Pazopanib User Reviews & Ratings (Page 2)

• Grandma...
• March 10, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "I am 70, female. 19 years ago had right kidney removed due to renal cell cancer. In spring of 2016 my shoulder began to bother me, and it got worse until my upper arm broke just below the shoulder, due to renal cell cancer which had metastized to my upper arm bone, my pancreas tail, and two spots on my liver. I first had two weeks of IL-2 which gave me awful side effects and no changes to the cancer tumors. Have been on Votrient since September 2015. November scan shows tumors shrinking. Feb 2017 shows tumors are still shrinking. Side effects are diarrhea every day, body and muscle pain, scaly sores on my bottom, fatigue, and just recently pain in my hands. I take 800 mg daily, late in the day. I take Tramadol for the body pain."

• chada...
• Taken for 1 to 6 months
• May 2, 2016

Votrient (pazopanib) for Renal Cell Carcinoma "Lost my first kidney 5 years ago two months ago cancer was found in my remaining kidney. It had metastasized to my brain and lungs. Had gamma knife surgery on brain tumor. Started votrient about 1 month ago. Side effects include fatigue and high blood pressure.So far doing well on 800 milligrams. Have lost about 45 pounds I know now I need to eat regular meals in order to keep up my strength. This also helps with the fatigue. So far lab work looks good looking for the best results with votrient"

• Conni...
• January 24, 2013

Votrient (pazopanib) for Soft Tissue Sarcoma "I started taking it about 6 weeks ago for sarcoma. The only trouble I have had with it has been some gastro discomfort. But I was taking it first thing in the morning on a totally empty stomach. Now I eat breakfast and take it two hours later. Then eat some yogurt an hour later and so far all the stomach pain is gone. I do have some food allergies and a slight case of irritable bowel syndrome so I was not really surprised when I had the stomach pain. I have a CT 2/13/13 to see if the tumors are continuing to stay shrunk. But I feel fine. "

• jani
• March 1, 2016

Votrient (pazopanib) for Soft Tissue Sarcoma "I'm 39 years old guy from sweden, I have soft tissue sarcoma in my stomach wall and it spread to the bones (legs both femural head and sternum and my headscull that was removed) I have started votrient 201508 800mg/day. The first 2 weeks I had a fever and felt really sick, stomach problems pain and diarrhea, it took about 1-2 months before I felt normal with this med, the pain from my bone mets disappeard pretty fast (1month), I have had new scans after 3 months and the results was pretty good, sternum and right leg was nothing left :) the left leg there is only about 30% left. I'm going to have new scans this month so lets see hoping for more good news.... the stomach tumour was the same"

• elwood
• November 17, 2014

Votrient (pazopanib) for Soft Tissue Sarcoma "Wife is on this now for her 4th week (800mg ) she has Soft tissue in Right Lung after mets from uterus. Leiomyosarcoma. (sp) A month ago she was coughing every 2 minutes, now not so much but she is tired has nausea and the headaches. No appetite and when she ate solid food it would always come back up. Now her food consists of 4- 6 smoothies a day. Got a Vitamix after many recommended it on other websites on the internet. You fellow patient who have gone before her and have reported your experiences are the "only" thing that have kept her pressing forward. She has large tumor in chest and it is hope that this will hollow it out or something. Her first Chemo GEMS/Taxol only worked for 3 months . Then it started regrowing"

• Meano
• Taken for 6 months to 1 year
• February 15, 2020

Votrient (pazopanib) for Soft Tissue Sarcoma "I was on Votrient for 6 months at 600 mg a day. The diarrhea, fatigue and cramping was so bad that I got off the treatment. While on it, my tumors and nodules were shrinking. I immediately felt better when I got off the treatment so I golfed, rode my bike and had a wonderful summer. After a summer being off Votrient, my doctor talked me in to trying again at a lower dose. I started over at 200 mg for a month and felt good so I increased to 400mg a day. Started to feel fatigue and decided to stay at this dose. Its been 4 months now since I started over and all tumors and nodules have shrunk considerably and uptake on PET scan is wayyy lower. It seems to be working. Thinking now about going back to work if I could just get past the need for afternoon naps. I feel blessed. It could be so much worse. Glad I tried Votrient again at a lower dose."

• plane...
• February 6, 2018

Votrient (pazopanib) for Renal Cell Carcinoma "Left nefrectomy 2007, Whipple 2008, left adrenalectomy 2009, 2 craniotomy (2010, 2017). Cancer found in 2007, had spread to Duodenum, lungs eventually adrenals and brain. IL2 in 2008 nailed the pulmonary mets and was NED for a few years before RCC showed up in adrenal and eventually brain (twice). Now RCC has reappeared on remaining adrenal. Using Votrient at a low (400mg) level, and first few months have shown a tremendous reduction (50%). Blessed to have only a few side effects compared to you guys.. . Keep up the energy. . keep up the fight."

• Rockc...
• December 29, 2016

Votrient (pazopanib) for Renal Cell Carcinoma "My right kidney was removed in January 2016. My Oncologist had me undergo a CT scan every 2 months. In August 2016 tumors in my lungs and lymph nodes showed significant growth. A biopsy of several lymph nodes revealed renal cell cancer and I started taking 800 mg/day of Votrient in September. After 3 months, I just completed my first CT scan and virtually all of the tumors from the previous scan had reduced in size, some as much as 50%. I had difficulty adjusting to the Votrient initially. I take Prilosec for acid reflux and my Oncologist told me I could only take a dose in the morning if I take the Votrient at night. I have been able to control the acid reflux by drinking Aloe Vera juice before bed time and raising the bed headboard."

• votri...
• February 22, 2017

Votrient (pazopanib) for Soft Tissue Sarcoma "My wife has a very aggressive cancer that started in the uterus (removed a 2.5 lb tumor last June) which had metastasized to the lung and elsewhere. She was stage 4 at diagnosis. Two chemo drugs did not work. After a bad spell at Christmas (including kidney failure) they were talking about hospice but also wanted to try votrient. The votrient resulted in visible tumor shrinkage within 24 hours. We have continued with the votrient and after six weeks the lung tumors shrank by 20 and 30 per cent. The doctor tells us we may get one more good scan and then it may stop working. But the reprieve has been sweet and things are going in the right direction. She takes 3 pills (600mg) not 4. About the fatigue: she gets some low dose Ritalin."

• Slk
• Taken for 1 to 2 years
• August 8, 2018

Votrient (pazopanib) for Renal Cell Carcinoma "Been on 600 mg of votrient for 1 1/2 years. No new cancer cells and the few I had after right kidney removal and brain tumor removal have decreased. I do experience stomach pain and fatigue but it is not that bad since the cells are smaller and some non existent- stage 4 RCC since October 2016"

• Scott...
• Taken for 1 to 6 months
• January 18, 2018

Votrient (pazopanib) for Renal Cell Carcinoma "I took 800 mg for my RCC for 7 weeks. The medicine made me very ill and caused a few pretty serious medical complication throughout my digestive system but...all signs of my stage 4 RCC are now gone. Votrient was a rough ride but in the end it worked beautifully. Praying I can stay cancer free forevermore."

• Biker
• Taken for 5 to 10 years
• August 23, 2020

Votrient (pazopanib) for Renal Cell Carcinoma "I was diagnosed with stage IV RCC October 2014. Had spread to adrenal gland, lungs, lymph nodes and had attached itself to my bowel and vena cava. Had an attempted nephrectomy December 2014 but failed. Kidney was embolised just after this. I started on 800 mg Pazopanib January 2015 and have been on that dose ever since. My hair has gone white, get fatigued easily, incredible diarrhea at times and other minor side effects but I have no discernible tumours now and am able to work, live life and keep my fingers crossed that it keeps working. I know how incredibly fortunate I have been and I am full of gratitude."

• Johnn...
• Taken for 6 months to 1 year
• February 5, 2020

Votrient (pazopanib) for Renal Cell Carcinoma "I was diagnosed with stage 4 RCC December 2018. Began 800mg Votrient January 2019. In 6 weeks my tumor had decreased in size by 40% and lesions on lungs had receded. At 11 weeks my blood pressure went very high and I ended in emergency room due to the high blood pressure. Dosage was decreased to 400mg and now at 12 months I am stable. My hair is very white and I have diarrhea many days, but I feel good and can work everyday. I feel blessed to have been treated with Votrient. I hope you all can respond as well as I have to this immunotherapy. My prayers are with you all."

• PH CRNA
• May 17, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "I was diagnosed with RCC in my left kidney in May 2012. I thought I was cancer free, but a chest X-ray in February revealed tumors in both lungs. I was started on Votrient 600 mg initially for 4 weeks, and stopped taking drug for 3 weeks due to elevated liver enzymes. For the past 2 weeks I have been taking 400 mg. I have scans in 4 weeks, and am hoping for success. I now have fairly severe back, and flank pain, weakness, and elevated BP. I have labs repeated in a couple of days, and hope my enzymes are near normal. I guess this is the price we pay for trying to stay alive. Best of luck to everyone."

• DIY
• April 21, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "I was diagnosed with Renal cell Aug 2016 . Started in my left kidney met to lungs and vena cava . Still have both kidneys and have been on Votrient 800 mgs whole time I take it at night . Hair , all hair , is white. Side effects, tired, bad mouth taste, some gastric and lose of appetite. First ct tumours were shrinking have another soon . Good luck and God Bless to all cancer fighters ."

• Anonymous
• September 29, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "I have been on Votrient since April. Had to stop after 2 weeks because blood pressure put me in hospital being to high. Started taking it again at 1 a day . I am now up to 4(800mg) a day. Doing better the longer I take it. Have more good days where I feel like doing my house work. Food doesn't taste good. I can eat fruit. Pineapple, grapes, canteloupe things like that. Even some Chinese food some days like sweet and sour chicken. Chicken tastes best . No beef or pork tastes good. Took my second CT Scan this week waiting on results. First one said it hadn't grown any so that's a plus. I too have many side effects. Diarrhea the worst. Fatigue,taste, white hair everywhere, my hands are beginning to get very rough also. I have bruises comes up too"

• SSir
• Taken for 1 to 2 years
• July 13, 2018

Votrient (pazopanib) for Soft Tissue Sarcoma "This June I have competed 1 year with this tablet. I had started 800mg dose per day on 1st June 2017. The side effect I had gone through initially was diarrhea, and mouth sores. I am still on these tablets. The sizes of tumor are under control and suv uptakes are gone down. Fit and fine, no side effects now. Looks like body has got adjusted to these tablets."

• Anonymous
• May 8, 2016

Votrient (pazopanib) for Renal Cell Carcinoma "my husband has renal cancer . he did partial nephroctomy in his right kidney on 9/2010. many tumors appeared later in small sizes in both kidneys. now he is on votrient 800 mg 35 days ago.. he has high blood pressure treated .. rare weakness and bad taste.. little bit problems in stomach.. pain in leg.. his hair started to b white.. we r looking for positive result . hope this treatment can shrink or remove the total tumors"

• G-Gra...
• Taken for 6 months to 1 year
• July 1, 2017

Votrient (pazopanib) for Renal Cell Carcinoma ""Had a partial nephrectomy of the right kidney in 2005. The tumor was papillary renal cell. In Jan. 2016 the cancer reoccurred in several locations in the omentum. Surgery in June 2016 removed a portion of the frontal omentum including papillary renal cell tumors. Multiple nodules still remain in the omentum on both sides of my body. Have been taking 600 mg of votrient since Nov. 2016, now 8 months. Shrinkage by as much as 50% have occurred in some tumors. None have increased in size during the period. Some initial side effects, hypertension, nausea and weakness, have improved during the period; others, diarrhea, taste and poor appetite, remain. At the age of 87 I am trying to stay active. Praying for improvements for all of us."

• Kate...
• Taken for 5 to 10 years
• December 15, 2020

Votrient (pazopanib) for Soft Tissue Sarcoma "I'm taking Votrient for over 5 years, it stopped the spread of mets. Just before I started the trial, every scan like mr,ct,pet was showing new mets, I had clinical chemo like doxorubicin, ifosfamidum, and it stopped only for a while. My oncologist was always suggesting me votrient but it’s the 4 th line treatment and expensive for the government(complicated to explain when health care is for “free” in my country. Anyway for me was the last option. The regional CEO oncologist refused me the treatment. But mine oncologist a research and send me to a capital hospital. So that since 18.9.2015 I’m on Votrient 1st Of all I had no side effects, then after half year, I started having nausea, diarrhoea, fatigue. And of course my skin is as pale and cannot find the lightest foundation tone, and colour my hair and henna brows and lashes...."

• Grammy
• Taken for 2 to 5 years
• June 10, 2019

Votrient (pazopanib) for Renal Cell Carcinoma "Discovered renal cell carcinoma in right kidney and had it removed in 2013. In 2016 it metastasized to liver. Had radioactive isotopes placed in three tumors in liver. Started taking Votrient 800mg. but couldn’t tolerate it so was cut back to alternating 400 mg and 200 mg. every other day. My tumors have shrunk and kept cancer at bay now for 3 years. I have terrible diarrhea, stomach pain, loss of taste and appetite, all white hair, dry heaves. However I take it at night and am on the toilet half the night but I wake up each day and thank the Lord for another day!"

• Kidney...
• Taken for 6 months to 1 year
• November 28, 2016

Votrient (pazopanib) for Renal Cell Carcinoma "My husband was diagnosed with right renal cell cancer May 2014. A brain tumor was found on an MRI that same month, along with small spots on lungs. Gamma Knife procedure done May 2014. Right Nephrectomy June 2014. Brain tumor removed September 2014. He didn't start Votrient 800 mg until December 2015 due to a small spot they found on the left kidney during a routine CT scan. Since taking the medication, his hair has turned from red to white. Other side effects include high blood pressure, nausea, diarrhea and being tired. He was on blood pressure medication prior to taking Votrient. Now he is on three blood pressure meds and now the blood pressures are within a normal range. Spots may or may not be cancer. So far, tolerating med well."

• meo...
• Taken for 1 to 6 months
• April 29, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "Left nephrectomy in July 2015 for large renal cell tumor. First bad CT was in Nov 2016 which showed multiple lesions throughout abdomen and pelvis. Biopsy in Dec2016 confirmed recurrence of rcc. Started 800mg votrient in Jan 2017. Horrible side effects with fatigue and intense abdominal pain. Stopped after 3 weeks and took a week break before starting 600mg. Side effects eased slightly but blood work showed poor liver function after 3 weeks so took a week break and started 400mg. CT in March 2017 showed several lesions 10% smaller. Side effects have calmed down with the worst being daily diarrhea and inconsistent appetite. ALL hair turned white. Good Luck to everyone."

• Anonymous
• Taken for 1 to 6 months
• July 8, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "I'm 66 year old male. Had radical nephrectomy of left kidney in 2011. Scans showed huge tumor. 6years later had nonstop headache for about 4 weeks. Scans showed Tumor on cerebellum. Had surgery to remove that on 10th May 2016. That left me with palsey down my left side as tumor and surgery damaged 7th cranial nerve. Now use walker and wheelchair. Now a tumor has showed up in stomach. Went on Votrient, effects were vomiting, diarrhea, all hair turned white, unable to get out of bed, loss of appetite, no taste. I started using cannabis oil which helped alleviate nausea and loss of appetite. Last scans about two months ago, tumor couldn't be seen. Oncologist didn't say it was gone but it couldn't be seen, where as prior scan showed it clearly"

• l59
• January 28, 2018

Votrient (pazopanib) for Renal Cell Carcinoma "My mum is soon to be 90 and had never been in hospital only to have her four children. Mum got pneumonia and in November, 2017 was in hospital for 6 days. Diagnosed with pneumonia and an enlarged heart. Mid December, 2017 she came back to hospital with laboured breathing. Tests done showed collapsed lung due to fluid and to our shock later diagnosed with RCC, gone into Renal Artery and met to liver. By Wednesday 24th January 2018 she started on Votient, 2 a day. She already has white hair so I don't think that will change but she was taken off blood pressure tablets in hospital (which she had been on for 50 years) as her blood presssure was perfect. On Votient it has gone up again so am taking her tomorrow to see if they want to put her back on them. Mum has 20 great grandchildren and 12 grandchildren and wants desperately to be able to go to my sons wedding in March and her birthday is 1st May. The oncologist is confident that she will make both....Here's hoping"