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Nortriptyline User Reviews & Ratings (Page 4)

Brand names: Pamelor

Nortriptyline has an average rating of 7.3 out of 10 from a total of 543 reviews on Drugs.com. 68% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Nortriptyline

  • Grac
  • March 16, 2013

For Migraine Prevention "Been having worsening migraines for 8 or more years. Tried so many different things, I am basically disabled at this point sick almost daily from either migraine or rebound day. After Topamax, steroids, beta blockers, you name it I've tried it. Finally I've been put on nortriptyline, after 2 weeks I haven't had a single migraine. I hate to be skeptical but it's almost too good to believe for me since I've been sick so long, so I will be reporting back soon. But I even feel differently just how my brain feels. Right now I'm quite thrilled and the results seem to be what's reported by everyone else here (taking 25mg at night)."

10 / 10
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  • freedom
  • July 12, 2017

For Irritable Bowel Syndrome "One of the first reviews I've written regarding a treatment. My IBS-D got to a point where I was visiting the bathroom about 5-6 times a day. When I wasn't in the bathroom the uneasiness associated with IBS stopped me from focusing on anything I tried to do. All I wanted to do was stay in bed and distract myself with movies and TV shows. I spent lots of time researching online and trying various treatments including elimination diets, supplements, various exercises etc.. My GP recommended I try Nortriptyline at nights starting at 10mg dosage and said that it'd take around a month to kick in. After about 3 weeks I switched to taking it in the morning and it's been working wonders every since. Pretty much IBS free and have my life back."

10 / 10
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  • Anonymous
  • January 13, 2014

For Migraine Prevention "I'm a 47yo male who has suffered from migraines for about 30years. They have increased in frequency and duration over the last 2years to the point where I sought preventive therapy. I tried propanolol, various muscle relaxers and most recently nortriptyline. I started with 10mg taken at bedtime with little relief. Eventually, increased dose to 75mg and am happy to report migraines have decreased from 2-3 week to 2/mo. Still have to stay away from triggers such as alcohol and chocolate. Only side effect seems to be short term memory loss."

8 / 10
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104 Report

Frequently asked questions

  • Erica...
  • Taken for 6 months to 1 year
  • May 14, 2016

For Pain "Took this for nerve pain and it helped! Except I would rather ache & have nerve pain than deal with the side effects I experienced. I kept getting nightmares that were so horrific, I eventually started sleeping with the lights on & thus not sleeping as good. Within 6 months I gained 20 lbs without changing my eating habits nor physical activity. Looking back, there was a short period of time when my vision was affected as I had trouble focusing. At the time, I just thought my contacts prescription was getting too strong for me. I decided to revisit the list of side effects and sure enough there they all were. I quit taking Nortriptyline that day and eventually the nightmares, blurred vision, & weight gain went away."

3 / 10
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85 Report
  • Janine
  • Taken for 5 to 10 years
  • September 26, 2019

For Panic Disorder "This medicine nortriptyline saved my life. Back in 2013 I woke up with panic attacks and anxiety through the roof. I had to end up going on disability twice and none of the regular depressants/anxiety medications would help. Found an amazing psychiatrist who put me on this life-changing medication. I am on 125 mg a day and it completely got rid of my anxiety and depression. No more panic attacks. I do take Ativan just in case I feel the anxiety coming on strong however the nortriptyline really helps control it. I recommend this medication to anybody with anxiety/panic/depression. You do need to give it time. The first time I was on it within two months I was cured I did get off it for a while to see if I needed it and I sure did. When I got back on it the second time it took six months to work. Be patient."

10 / 10
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56 Report

Are you taking this medicine?

  • CJCJC...
  • November 15, 2015

For Migraine Prevention "I never write reviews but for this drug I feel like I have to! I have tried so many drugs, herbal supplements, chiropractor, massage, acupuncture etc. have been hospitalized before for my migraines, and at some periods had them everyday. I thought if this is the reality of my life being in pain everyday, what is the point? This is the only drug which works and has almost no side effects except for at first a dry, nasty tasting mouth which has gone away for the most part. It took a couple days to kick in and I'm on a very low dose of 10 mg which I take at night. It's been almost a week pain free! I feel like a new person and it finally feels like the miracle I've been looking for, so don't give up!"

10 / 10
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  • stace...
  • June 5, 2010

For Pain "I am still in the early stages of using this medication. My fourth week. It has really helped with the back pain. Although I still feel pain, it is not continuous in all areas of my back. It is now just if I tweak the source. I did not heed the warning to avoid alcohol the first week and was very ill as a consequence. I was vomiting for 2 days afterwards and very dehydrated. My own fault. I am going to speak to my doctor to see if we should add to the dosage to try and get rid of the pain completely. I am currently on 10mg per night. Although I don't drink much, I do feel that I don't have the freedom to choose if I would like to drink. So, this is the down side to this medication. However, I would love to get rid of back pain for good!"

7 / 10
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125 Report
  • pam
  • September 26, 2013

For Migraine Prevention "I was prescribed this medication because my migraines were increasing and my sleep was getting very erratic. Since taking this medication for the past month, I have slept throught the night and it is easy for me to fall back asleep if I wake up to use the bathroom. I am so glad my doctor suggested this. After 13+ years of bad sleep and increase of migraines, I think I found something that works without any side effects (thus far). I take about 1 hour before bed and it has worked like a charm."

9 / 10
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  • Neenee
  • Taken for 2 to 5 years
  • March 12, 2023

Pamelor (nortriptyline) for Depression "I have to give this drug the best review possible. No exaggerating,, this medicine saved my life and helped me to learn about how much I don't know about depression and the self medication I resorted to, was no longer needed. This self medication that was destroying my life was no longer needed or desired. It helped me to understand that's what I was doing because of mental health struggles and that I was deserving of a better life. All I can say is Thank you!!"

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  • birdo...
  • October 17, 2010

Pamelor (nortriptyline) for Migraine Prevention "I've suffered from migraines for 14 years and have taken numerous medications for prevention including Topamax (Topamax caused MANY bad, undetermined health issues). My Internal Medicine physician took me off Topamax and put me on 25 mg of Nortriptyline for migraine prevention. Almost immediately, I had relief from migraines, had clarity of mind even better than ever before, had a great attitude. I felt "normal" for the first time in my life. This medication caused noticeable urinary retention, constipation and increased appetite which caused weight gain. Due to weight gain, I was changed to Pristiq. Migraines have returned. I intend to ask to be put back on Nortriptyline and will have to alter diet and exercise."

10 / 10
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122 Report
  • Lia...
  • Taken for 2 to 5 years
  • March 10, 2014

For Migraine Prevention "I'm a disabled vet due to migraines and have been on many medicines to both prevent and treat. I have botox injections every 90 days and a constant supply of Imitrex injections to which I take approx 8 times a months. I notice a HUGE difference when taking the nortriptyline (75mg a night). I love that it helps me sleep. I just can't forget to take it, if I do: hello migraine."

10 / 10
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97 Report
  • Mousse
  • Taken for 1 to 6 months
  • December 21, 2017

For Irritable Bowel Syndrome "I HAD UNRELENTING DIARRHEA AND COULD NOT LEAVE THE HOUSE WITHOUT TAKING IMMODIUM. My doctor prescribed nortriptyline. I filled the prescription but did not take it because well I almost thought it was foolish. I was not depressed... But then I thought what the heck. I started the 10 mg every night. In 3 days the only side affect was no more running to the bathroom. OMG for me it is a miracle. I do have vivid dreams but that is ok and Also sleep well and feel great when I wake up."

9 / 10
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68 Report
  • Baxter
  • Taken for 1 to 6 months
  • August 12, 2019

For Pain "I have been struggling with progressively worsening never pain, for 10 years. I cannot lift up on my toes on either leg, due to nerve damaged (slipped disc on one leg and some kind of impact arthritis on the other) The nortriptyline has virtually eliminated the nerve pain! I've been taking 25 mg for one month, The so called "side effects" are virtually all positive. Constipation? Great! .. now I can have just one bowel movement per day instead of 5 or 6. Sleepiness? Great, I sleep much better now! I used to take a half dozen each ibuprofen and acetaminophen and 2 naproxen almost every day ... now one ibuprofen some mornings and that's all I need Cannot say enough good things about this product!"

8 / 10
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  • JZ620
  • March 7, 2013

For Irritable Bowel Syndrome "This medication has been a life saver. I am a 23 year old female and was diagnosed with Irritable Bowel Syndrome 10 years ago. It wasn't until 2 years ago that my primary care doctor suggested this medication after finding success with another patient. Only 10 mg a day at bedtime and I am IBS symptom free. I used to have 5 bowel motions a day and now I am very regular. My life is so different now that I am on this medication. When I started the medication I had extreme dry mouth that went away after a couple of months and now I sometimes become constipated (which is something I've never had in my life)."

10 / 10
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102 Report
  • not...
  • Taken for less than 1 month
  • February 4, 2013

For Pain "I take 25mg of nortriptyline at bedtime. I have taken it for 3 weeks. I toss and turn at night and sleep about 3 hours for 2 nights, then on the 3rd night, I am able to sleep 9 or so hours because of lack of sleep previously. It has helped my neck pain considerably, but about 10 days ago, I began getting pain in both my knees and hips, which makes it even more difficult to sleep now. At first, I believed it was because of the treadmill, but I stopped after 2 days using it to heal my knees and hips, but they are still hurting. Also, I am experiencing memory loss. I am 68 years old."

8 / 10
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  • Ms Ja...
  • Taken for 5 to 10 years
  • May 20, 2014

For Neuralgia "I have suffered with A-typical facial neuralgia for over 12 years and nothing but nothing has helped me like Nortriptyline. I was prescribed this by a professor of Pain Management at Walton Hospital and I can honestly say he saved my life. It is a wonder pill that seems to work alone. Previously I was on a cocktail of Tegretol, amitriptyline and gabapentin which completely left me like a zombie. After being 'pain free' for 7 years, I began to wean myself off them but only recently the pain has begun to return so I'm going go back to the doctor for my script. Sometimes it's better to carry on taking the tablets even if you think the pain has gone as they cannot cure you, they merely mask the pain, which is good enough for me."

10 / 10
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  • Rosey
  • Taken for 5 to 10 years
  • September 20, 2019

For Pain "I was prescribed Nortriptyline 50 mg at night for back pain and sciatica in 2012. It helped me sleep with no pain. I did have weight gain, dry mouth, constipation, decreased urination, and heartburn. In 2014 I had right hip replacement. In 2019 most of my chronic pain was gone. My doctor lowered my dosage to 25mg at night per my request. After two months I have finally stopped Nortriptyline. I have more energy, have lost 13 lbs and my memory and concentration halve improved. I sleep all night and feel energetic when I wake up. After seven years I hope to never have to take this drug again."

9 / 10
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  • Rob...
  • August 13, 2015

For Panic Disorder "Had a few panic attacks, which later lead to constant panic attacks. This caused Agoraphobia. Suffered for 3 years and nortriptyline cured me from them 100%. Stopped the Doom and the attacks. I was on it 3 years and all was perfect. Later, I tired many SSRI's and all on them seemed to induce or create panic attacks. When I stopped the SSR's they went away. I have been free from Panic attacks since. It has now been 10 years clear. Thank you nortriptyline.."

10 / 10
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  • Liv
  • Taken for less than 1 month
  • December 6, 2018

For Migraine Prevention "Be careful with this medication if you have struggled with depression or have a family history of mental illness, depression, bipolar, etc.. I went on this for migraine prevention, not for depression and on my second day of taking it, started having really dark thoughts and hit a real low point. I have never been suicidal before and am actually usually the happiest I have ever been but this medication completely distorted my perception of things. Had to go off it a week later as the feelings only got worse."

1 / 10
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58 Report
  • Big...
  • December 23, 2016

For Pain "To those of you who are having nightmares, they will go away. I had them so bad but it worked so well for the low back neuropathy I was finally able to walk again. My back kills me. I take 30 MG throughout the day now. Taking it with tramadol decreases the effectiveness of the drug. Nortryptilline is a tricyclic antidepressant. It blocks the receptors in the cerebellum so pain signals cannot be received. This is not FDA approved because being an antidepressant when one is it depressed can be very risky and cause serious side effects. For those of you who are waking up on this medication, you could be low on serotonin and those that are falling asleep you could have too much. It will also make you very constipated. Be careful."

8 / 10
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  • mjaym
  • Taken for 2 to 5 years
  • July 14, 2015

For Pain "I have Stage 5 CRPS and have been taking 75MG of Nortriptyline (Generic for Pamelor) at bedtime for a few years now. I feel that I have been taking it long enough to say for sure that it helps with my treatment. I recommend this drug, but everyone is different and we all respond to medication differently, I hope Nortriptyline give's you the same hope in your treatment that it has given me."

10 / 10
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83 Report
  • 2Reli...
  • Taken for 5 to 10 years
  • January 13, 2016

For Migraine Prevention "I've had migraines since I was 9. My parents weren't big on doctors so I "bucked up" through the raging pain. I didn't know until my 20's that having headaches every day wasn't normal. When I got married and my husband found me curled in a ball of pain, he didn't take "I'm okay" for an answer and took me to his family GP. The first day I took Nortripylene my migraines vanished. I didn't even know life could be so pain free! It's been 8 years now and I'll happily take it forever to be free from the wracking pain. If I stop, they come back and remind me to get my refill. It has worked wonders for me."

10 / 10
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79 Report
  • ThomasF
  • February 19, 2017

For Depression "I suffered depression and anxiety at a young age due to a stuttering problem but I never knew at that time what caused it. I went to a Dr. at the age of 22 and he put me on Pamelor. I was afraid to take it but I did. The first few days it made me feel weird. I felt like a zombie at first for maybe 3 days but then it went away. In 6 weeks my depression was gone and I felt like a normal person. I was normal. I think my does at one point was 100 which is moderate. People need to know that this type of med takes 6-8 weeks to work and when it does its like a fog has lifted, for me at least. You have to be careful with weight gain because it does increase your appetite. It helped me sleep at night. 6-8 weeks to work."

10 / 10
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  • Night...
  • Taken for less than 1 month
  • July 21, 2016

For Pain "I took the first dose at night because my doc said it may cause sleepiness. I woke up in the middle of the night with a terrible headache and insomnia. Decided to try a second night. This time, no headache but still insomnia. Last night I took my 10th dose and I am awake 2 hours after falling asleep then having a horrible, horrible nightmare about sexual situations, being part of murders, and my son being kidnapped by a killer clown. I know that sounds dumb, but it was extremely realistic and now I can't go back to sleep. I will call my doc in a few hours to discuss tapering off and quitting this med all together. My pain has not been relieved at all (even if it had, I could continue with the insomnia and graphic nightmares)."

1 / 10
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  • Anonymous
  • March 28, 2012

For Depression "I suffer from depression, back pain and anxiety that has been gradually getting worse. I started taking nortriptyline and noticed a number of changes within 24 hours. I finally slept through the night. My back pain dramatically improved and my anxiety lessened. Sounds amazing right? Well yes, but I was also crying all the time and felt even more depressed. I also began having bad thoughts about hurting myself. I have had bad thoughts in the past, but always had control of them. These felt very different, I had no control of them. For some people this medicine is a miracle, but if you start to have thoughts that don%u2019t feel right when you start taking this medication, go to your doctor immediately."

5 / 10
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101 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.