Leuprolide for Endometriosis User Reviews (Page 2)

• EJo...
• Taken for 2 to 5 years
• July 27, 2012

"Six years ago, I experienced severe pain caused by an ovarian cyst and endometriosis. I eventually had my cyst removed, but after a few months, severe pain returned. I was dying of pain most of the time, until I could not tolerate it any longer. In August 2008, I was given Lupron Depot. The first month was a nightmare for me, I thought I was dying because of extreme bleeding. After that one month, my body slowly progressed. For three months, I had a 3.75 mg dose, and after that, I was on 11.25 mg. I am so relieved that it has allowed me to live a normal life. I am pain-free, and fortunately, the side effects were not too extreme. My last shot was in March, and I was supposed to have it last June, but due to the unavailability of my specialist, I am waiting for my next step. So far, I am doing fine."

• Anonymous
• Taken for 1 to 6 months
• April 24, 2015

"I was diagnosed with Stage 4 endometriosis and had major surgery. I was only able to take four of the six shots. The side effects are terrible. I had almost all of them. I took my last shot in March 2015. It has been one month, and I am now experiencing panic and anxiety attacks along with high blood pressure. I am only 37 and gained weight, now weighing 155, and have a blood pressure of 142/103. I have never had high blood pressure until the third month of the shot. I have hot flashes, night sweats, chest pains that sent me to the ER, vaginal discharge, painful intercourse, vomiting the day I got the shot. It has been an awful experience. I am praying that when it gets all out of my system, I will not see any of these side effects anymore."

• Anonymous
• March 26, 2009

"I am on my 2nd shot of Lupron, and I am not liking the new me. Everyone says after the first 6 weeks it gets better. I don't know if I can take anymore or if anyone else can take my mood swings. I am very hormonal, frustrated all the time, and mad about everything. My job and family are suffering. The hot flashes are constant, I am miserable. I don't think I will continue with the other shots."

• bar...
• October 30, 2013

"Feb this year I had an ovarian cyst on my right ovary rupture, it was the size of my 3-year-old's head. When they operated, they found I was covered with endo... ah, finally a reason for my pain for the last 2 years... I have just finished my 6-month course. Endo pain fine, but OMG the side effects, dealt with hourly hot flushes home and at work.. gained 10 kgs (awesome), but the mood swings, REOW!! my poor partner. Lucky he is amazing... no pain yet, but have to wait and see what's next. Maybe Mirena."

• Anonymous
• August 16, 2011

"This is my fourth month into the Lupron cycle. I have endometriosis. Have no period, no pain. I do get some hot flashes and a little weight gain, but that is the least of my problems on the shot. It is the joint pain. It is the worst in the morning when I get out of bed. My hands, legs, and feet are the worst. It is not so bad throughout the day. But when I sit for some time, then get up again, the pain starts all over."

• Ind...
• March 4, 2008

"The shot is not too bad in the butt cheek. My problems were the side effects. I think that the hot flashes are the worst of it. I am on my 5th shot, and now I am going through a lot of mood swings as well."

• Mel...
• September 27, 2018

"I had severe cervical dysplasia requiring a portion of my cervix to be removed, chronic pain, PCOS, and was diagnosed with severe endometriosis following laparoscopic removal of many adhesions from my uterus and scarring of my ovaries. My OB recommended I do six to nine months of Depot Lupron after my laparoscopy to keep the endo at bay and help reduce scarring. I started out with the one-month shot and felt okay, a little achy, and some hot flashes. I went back to get the three-month shot. I was miserable, but my OB really pushed me to keep going with it. I am on my second three-month shot, and I am not me anymore. I am moody, extremely depressed, my bones hurt, I've gained 20 lbs, I'm fatigued, anxious, have insomnia, headaches, and have had horrible gastrointestinal symptoms. It is ruining my marriage. My work performance has suffered. I am foggy and forgetful. Everything is an effort. I will not be getting the last shot and hope this hasn't caused irreversible damage!"

• Anonymous
• April 3, 2012

"I got my first dose a month ago. The main side effects I am experiencing are hot flashes, much decreased appetite (not complaining there), and fatigue. I will take all those any day rather than deal with endometriosis pain. So I am definitely pleased with the Lupron treatment. It's nice to not be in so much pain. I would call off work and stay in bed and cry. So big difference!"

• Alm...
• Taken for 1 to 6 months
• October 30, 2016

"This drug ruined 11 years of my life and continues to do so. I was given no add-back therapy, nor told of any side effects, only the leaflet to read at home AFTER I'd already been given a 3-month Lupron shot and told it would help my excruciating endometriosis pain. After reading the leaflet in its entirety, I immediately called my OB/GYN and asked about add-back, calcium, and lots more questions. I was scared of all side effects listed on the leaflet and wished I had known about them before (I'd have refused) or that I could UNDO the shot! He told me the worst that may happen are a few hot flashes. My pain worsened, I got osteoporosis, lost several teeth, and couldn't walk unassisted for 6 months. THIS IS TRULY A HORRIBLE DRUG!!!"

• Jus...
• Taken for 6 months to 1 year
• May 10, 2017

"Many years of pain - After exploratory surgery and a part of one ovary taken, then laparoscopic 3 times to get rid of the endo, I thought this was going to be my saving grace! It has ruined my life, and I'm talking well over 20 years ago. If I remember correctly, it was a new drug they were trying at the time. Yes, it stopped my period and pain, but literally jumped from 110 to 140 in one month, had a complete breakdown, first time ever in my life breaking a glass table. Depression and anxiety and anger became my life. I reported all symptoms, even the little ones, such as sweating and not sleeping, hot flashes, etc. So not worth the lasting side effects, depression never went away! Don't use this drug, it took my happiness in life -"

• Ban...
• January 20, 2020

"Lupron is a horrible medication. Many medical 'professionals' are not forthcoming with their patients about all the side effects, or the long-term side effects that continue well after Lupron is stopped. They also don't tell you it can kill you or disable your life. This medication sent my life into a tailspin (of course I was lied to-being told all the positive and common things you will find on any site about Lupron). I will never return back to normal, just like so many others. I am now having to go for disability thanks to Lupron and the negligence of the doctor who gave it to me. Do in-depth research! Know your facts! I do not recommend this medication. Not only does it damage your body in many ways, but it's put me into a living nightmare!"

• Kat...
• Taken for 1 to 2 years
• March 8, 2018

"I have been on Lupron for about a year. Last year, I had 6 monthly injections. The pain that I was experiencing before taking Lupron was horrible. Within 3 weeks of being on Lupron, I was pain-free with very minimal side effects. One of them was weight gain. For me, the weight gain was way better than the pain that I was experiencing before! I went off the shot for about 6 months, and the pain returned. The second time around, I received a 3-month injection. The pain got worse the first couple of weeks, then it was gone again. Now I feel like I can live a normal, pain-free life again. Still very minimal side effects. This drug has been a lifesaver for me! I read so many horrible reviews of this drug, but honestly, it's been a huge relief for me!!! I now can function again!"

• Anonymous
• February 18, 2012

"I have been on the Lupron shot now for 5 months. I have had no periods or period-associated pain since the second month. There is some minor pain and irritation at the injection site for a day or two after the shot. I have had pretty intense hot flashes and night sweats, minor joint and muscle pain, but the worst for me has been the massive headaches. I am taking another medication now to help with those. I would still recommend the shot if your endometriosis is severe, the side effects still aren't as bad as the pain I was in before. Trying to hang in there for another 4 months."

• kf7...
• Taken for 1 to 2 years
• July 20, 2012

"I was on Lupron twice for endometriosis. The first time I had hot flashes and headaches, after I got off, they went away. The second time I had the same side effects, except when I got off of Lupron, the headaches did not go away and turned into migraines. Now I have had migraines for 16 years since being off of Lupron. I was never plagued with headaches before Lupron. My doctor said I always had the trigger for migraines and Lupron flipped the switch on. If I knew then what I know now, I would have taken a different approach to treating my endometriosis. Having endometriosis and migraines together was worse. Now I'm in menopause and going through everything to the nth degree."

• jul...
• October 6, 2015

"I've been suffering with very painful menstruation and chronic pelvic spasms for over 20 years. The first time I did Lupron, it was a godsend, finally, I didn't have to plan my life and work around my period. Now I'm on a second round. I'm using the 3-month injection, and I love life. Yes, I have hot flashes, and I can be a bit emotional at times, but I'm not in pain, and that is what I was going for. I'm 42 now, and I'm hoping I can stay on this medication until I'm 50. I would really hate to go back to having to deal with this again."

• Anonymous
• Taken for less than 1 month
• June 9, 2012

"I received my first Lupron shot a couple of weeks ago. In the past two weeks, I have noticed that my pain isn't as bad or as often as it was before the shot. The downside is the mood swings and hot flashes. I thought I had a few weeks before I started experiencing the side effects, but I guess not. I know that the next six months are going to be rough, but the way I see it... I've been suffering for five years already, what is six months of hell to help make it all go away? In my opinion, the Lupron shot is worth it."

• Min...
• Taken for 1 to 6 months
• January 28, 2020

"I had 2 injections of this ruinous, dangerous drug - Lupron! 1. NEVER use if have PMDD or PMS! Thyroid disease. Or serious mental issues after childbirth, aka manic depression. My gracious doctor bypassed all the contraindications!! I have spent the past 26 years in an unimaginable state of severe fear! I was diagnosed with hypothalamus, adrenal, and digestive exhaustion. I had to have food supplements to survive! This drug will ruin your MIND! Get a hysterectomy instead!!! It can't cure endometriosis!!!! Get on bioidentical hormones afterwards! You'll be feeling BETTER WITHOUT a uterus, and be able to go on! PLEASE, PLEASE do NOT let ANYONE talk you into using this brain-altering destroyer! You will NEVER have your full sanity!"

• eab...
• Taken for less than 1 month
• August 11, 2018

"Only a few weeks in, and I already hate this. I’m 19 and was diagnosed with stage 4 endometriosis. My doctor said the Lupron shot is my only option in regard to treatment, before a hysterectomy. I’ve been on birth control for 5 years prior for intense pain, but it didn’t help at all. Two weeks in, my bones hurt, I’m constantly hot and nauseous. Depression, I feel, is on its way. I can’t stop crying, and I feel very sad about life. Which is unlike me, I’m a very positive person. My pain is also more intense than before. I feel very helpless because I don’t want to have a hysterectomy at 19, but I hate this medication already. I don’t know what else to do."

• Me2...
• August 31, 2018

"Took the 3-month Lupron Depot shot just one time. It's now 3 months since I had the shot. My reasons for taking this poison are due to extreme PMDD condition, which I also have endo, but the PMDD outweighs! So all my symptoms since the very first week of the injection have been severe hot flashes, night sweats, more fatigue, whole body aches. Just in the last month, my hair has been falling out! Very dry, thin now - I'm extremely moodier than before. This was the worst thing I've done, and I'm super mad at all these doctors who really have no clue what they're doing to people. We are all their guinea pigs. I went 4 days ago to the doctor, and he put me on Primaire (hormone replacement). I'm waiting in misery to see if this added med helps. So far, the new med has had me in tears every day for no reason, a massive migraine, and overall losing my mind! Never ever take Lupron! Just do an internet search on Lupron victims."

• Lie...
• January 19, 2016

"The side effects have lasted years, and Lupron itself caused depression. And I gained over 40 pounds rapidly within three months after use. It gave me seizures, and I had blackouts on top of the usual side effects. I was hospitalized for three days because of the seizures. Not worth it! I'm still plagued by the ungodly side effects every single day! Worst decision I ever made. Never again!"

• Ste...
• Taken for 1 to 6 months
• October 29, 2015

"My doctor has me on the six-month regimen. I am on my second month and have had to go to the ER five times since getting this injection. I don't recommend this to anyone, I feel ill all the time. Very lethargic, very short of breath, heaviness in the chest, pains in my back, and just overall horrible. I had my right ovary and fallopian tube removed due to severe endometriosis, and the doctor recommended these injections and said I would have no problem, and nobody that she has treated has had any severe side effects, so I guess I get them all. I've missed a lot of work, almost losing my job because I just can't function on a day-to-day basis because of the medication. For any of you considering taking this medication, please don't, it is nothing but toxic."

• KC8...
• April 3, 2016

"I want to share my experience with this drug because I truly believe it's of utter importance. My first BC was Depo Provera. I bled right through this, and yes, it's common for the first year, also lighter periods. But mine never went away, then brown bleeding. I was switched to the implant, for other reasons, and the same problem still occurred. Then I was put on BC pills to control the bleeding process. All in all, I was backing up my uterine wall with more blood every time I had a period. Depo Lupron was injected on Jan 18. I bled out all my old blood in a week. I have not had a period or brown bleeding since. My last shot was given on March 18. So far, 0 breakthrough bleeding. I love Depo Lupron."

• Dan...
• Taken for 1 to 6 months
• April 27, 2012

"2/9/12 I had a full hysterectomy (uterus and cervix removed) due to fibroids. My doctor found endometriosis everywhere. My doctor put me on Lupron about a month after the surgery and I had my second shot on 4/20/12. I got hot flashes right after the first shot, but they are really not that bad. Night sweats are more uncomfortable and my joints and muscles are achy and stiff. However, my mood is pretty terrible. I have no patience for anything and feel pretty grumpy most of the time. My pain is lessening but still present. That said, if I can be rid of most of the pain after the 6-month regimen, it will have been worth it!"

• Anonymous
• December 21, 2011

"I was actually surprised to learn I had stage 4 endometriosis, along with 2 endometriomas and a dermoid cyst. I had always had a poochy gut and severe menstrual cramps since I was 16. I am 27 now and have been pain-free for the last 5 months on Lupron Depot. I had a laparoscopic cystectomy and a laparotomy this year. I did suffer side effects of hot flashes and mood swings, but was prescribed 1 mg estrogen daily, and I'm pretty much normal! In about 6 weeks, I will begin trying to conceive my first child! The Lupron and my doctor have been a blessing!"

• Anonymous
• October 3, 2011

"I started the Lupron at the beginning of the summer, April 2011, to be exact. The only side effect I can say I had trouble with was the hot flashes, but nothing unbearable and usually over pretty quick. The first 3-4 weeks after an injection, I would have issues with vaginal dryness, but again, nothing unbearable. I had no mood swings or crazy headaches, but I have been constantly plagued with headaches since I was a child, so I wouldn't know if this had any effect on those. Overall, it has been a totally bearable experience, and the hot flashes were nothing compared to the pain I had before the Lupron. I would suggest it if your endometriosis is bad enough."