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Phenelzine User Reviews & Ratings (Page 3)

Brand names: Nardil

Phenelzine has an average rating of 8.5 out of 10 from a total of 140 reviews on Drugs.com. 78% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Phenelzine

  • Whale
  • Taken for 6 months to 1 year
  • October 28, 2018

Nardil (phenelzine) for Depression "I experience social anxiety, extreme introvert. Nardil helped me to talk easily with anyone about anything. It eased my self-consciousness and helped me with anxiety. It did cause me to have an insatiable appetite for sweets, especially ice cream so the weight gain was tremendous. I wish I could go back on it again but don't want to go through the whole psychiatric scene again so I deal with social anxiety."

8 / 10
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  • Lou
  • Taken for 10 years or more
  • November 28, 2019

Nardil (phenelzine) for Depression "Like others on this forum had to go “cold turkey “ with literally 5 tablets left when I was told they were unavailable. GP told to cut remaining tablets in half. Went from 45mg a day to 7mg a day. For the last 4 weeks been on no tablets. I am sleeping very well. My mood is ok. Finding it hard sometimes to motivate myself to do stuff at home but still working. The worst thing is the nausea! My real concern that my mood has not dropped significantly. Does this mean that having taken this drug for 17 years that the chemicals are still in my body long after the recommended “washout” period. Haven’t eaten any banned foods. Bit scared to try. Would really appreciate any advice from anyone who has come off Nardil after years of taking it. Or any pharmacists who can help."

10 / 10
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  • Jlano
  • Taken for 10 years or more
  • March 17, 2018

Nardil (phenelzine) for Depression "I have been taking nardil over 30yrs. It was a new lease on life no other antidepressants worked for me.the only,side effect,is weight gain.my doctor has lowered my dosage over the years from 15mg three times a day to two times a day. Watch out for hypotension, when first starting nardil and follow dietary restrictions. The only issue I had was the formulation was changed about 12 years ago, and new formulary does not work as well. I wish I could locate the old formulation."

9 / 10
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Frequently asked questions

  • Connie
  • Taken for 5 to 10 years
  • January 10, 2020

Nardil (phenelzine) for Depression "On nardil 7 years, went to get my refill they said it was on backorder. I had no choice but to go without, it's been over a week and I'm having terrible withdrawals. Feel nauseated, headache, zapping in my head and tired. I'm so disappointed in my pharmacy, they knew I was out and didn't offer any help or advice. Now I am suffering and my mood is dropping more and more."

6 / 10
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  • Mothe...
  • Taken for 10 years or more
  • March 2, 2020

Nardil (phenelzine) for Depression "I am in the same position as the other people posting reviews in that I am worried to death about the shortage of Nardil both in the Uk and Canada. I would just like to mention to the people who have posted on here that there is a support forum on this site for Nardil/Phenelzine where it’s possible to chat to each other about our concerns maybe have a look and see what you think Motherbaggins"

10 / 10
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Are you taking this medicine?

  • xzard...
  • Taken for 2 to 5 years
  • July 29, 2017

Nardil (phenelzine) for Depression "I took nardil for 4 years. It changed my personality drastically. I went from depressed and withdrawn to hypomanic (which is like half way to fully manic). Much more sociable and I also became a workaholic. The side effects were intolerable - extreme weight gain (gained 50 lbs which brought me over 200 lbs. had never been overweight before or since) and anorgasmia. I did prefer hypomania to unipolar depression but eventually I pooped out on it as everyone seems to do in these designer ADs within a few years. There was a study which found that MAOIs like Nardil can permanently damage your mu receptors preventing you from having the capability to experience euphoria and that happened to me also. I wish I never taken any of those drugs."

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  • Misha
  • May 16, 2018

Nardil (phenelzine) "Started on phenelzine (Nardil) in the 1980's. It saved me from the bleakness of depression mixed with anxiety. Two things: the young psychiatrist who first prescribed it told me most of his patients did not have to heed the dietary restrictions. Suggested that if I wanted I could try one ounce of any food/beverage on the list, then wait one half hour. If after that time I developed a (mild) headache at the base of my skull, I’d have to avoid item. Turns out I can eat or drink whatever I want. (I've read current information that shows the dietary restrictions have been exaggerated.) Secondly: Despite warnings that once you stop taking it, phenelzine will not prove effective should you begin taking it again in the future...I have gone for extended periods where I have NOT taken phenelzine, with no loss of effectiveness when I began taking it again. True for me, at least."

9 / 10
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  • Bipolar
  • Taken for 1 to 6 months
  • March 8, 2015

Nardil (phenelzine) for Depression "Nardil works very well for my bipolar depression. I had hypersomnia when I was depressed and the drugs I tried (Lamictal, Zoloft, Celexa…) didn’t help at all. I’m glad my psychiatrist made me try this medication. At first, I took 45 mg, but after a while, it made me maniac. I had to lower the dosage to 30 mg and, surprisingly, it’s seems to be working (even though it’s not considered as a therapeutic dose). The diet is very easy to follow, as long as you can take bottled beer. The only downside is the sugar cravings, which are difficult to resist."

9 / 10
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  • GauGreg
  • Taken for 1 to 6 months
  • November 24, 2017

Nardil (phenelzine) for Depression "I had been on this in 1982 for years , (it worked , but then no one wanted to prescribe it) . After many different SSRI combos and add ons ,and finally Bupropion , and even TMS nothing. Went back on 75mg of Nardil my whole attitude has changed, everyone at work has noticed. This should be treated as a drug of last resort though. There are over a 1000 drug interactions, not to mention the food issues"

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  • Anonymous
  • October 14, 2008

Nardil (phenelzine) for Depression "I suffered from prolonged depression for most of my adult life with no relief until Nardil was introduced to me. I have been taking a daily dosage of Nardil for over 10 years and it has helped me enormously."

8 / 10
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  • andrew
  • Taken for 6 months to 1 year
  • November 2, 2013

Nardil (phenelzine) for Depression "I am still on Nardil and waiting to wean off. My experience has not been great. It hasn't helped me with depression as it only has causes terrible adverse effects that has affected my life. I am depressed, angry, irritated, anxiety-ridden, just to name a few symptoms. My doctor is going to start getting me off it soon as he will try Nortripyline. It's true that Nardil works for a lot of people but not me. Just a terrible experience."

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  • Navyman
  • Taken for 2 to 5 years
  • August 13, 2016

Nardil (phenelzine) for Depression "Tried so many anti depressants from 1982 to present then finally looked up Nardil and asked my provider to please please try it as i am tired of going back and forth on the Old and the new medications. Started the titrade from 25 mg daily and up to 45mg twice daily with such a relief from years of depression and anxiety after diagnosed with PTSD. Felt best at the 90mg daily but now i notice the feeling is fading and I am wondering if the new batches are No good. I speak of food for myself as i eat anything that i want and have not experienced any negative feeling. Weight gain is a real negative especially in my gut and i can seem to get rid of it."

9 / 10
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  • Annali
  • Taken for less than 1 month
  • September 16, 2018

Nardil (phenelzine) for Depression "Took away my panic attacks, but gave me depression, severe agitation, and a racing heart. I may have been a bad candidate for this drug since I'm pretty high strung. At 45 mg, I experienced insomnia like never before-- no sleep for 5 days straight! Every time I would not off, I would get jerked wide awake. I was scared I was never going to sleep again. I don't recommend this if you are med sensitive. Withdrawals are a whole different story, way worse than any ssri or snri. Please be careful with this drug."

2 / 10
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  • Jettr...
  • Taken for 1 to 6 months
  • August 27, 2020

Nardil (phenelzine) for Depression "I have battled PDD/MDD my entire life and things came to a severe head about 10 years ago when I had a major breakdown that lasted all this time. I was put on over 20+ different meds including every antidepressant you could think of. I did the research and convinced my doctor to try MAOI's and he put my on Nardil. It has been a few months now and the change is amazing. My wife even sees and it says I am totally a different person. The only area I am still having issues with is motivation but have a call in to the doctor to discuss. I am on a combo of Nardil with Lamictal as a mood stabilizer and I couldn't ask for more."

10 / 10
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  • Bamae...
  • August 28, 2009

Nardil (phenelzine) for Depression "My psychiatrist utilized every combination you can think of and finally Nardil. While I am very careful about foods and wear a medic alert bracelet and carry an alert in my purse that NO Demerol can be given as it can cause death, I finally feel better from a deep depressive state since October 2008. My memory state however has not improved but my physical state has and I can at least get out of bed and be somewhat sociable with friends and family. I have had a very positive experience with it so far."

10 / 10
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  • Dete
  • Taken for 1 to 6 months
  • August 8, 2019

Nardil (phenelzine) for Depression "I’m in tears today. I’ve been told I have to stop Nardil as they are out of stock in whole of UK for at least 3 months. I'm doing far far better far better on these. Without this stuff I’m basically in bed everyday with clinical depression sometimes for years. My care co ordinator has been ignorant as has my consultant refusing to get on the phone and telling me to cold turkey.! See me in a month. The NHS are advising if you need it it is available from My life is over."

8 / 10
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  • matth...
  • Taken for 1 to 6 months
  • June 17, 2021

Nardil (phenelzine) for Depression "It’s encouraging to know that some people are on this med for years and seem to be doing well, it’s also hard to believe because I had a horrendous experience. What’s your daily dose? I was started on 15mg daily and increased to 15mg 3x daily. After 9 weeks I developed psychosis, manic, hypomanic reactions and had to be hospitalized. This was considered a rare side effect but it happened to me. Have any other people become psychotic with Nardil or MAOI’s?"

1 / 10
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  • Anonymous
  • December 30, 2008

Nardil (phenelzine) for Depression "I began taking Nardil and Ativan after my psychiatrist had tried many other antidepressants. I only became more anxious and panic-prone. Gradually my "conditioned response panic attacks" began to decrease in frequency. I began to have confidence that the medication and my own awareness of my body's response to certain situations could be controlled. I have gained weight, but I have lived a near-normal life."

8 / 10
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  • kwsilva
  • April 5, 2009

Nardil (phenelzine) for Depression "I think I was depressed when I was born. Had tried many antidepressants, but none worked even half as well as Nardil. I was on Nardil for 20 years until I was forced to come off of it by a psychiatrist, and cold turkey at that. That's been almost 2 years ago and I've not been the same since."

10 / 10
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  • Linmeme
  • Taken for 10 years or more
  • October 1, 2019

Nardil (phenelzine) for Depression "Suffered agoraphobia anxiety and depression but Nardil has been my life saver and I’ve done things I’d never thought I could, flying abroad etc. I had to stop almost cold turkey as couldn’t get tabs been awful!! Depressed, nausea feeling sweats heart racing. After a month managed to get tablets from pharmacy that delivers to door, 1 week on 15mg now 2nd day on 30mg NEVER take more than that. Still suffering bouts of tears, tiredness and loss of appetite. Lost 10lb since stopping. GOT TO THINK POSITIVE AS I KNOW THEY WORK!!!"

10 / 10
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  • Gigi
  • Taken for 10 years or more
  • November 3, 2019

Nardil (phenelzine) for Depression "After hospitalization for depression and 14 months on just about everything without success, my doctor suggested we try Nardil. I’ve lived on it very well for 22 years. I recently tried a newer antidepressant on the market named Trintellix. I had awful side effects and lost 14 of my 132 lbs within an 8 week period. I couldn’t even get to the 20mg therapeutic dose due to side effects. Started to decrease dose to go back on Nardil, which required taking nothing for 2 weeks. I got suicidal and ended up in the hospital. Started Nardil 5 days ago and am already feeling better. Not where I was before I got off, but hopeful I’ll soon get my life back. I just hope it restores my appetite! I’d prefer to be on a “safer” drug but considering I lived a decent life for 22 years on Nardil vs 2 1/2 months of hell while off, I’m glad to be back on. If you’ve tried other antidepressants without success, I recommend you give it a try"

10 / 10
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  • Rach
  • Taken for 6 months to 1 year
  • March 29, 2023

Nardil (phenelzine) for Depression "1000x better than any SSRI or SNRI on the market. For truly treatment resistant depression characterized by melancholia and anhedonia, this medication is life changing. Side effects are tough in the beginning but ease up over time."

8 / 10
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  • Jim
  • Taken for 6 months to 1 year
  • December 30, 2020

Nardil (phenelzine) for Depression "I think Nardil is the best antidepressant. I have tried at least a dozen drugs (SSRI, SNRI, Mirtazapine, Tryciclics) Only Nardil produced a response for my depression, anxiety and panic disorder. If you have any of these mental health conditions, do yourself a favour, and get on Nardil if you really want a recovery!"

10 / 10
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  • Noah
  • Taken for 1 to 2 years
  • July 28, 2023

Nardil (phenelzine) "Severe social anxiety and treatment-resistant depression had become constant companions in my life, overshadowing any sense of joy or fulfillment. Despite years of trying different medications and therapies, I felt like I was stuck in a never-ending cycle of despair. That was until I discovered Nardil. From the moment I started taking it, I noticed a significant shift in my social anxiety. The racing thoughts and paralyzing fear began to subside, allowing me to engage in social situations with greater confidence and ease. Nardil gave me the ability to navigate social interactions without the constant worry of being judged or rejected. Nardil also proved to be a game-changer in my battle against treatment-resistant depression. It lifted the heavy fog of sadness and despair, replacing it with a renewed sense of hope and optimism. Nardil has truly been a lifeline for me."

10 / 10
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  • annlit
  • Taken for 10 years or more
  • May 19, 2023

Nardil (phenelzine) for Depression "Nearly 60 years ago I was given this last resort antidepressant. I had been given various RXs, hospitalized, and given electroconvulsive “treatments” by my doctor. I was not given anesthesia. Without further elaboration, Nardil was life-changing. It must not be discontinued."

10 / 10
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7 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.