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Levomilnacipran User Reviews & Ratings (Page 2)

Brand names: Fetzima

Levomilnacipran has an average rating of 5.1 out of 10 from a total of 211 reviews on Drugs.com. 37% of reviewers reported a positive experience, while 44% reported a negative experience.

Reviews for Levomilnacipran

  • Non
  • Taken for less than 1 month
  • January 23, 2019

Fetzima (levomilnacipran) for Depression "Prozac quit after 10 wonderful years. Tried many others. Nothing. Then Fetzima can’t get by 20 mg tablet due to nausea, bloating. Then attack either gallbladder or something else? Severe vomiting. Did fetzima trigger gastrointestinal problems? Hasn’t improved mood either. Going off. What to try next? This is a crazy circle. Hopefully one day there will be something better than “try this, “try that” approach. At 70, ready to give up."

1 / 10
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  • Depre...
  • Taken for less than 1 month
  • April 15, 2016

Fetzima (levomilnacipran) for Major Depressive Disorder "I have an extreme case of depression that very few experience, and I have had extreme depression for over 25 years with pain I cannot begin to describe. In the past, Nefazodone and Cymbalta rescued me and each worked for a decade or more, but they eventually pooped out. None of the SSRIs and other drugs worked for me. I switched from Cymbalta to this drug and within days this drug started working. If you are one of the 10% of depressed people where only norepinephrine antidepressants work for your depressed (SNRIs, Tricyclics) then this is a good drug to try. It is too early to tell if this drug will work long term for me. The side effects of this drug went away within a week for me."

10 / 10
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  • JamJamN
  • February 8, 2018

Fetzima (levomilnacipran) for Depression "I was switched from anxiety medication to Fetzima. I was very nervous at first, not knowing what to expect and reading a million different reviews. From my personal experience, this medication has been amazing. I have been feeling so well. For the first time in years I actually enjoyed Christmas instead of stressing myself out beyond belief. I actually feel like I can cope with family, work and life stresses. I tend to overextend myself and try to go above and beyond for holidays, Birthday ‘s, school functions, etc. I can handle it now without having a breakdown and I know my limitations and have learned it’s ok to reach out to others for help. Medicine reacts differently with everyone but I personally have had such a wonderful experience and am so glad I listened to my doctor and tried this. It has been a success for me."

9 / 10
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Frequently asked questions

  • smili...
  • September 25, 2015

Fetzima (levomilnacipran) for Major Depressive Disorder "I am on day 12 of Fetzima 40 mg and feeling awesome! I've dealt with depression for over 15 years and I've never had a medicine work so quickly. I am also on Abilify 5mg a day. I've been on just about every med out there except MAO's.My advice to you is to keep on until you find the right med for you. There is light at the end of the tunnel!!! My side effects are bad headaches but I will gladly deal with that to finally feel like a normal human being again."

10 / 10
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  • Mrs...
  • May 25, 2017

Fetzima (levomilnacipran) for Major Depressive Disorder "I was 120mg. Was great for my mood, but I had several side effects including: increase blood pressure, tachycardia, urinary hesitation, constipation, bloating, stomach pain, dry mouth, nausea, and UTI. My Dr. told me to choose whether I wanted to feel good mentally or physically. Looking for new Dr. I think I deserve both. one without the other is simply existing,and I want to live life happy and healthy."

1 / 10
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Are you taking this medicine?

  • Bausten
  • Taken for less than 1 month
  • September 27, 2016

Fetzima (levomilnacipran) for Depression "This norepinephrine dominant SNRI has helped tremendously with my depression. It has given me increased energy and focus without sleep disturbance. So far, no significant sexual side effects (will post later if this changes.) Currently at 40 mg; may go up to 80 mg in preparation for seasonal mood worsening. I do believe the medication is also helping me with mild-to-moderate age-related aches and pains. Overall, very satisfied!! PS. No side effects for me; or I'm interpreting the side effects as positive, i.e. increased focus and energy, yet that's what these meds are supposed to do. Maybe someone else might interpret the energy and focus as anxiety."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • January 27, 2017

Fetzima (levomilnacipran) for Depression "Update: I've been on Fetzima 5 months. It has worked better than any of the other 30 meds I've tried. It took 4 months for my arms itching side effect to go away and soreness of my mouth's upper roof and upper gums also is gone. My heat and sweating is almost all gone. If I stay on the couch, I'd have no sweating but when I did anything such as brushing my teeth I'd get so much sweating. Normally I don't sweat. These side effects do go away, so don't give up on this drug too soon. I don't get that drugged out tired feeling from the depression anymore. I do have a little anxiety from Fetzima but it is usually when I'm in bed trying to sleep more when really I had enough sleep which is good because that keeps me from escaping into bed."

10 / 10
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  • Momzee
  • Taken for 1 to 6 months
  • July 8, 2015

Fetzima (levomilnacipran) for Depression "I have had severe depression since my teens and have been on antidepressants for many years. Fortunately I have had beneficial effects from several over the years. The most effective treatment to date has been a combination of Wellbutrin and Cymbalta. I took that combination for ten+ years and unfortunately I recently started slipping downward, increased depression and feeling out of control. I was prescribed Fetzima (transitioned off Cymbalta) and completed the starter pack with the only benefit being increased energy. My Dr then increased the doseage to 80mg and have been at 80mg for two + weeks. I have never felt (for lack of a better word) so crazy in my life! I have been so irretiable, angry, depressed and unreasonable and feeling"

1 / 10
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  • Sagin...
  • November 28, 2016

Fetzima (levomilnacipran) for Depression "This works better than anything I've tried. I was doing well with Strattera for 4 years then it stopped working. I did well on Wellbutrin many years, it stopped working, etc. With Fetzima I get up easily in the morning because I lay in bed for at least 15 minutes, I pet and play with my cat, have quiet time saying things I'm grateful for and sometimes I get guidance for information for my day. I don't overeat anymore, I get full fast, can only eat 1/2 as much as I used to because I get bloated which helps. My headaches went away after 2 months and my sweating is almost gone away now after 3 months. I feel good and motivated to do things. I'm not hyper like with Wellbutrin."

8 / 10
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  • chess
  • October 29, 2015

Fetzima (levomilnacipran) for Depression "Horrible. I have suffered from anxiety and depression for many years. Doctor decided that I would try this medication. I have tried over 30 medications with no results. This medication significantly increased my anxiety. I have social anxiety and normally only become anxious in social situations. When taking this medication I became anxious 24/7 and the anxiety intensity also increased. I felt like I was dying."

1 / 10
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  • Xris-t
  • Taken for 1 to 6 months
  • January 13, 2016

Fetzima (levomilnacipran) for Depression "Took a 6 week trial of fetzima, after trying Zoloft (which I hated) and Celexa (which was ok). Fetzima seemed to work well! No more bouts of crying or crazy attitude. But my blood pressure and heart rate sky rocketed! While exercising my heart rate would increase to 200bpm! Resting could sometimes be 120 bpm! And although the feelings of depression had subsided, I had my heart to worry about. Not worth the overall long term damage to my body..."

6 / 10
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  • Deali...
  • Taken for 1 to 6 months
  • May 27, 2014

Fetzima (levomilnacipran) for Depression "I started Fetzima at the request of my doctor as my mood was very dull and I was using Alcohol to help with anxiety. After 8 weeks at 40 mg I could not handle the excessive sweating that was so bad I was showering sometimes 4 times a day and washing my sheets almost daily. The worst part was the excessive pain after intercourse that would almost bring tears to my eyes from the pain. I have since been moved to another SSRI. "

2 / 10
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  • Chelsea
  • Taken for 6 months to 1 year
  • May 8, 2018

Fetzima (levomilnacipran) for Major Depressive Disorder "My medical history includes migraines, MDD, and insomnia. The medications that I have taken over the last 3 years to treat MDD include Wellbutrin, Effexor, Lamictal, Zoloft, Trazodone, Prozac, Lithium, and Remeron. The medications that I have taken over the past 3 years for insomnia include Ambien, Ambien CR, hydroxyzine pamoate, Remeron, and temazepam. Currently, I am on propranolol (for migraine prevention), rizatriptan (for migraine abortion), lamotrigine, Adderall XR, and Fetzima. By far, Fetzima has been the most successful medication in relieving my depression symptoms and has given me the fewest side effects. I have been taking it for approximately 6 months and have not relapsed as I usually do after 2-3 months on the various other antidepressants I've taken."

10 / 10
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36 Report
  • Squonk
  • Taken for 1 to 6 months
  • May 20, 2014

Fetzima (levomilnacipran) for Depression "Started on 20mg daily and went up to 40mg. Little or no mood changes. Some of the worst side effects I've experienced: Loss of libido, erectile dysfunction and premature ejaculation. Pain with urination. Initial loss of appetite which then seemed to swing the other way and make me want to eat constantly. Very increased irritability, to the point that I caught myself screaming insults at the computer or other drivers (in private, thankfully), pounding my fist on the desk, and having to plug in headphones and crank the music loud enough so that all the little noises around me didn't make me scream in anger."

3 / 10
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  • Capt
  • July 29, 2015

Fetzima (levomilnacipran) for Major Depressive Disorder "I have had MDD for a while along with anxiety. I have tried so many medications, and am medication resistant. Prior to taking Fetzima, I was on Topamax which helped me quite a bit when I was not in a good place. However, it was not helping anymore, so my doc thought maybe going to an SNRI may help. I had mostly been on SSRI's before. The Fetzima really helped me with motivation and getting engaged in my day. I am taking 80 mg right now. I had tried the 120mg, but went back down since I couldn't tell a difference between the two. I have been on Fetzima now for about 4-5 months. I really don't have any side effects. The first week or two, I had a little nausea, but no SE now :). Best Wishes!"

9 / 10
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  • Paisan...
  • Taken for less than 1 month
  • August 28, 2016

Fetzima (levomilnacipran) for Depression "My experience with this medication is terrible. I have moved up to 40 mg daily. I have had a rapid heart beat all day. The mood swings are terrible, running nose, the sweats, body aching, headache and just feel very irritable the dreams are more like nightmares. I am not sure how they still market this drug but I would not recommend this to anyone. It is not an anti depressant but an anti feel good product. I have never written a review before but feel so strong that other people should not get involved in this drug."

1 / 10
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  • Jillb...
  • Taken for 1 to 6 months
  • October 6, 2014

Fetzima (levomilnacipran) for Depression "I've been taking this for almost 2 months. After doing more research I've realized it isn't for me. I feel no worse or better then when I started it. I have post traumatic stress disorder and this doesn't seem to be helping at all."

2 / 10
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  • StacyW
  • May 1, 2014

Fetzima (levomilnacipran) for Major Depressive Disorder "I started Fetzima earlier this year (2014) and I am now going off of it because it just didn't work for me. The one thing it did do for me was give me some energy which I sorely lack. That's why I gave it a "3" because it did do something. But what I really need is something to lift my mood, and this it did not do. The depression is still very bad. My doctor just switched me to Brintellix today. Here's hoping."

3 / 10
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  • asdfg...
  • June 4, 2014

Fetzima (levomilnacipran) for Depression "The potential side effect list became my life. I got everything, the extreme sweating, nausea, dry mouth, constipation... all of it. Had to stop going to my daily kickboxing classes completely because I'd get dizzy and throw up every five minutes until I stopped working out. I had to plan taking it around being able to spend two hours in bed not moving in air conditioning just to keep it down. Saw 0 effect on mood, I was switched to a new one yesterday and hopefully life gets better."

2 / 10
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  • Seve
  • February 12, 2016

Fetzima (levomilnacipran) for Depression "So far (knock on wood) I have not experiences any MAJOR side effects but I plan on checking back here after being on the medication for longer than a week. I have noticed the sweating (not severe though) my doctor did warn me about it before I started taking it. The first day I had a HORRIBLE headache and was dizzy most of the day. It was gone after my first nights sleep on it. I can't make a good or bad judgment on it YET however if in a month I experience any thing else I will check it - well I'll check in here either way because these forums with REAL experiences helped me when I was first introduced to this drug as I had never heard of it before."

8 / 10
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  • ksm
  • June 19, 2014

Fetzima (levomilnacipran) for Depression "I was only able to take it 4 days on day four I got very I'll started as uncontrollable depression then violent vomiting. I proceed with Dr advice to go back to old medicines. I've been off it 2 days. I can't eat without severe stomach pain no matter what I eat."

1 / 10
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  • vegwe...
  • Taken for 6 months to 1 year
  • August 25, 2016

Fetzima (levomilnacipran) for Major Depressive Disorder "This is an update to my comments from March. I am still very happy with it. I did experience itching and sweating initially but those side effects are long gone. I also felt teary and emotional for several months. At first, I thought the Fetzima was providing some pain relief, but , I must have just been having a remission period. I have Psoriatic Arthritis and Fibromyalgia. I do think it is having a wonderful effect on my binge eating disorder. I have lost much of my interest in junk food and sweets. I can occasionally eat these things without going overboard or setting my self up for cravings. I have not lost my appetite, but I have found myself becoming satisfied with less food and have been losing weight without much effort."

10 / 10
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  • TLC
  • Taken for less than 1 month
  • February 22, 2020

Fetzima (levomilnacipran) for Depression "I was taken off my other medications to see if this one would be more effective. I started with the 20mg for 2 days I did feel crummy but I was also taken off the other meds cold turkey so I figured it was from that. Day 3 I started the 40mg and within 30 minutes I just started to feel unwell then got this horrible pressure in my neck and head that continued to get worse. I also became nauseated, shaky, and weak. I called my PCP and she told me that I should probably go to the ER. When I arrived my blood pressure was 184/124 which is normally 100/60. I felt horrible. I was informed that I had a very bad adverse reaction to this medication and should stop immediately. It is 5 days later and my blood pressure is now normal but not 100 percent. This was just my experience, I know that this medication does work well for others and I hope it does that for you, no one deserves to live with depression, anxiety and etc.. it's horrible and I hope you find something that works!!"

1 / 10
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  • Jenni...
  • Taken for 2 to 5 years
  • January 23, 2021

Fetzima (levomilnacipran) for Major Depressive Disorder "I suffer from BPD, MDD, bipolar, anxiety disorder. I have been on every antidepressant known to man. Fetzima was a game changer. It is the only one that works for me. Zero side effects. I am on 120 mg. Combined with Lamictal, my depression is under control, and I finally have a grip on life. So thankful for Fetzima."

10 / 10
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  • AXFL
  • May 2, 2015

Fetzima (levomilnacipran) for Depression "I've been on Fetzima for about 2 months. I've noticed improvement of my mood and general outlook, and have experienced some of the typical and more minor side effects, but the ocular symptoms are most worrisome. After about a month on this med, my lower right eye lid began twitching intermittently. It does so on a regular basis, and now I am experiencing a strange tightening in my eyes and blurred vision. It flares up randomly, and generally my eyes now feel like they're too big for their sockets. Progressive worsening concerns me as does permanent damage to my eyes. My doctor recommended a daily dosage of Magnesium and increased water intake. Unsure if I should continue to try and stabilize the symptoms, or stop all together!"

7 / 10
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40 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.