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Ixekizumab for Plaque Psoriasis User Reviews (Page 4)

Brand names: Taltz

Ixekizumab has an average rating of 7.4 out of 10 from a total of 110 reviews for the treatment of Plaque Psoriasis. 70% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Ixekizumab

  • DJano
  • Taken for 6 months to 1 year
  • July 9, 2019

Taltz (ixekizumab) "I have had scalp psoriasis for 25 years. I have tried all the topicals, shampoos and two biologics with no success. I tried Taltz and it worked! Unfortunately I started getting side effects of sneezing and nasal congestion at 6 months. Recently had swollen and burning lips. I will have to stop using."

8 / 10
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5 Report
  • Long...
  • Taken for 1 to 6 months
  • July 13, 2017

Taltz (ixekizumab) "I have battled psoriasis for 15 yrs trying nearly every topical & biologic treatment available. The only drug that ever provided me with 100% clear skin was Stelara, but unfortunately it stopped working after 3 years. I have been on Taltz for about 5 months. After my first two injections I experienced a reduction in plaques & itching and that progress remained while I was on the bi-weekly injections although I never cleared up by more than about 40%. As soon as I finished the bi-weekly loading period & had to wait a month in between injections my skin immediately reverted to the level of severity experienced prior to beginning Taltz. No negative side effects but this injection hurts more than Stelara, Humira, Cosyntex, & Enbrel."

2 / 10
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6 Report
  • Radman
  • Taken for 1 to 2 years
  • October 30, 2022

Taltz (ixekizumab) "Started taking Taltz in October 2021 and by Christmas my skin completely clear of psoriasis. My finger nails began clearing up at about 6 months of holes and ripples. One year later and my skin and nails are free of any Psoriasis. I’ve had no side effects from Taltz."

10 / 10
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2 Report

Frequently asked questions

  • Clear...
  • Taken for less than 1 month
  • June 15, 2017

Taltz (ixekizumab) "I tried this drug but had terrible injection site reactions to it. My doctor switched me to Cosentyx and I could not be happier. They have a plan that brings my copay down to $0 and it's not based on income. My skin is basically clear just in time for swimsuit season!!"

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  • Aveng...
  • Taken for 1 to 2 years
  • April 19, 2021

Taltz (ixekizumab) "After 1 year quit working my symptoms now are 5x worse than ever what went from my elbows and shin is now head to toe. I gave up and didn't take it this month. I feel like I've been sick since I started this medicine. And now I've been in bed sick for 5 days. I'm tired all the time. It did work great for like 4 months. But it never did clear up my leg and it started showing behind my ears and on my face. Now my skin just feels like I'm on fire."

6 / 10
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Are you taking this medicine?

  • Aura
  • Taken for 2 to 5 years
  • March 19, 2022

Taltz (ixekizumab) "I have now been on Taltz for ~ 2 years and it has helped me to the point where I have been lucky enough to be able to sometimes completely forget my condition. Before Taltz I tried UVB, methotrexate, cyclosporine, Otezla and Humira. None worked for me at all, with cyclosporine and Otelza giving me lots of side effects. Since about 1-2 months in of using Taltz I have been 100% clear. Zero outbreaks during 2yrs on it. I have not been suffering from any respiratory infections (actually less than rest of the family), but I have noticed I have herpes outbreaks more frequently than I used to (I've only had them twice in 10yrs before Taltz, now ~3-4/year). Injection site pain is really only thing I can complain about, but I'd rather endure that pain once a month and live a psoriasis free life! Based on the reviews and experiences I've read here I might try injecting in the stomach next time, maybe less pain?"

10 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • November 14, 2021

Taltz (ixekizumab) "I starting having my plaque psoriasis about 8 years ago, during my mid 40's. No explanation, just 75% coverage in skin with inverse psoriasis in groin areas that were extremely itching and uncomfortable. Started taking Taltz about 3.5 years ago and was 90% clear within 3 months, even the inverse psoriasis. It did nothing for my psoriatic arthritis though. Unfortunately I lost mmt job and my insurance and the ability to continue treatment. Within 6 months the plaque psoriasis and inverse psoriasis came back with a vengeance, covering 90% of my body and making my joints so painful I could hardly walk. I was finally able to get back on Taltz about a year ago. It has not been nearly as effective this time around. Scalp/ears completely covered and large patches on back, knees and stomach/groin still present. Still have about 30% plaque on body and the inverse psoriasis in my groin areas areas even worse. It seems when I stopped taking it, it no longer was as effective. Help!!"

4 / 10
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More FAQ

  • Jrh
  • Taken for 1 to 2 years
  • April 18, 2023

Taltz (ixekizumab) "I started taking Taltz (80 mg once every 28 days after the initial starter dose) a little over 2 years ago after going off of Stelera. From the very beginning, I had amazing results with my psoriasis clearing up immediately, and absolutely 100% clear of psoriasis for the last two years. About 2 months ago I suddenly started breaking out again with psoriasis. I am not sure why or if there was a trigger that set it off. I see my dermatologist in a couple of weeks and hopefully, she will have answers. I would highly recommend Taltz as I was two years completely free and hopefully, i will be able to continue on Taltz."

10 / 10
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  • From...
  • Taken for 1 to 6 months
  • July 6, 2021

Taltz (ixekizumab) "I was able to control my psoriasis for 6 years on Humira when it stopped working. The dermatologist switched me to Taltz 4 months ago. Initially I thought it was going to work as the first month it appeared to get better, however now three months later I have dealt with thrush I cannot get rid of and a rash all over my shoulders and upper back and chest that is so painful and itchy. Any sunlight now makes my skin crawl and it is in the middle of summer. The plaques are returning at a multiplying rate. The injections are horribly painful. I have a high tolerance for pain (no epidural with either of two pregnancies) and this is awful. Apparently there is a reason why my insurance would not cover this."

1 / 10
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  • Monique
  • December 25, 2017

Taltz (ixekizumab) "Been on the drug for 6 weeks now had upper respiratory problems after 5th injection sinus ear infection and after 6th shot (throat irritations and sinus drainage) took Tylenol and Mucinex & that seemed to work for me. It cleared my skin and scalp but little to none nausea. Only had to pay 5 dollars for my medication after insurance. Over all the medication did work for my plaque psoriasis but still questionable about side effects. I was on Enbrell for years and it almost cleared all my skin but some of my scalp. Enbrell side effects gave me some small boils and small colds (sneezing) after injection. Praying that this works for me; However, if the upper respiratory continues or worsening I will want to change because I can’t deal."

5 / 10
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  • Storm
  • Taken for 1 to 6 months
  • December 27, 2022

Taltz (ixekizumab) "I started Taltz in Aug 2022 with 1st dose as 2 injections which I injected in both legs due to not trusting to inject in my stomach. After 2-3 days my eyes were full of mucus upon waking dry eyes and patches around the eyebrow area psoriasis lesions appeared where I never had before. Also on my legs and areas of back. I was told next injection would work so I do the second single dose, and same thing happened along with extreme itchiness on stomach, back, arms and legs, with same thing happening on my face. I was told "oh the next injection should help" SMH. This is torture for someone who has had this psoriasis for like 3 years on your face and doctors not understanding the fact that your skin is beyond sensitive and ointments and other meds not working. I didn’t get psoriasis until I worked at a hospital and basically forced to accept all vaccines needed to be employed and end up getting psoriasis after about 10-14 days after vaccines and never had skin issues in my life until then !!!"

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 4, 2018

Taltz (ixekizumab) "I've been on Taltz for 4 months now. Just within this last injection seems out of the blue I got many plaque spot showing back up on my arms. Not sure what is going on but now I'm very discouraged since my self esteem was great with no psoriasis. Was on Otezla for two years which worked great but unfortunately the company I work for changed Insurance plans and would no longer cover Otezla."

7 / 10
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  • Wooster
  • Taken for 2 to 5 years
  • November 24, 2020

Taltz (ixekizumab) "Took about 2 years to get on to Taltz because of my insurance. They made me try all the garbage treatments first, none of which worked. Once I got put on Taltz I saw improvement almost immediately. I was pretty much 90% clear after just taking the starter dose. After 2-3 months, I was 100% clear and it’s been that way for at least 5 years. Zero side effects. The drug works, but I laugh at the fact the price is like $7000 an injection without insurance....lol."

10 / 10
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  • Psori...
  • Taken for 1 to 6 months
  • July 8, 2017

Taltz (ixekizumab) "I started Taltz after developing a severe flare up of Psoriasis with Humira( worst medication ever). It has improved my Psoriasis lesions slightly but I have not had a great improvement as others describe, I have been taking it now for 12 week. I have about 50% improvements. I am still hoping it clears my skin but I expected to have better results by now."

6 / 10
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  • Matt
  • Taken for 1 to 2 years
  • January 20, 2022

Taltz (ixekizumab) "Was on another medication (Cosentyx) until insurance shut me down and I switched to Taltz. Both worked really well for my plaque psoriasis, pretty much complete clearance achieved in ~3 months. The only major difference between the two was that the Taltz injection was easily 5x as painful. If Cosentyx was a fly landing on your hand, Taltz was a hornet sting. I suppose it's worth the pain if you have good clearance, but ouch."

8 / 10
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  • Tract...
  • Taken for 1 to 6 months
  • June 9, 2021

Taltz (ixekizumab) "I have been on Taltz for 8 weeks now. I had a double dose at first and then biweekly since. My chronic psoriasis was the worst the doctor had seen me when I got my prescription. I was covered head to toe, except luckily my face and hands don’t really get psoriasis. Anyway after a week on Taltz I was completely clear. It was like magic and made me cry I was so happy. I have never been this clear in 38 years except for short bursts during phototherapy. I did get a bit of an infection down below and felt a little unwell a few weeks into treatment but it has settled. I do have irritation at the injection sites. But all of that is worth being clear. I still can’t believe it was that easy."

10 / 10
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  • Jjj
  • Taken for 1 to 2 years
  • August 18, 2021

Taltz (ixekizumab) "Excellent - skin and joint pain cleared COMPLETELY after a couple weeks. My main problem was the skin but it also helped the joint pain. Side effects were a little nausea at first but you can ask your doctor for some Zofran and that goes away. The injections hurt slightly for a tiny bit but it’s negligible and well worth it. Very easy to use. A big pain to get a covered by insurance for my doctor but I’m so glad they went the extra 9 yards because it really works well"

10 / 10
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  • Lolane
  • August 17, 2021

Taltz (ixekizumab) "I started Taltz after trying Humira and Methotrexate. I have been using Taltz for about 24 weeks if not less. I'm leaning to the lesser part. I have severe psoriasis. It was just on the bottom of my feet and now it's all over me in places I have never had it. I'm 29 years old and in pain. I wake up every night about 3 times trying to calm the itch. I have blisters covering feet and don't know what to do. I'm not sure if the Taltz is working or am I allergic to it. I don't know what to do. Please help."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • December 31, 2020

Taltz (ixekizumab) "I started using Taltz 2 months ago for psoriasis and psoriatic arthritis. Within the first few days I could tell a difference in my joints. Also, my skin cleared up within the first month. Besides Otezla, which I had horrible side effects, Taltz is the only other medication I’ve tried besides topicals. The burn of the injection is pretty bad, but I’ll battle through since the results are amazing!!!"

10 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • February 18, 2024

Taltz (ixekizumab) "I take Taltz for both psoriasis and psoriatic arthritis. I made sure my dermatologist and rheumatologist actually contacted each other so I could be placed on ONE drug to treat both. No way I was going to be on different drugs to treat both autoimmune conditions. Taltz has been good. I am blessed, BUT diet also plays a big part. Limit dairy & gluten. Add in a good brand of fish oil, magnesium, and curcumin. The only negative is the needle for the injection is thick and it hurts to jab my skin, whereas previous injections weren't as painful. As for side effects? Who would know, regular blood tests."

8 / 10
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  • MrPJQ
  • August 15, 2017

"I have been on this drug as part of a trial with my derm for a couple of years now - I had been on about 4 other Psoriasis drug trials - all reduced the symptoms but didn't clear them. The same was apparent initially with this, and then about 18 months into the trial the drug company moved us from monthly to two-weekly doses - the residual Psoriasis was gone within weeks of the dose change. I went from a PASI score in the mid 20s to zero."

10 / 10
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  • Travis
  • Taken for 2 to 5 years
  • November 28, 2023

Taltz (ixekizumab) "It's been a life-changing drug for me. My psoriasis was on my scalp, patches on my body, and under my fingernails. Within a few months of taking Taltz, I've cleared up about 98%. I've been on it now for about three years, with very few side effects. I got sick late last year and it was in my lungs longer than typical colds have been for me, and a side effect of the drug is susceptibility to respiratory infections, so I think that was related. Other than that, though, it's been such a positive thing for me."

10 / 10
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  • Works...
  • Taken for less than 1 month
  • September 9, 2021

Taltz (ixekizumab) "Methotrexate cleared me up quick but began to hurt my kidney’s and liver after two years. Switched to Otezla for 1 year. Never achieved better than 70-80% clarity with Otezla. Although taking a pill sure was nice. Within a week of my first dosage of Taltz, Areas that would not clear up with Otezla, are clearing up fast. Happy so far!"

8 / 10
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  • Rassy
  • Taken for 2 to 5 years
  • March 23, 2024

Taltz (ixekizumab) "I began taking Taltz in April 2019. After 40 years dealing with Psoriasis… creams, ointments, light treatments, coal tar, and other biologics… I was completely clear after about 3 months and remain so today. Minimal side effects. Prescription Assistance is available, if you qualify."

10 / 10
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  • Jay
  • Taken for 2 to 5 years
  • February 28, 2024

Taltz (ixekizumab) "I've had plaque psoriasis since I was 9 years old. At age 30 (currently 35), I started Taltz. Over a 20-year period, doctors tried hundreds of medications, and I've never had a result like I had with Taltz. My entire body was cleared up in 6 weeks, and my joints were feeling better. Not one patch was left on my body. I felt like a normal person for the first time in my life. 5 years later, I'm still on Taltz injections. I'm very grateful every day to have found a medication that really helps."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.