Ofatumumab User Reviews & Ratings (Page 3)
Brand names: Kesimpta, Arzerra
Ofatumumab has an average rating of 7.1 out of 10 from a total of 83 reviews on Drugs.com. 57% of reviewers reported a positive experience, while 17% reported a negative experience.
Reviews for Ofatumumab
- Mar...
- Taken for 1 to 2 years
- June 7, 2025
Ofatumumab for Multiple Sclerosis "It stopped the progression of the disease, and I even had healed lesions, a new myelination of my brain cells. I only experienced big side effects in the first dose. Because I live in Portugal, the drug is totally free for me."
- Sta...
- Taken for 1 to 2 years
- May 3, 2023
Ofatumumab for Multiple Sclerosis "I have been on Kesimpta for 2 years. I have a bit of a love/hate relationship with it. Pros are it was only one jab a month after the initial start-up jabs. Minimally impacts my life, and it’s quick and simple. Cons are that it stings when I do the injection, and I immediately get a 24-hour headache the minute it hits my system. I do get a little more poorly if I get an infection."
Frequently asked questions
- IHa...
- Taken for 1 to 6 months
- April 27, 2022
Ofatumumab for Multiple Sclerosis "About to take second dose. I don’t like how I feel on this drug. Migraines are worse. I’m more fatigued. I began the drug because of its ease of taking once a month via self-injection. I wanted to go back to work full time. However, I’m too tired to do the job. Can’t think clearly because I’m too fatigued. Going back to Tysabri."
- Dar...
- Taken for 6 months to 1 year
- March 15, 2024
Ofatumumab for Multiple Sclerosis "I was diagnosed with RRMS. I've been on Kesimpta for 10 months, it is very convenient and easy to administer. So far, I've had no issues with Kesimpta. My recent full MRI showed no further progression."
- Gro...
- May 1, 2023
Ofatumumab for Multiple Sclerosis "I just finished my initial doses. All were different, the first dose I got a sore throat, itchy without a rash, went to bed, and woke up with the most excruciating muscle and joint pain I've ever experienced. Dose number two hurt more than the first, my throat was sore and I was again itchy all over without a rash, but no body aches. Dose three was only the itchiness, but I just didn't feel good for about a week. I had all my injections on a Sunday. For the first two, on Thursday, I had some minor vertigo and a short-lived temp increase to about 101 F. I rotated my injections on my thighs, however, with each injection, I felt like I received an injection in my left upper arm. Very weird."
- HHD...
- Taken for 2 to 5 years
- July 24, 2024
Ofatumumab for Multiple Sclerosis "I feel that it's been working very well for me. I take it once monthly at home. In the initial build-up phase, I had some very minor breathing tightness and stomach problems, but that ended after I reached maintenance level. Recently, I've had some infections that I haven't felt I needed to take antibiotics for, just working on natural solutions, and they're improving. Otherwise, I'm very happy with the medication; it's easy to take, just once a month at home with no negative aftereffects, and I just go on with my day."
- Chu...
- Taken for less than 1 month
- September 17, 2023
Ofatumumab for Multiple Sclerosis "Was on Ocrevus for about 3 years, seemed to not be working as well as before, so the doctor switched me to Kesimpta. Just finished my first 3 shots with no real side effects, other than feeling a little tired after the first two. Looking forward to seeing how it works in the future."
- Kat...
- Taken for 1 to 6 months
- June 15, 2024
Ofatumumab for Multiple Sclerosis "I have had eight doses, including the loading doses. My side effects have mainly been exhaustion, though I have slowly lost my appetite, and recently felt highly nauseous. My MS symptoms are steadily declining, pain, weakness, stiffness, etc., but without Kesimpta I may be a whole lot worse. The medication needs at least a year to really work too. Overall, without any other real choices, I am happy to keep having the Kesimpta injections."
- eli...
- Taken for 6 months to 1 year
- August 9, 2024
Ofatumumab for Multiple Sclerosis "First dose - horrible flu-like symptoms with fever. Tylenol helped. After the first dose, it was better with no noticeable side effects. I have taken it for close to a year. Over time, I realized it is likely triggering heart arrhythmias. I seem to have less pain when I take it. Other than that, I don't know for sure if it is helping or not."
- Ano...
- Taken for 6 months to 1 year
- April 6, 2025
Ofatumumab for Multiple Sclerosis "I have been on Kesimpta for 6 months, and so far, so good. Have had MS since 2007. Before Kesimpta, I was on Ocrevus for about 9 years until my insurance wouldn’t pay for it. My doctor said Kesimpta was comparable, which it seems to be. Been using a cane the last 4 years but staying the same. Brain fog is less, and a little more fatigue, but life has gotten harder, so may have nothing to do with the drug. Will see and will post an update in a few months."
- aba...
- Taken for 1 to 6 months
- February 22, 2025
Ofatumumab for Multiple Sclerosis "I was very hesitant to try this with all the negative reviews. I know everyone is different, so some will get the side effects and some will not. I treated this the same way I treated Rebif when I was on it years ago. I took an IBP 800, took the shot, and went on with my day. I had no side effects since I took the IBP. If you've ever been on the shots, it's the same, just a smaller needle and I didn't even feel it. I was on Adagio before this for 7 years, and it did well until the end. It made me tired, so I took it at night, and it made my hair thin and nails brittle, but they all seem to do that. I would highly recommend either of these meds. Side effects are not as bad as people describe them as! With Kesimpta, just take Advil or Tylenol beforehand and you'll be fine."
- Jes...
- Taken for 2 to 5 years
- July 25, 2025
For Multiple Sclerosis "The initial loading doses had bad side effects for me like fatigue, weakness, headache, nausea, and chills. But the medication had gotten more tolerable over many months. I feel nauseous, hot and cold, and fatigued for about 5 days after my injection, then I feel okay again. It’s been great for my MS - I haven’t had any new lesions on Bonspri/Kempista."
- Nay...
- Taken for 1 to 6 months
- February 3, 2025
Ofatumumab for Multiple Sclerosis "I have RRMS, and I recently started KESIMPTA. So far, I love it. I actually feel like it gives me a boost of energy in the days following. I like to take it at night to avoid all of the initial symptoms. I love the ease of doing it myself and all the help I get from the KESIMPTA team."
- den...
- Taken for 1 to 6 months
- May 19, 2023
Ofatumumab for Multiple Sclerosis "The best medicine ever. I have my energy back, my eye issues are gone, and I have reduced pain that does not linger all day. Used Tecfidera and Avonex. I have days that I forget I have MS."
- Che...
- Taken for 6 months to 1 year
- March 13, 2022
Ofatumumab for Multiple Sclerosis "Haven’t had any side effects or relapses with Kesimpta. I do have headaches and aches/pains, but they were there before Kesimpta. Easy to use, feeling positive about it."
- Lif...
- Taken for 1 to 2 years
- July 10, 2025
Ofatumumab for Multiple Sclerosis "I have been on Kesimpta for a year. I have improved from being bed bound to getting my life back."
- Ann...
- Taken for 6 months to 1 year
- February 20, 2023
Ofatumumab for Multiple Sclerosis "This drug is amazing. No side effects, no new lesions, very minimal sickness. In fact, I got COVID while on it and recovered quickly."
- Hoo...
- Taken for 1 to 6 months
- February 4, 2021
Ofatumumab for Multiple Sclerosis "I have MS, and I am on Kesimpta. So far, no issues, and it is so easy to take. It is only once a month, too!"
- Fre...
- Taken for 1 to 6 months
- December 5, 2023
Ofatumumab for Multiple Sclerosis "4th dose 3 days ago and feeling weak, numb legs, sick, dizzy. Really hope it goes away. I'm a bit scared."
- Hbe...
- Taken for 1 to 6 months
- November 26, 2022
Ofatumumab for Multiple Sclerosis "Symptoms seemed to get worse. Not drastic, but symptoms I already had seemed to be more pronounced."
- mar...
- Taken for 6 months to 1 year
- June 11, 2023
Ofatumumab for Multiple Sclerosis "I love this medication. I have had no side effects and have pain maybe once a month. I feel like a completely healthy person."
- Sat...
- Taken for 1 to 2 years
- December 2, 2021
Ofatumumab for Multiple Sclerosis "I love the once-a-month injection, instead of three times a week. The first shot I got sick, which was explained to me that I would after that clear sailing. No relapse!!!!"
- And...
- Taken for 1 to 6 months
- April 5, 2022
Ofatumumab for Multiple Sclerosis "Taking Kesimpta, first dose had hot and cold sweats on first night, after that, felt fine. Taking other doses now, on my fifth month and feel fine. No side effects now."
- Anonymous
- Taken for 1 to 6 months
- March 21, 2023
Ofatumumab for Multiple Sclerosis "My condition improved soon after starting. In particular, my balance is better, and leg spasms were controlled. No side effects."
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- During pregnancy
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Ofatumumab for Multiple Sclerosis "Starting Kesimpta 3 yrs ago brought me back from the brink of being nearly wheelchair-bound. I have had a huge increase in catching every sickness, but I do have an elementary-aged child, lol. One thing I didn't notice until missing a full month's dose (bc recurring sickness) is increased leg pain. When I finally injected my dose, I was so overwhelmed with pain, like how did I live like this?! But like before, I became accustomed to this level of pain in about a week or two. It's not all sunshine and rainbows, and it doesn't work for everyone, but the benefits outweigh the costs for me. Also, I feel like a hot, soggy dumpster for a day or two after my dose. But it beats the side effects from other meds I've tried."