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Letrozole for Female Infertility User Reviews (Page 4)

Brand names: Femara

Reviews for Letrozole

Commonly mentioned side effects
  • Kei...
  • Taken for 1 to 6 months
  • June 30, 2021

"My husband and I have been trying to get pregnant for 3 years! The urologist said he is all good. My OB said we have unexplained infertility. I have periods, I ovulate. Not sure what's happening. This is my 3rd month on letrozole, first time with 5 mg. My LH test says it's high, so I pray it works for us this month. This is so emotionally draining, being discouraged for 3 years."

7 / 10
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  • Kha...
  • Taken for 1 to 6 months
  • August 18, 2019

"Prescribed to take 5 mg of Femara starting days 3-7 of the menstrual cycle. I ended up in the ER about a week later with severe pelvic and abdominal pain. I was told Femara had caused a condition called Ovarian Hyperstimulation Syndrome (OHSS). I developed excessive cysts, which caused fluid to build up in my abdominal cavity! Please be careful with this drug!"

1 / 10
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44 Report
  • Mom...
  • Taken for less than 1 month
  • April 29, 2020

"I used letrozole last month, 5 mg, and shame it didn’t work... the Dr said I must take two pills on day 2 of my periods to day 7... Mara, I’m trying again this month, same dose. I started yesterday... and hoping it works!"

5 / 10
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35 Report

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Frequently asked questions

  • MCa...
  • Taken for 1 to 6 months
  • December 17, 2020

"I had a miscarriage at 8 weeks in October. In November, I started taking 2.5 mg Letrozole day 2-6, no clear sign for O. Now on my second month, took Letrozole day 3-7, had O on cycle day 11. Fingers crossed! Baby dust wishes to all of you."

8 / 10
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  • Anonymous
  • April 8, 2021

"I had an ectopic pregnancy 8 months ago and was told to wait 6 months before trying again. So, after 6 cycles on my 7th cycle of trying again, my follicles didn't mature, and I didn't fall pregnant. This month, my doctor put me on 5 mg letrozole from days 2 to 6. I had a follicle measuring 17 mm on CD 15, but I didn't fall pregnant. This cycle, I was put on 7.5 mg letrozole, so fingers crossed it works this time!!"

5 / 10
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23 Report

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  • pin...
  • Taken for 1 to 6 months
  • October 9, 2024

"I had been on Clomid for 5 cycles, but nothing was happening and had begun to lose hope. I googled the other drug other than Clomid, it said letrozole and it was best for someone with obesity or PCOS. I took it the first month, nothing happened. I didn’t expect anything, though. I expected something to happen at least after 3 cycles. The 2nd cycle came, my period didn’t come on my expected date. I thought letrozole was adjusting to my body. After 6 days, I decided to take a pregnancy test, I got a big POSITIVE. I couldn’t believe after experiencing a miscarriage in 2022 and on TTC for 2 years. Letrozole does work, just be patient and pray too."

10 / 10
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  • Flo...
  • January 6, 2020

"I started at 5 mg letrozole to take days 3-7 of my cycle. My cycles were really long (50-65 days). Did 5 cycles at 5 mg and no pregnancy. Dr. said I was ovulating too late in my cycle, and this was the problem but ordered the HSG, all the tests. She also upped my letrozole dose to 7.5 mg days 3-7 of my cycle. I get bloodwork to check my progesterone (to ensure I’ve ovulated) on CD24, call the clinic the next day for the results, and I have ovulated every cycle, between days 16-19. PLUS I have normal length cycles (26-29 days) after starting the 7.5 mg letrozole! All my other tests were normal, husband's tests normal. This will be my fourth cycle on the 7.5 mg dose-fingers crossed! It does work though, inducing ovulation AND regulating cycles! The only side effects I’ve had, one actually just came on about 2-3 weeks ago (?) and that was the severe joint pain-both knees and both hips. My cramps have also been worse during my period-but that’s been the entire time I’ve been taking it."

8 / 10
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More FAQ

  • Ano...
  • Taken for 6 months to 1 year
  • May 1, 2021

"I was put on letrozole by my fertility specialist as I wasn’t ovulating. I ovulated while on it every month, but didn’t fall pregnant until the 8th month. The only issues between me and my husband were that I wasn’t able to ovulate on my own. So be patient, it may just work for you too!"

10 / 10
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  • Nom...
  • Taken for less than 1 month
  • August 15, 2023

"I was diagnosed with PCOS in May 2023, and I was put on Yaz for 3 months. Then my ob/gyn induced my ovulation with Letrozole Laradex CD5 on a 5mg dose. I am hopeful that I will get pregnant. Sending hopeful dust to all the PCOS warriors. Let's soldier on."

9 / 10
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10 Report
  • Anonymous
  • Taken for 1 to 6 months
  • August 28, 2021

"Success! I took 2.5 mg once a day. Letrozole first round did not get pregnant. Second month, 2.5 mg twice a day, got pregnant!!! Now my son is 2 years old. Now I am trying for baby #2. I did again 2.5 mg first cycle, did not work. Now I am starting 5 mg, hopefully I get my BFP!!"

10 / 10
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  • Ray...
  • April 3, 2021

"I have been trying to conceive for two years now. Last month, my doc placed me on letrozole 2.5 mg. Just started mine, though, today makes it day 6, ending tomorrow for my first cycle. Been having terrible headaches since morning, I guess that's one of the effects. I hope and pray I test positive this month. Baby dust to you all."

8 / 10
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  • Hop...
  • Taken for 1 to 6 months
  • June 8, 2021

"So far, 6 months on letrozole with no success :( Trying to conceive. I have PCOS and am pushing 35... We've been trying for two years now. Started 6 months ago on 2.5 mg of letrozole, and after two cycles, went up to 5 mg. Have an appointment to see about possibly increasing the dose or changing medications. Anyone else take this long on letrozole to get pregnant?"

2 / 10
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  • UTa...
  • February 20, 2021

"I’ve had the first dose (5 mg) of letrozole from days 3-7, no dominant follicles, so the doctor recommends I return next month for another dose. I am encouraged by the positive reviews. I pray that it works the second cycle."

6 / 10
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  • sec...
  • Taken for 1 to 6 months
  • October 15, 2024

"I'm trying to get pregnant for a while, PCOS, polyps, and endometriosis, and I got pregnant on the second cycle. The doctor said it would be a long journey, I was not expecting it too soon. I'm super happy, hope you all get your positive. ♥️"

10 / 10
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  • Ebb...
  • Taken for 1 to 6 months
  • February 18, 2022

"I was diagnosed with PCOS a few years ago, and after trying to conceive for 6 months with no luck, my doctor prescribed letrozole. I took 2 rounds, the first was 2.5 mg, and I did not ovulate due to an ovarian cyst. My second round was 5 mg, and I had two mature follicles on my sonogram. I did ovulate and then found out I was pregnant. I did not have any side effects and would highly recommend it."

10 / 10
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  • MCa...
  • Taken for 1 to 6 months
  • February 22, 2021

"Took 5 mg letrozole day 2 to 6. Got pregnant cycle 4, but pregnancy stopped at 6 weeks, but no signs... so only found that I was miscarrying at 12 weeks (first scan)... :( Started again. 5 mg. My second cycle totally failed as my follicles did not grow beyond 13 mm. Will start cycle 3 next month with letrozole increased to 7.5 mg. Good luck to everyone!"

9 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • January 7, 2020

"I took 2.5 mg Femara last month and went to check my ovulation rate. It shows my progesterone level was very low and seems like I didn’t ovulate at all. My doctor has increased the dose from 2.5 to 5 mg. Not sure whether it will work or not. Hoping for the best!"

1 / 10
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  • Ars...
  • Taken for less than 1 month
  • October 29, 2021

"I am suffering from PCOS. It's been 4 years since my marriage. Last month, I took letrozole 2.5 mg, but it didn't work, and ovulation was very slow. I got very depressed about that, and now I am in my 2nd cycle. The doctor has prescribed letrozole 5 mg. I had ovulation on time, waiting for the 10 DPO to take the test. I am very much scared, I don't know what it will show. Please, ladies, pray for me to get pregnant."

7 / 10
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  • KTa...
  • Taken for less than 1 month
  • April 19, 2018

"I took two 2.5 mg pills at night for cycle days 3-7. I had no side effects the first 3 days. Then, the 4th day, my right knee started hurting when going up and down stairs. It hurts every once in a while, so I thought it was no big deal. Well, now it is unbearable. I can hardly move my knee without pain. It hurts to drive, cross my legs, walk, etc. I have been off this pill for 2 full days, and it is getting worse, not better. Then, this morning, I had a severe headache. Quite possibly the worst one I have ever had. It took all I could do to get out of bed. I also had severe joint pain in my shoulders. I have never had that. I am praying that the pain subsides, or I may not be able to drive/work. The only benefit is that my insurance company (Anthem) covered this pill 100% because it is labeled as breast cancer preventative. This is nice, as fertility drugs are not typically covered."

4 / 10
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  • Hop...
  • Taken for less than 1 month
  • February 8, 2022

"I just started my first cycle of letrozole. Reading all these reviews and everyone is giving me so much hope. I really needed this. I hope that it works out for me. I am happy for everyone who has been successful."

9 / 10
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  • Eli...
  • Taken for 1 to 6 months
  • July 28, 2021

"I tried to conceive for a year and took letrozole 2.5 mg for 3 cycles as recommended by my doctor as a treatment for unexplained infertility. After the 3rd cycle, I got pregnant. I was so excited, but unfortunately, at week 5 and 3 days, I felt intense cramps and started bleeding. I went to the ER and it turns out that I had an ectopic pregnancy that had ruptured and was filling my uterus with blood and had to have an emergency surgery. They had to remove my left fallopian tube because that’s where the embryo was. The doctor said that letrozole increases the risks of ectopic pregnancies, which I didn’t know previously. Please be very careful when trying letrozole and have proper medical supervision. Good luck, everyone."

1 / 10
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  • Pre...
  • May 3, 2022

"Trying to conceive almost 2 years, I don’t ovulate, so was prescribed letrozole 5 mg day 2-6, no ovulation. Currently trying again day 3-7 on 7.5 mg. I hope I get my BFP this month. Sending lots of baby dust my way and to all expectant moms."

8 / 10
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  • Lul...
  • Taken for 6 months to 1 year
  • December 4, 2020

"Went to a fertility doctor. They put me on Letrozole. The first 3 months, I ovulated but didn't become pregnant, so they gave me another 3 months! That didn't work either, so they decided my partner and I need to try Intrauterine Insemination (IUI), which I was excited about, but to get public funding, I had to lose weight. So while I lost the weight, I was given another 3 months of Letrozole (which didn't work either). I'm close to losing all the weight I need to, so I asked for another month to carry on trying while losing the weight. So after 10 months on Letrozole, I'm hoping I can either get pregnant this last round or lose this weight to get the IUI!"

2 / 10
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  • SHA...
  • Taken for 6 months to 1 year
  • March 14, 2020

"I’ve been taking Letrozole since August or September last year to help me get pregnant. I’ve been on the Clear Blue ovulating kits. I got the smiley face January 10th. I had intercourse as soon as I got the smiley face. I took pregnancy tests a month later, still no positive pregnancy test. Hopefully this time works, we’ve been trying 6 and a half years!"

5 / 10
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  • Anonymous
  • Taken for less than 1 month
  • February 24, 2020

"I recently found out I have PCOS. My periods went from regular to none, back to regular, then I started my period twice in one month and didn't stop bleeding heavy for 3 months. I was put on Provera for a year, 21 days a month to help regulate my period. Well, I've been trying to get pregnant for 2 years after my miscarriage. My doctor recently started me on Femara. I just took my first pill, but I'm confused because my periods are light, so I don't know if that will affect anything. Hopefully, I ovulate and my period isn't prolonged!"

7 / 10
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16 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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