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Prilosec User Reviews & Ratings (Page 2)

Prilosec has an average rating of 6.8 out of 10 from a total of 50 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Prilosec

  • barb
  • June 5, 2018

For GERD "?Works ok. But I can't get into the package! I'm 74 and have arthritis; it took me 20 minutes to stab and poke and get the darn pills into the daily boxes. If I try to push the pills out the little aluminum bubble, my nails break. I will certainly not use this stuff ever again; it doesn't seem like rocket science to make the pills actually AVAILABLE!!!! B (I hope this is helpful, even though it is grouchy)"

5 / 10
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25 Report
  • ETano
  • Taken for 2 to 5 years
  • April 8, 2018

For GERD "I have taken Prilosec 40mg once a day for 4 years now. It manages my GERD well. Without it I would have severe reflux and have a damaged esophagus and stomach. I have had no side effects that I am aware of."

9 / 10
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25 Report
  • whimp...
  • February 4, 2013

For GERD "Prilosec has always worked for me since I went off Nexium but I recently tried the flavored one and I can no longer take just one pill a day to keep the burning away....so off to the store today to get my regular Prilosec since I have finally finished the flavored box. No more of the flavored one for me."

10 / 10
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39 Report

Frequently asked questions

  • Robbie
  • Taken for less than 1 month
  • November 4, 2020

For GERD "I was prescribed Prilosec 20 mg/day for dysphagia. I took it for one week. The dysphagia was alleviated, but I began to experience bad knee pain. After two sleepless nights, I discontinued it. Knee pain has subsided."

5 / 10
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16 Report
  • lambnj
  • July 11, 2011

For GERD "Prilosec completely eradicates the severe reflux I suffer from due to a rare stomach condition known as gastroparesis. Sadly, it completely eliminates my appetite as well. It also slows my metabolism down to a crawl, which is already inherently slow due to my stomach condition. "

5 / 10
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42 Report

Are you taking this medicine?

  • Sunny...
  • January 5, 2017

For Stomach Ulcer "I was told to take this after what turns out to only have been a nasty stomach virus. Hospital thought it was ulcer. By day four of a 14 day course, I developed severe gum pain and it hurt to chew, I had a horrible taste in my mouth that wouldn't go away, throat gurgles that kept me awake, and shoulder pain. A quick internet search prompted me to quit this drug."

1 / 10
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26 Report
  • ASTXRR
  • Taken for less than 1 month
  • January 31, 2022

For GERD "I was recently prescribed Prilosec after a few years of digestive discomfort and multiple medical appointments to diagnose and treat. Previously I was prescribed Famotidine which provided some relief but Prilosec resolved all symptoms I was having- shortness of breath, abdominal discomfort, inability to lay on one side, and acid reflux. After one week I feel remarkably better and plan to taper treatment after a few months. I've had no side effects and understand that Prilosec isn't recommended for more than 12 months of use, as with most other prescription drugs including SSRI/antidepressants (which most people stay on for many years)."

10 / 10
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9 Report

More FAQ

  • bria
  • June 29, 2011

For GERD "I started taking one pill a day in October, switched to generic, which didn't work so the doctor suggested I take 2 a day. Still nothing, so I switched back to Prilosec and continued to take twice a day. Works pretty well, except for some days when I need to use a backup of tums or Zantac."

7 / 10
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33 Report
  • Old...
  • Taken for less than 1 month
  • September 28, 2019

For GERD "While this medication works well, it’s packaging is the worst I’ve ever encountered. It’s a struggle to push the pills through the tough foil and paper bubbles —- bends my nails and requires at least two minutes to get out a pill. It should be a few seconds. No one tested this packaging with consumers. No one cared. Some genius just designed it on the basis of “sustainability” not taking into consideration the frustration it would cause"

5 / 10
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14 Report
  • Angel
  • Taken for 1 to 2 years
  • January 27, 2023

For GERD "I use to take it & it did work but Had to stop bc I kept on getting bladder infections & When my doctor Took me off of it I stopped getting bladder infections so please be careful with this medicine"

9 / 10
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5 Report
  • John...
  • Taken for 1 to 6 months
  • February 12, 2022

For GERD "After taking Omeprazole for several months I developed an almost complete loss of taste. It had been prescribed by an ENT specialist. When I reported this development to my primary care doctor she told me that she had three patients told her the same thing in the past month."

1 / 10
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7 Report
  • SMM
  • Taken for 2 to 5 years
  • July 28, 2022

For GERD "Female , early 40s, GERD started mid 30s. But Meh, no negative side effects but I try to get by on pepcid until I have a bad flair and then go the PPI route for a bit in case there's some mild gastritis too...overall probably works better than nothing but it doesn't take away chest pressure or that stuck feeling in the throat ( I typically don't get the burn) . I mean even on this medication you cannot eat whatever you want. Drs seem to love this drug as option, as I've asked for anything that actually works and they say all PPIs work the same so...bottom line, don't expect a miracle at all- PPIs work great the first time you take them, then IMO become much less effective. I do imagine it probably helps calm down gastritis/ulcers better than it helps GERD."

3 / 10
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3 Report
  • XmyXo...
  • October 11, 2011

For GERD "I am on 40mg of Prilosec for GERD and I have zero heartburn 24 hours a day 7 days a week. Do not forget to take a dose or else the fire monster comes up your throat."

10 / 10
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74 Report
  • Connie
  • Taken for 10 years or more
  • October 20, 2019

For GERD "Prilosec works fine - as long as I take it daily. But I'm worried about the effects of long term PPI's."

10 / 10
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28 Report
  • Anonymous
  • February 12, 2012

For Barrett's Esophagus "Works as well as pantoprazole for me. Relatively expensive."

10 / 10
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53 Report
  • Anonymous
  • Taken for 1 to 2 years
  • June 22, 2015

For GERD "This stuff works great with no side effects. I had my gallbladder removed and was suffering from GERD. My doctor prescribed me this. Now I can eat whatever I want with no heartburn."

10 / 10
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41 Report
  • boydg...
  • Taken for 2 to 5 years
  • November 4, 2013

For GERD "Its the best PPI I've tried."

10 / 10
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44 Report
  • Anonymous
  • September 28, 2009

For GERD "Prilosec is the only new drug I have used and I find I have insomnia. I am going to stop using this and see if it clears up."

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56 Report
  • Candi
  • Taken for less than 1 month
  • January 31, 2017

For GERD "It's effective however the side effects are horrible"

5 / 10
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32 Report
  • genop
  • October 9, 2010

For GERD "Needed to stop taking due to red, swollen and painful joints side effect. Tried stopping then starting again but side effect occurred again."

8 / 10
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50 Report
  • j lynn
  • September 18, 2008

For GERD "I have Crohns' Disease along with GERD and Prilosec works very well for me. I live by the stuff, it's the only thing that has ever worked."

10 / 10
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55 Report
  • Anonymous
  • April 5, 2012

For GERD "This medicine did not work for me at all. Even with dietary changes I would have occasional flare ups."

2 / 10
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30 Report
  • Nic
  • Taken for 1 to 6 months
  • November 8, 2018

For GERD "This was a game changer - nothing else even remotely helped with my terrible pregnancy heartburn except Prilosec. It helped reduce the symptoms by about 80-90%."

9 / 10
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11 Report
  • pauley
  • February 20, 2009

For GERD "I tried Prilosec first for my heartburn symptoms but I noticed I had to take it a couple of times during the day which quickly added up. I found myself spending quite a bit of money."

4 / 10
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20 Report
  • Anonymous
  • December 8, 2011

For Duodenal Ulcer "Prilosec replaced a treatment that consisted of 800 mg Cimetidine about a week ago and seems to be doing the trick nicely."

8 / 10
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16 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.