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Linzess User Reviews & Ratings (Page 2)

Linzess has an average rating of 6.6 out of 10 from a total of 866 reviews on Drugs.com. 55% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Linzess

  • Shelly
  • Taken for 1 to 2 years
  • September 1, 2019

For Irritable Bowel Syndrome with Constipation "I have IBS-C and it has made me so sick for years. My dr prescribed me linzess 72mcg. I take 1 tablet on an empty stomach when I wake up. I eat 30 minutes later and within the hour I'm using the restroom. No stomach cramps at all. It gets rid of my stomach pain and I no longer have IBS attacks that make me sick. This medicine has been a life saver. I take my medicine everyday and I skip it on days I'm not near a restroom."

10 / 10
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  • Ronnie...
  • August 24, 2014

For Irritable Bowel Syndrome with Constipation "I took Linzess for about 3 months and IMMEDIATELY began to gain weight. I noticed the weight gain and thought that it had to be my diet. I began cutting back, watching what I ate and nothing was worked. After taking myself off of the medication, I IMMEDIATELY noticed the weight loss. I felt bloated around my entire midsection going all the way around to my back. Biggest I had ever been. Someone commented that they felt 3 months pregnant and that would about sum it up. I think the FDA should disclose that side effect after looking into the medicine more closely."

8 / 10
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  • FANCY...
  • April 24, 2014

For Chronic Idiopathic Constipation "Linzess is awesome. I love it! I suffer from irritable bowel syndrome and chronic constipation, I have had for years and nothing worked. I have been miserable. I used to take zelnorm and it worked good and they took it off the market. My stomach felt like clogged pipes. I have tried everything. My doctor prescribed linzess to me yesterday. I took 1 last night at 9:30 and by 11:30 my stomach was churning and I got up and went to the bathroom and I totally cleaned out with no pain. I never want to be without this, it works. I have a waist line now. I give it a big 10. Thank you."

10 / 10
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176 Report

Frequently asked questions

  • Peg
  • Taken for 1 to 6 months
  • August 26, 2020

For Chronic Idiopathic Constipation "I was put on linzess and every thing was going good then it gave me diarrhea and that wasn't a problem but I skipped taking one , and the diarrhea cleared up but then I couldn't go again after I started back , so the increased it to 290 and the same thing happened and now I can't get it to work at all"

7 / 10
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  • Caitc...
  • July 15, 2014

For Chronic Idiopathic Constipation "I have been constipated for YEARS. Since I was about 16, and I'm now 24. I tried everything from changing what I ate to fiber gimmies and drink mixes, two laxatives, and vegetable laxatives, milk of magnesia, I even drank magnesium citrate. It has been a constant struggle with bloating and cramping. I could gain up to 5 pounds and I was constipated for more than a week, and that even made fitting in my clothes difficult! Send using Lindzess I am never constipated!! I take it every other day, and that is enough for me. My movements aren't hard, but they aren't diarrhea either...play with it and take it as you need it, but it surely is a miracle pill."

10 / 10
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Are you taking this medicine?

  • May...
  • April 8, 2021

For Chronic Idiopathic Constipation "I was prescribed Linzess for IBS with constipation. 1st dose worked so well (145 MCG daily). The pharmacist said to skip a day if need be. Frankly, I hadn't had a full and solid BM (e.g. not raisin - grape/walnut-sized fragments) in a long time. I continued to have several solid BMs the first day/night to the point that I thought it best to skip the next day. The day after dose I went back to "normal" (small, grape-sized BMs). Linzess seems to have "pooped out". I take as directed and drink 3 liters of water daily. I supplemented with 100 MG o-t-c stool softener (didn't help much). I tried an AloeLax 225/ Aloe Ferox - Mill Leaf Resin (helped slightly). UPDATE: I've experienced major inconsistencies with Linzess. I really think that there are certain batches that have been either improperly stored or shipped. My newest Rx bottle seems to work, whereas the last 90 day supply really didn't."

6 / 10
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  • Honey...
  • Taken for 1 to 2 years
  • October 20, 2019

For Irritable Bowel Syndrome with Constipation "Linzess had huge impact on my quality of life. You have to be careful to follow the dosing restrictions. Food within a certain period of dosing especially fatty food will elicit an expedited response from the medicine. This means that the symptoms you may feel which normally might be strung out over a period come fast and hard. I began eating oatmeal for breakfast every day. One high fiber package and one normal. I also keep miralax on hand to fine tune my GI system. Altogether, this medicine used correctly can make a vast difference. I sometimes worry that I have to use this medicine to feel normal but until they come up with something better for IBS-C it's about as good as it gets."

9 / 10
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  • Jen
  • Taken for 2 to 5 years
  • March 19, 2019

For Irritable Bowel Syndrome with Constipation "I don't get any cramping or bloating but Linzess for my irritable bowel keeps me in the bathroom. When I take it my bowel movements are extremely watery, I get so weak and tired. The doctor told me to only take this as needed. We I take if I can't leave the house so I can't take it every day. Has anyone experienced this thank you"

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  • Joy
  • August 13, 2019

For Irritable Bowel Syndrome with Constipation "I've dealt with chronic constipation/ IBS for many years but in my mid-20s, it has been particularly terrible. Bloating and nausea, occasional vomiting after eating. After some trouble getting Linzess approved by my insurance, I am SO grateful for this little pill! -Day 1: nothing -Day 2: serious bout of diarrhea (be warned, you might not make it to toilet in time) -Remaining 2 weeks: again constipated/ frustrated. Was starting to lose hope. -Post-2 week mark: I feel GREAT. I have a good (mostly less urgent) loose stool every couple days. A lot of gurgling/cramping, but anything is better than what I was feeling prior. I still drink a lot of water and exercise to get things moving as naturally as possible. Overall: a true constipation/ IBS-C sufferer like myself, you will welcome the diarrhea with open arms. It has not interfered with my quality of life, I just find a bathroom ASAP if I feel a bowel movement coming. Try to stick it out for at least 6 weeks. :)"

8 / 10
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  • tbeckys
  • Taken for less than 1 month
  • March 9, 2020

For Chronic Idiopathic Constipation "I started Linzess 3 weeks ago. At first it was wonderful and then 1 week later it quit! My GI Dr., said to take it with 3 capfuls of Miralax. I didn’t do 3 but did 2 capfuls! I had diarrhea for several hours! Then went back to 290 of Linzess and nothing! I don’t know what to do as I’m constipated again! I also found out during a colonoscopy several years ago that I have several more feet of bowel than the other people have so that it takes much longer for me to go to bathroom! I really don’t know which way to turn!!"

1 / 10
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  • Hornb...
  • Taken for 1 to 6 months
  • March 31, 2017

For Chronic Idiopathic Constipation "I have been on this for about a week. After 20 years of complete idiopathic chronic constipation I had to take Mag Cit-rate or MOM every three days and wear a depends. It was necessary to stay alive and as I said 20 years (3 trips to Mayo Clinic and no help). I've not had any side effects that I am aware of yet. First morning I took it and had a bowel movement the next morning and it was a substantial and well formed movement. Later that night before bed, I had an urge and had another significant bowel movement. Second day same situation and had good bowel movement when I got up (within 2 hours). If this stays effective and no side effects emerge, my life has changed wonderfully forever. I could not travel before and had to wear a depends after magnesium as I never knew when I would get hit for about 16 hours. I have had no diarrhea with Linzess or bloating or pain. I hope prices go down or a generic occurs as I paid about $350.00 for 30 290mg capsules. Also, I pray that nothing occurs where this shows over time to have any negative side effects. I took Amitiza over 10 years ago and had agony and very poor results. I lost faith in all new drugs as they all panned out to have some serious problems so I waited on Linzess for over 5 years before trying it. No horror stories emerged and now, unless it stops working, I'm truly amazed after 20 + years of constant constipation. I didn't have over two or three Bm'S in 20 years without a magnesium product and they were getting more frequent for use with age. I'm happy to write this because I had given up and had considered having a colostomy or colectomy if I was a candidate. 10 stars for Linzess!"

10 / 10
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  • Lisai...
  • Taken for 1 to 6 months
  • August 8, 2014

For Chronic Idiopathic Constipation "After seeing so many bad reviews of this medicine, it almost stopped me from picking it up from the pharmacy (considering the cost) but I am so happy I did. When I take it it cleans me out with no pain, gas or bloating that I would get from other laxatives. If you have a job or somewhere to be during the day I would not take it in the morning. I am at home with my kids so I follow the morning schedule and within 2-3 hours it takes effect with frequent trips to the bathroom that last for about an hour. On days that I have plans I simply time the medication to kick in when I know I'll be home. I will take a planned one hour bathroom break over feeling constipated and disgusting any day! Take every second day considering how well it cleans you."

9 / 10
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  • Mac
  • Taken for 1 to 2 years
  • May 2, 2014

For Chronic Idiopathic Constipation "Alright so I'll give you the full on details. It works great for me but you definitely don't want to be out of reach of a toilet within an hour after eating because you Have To Go. I suffer from severe constipation, I used to only go to the bathroom once every week and my pain from being so bloated just got ridiculous. Linzess really helps, even if I forget to take it for a few days and get backed up, it works to flush me out. Haha. I know. But still don't know what I would do without it because laxatives are Not good."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 9, 2019

For Irritable Bowel Syndrome with Constipation "I have IBS and my doctor recommended linzess, this was a lifesaver for me I have regular bowel movements now when I take this I make sure I'm not going out of the house for the day cuz it works immediately at least for me it did within 15 minutes to up to an hour your stomach will start bubbling and growling and it helped so much with the bloating I look like I was 6 months pregnant now the bloating is gone my stomach feels better and I get plenty of relief make sure you don't leave your home though when taking this medicine cuz you definitely going to be on the toilet it works for me I'm glad my doctor recommended it."

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  • trago
  • Taken for 1 to 6 months
  • May 22, 2014

For Chronic Idiopathic Constipation "I have suffered with chronic constipation for at least 5 years, I always assumed it was caused by pain medication and opiates. I started methadone treatment about 10 months ago and the constipation got worse. I tried laxatives, stool softeners, drinking tons of water, eating everything I could that gave me fiber in my diet, nothing was helping. It got so bad that going to the bathroom was something I feared. I found myself doing an enema every 2 days. Then they stopped working. I talked to my doctor and he gave me Linzess and about 3 days after the first pill I went to the bathroom. No pain, no constipation it was amazing. I've been taking Linzess for a month now and everything seems normal again. Linzess is my miracle pill."

10 / 10
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  • MissJ...
  • July 11, 2014

For Chronic Idiopathic Constipation "I was diagnosed with Irritable Bowel Syndrome-Constipation 15 years ago and severely suffered with constipation since then. On average I would do a bowel motion once every 2 1/2 to 3 weeks....no exaggeration. I requested a colonoscopy after a friend of mine suddenly died of colon cancer at the age of 31. Year ago my PCP introduced me to Linzess. It took a month for my body to adjust. I do have occasional diarrhea with it but I will take it over constipation any day! It's been a year and I am down to taking it once a week and rather then have a bowel motion once or twice a month. I go once or twice a day lawlessly with no issues whatsoever. It has acted almost like a cure for my condition. Thank GOD for Linzess!"

10 / 10
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  • AnnaM...
  • Taken for 1 to 6 months
  • December 12, 2019

For Chronic Idiopathic Constipation "I dealt with constipation for several years. I would have a BM 1-2 times a week and stayed bloated and miserable. My doctor prescribed 72mcg and it works great. Take 1 and like clockwork have a BM within 2-3 hrs. No more discomfort or gas. I'm very satisfied with Linzess."

10 / 10
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  • Linzizi
  • July 30, 2014

For Chronic Idiopathic Constipation "My doctor gave me Linzess samples and so far it is helping alot. I dont have as much discomfort in my stomach, and less burping and farting. However I did have a VERY embarrassing situation happen when I was walking my dogs one morning, I had no feeling I had to go at all, and just coughed, and out came a liquid mess. SO...overall I like the medicine but the diarrhea can be severe and unexpected. I have never had this happen before!"

9 / 10
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133 Report
  • Stan
  • Taken for 6 months to 1 year
  • June 2, 2020

For Chronic Idiopathic Constipation "Even with side effects, doctors wanted my husband on Linzess because of an ileus and having suffered complete impaction. We've tried for six months to get assistance from Allergan Patient Assistance Program. Mistakes on the first application left the application sitting until I began investigating in March. In May I called to learn of incomplete and erroneous information (my fault since I was using info from 2018 part D plan) and doctor's office providing incomplete and mistaken information. June 2. I just called Allergan again about a denial letter that requires hours of further research on every penny we spend. My husband suffered a massive stroke with paralysis. I work the entire day on his care. Allergan wants that time spent providing information from cable bill to utilities to food and clothing monthly expenses. I quit. He just won't get the medication, even though Humana Pharmacy doesn't even cover it. That is no assistance for people already suffering."

6 / 10
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  • Anon2d
  • April 10, 2016

For Chronic Idiopathic Constipation "I went to a GI specialist last week, assuming I had some serious issues other than constipation. However, it was just that- chronic constipation. The doctor gave me samples of Linzess and I started it at 10am on an empty stomach. I had a bowl of oatmeal about half an hour later. Then, 20-30 minutes after I had eaten I had the urge to use the rest room and for the first time in years, without the help of several laxitives, I expelled. Three times within a two hour time frame. I don't mind the diarrhea, because it was much worse not being able to go. But it is scary knowing you have to pass gas and not knowing if you might accidentally crap yourself."

8 / 10
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  • Caq
  • Taken for less than 1 month
  • August 23, 2014

For Irritable Bowel Syndrome with Constipation "I started taking Linzess about a week ago and I'm beyond thrilled. I'm 26 and have never been able to go to the bathroom without taking something and even then usually only every two weeks. My first day taking this medication 30 mins. Before my first meal, I had no pain, no cramping, no gurgling etc. And was able to go within 4 hours. My bowel motions are not watery like some describe but actually what a normal bowel motion should be like. There's no after pain and no pain while I am going. I haven't had a sudden urge to go but rather I just go when I try to. Additionally, I have only gone 1-2 times per day and I am so excited about that! This is a miracle medication and I can't wait to see how much healthier my body will be. Thank you for creating this!"

10 / 10
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  • Couldnt...
  • Taken for 1 to 2 years
  • October 26, 2014

For Chronic Idiopathic Constipation "Believe me. If you "cannot go" this will do the trick. I had CAT Scans, Upper GIs, tried Gluten free, Dairy Free, chugged water, EVERYTHING. this has been a life saver. But beware. I am only 24 years old and I sometimes want to wear depends. This stuff gives no warning when you're about to...2."

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  • KOS
  • August 14, 2019

For Chronic Idiopathic Constipation "I've been on Linzess for three years for Chronic Idiopathic Constipation (CIC). Prior to this drug, I could go a week without a bowel movement and when I was finally able to expel what was in my system, I thought I would die from an aneurysm because my stool was so hard. I looked like I was pregnant, not to mention I felt sick to my stomach almost all the time. The first few weeks on the medicine were pretty terrible, the urge to go was overwhelming and I could never be too far from a bathroom. Yes, that immediate urge to go still occurs pretty often, sometimes several times in a three hour time period but I am able to hold it a bit without being uncomfortable. If I am traveling (driving, flying, touring) or if I have an important morning meeting that I don't want to excuse my self from more than once, I will not take my pill. Last month, I went to Europe and didn't take the medicine for five days, which meant I didn't go to the bathroom for five days- that was a far worse feeling than how I feel on the medication."

8 / 10
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  • Gems
  • Taken for 1 to 6 months
  • April 8, 2021

For Chronic Idiopathic Constipation "I’ve been on Linzess for about 5 months now. At first, it was just uncontrollable watery diarrhea. I couldn’t imagine how that would help my IBS with chronic constipation. Now that I have been on it awhile, I can say that I don’t want to be without it. I do still have daily diarrhea with this but, it’s better than chronic constipation. I had a perforated colon, where my colon literally split in half and caused me to be in critical care. I want to avoid a repeat of that at all costs!"

8 / 10
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  • 30...
  • Taken for 1 to 6 months
  • August 9, 2017

For Chronic Idiopathic Constipation "I can't impress upon you how my life has changed . 30 years of fighting constant chronic constipation . I have tried EVERYTHING ! Linzess worked after 3 or 4 hours and it was like the flood gates opening . After using Linzess for 3 months daily I figured I could try taking it every other day but that didn't work . I stayed on it a few more weeks and then the miracle occurred . I weaned myself off of it and it's now going on 6 months that I have not taken ANYTHING for constipation and I wake up every morning and have a well formed BM . I can't remember ever being so regular in my life . I FEEL THAT LINZESS CURED MY CHRONIC CONSTIPATION . My theory is that taking it daily for months wiped out the bad intestinal flora . I've been reborn !"

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.