Leuprolide for Endometriosis User Reviews (Page 3)

• Anonymous
• March 6, 2010

"At first, I really thought the Lupron treatments were worth it, but now that I have made a trip to the Emergency Room. Well, let's just say if you are going to go the route of Lupron, you better be single. This drug takes its toll on the family, not just you. Everyone goes through the mood swings, headaches, blood pressure scares, joint pain, feeling like you are going to pass out. So, no taking your kids to school or sporting events. No joining carpools. Don't get too far away from the restroom, urinating more often is not unusual. The things that are the easiest to handle are the hot flashes, night sweats, and chills."

• Fut...
• April 17, 2013

"I was diagnosed with fibroids twice, an ovarian cyst 8 cm big, and endometriosis. I'm going to take my third dose in two weeks, and I was prescribed this medicine for six months. Pros: after the first injection, no periods! Five months without a period was right up my alley, being I had been bleeding so much for so long, I needed the break. Cons: if you eat salty food or heavy carbs, you feel like you are going to throw up. Hot and cold flashes, sweats, stiff joints, joint pain, headaches, sleeplessness/severe insomnia, dry skin and dry eyes. I could go on, but I'm doing this to rid myself of ongoing bleeding, pain, and infertility. It's worth it to stick it out if it really works, I don't know if it does yet, but I know I'm not bleeding."

• Lal...
• November 5, 2018

"I will say I virtually have no periods and have had maybe 3 endo pain days that don’t come close to what the pain used to be. NOW the side effects are horrid! BUT I’ll take the side effects over the pain in periods. My bones ache, not unbearable, but uncomfortable. The night sweats, bad but bearable. I’m tired lots, but I can function with some caffeinated tea & B12 for energy. Mood swings and little depression/anxiety. It’s not intense depression for me, like nothing that makes me want to harm myself, it’s just more of a dark cloud following you around. So if you have mental “instability” before taking the drugs, make sure you talk to your doctor. I did not lose hair, and my hair did NOT thin/fall out. I did not gain weight. The side effects still make the medicine worth taking because I have no pain or real periods. I get the shot every 3 months (I’m on 9 months) and take a pill that comes in the shot package. The pill is taken daily, shot is every 3 months for me. Good luck!"

• Mic...
• Taken for 1 to 6 months
• June 28, 2017

"The hospital OBGYN decided to give me this while I was receiving treatments to prevent me from bleeding out (I have leukemia) and only told me I would get night sweats and a slight mood swing, and I would not get my period. I had my period for a month and a half straight, causing me to get transfusions almost daily. My bones feel like they're breaking, I went from 115 to 170, I'm constantly about to punch through things or cry uncontrollably, suicidal thoughts shot through the roof, blood pressure dropped, sweating so much, I can't walk much anymore without sharp pain and tiredness, etc. I begged them not to give me it on my second round of chemo, and they still did. Do yourself a favor and don't take this drug."

• Mis...
• July 24, 2009

"I took my first injection 4 days ago, but had a migraine that night. Since then, I have been crying a lot. I can't believe the side effects have hit me so fast. I have abdominal pain as well, but the crying is the worst so far."

• Swe...
• January 6, 2017

"I was diagnosed with stage 1 endometriosis after I had a laparoscopy. My doctor suggested Lupron Depot for six months (2 shots). I have been on Lupron Depot for almost 3 months where it is time to get my second shot. I am almost sure I will not get the second shot. I am in worse pain than I was before the shot, and I have had NONSTOP bleeding. You are not supposed to be bleeding while on Lupron, especially for three months. I have an appointment with my doctor soon about my next step. The medicine is supposed to rid you of pain-but for me, it caused it to worsen. In regards to other side effects such as hot flashes, depression, mood swings, etc., I don't have any of that! Bottom line, I wish I never would have gotten this medicine."

• Anonymous
• Taken for less than 1 month
• October 20, 2012

"I am only one week into the Lupron, and my pain has begun to not ease, but not be as sharp as it was at all times. I can finally breathe and think before the next stabbing pains begin. But about two days ago, I got mood swings. I seem insane, I'm fine, then I'm screaming. I'm only 17, and this is NOT what I need along with the disease. I hope it gets better, for I won't have any friends at the end of the six months."

• CDM...
• December 17, 2016

"I suffer from terrible cramps and fibroids. I do take a low-dose birth control that sometimes barely helps my cramps. I was given the 1 dose a month, 6-month treatment after my GYNO could barely do a vaginal ultrasound for one of my visits, and I had been having a 'period' off and on for over 3 months. The fibroid was so large it obstructed the movement of the wand thingy. I've been on it for 5 months, the 1st month, I still got my awful period and spent my usual $50 on pads and Advil, just as heavy. But by the 2nd month, bye bye Aunt Flo, and it's been pretty okay except for the hot flashes, weight gain, tiredness, and the sore hips, soles, and ankles. The sore hips, soles, and ankles don't hit until the 4th month. The hot flashes just suck!"

• Jen...
• Taken for 6 months to 1 year
• October 20, 2016

"I've been on Lupron for 8 months now. I have very, very painful endo that has put me in the ER at least 50 times in the last 5 years. I tried the depo shot and continuous use of the NuvaRing before this. Nothing has worked, except Lupron. I do suffer hot flashes and a bit of fatigue/joint pain around the time that would be my cycle. The first cycle on the injection was still hell, the second, I could still work! :) My doctor wants me on it for a while, as I'm only 23, and she doesn't want to jump to a hysterectomy just yet. I'm scared to go beyond the recommended year of Lupron, but so far, so good, and it's the only thing that's given my life back. I hope that if you try it, it works for you. Though, we are all different."

• Ste...
• December 21, 2019

"I have stage 4 endometriosis and adenomyosis. Had emergency surgery 3 years ago due to a large endometrioma causing a total blockage of my sigmoid colon. Everyone's reports on here about unbearable pain and severe bleeding-yup, same for me. I've been bleeding nonstop for over a year now. Received my first 1-month dose of Lupron on 11/22/19. The only side effect was a slight uptick in libido the first two weeks during the initial estrogen spike. The last week of the month, I got my period, but the bleeding and pain were much reduced from before. Noticed an improvement in pain during intercourse. I am on the add-back and have had no night sweats, hot flashes, or vaginal dryness. No impact on my mood that I could notice. Received my second dose, the 3-month long dose, yesterday (12/20/19). Can't comment yet on the experience, but I'm sure hoping to stop bleeding entirely and eliminate the pain."

• cra...
• June 10, 2015

"I am very happy I went on Lupron Depot. I am on my 6th month of it, and although the symptoms of hot flashes, night sweats, moodiness, and some weight gain are not fun, it still is VERY worth it. I have been pain-free (when I was in debilitating pain before) and no period, which is nice. Hopefully, I'll be able to get pregnant soon too!"

• Alm...
• November 13, 2011

"I have been receiving Lupron shots since August 2011. December will be shot number five. Within the first two weeks after receiving my first shot, I noticed a huge difference in pain. How awesome! I had been dealing with this pain since 2008. I had exploratory surgery and tried Chinese medicine along with acupuncture and found no relief. Lupron has been the first thing to help me be almost completely pain-free. Will post again after the 6th injection. I had one huge mood swing after my 1st shot and very little hot flashes. I am not craving chocolate as much but have found myself craving milk (I have always been a milk drinker)."

• cak...
• March 2, 2016

"I was diagnosed with endometriosis and polycystic ovaries when I was just 16 years old. I'm now 22, and I've gone through 9 birth control pills and 9 different gynos. I had a laparoscopic surgery when I was 17, which removed scar tissue and large cysts from my ovaries. After the surgery, I was on birth control (Seasonique, which is wonderful for endometriosis), and up until a year ago, I hadn't had many issues with pain. I started to get the pains again, along with bleeding for 3 months on birth control, so I went ahead with Lupron. After reading up on it, I was hesitant but moved forward. It stopped the bleeding, but the pain is still there, and now my joints ache every day, and also depression and suicidal thoughts are always there. Do not do it."

• Can...
• Taken for 1 to 6 months
• September 23, 2020

"Lupron ruined my health. It made me depressed and have suicidal thoughts, which are not normal for me at all. I did not continue after month 4, and unfortunately, because I wanted to stop the medication, my doctor would not see me anymore. Please research the ingredients and side effects before you choose to take Lupron. My doctor told me specifically not to look up the side effects... Not wise!"

• Jen...
• October 6, 2014

"I received my first shot on June 18 and thought I made the biggest mistake of my life after reading several blogs. After a couple of weeks, to my surprise, I felt good. I did have hot flashes, vaginal dryness, and joint pain, but it went away eventually. I had my second shot on Sept 18, I'm currently having hot flashes and joint pain."

• Sha...
• Taken for 6 months to 1 year
• September 20, 2019

"I had severe endometriosis. I had the kind of pain that makes you blackout. I would bleed all over my chair at work. I wear only black or navy pants. So far, I've taken 3 shots, and thankfully I am pain-free. I have no period. But the hot flashes are HORRIBLE. I'm always hot and tired. I don't remember the last time I had a good night's sleep. I've gone as far as putting ice packs on my bed so that I can sleep for a few hours. I've gained about 35 pounds in 9 months, my hair is thinning, I ache all over, my vision has decreased so much, I seem to forget everything if I don't write it down. I think I got the entire list of side effects, however, that pain before taking Lupron? No way! I literally shake when I think about it. I'll try to manage."

• Try...
• Taken for 1 to 2 years
• February 23, 2016

"I took it 8 years ago for fibroids, cysts, and severe endometriosis. I was on Lupron for a year after trying other options. I had hot flashes and joint pain, plus a lot of the other symptoms mentioned. Calcium and vitamin D helped with joint pain. The symptoms remained consistent while I was on the Lupron, however, even with the side effects, the year that I was on Lupron was the best I have ever felt. Finally, no more debilitating pain. I got pregnant after the 6-month weaning off period and had two kids. If endo is an inconvenience for you, maybe not the best drug. If endo is ruining your life, some side effects and symptoms are worth getting your life back. I am on it again and grateful that there is something out there that gives me relief."

• Anonymous
• March 18, 2010

"I just had my 5th shot yesterday. The past few months have been painless in regard to side effects other than night sweats and mood swings. I have not gained any weight, and everything seems pretty normal. Once again, other than the mood swings. These are harsh, and sometimes I feel like another person has taken over my body and thoughts."

• Anonymous
• January 1, 2010

"I did a 6-month treatment of Lupron, and it wasn't that bad. The first couple of months, I experienced migraines and hot flashes. For the remainder of the treatment, I continued to experience the hot flashes, but my mood swings became very uncomfortable for my family, friends, and me. I would one minute be calm and neutral...the next minute I would become mean and hateful. That was never how I was prior to the treatment. However, I completed my treatment in August 2009, and I haven't had any problems with my endometriosis at all. My doctor has now given me the option to either get pregnant or continue with birth control pills until I decide to become pregnant to maintain the endometriosis. I highly recommend this method if you can withstand the side effects."

• Anonymous
• January 22, 2009

"I have taken monthly injections for the past 6 months. I had a very difficult time for the first 6 weeks of treatment, but since then have not had many side effects. I had severe stomach cramping initially, along with migraines and mood swings. As those side effects subsided, the hot flashes began. With the hot flashes came nausea and unpredictable crying fits. My doctor put me on a low dose of Estradiol and Prozac. Within a few days, I was pretty much back to my old self, minus the horrible belly pains. I have to say, overall the good outweighs the bad."

• End...
• August 26, 2015

"Lupron is not for everyone! I must admit I was horrified to try it, but it came to a point I would rather die, so I had nothing to lose. In 2011 and 2012, both 9 months each. Then after treatment was birth control (Levora), high dose. Now, 2015, just started having severe pain uncontrolled by anything else, so started Lupron injection yesterday. This med made me forget I had the disease. I'm not saying there could be long-term issues or anything else. But right now, in this moment, I'm not sick, and every time before, it was a godsend. Hopeful this time will be as smooth as the last couple of times. Good luck."

• Doi...
• December 1, 2016

"During my early 30s, I had 2 laparoscopies and 1 laparotomy for severe endometriosis but had no relief from pain. At 34, I had my 1st Lupron Depot shot. It eliminated my pain completely. The only side effects were hot flashes and irritability. The side effects were exactly what I am experiencing with menopause now at the age of 58. I did not have any joint pain or other side effects. After 6 months of shots, my primary care physician advised that bone loss could result from prolonged treatment, so we stopped treatment. As an alternative, I was put on low-dose birth control pills, which I took every day to stop my periods. Should have done this to begin with! No pain and no side effects!"

• Ei...
• December 7, 2016

"I have endometriosis and adenomyosis, and pain was scary, and I became bedridden some of the days. I had my first Lupron 11.25 mg in June 2016. I am suffering following side effects, but I will continue this medication as pain from endo and adeno is worse than side effects. - Swelling at feet - Weight gain - 6 kg in 6 months - Increased sweating - Hot flash suffered only the first month of this treatment - Fluid retention - Carpal tunnel - Forgetful - Growth of upper lip hair - Slipped disc and compression of the right leg nerves. I am going to take the second injection soon, and after that, I will go for hysterectomy. Btw, I am just 36 :(."

• Anonymous
• November 8, 2009

"I was very pleased with my Lupron experience. I was on a six-month course and found the first three to four months easy. I did experience hot flashes, mood swings, and slight insomnia. My fifth and sixth months were a little more difficult for me. The hot flashes became a little more apparent, the mood swings more frequent, and my face began to break out. To me, that was the worst. Along with the Lupron, I had a laparoscopy 2 months before the medication, and I started acupuncture treatments about a month before beginning Lupron, which really helped with the side effects. My pain levels before medication were unbearable. I could hardly bring myself to get out of bed. I now notice that my pain level is low if I have any at all."

• mom...
• Taken for 1 to 6 months
• June 18, 2015

"I took the shot for 6 months. I had issues that I could tolerate, such as vision change. The injection would shoot pain across my lower back. Well, it's been 8 months since I had a shot. It took me 2 months before my period returned. I recently started experiencing pain in my belly button. Vision was getting worse, mood swings. The end of April, my period was bad, then 2 weeks later, I had another one. I was ready to have everything removed. I had given up hope of having a baby... So, out of the blue, I missed my period, and now I'm 5 weeks PREGNANT!! I wish everyone good luck and hang in there!"