 days when my insurance finally approved Trulance. My doctor had prescribed Linzess, but the insurance company denied it. They wanted me to try Trulance first. (My longest was 8 days without a BM, and I ended up in the ER for bleeding after straining.) I took the pill shortly after I picked it up from the pharmacy. Within 1 hour, I had explosive diarrhea.... yes, I felt relief but not better. The side effects are too much... headaches (and yes, I drink tons of water), lack of energy (I am usually bouncing off the walls), and the fast weight gain (4 lbs in two days)! I also experienced no bowel movement when I took the second, third, and fourth dose. Horrible indigestion and just a flu-like feeling. I hope one day I can find relief, but for now, I think I will go back to laxatives and stool softeners."

• jen...
• Taken for 1 to 6 months
• October 27, 2018

For Irritable Bowel Syndrome with Constipation "Trulance is a lifesaver for me! I used to suffer a lot because of my stomach, now I take Trulance every morning, go to the toilet about an hour later, and for the rest of the day, I'm free from thinking about it. I don't get anxiety anymore because of this condition."

• Jul...
• Taken for less than 1 month
• August 31, 2018

For Chronic Idiopathic Constipation "I was so excited to take this. I took one on my way home from the doctor, as I hadn't gone in 2 weeks! So I went out to eat, and an hour after I took it, I ran to the bathroom-explosive diarrhea for 3-4 hours to the point I couldn’t make it to the bathroom. So the next time, I decided to take it at night, and an hour after, my stomach gurgled loudly for 2 hours, then back to explosive diarrhea for 3-4 hours, the kind you don’t even know is coming! Wish it would work for me, but I would rather be constipated at this point!"

• Mar...
• Taken for 1 to 6 months
• August 6, 2023

For Chronic Idiopathic Constipation "I've been on the drug for a month. I feel great. It has saved my life of misery. I just started my second month. I pray I continue to do so well. I've only had a few bouts of diarrhea in the beginning as my body was cleansing itself of old stool which always made me sick inside. I am so much better, I hope it continues."

• Eur...
• Taken for 1 to 6 months
• February 17, 2018

For Chronic Idiopathic Constipation "I take 3 mg at bedtime for my gastroparesis. I wake up each morning with a comfortable, normal BM. At week two, I experienced some bloating, but it subsided within a week. I have never had anything work this well. My choices have always been severe, painful constipation or highly medicated, cramp-inducing diarrhea. Trulance has changed my life after years of too much time spent and thought spent on my bowel management."

• Rel...
• Taken for 1 to 2 years
• February 14, 2023

For Chronic Idiopathic Constipation "Update on my review below. Been taking this for about a year now, and it's a mixed bag of the sacrifice of time to take it vs. the relief. I have been taking 1/2 a pill now every day. I would say you get an hour before you need to go. Working from home, I would say it's a good 4 trips to the toilet in those first 2 hours, and if I need to actually do something and have a life during the day, I will finish the process with a Fleet Liquid Glycerin suppository to clear out the rest, and then I'm good for the rest of the day. My new marketplace plan has this costing me $25 for 90 pills, and I almost fainted at the pharmacy because it was $150 for 30 pills on my old plan. Trulance basically liquefies whatever is in your intestines and gets it out with no straining. It's perfect for anyone who has pelvic floor issues and can't do the pushing to poop. If you have the time to deal with it, this drug is a life-changer."

• lin...
• Taken for less than 1 month
• December 20, 2020

For Chronic Idiopathic Constipation "Second day on Trulance, both days I took half a pill. Just to be sure I'd go, I had taken 2 sennas the night before. Today's result was watery as if I'd taken mag. citrate. For me, this is pretty powerful. I think it'd be best if they would give a 1 mg tablet. No doubt I can stop the senna now. I wanted to because over time you need more and more of senna (for me anyway). So now I'll skip the senna (was on 4-5 pills) and try half the pill. If that works, I'll try 1/4 or 1/3. I can see why headaches are an issue sometimes...losing a lot of water. So drinking up!"

• Cyn...
• Taken for less than 1 month
• December 16, 2019

For Chronic Idiopathic Constipation "My husband has chronic constipation since I met him, 33 years ago. The doctor gave him Trulance 4 days ago as a sample, and it works, but he is so tense and reacts instantly to any kind of stimulus... dropped a book, big freak out. If a minor problem arises, it's a huge deal. He slams car doors, complains about everything, is really on edge. This drug must be responsible. Not like this before. Anyone else?"

• Fre...
• Taken for less than 1 month
• November 27, 2020

For Irritable Bowel Syndrome with Constipation "Trulance works great with me, and I love the medication. A real lifesaver. Ammonia did not work, and Linzess gave me constant heart flutters. I typically have a bowel movement within 1-3 hours. Sometimes very wet stools, sometimes not. The first day I took the medication, I had extreme pain with bowel movements overnight. I only had a fraction of the pain the next day I took it, and now I am painless."

• Sun...
• Taken for less than 1 month
• September 16, 2018

For Chronic Idiopathic Constipation "I'm sick as a dog as I type this. I feel beat up and sore with terrible spasms after being on the commode all night. I feel really bad because my doctor really wanted this to work for me and fought so hard with my insurance company to get Trulance approved. He wanted me off of Lactulose, but I cannot go back to that due to the same symptoms I'm having now. IBS has ruled my life for so long, and I eat so healthy and exercise, but I just cannot 'go.' I live a life of constant pain and spasms...."

• For...
• Taken for less than 1 month
• September 25, 2019

For Chronic Idiopathic Constipation "Doctor gave me samples of Trulance 3 mg to try. Took it for 6 days, feeling nervous because side effects include diarrhea. Nothing, I mean nothing, even with a little help (suppository & enema). Felt so bad that I had to take that vile citrus of magnesia to get some relief. It may work for you, but did nothing for me."

• hom...
• Taken for less than 1 month
• April 11, 2018

For Irritable Bowel Syndrome with Constipation "I have had irritable bowel syndrome with constipation (IBS-C) for most of my life. I am a 56-year-old man. I have had other problems since my early thirties, which are side effects from eating and drinking anything that contains sugar. If I eat ketchup on fries, drink a soda, or a glass of sweet tea, I am unable to keep my eyes open after 30 minutes and have to sleep off the symptoms. I started taking Trulance last Friday. I have had a BM every day since then. I no longer have side effects to sugar. I love this medicine!"

• bee...
• Taken for less than 1 month
• September 24, 2019

For Chronic Idiopathic Constipation "I've been constipated all my life - since I was an infant. I've gone up the chain of laxatives, and Trulance is my most recent medication. I took it with my evening meal, and it worked in an hour, which surprised me. I made six to eight trips to the bathroom before the excitement ended. I then noticed burning in my mouth and down my esophagus to the end of my rectum. Then my muscles started to ache. It all reminded me of a mobile sweeper that went through my gut and even in the most remote crevices to remove stool. I was exhausted. The following day I thought I was fine, and then suddenly I felt incredibly weak and unwell. I noticed slight swelling in my fingers - drank water. I want to give this a chance, but if I start swelling up or gaining weight, I will have to look at another solution."

• HJB...
• Taken for less than 1 month
• September 22, 2018

For Chronic Idiopathic Constipation "I have had idiopathic chronic constipation for about 2 years now. Nothing over the counter ever worked for any more than a few days or so. Only a few times over the past two years or so, I've got to the point of feeling relief when I was forced to take a colon cleanse such as GoLytely due to not going for 2 weeks at a time. My doctor has prescribed me Relistor, Linzess, and now Trulance. Relistor and Linzess, just like every other medication I tried, lasted for a few days of small bowel movements, then slowly stopped working at all. I took Trulance for the first time this morning - I have had normal to medium bowel movements since taking it over 12 hours ago. Mild cramps that come and go, mild dizziness as I get with all constipation meds, but overall can't complain at the end of my first day. Hoping this drug continues to work and clears me out as I constantly am backed up for weeks, and I am sure I have about 30 more trips to the bathroom left before I am completely empty."

• Pun...
• Taken for 1 to 6 months
• September 18, 2018

For Chronic Idiopathic Constipation "I take it twice a week. Usually works within an hour and have relatively normal BM unless I am backed up. Then I get the diarrhea everyone complains about. Have to make sure you have fiber when taking, and that seems to help decrease the bloating."

• Nit...
• Taken for less than 1 month
• May 1, 2019

For Irritable Bowel Syndrome with Constipation "I’ve been suffering from IBS-C since 2009. Sometimes it’s so severe that I get stressed something more serious is going on. After 3 colonoscopies, a CT scan, and taking Amitiza and Linzess, I was prescribed Trulance along with Dicyclomine (for discomfort/pain) and IBGuard (by my 3rd gastro). I’ve been taking it for 3 weeks, and I’m finally feeling better. I can even have a few consecutive days at a time without any pain at all. I’ve also been sticking to eating FODMAP-free since 2015. It never worked before while on the other meds, but everything seems to be working together now. I’m so much happier and more comfortable in my clothes, when I go out, and in the bathroom than I was prior to Trulance. The only discomfort I’ve had while on it is acid reflux. However, I’m not sure if it's due to Trulance or the other meds I’m taking now. Good luck to others taking it!"