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Imiquimod topical and Fatigue: What Users Say (Page 2)

Brand names: Aldara, Zyclara

Reviews for Imiquimod topical

Commonly mentioned side effects
  • Ano...
  • Taken for less than 1 month
  • August 10, 2021

For Human Papilloma Virus "There’s no doubt this is a powerful cream. But I was definitely misinformed on how to use it. I wish I’d read the reviews on this page sooner. I definitely applied too much... I’ve never been in so much excruciating pain. My vagina is RAW and so, so sore. Can’t walk, can’t sit, can’t sleep, can’t wee without swearing. I’ve also had the worst dizziness/fatigue/shivers/hot sweats. It’s horrendous. I’m going to take a break from it for a bit and try just adding a tiny amount next time. Appreciate everyone else’s reviews/advice as they’ve made me feel much less alone in this x."

9 / 10
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  • Sar...
  • Taken for 1 to 6 months
  • March 20, 2025

For Basal Cell Carcinoma "Diagnosed with BCC on forehead, approx size 1/2 inch circle. Have used Imiquimod 5% cream for 6 weeks, 5 days on, 2 days off. I have had no side effects, I suffer from fatigue anyway, so hard to say if it was any worse. The area did not look inflamed, so I am more concerned that the cream did not work. I used an antibacterial soap to wash the area, rinsed and dried the area, and applied cream with a Q-tip. I will have it checked in a few weeks."

6 / 10
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  • Cha...
  • Taken for less than 1 month
  • August 7, 2021

Imiquimod topical for Human Papilloma Virus "I had genital warts, and my gynecologist said to use Aldara 3 times per week. Let me just say, this cream is not pleasant at all. It causes mild itching and discharge sometimes and gave me a sore, but the worst thing is I experience aches and fatigue. After one week, I thought it was not working, but after 2 weeks, the warts have almost flattened and I can see improvement. My advice is really only use it 3 times per week, a thin layer, the next day just start taking Panadol and continue with it. Try not to mess it up by picking at the warts. It will get better, it is just very unpleasant."

8 / 10
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Frequently asked questions

  • non...
  • September 7, 2015

For Keratosis "Male, 68 yrs old. My AKs are on my forearms only. First week on 5% Aldara with a protocol of 3 times a week with a non-use day in between each application. Side effects are apparent but not onerous. Quite a bit of reddening and some minor scabbing on each chosen AK (unsightly). Some itching (ignored) started after the 2nd application and has gotten somewhat stronger since then. Feeling some minor fatigue in the day (not normal for me), although I cannot say 100% that it can be blamed on the Aldara. Some minor headaches have been noticed at the end of one week. All these effects were known going in and expected. None of the more dramatic side effects have been noticed. I won't give a rating until I've been on Aldara longer."

8 / 10
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  • Reg...
  • January 26, 2021

For Keratosis "This is the second winter using imiquimod cream. Last winter I did the back of my neck, ears, forehead, chin, and the décolletage area of my chest. I got a robust reaction on all areas and good results. Side effects were nasal congestion, low back pain, painful skin where treated, and massive itching. Skin also had weeping and oozing. This winter I started treatment on my entire chest area. Started applications 2/3 times a week. Definitely getting a good reaction with sores developing with moderate weeping/oozing. I’m having flu-like symptoms, fatigue, more nasal congestion, and even more pain and itching than last year. No low back pain. Benadryl helps with itching, and Aquaphor helps with pain and healing. This treatment is not for the faint of heart, so definitely not for everyone. However, it does a great job attacking and getting rid of those precancerous cells."

10 / 10
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  • Anonymous
  • November 3, 2010

Imiquimod topical for Keratosis "After my initial 9 days of Zyclara treatment, I have had to stop using it. The side effects are intense to the point of debilitating."

4 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.