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Imiquimod topical User Reviews & Ratings (Page 5)

Brand names: Aldara, Zyclara

Imiquimod topical has an average rating of 7.0 out of 10 from a total of 445 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Imiquimod topical

  • Anonymous
  • November 23, 2015

Zyclara (imiquimod) for Keratosis "I am a female in my late 60s, and on day 13 of the 1st round of 14. After tomorrow, I will be off 2 weeks, and back on for 2 weeks. I am using it on my temples and forehead. Luckily, I have a lot of hair to cover the red spots that have surfaced on my temples. However, I have had NO flu like symptoms, NO fatigue, NO stomach problems. Nothing.....just a bunch of ugly red spots"

8 / 10
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  • XXX
  • Taken for less than 1 month
  • March 28, 2020

Aldara (imiquimod) for Human Papilloma Virus "In the first week of using this cream I felt no difference, although now I’m in my second week ( I apply mon, wed,Fri for 16 weeks) and I’ve got a sore throat and sneezing, also down there BURNS and ITCHES like anything!! I’ve noticed swelling around the surrounding area of the wart (I only have one) but I have noticed it’s decreasing in size slowly but surely ! To reduce the itchiness, take two showers per day ( no scented shower gels) to keep them clean also if you can don’t wear underwear as the friction can make it more painful. For the pain whilst urinating , take a cup or jug and rinse off with cool water! Although the pain is unbearable sometimes ,try and stick it out. :)"

10 / 10
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  • Anonymous
  • January 19, 2012

Zyclara (imiquimod) for Keratosis "I took Zyclara for the first time a year ago at the age of 34 after my doctor froze off 3 actinic keratosis. Actinic keratosis on my nose is back, also I still have red spots where lesions were during the initial treatment. Doctor says I need another round to finish off the damage and as a last best hope to avoid having to surgically remove the spot on my nose. I have fair skin and tons of sun damage (including 2nd degree burns over 20% of my body). My doctor initially recommended that I take 2 months off for the treatment, this time I will take her advice! I found the treatment too intense to work through due to pain and fatigue. Moisturizing the area with petroleum jelly and a topical anesthetic and antimicrobial (neosporin or polysporin) helped a lot!"

8 / 10
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Frequently asked questions

  • Happy...
  • Taken for less than 1 month
  • December 16, 2016

For Human Papilloma Virus "So, I have to admit I was really surprised when I was diagnosed with HPV. I had had two sexual partners, kept up to date on regular Pap tests, and even received the most recent vaccines against the virus (gardasil 9). But it happened. I found one abnormality inside my vaginal opening. It didn't even really look like a wart, it was so small. But. It wasn't there before. So I went in to see my doctor, and yep. Low-risk Hpv. Prescribed aldara. I was told to apply it daily for one week. After the first four applications it was almost gone! Very happy. But. Because of the location, it chemically burned my skin in nearby areas. Very painful. But it works! I also eat healthy and take vitamins. My boyfriend was incredibly supportive as well."

9 / 10
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  • Anony...
  • Taken for less than 1 month
  • March 16, 2018

Aldara (imiquimod) for Molluscum Contagiosum "Had HORRIFIC effects from taking this. I'm currently in the process of getting a diagnosis for Small Fiber Neuropathy because of this drug. I was in the best health of my life before I started applying it. Within two days, I had burning sensations all over my body. It caused a systemic reaction. I discontinued immediately, but over two years later, I still get painful burning all over my body. Google Aldara and "small fiber neuropathy" and you will see I am not the only one who had this condition triggered by Aldara/imiquimod. This drug is a powerful immuno-modulator that triggers multiple types of immune-mediated cells in the body and causes the body to attack itself. People are getting sick from it and their claims are not being addressed."

1 / 10
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Are you taking this medicine?

  • Mc08
  • June 21, 2015

For Basal Cell Carcinoma "I'm using this for bcc. My areas were small to begin with. I am on week 6 and was instructed to use it 5 times a week. I've used a very small amount and I haven't had severe side effects. My lymph nodes have been swollen a few times. I make sure to wash the areas, let it dry, wash my hands and apply. I have always washed it off 8 hours later. I've also avoided getting in the sun. The areas haven't disappeared yet and I'm not sure what they should look like at this point."

9 / 10
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  • Minerva
  • Taken for 1 to 6 months
  • September 25, 2019

Aldara (imiquimod) for Basal Cell Carcinoma "I am in complete agreement with "Old Ruth". Nothing happened for about 10 days, but when it did, wow! Instead of having one lesion only it turned out that I had them all over my nose. It became swollen, then stretched, then "crusty", and then the whole mess disappeared and has not returned, 5 years now. The biggest drawback is the price! It was on half-prescription when I began, but very shortly thereafter it was taken off prescription (I live in Spain) and reverted to 84 euros. I wouldn't mind except with the little- sachets - you don't seem to be getting much for your money. More recently I have had a similar lesion on my temple. I have been using Diclofenaco partly because it seems to have a good reputation, and partly because it is MUCH cheaper. The jury is still out, but it seems to be having more or less the same effect as the Aldara."

9 / 10
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More FAQ

  • allbe...
  • June 27, 2015

For Human Papilloma Virus "3 weeks ago after seeing my Dr about some weird "bumps" on my vagina I got the devastating news that I have HPV. In tears walking out with my prescription for Aldara I was in too much shock to recall what my DR or pharmacist said about applying this very pricey cream. I came across this site and the more I read the more scared I was to use it. I'm sorry for those that had severe side effects but I think it is important to note how effective and great this medication is and how it can work well if used properly!! I only applied it to the warts, used vasoline around on the healthy parts and took benadryl with it at bedtime. In the morning I was sore swollen and sensitive, however it was tolerable. 3 weeks after using it the warts appear gone!"

10 / 10
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  • K94r
  • February 6, 2015

For Human Papilloma Virus "I started trying with home remedies to get rid of warts (Acv) but saw no results. When I was prescribed imiqumod I was not very diligent about applications but saw some small results. However, I refilled my prescription and began to follow the 3 day a week regimen and after 3 weeks even the largest warts have subsided. There was some intense irritation (reason for the 9 out of 10) but as long as it is only applied where needed and washed well, the results are great!"

9 / 10
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  • 24234...
  • April 9, 2017

For Human Papilloma Virus "Absolutely awful. Reaction to this was so bad I was told I almost 100% had herpes (due to Aldara causing severe blisters). Made it 3 days with this medicine and started to have severe vaginal swelling to the point where I had to sit in a warm bath to urinate or dump a water bottle on myself while going (TMI). Stabbing pains, nausea, could not sleep, rawness like I never knew was possible, missed a week of work because I could not even move after I had stopped using it. Took about 2 weeks, 4 doctors appointments, countless tests for various STIs/STDs for my body to fully recover."

1 / 10
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  • AASSBB
  • January 30, 2018

Aldara (imiquimod) for Basal Cell Carcinoma "Easy to apply. The medication journal makes it easy to track usage and clearly defines “break days”. This is week four. Skin is red and irritated, however very bearable and annoying rather than painful. Other side effects are pretty hard to tolerate. Fatigue is beyond belief and at times debilitating yet unable to sleep. Nausea all the time. Headache at times. Perception seems to be a little distorted. Difficult to tell how much the light headed feeling is coming from fatigue. Joints ache. A little weight gain. I’m irritable due to unbearable fatigue. Dreams at night are emotionally overwhelming and vivid. The effect of alcohol is extremely magnified. I call these my little bottles of hell. That’s how they make me feel. That said, it seems to be working and I’m very interested in seeing the results. Given a choice at this stage, excision would be my preference. That might change by the time I finish treatment. However it would take a lot to endure this again."

3 / 10
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  • Anony...
  • June 30, 2015

For Human Papilloma Virus "To all of you using this drug for your warts, I want you to know that there is a light at the end of the tunnel. Your love life DOES continue... And you should not be worried. 90% of all cases clear up for good within two years, and for those that don't, Aldara is a powerful medication to finish it off (Not a cure!). I had that lasted for three years until finally a doctor prescribed me Aldara on Dec 11, 2011. For the first eight weeks, nothing happened (as is common for male treatment), but my doctor seemed to be disheartened by the lack of progress and opted to have them frozen off. A week later I finished the remaining four weeks of treatment. The affected area was red and painless. My doctor finally told me... "You're cured.""

10 / 10
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  • 40s Mum
  • Taken for less than 1 month
  • August 12, 2016

Aldara (imiquimod) for Human Papilloma Virus "I had 3 HPV near my V opening, went to see my gyne. Had it checked and she gv me a box of Aldara, Probas Omega 3 AEE, Protexin Protect Multi Prebiotic. The doc explained treating HPV (skin tags, warts) must be done both ways, frm inside and outside due to low immune/anti body system inside us. Aldara is for skin app, 3x a week (Mon, Wed, Fri). Apply while lying or sit down - allow it to absorb for a while before sleep at night. 1 sachet perweek. As for the Omega 3 & Protect, 2x a day. On top of that, double up my norm 1000mg VitC and MultiV. All these for 30 days. Aft 2 weeks, it completely gone. Balance of Aldara, will keep if any for future."

9 / 10
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  • Jano
  • Taken for less than 1 month
  • July 19, 2019

For Human Papilloma Virus "Gay Male, 29 years old, anal Warts, Imiquimod 5% worked great for me. I recently discovered some anal warts. I talked to my pcp and we decided to give the imiquimod 5% creme a try after freezing didn't work well. I applied the creme 3 times a week (Mon, Wed, Fri) before bed. Within a week I noticed a huge improvement in the size of the warts. After two weeks, the warts were completely cleared up. (one had been quite large initially) I didn't experience any of the major side effects. Its difficult to contain the creme to just the wart when applying and rubbing it in. I did notice some light itchiness the first week and I did wake up groggy and stuffy. I made sure to take lots of vitamins which seemed to help. Both outbreaks were huge blows to my self confidence, and finding an easy at-home treatment that worked for me was a huge relief."

10 / 10
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  • Smurf...
  • Taken for less than 1 month
  • February 3, 2019

Aldara (imiquimod) for Human Papilloma Virus "Black female aged between 24 and 28. Used Aldara for about 1 month, 3 times a week- Saturday, Tuesday and Thursday and washed it off after 10 hours. The wart was on my perineum area. First week on this medication made the wart increase in size, bummer. However, by the end of the second week, the wart had drastically reduced in size. For the first two weeks, I used a whole sachet for each application (realized later this was some sort of over dosage) and might explain the on and off sore throat I experienced during this time. Reduced my dose for the last two weeks- one sachet for 3 applications. In total, I ended up using 8 sachets from the recommended 12. Keeping the rest in case of any re-occurrence. Strangely enough, I only experienced burning and irritation on the last two weeks when I was using a more reduced dosage. There's also minor discoloration where the wart was."

10 / 10
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  • Lani
  • July 5, 2019

Aldara (imiquimod) for Human Papilloma Virus "I developed genital warts (GW) on my vulva going in my vajay jay. I was prescribed Aldara using it (Mon, Wed and Fri) for 16 weeks at bed time. I noticed change on my seventh application. The end of that third week 95 percent of my warts were gone. And the rest were gone in my 4th week. I am now free from GW but my Doc says I must continue to apply aldara until 16 weeks. I don't have any side effects , only headaches in first three weeks of using Aldara. My Doc also told me to apply vaseline on the skin that isn't affected around the warts before applying Aldara cream on the warts. I found this cream amazing and I am happy. The only thing its that , the cream is bloody expensive."

10 / 10
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  • Happy...
  • December 2, 2015

For Human Papilloma Virus "I was diagnosed with anal HPV last month. This week will be my 5th week on this creme and since last week I noticed my GW are gone! I didn't have serious pain, but there was some redness, itching, and mild pain, but that's how u know it's working. The goal was "irritation" my doctor said. I used it 5x's a week before bedtime for 3 weeks then when it got irritated I went to 3 x's a week. I used the entire packet at each application and rubbed the creme into the wart and surrounding skin. I did get itching about 4 hours after application. In the mornings I washed it off. I'm happy this medicine worked for me. Don't be afraid to try it."

10 / 10
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  • A Guyy
  • November 10, 2015

Aldara (imiquimod) for Human Papilloma Virus "Contracted GW and went to dermatologist who diagnosed them after one before misdiagnosed them. Had them burned (electrocuted off) and frozen. Had to return two weeks later as many more small ones had grown, same treatment again. I was then prescribed Aldara for a month, morning and night for 5 day stints (Mon-Fri). I kept up with this first week but second week I started just doing nights as twice a day seems excessive after reading everyone else's prescriptions. Things look much clearer but I got a blister which healed significantly after taking a break for a few days. This stuff takes a few days to kick in but expect to be pretty red and your scrotum to be sore if you're a guy. I'll repost in a couple weeks when I'm done my treatment."

9 / 10
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  • Esteban...
  • February 13, 2016

Zyclara (imiquimod) for Keratosis "I am on day 11 of a 14 day cycle and the first week I experienced flu like symptoms i.e., achy muscles, fatigue & head aches. My only side effect now is a slight headache. I am using Zyclara on my face (temples, forehead and cheek) and my face is looking pretty ugly right now. It looks like an awful outbreak of acne and is very raw. I have more than a few scabs and a lot of redness where I have been applying the cream. It is very itchy and tender and to be honest, while I am still in the middle of all of this, I have questioned whether I would do it again. I guess it would be better to answer that in a couple of weeks. I have wanted to stop using it but it is like swimming half way across a lake. I think I will be happy in a couple of weeks"

7 / 10
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  • Girl
  • Taken for 1 to 6 months
  • June 28, 2018

Aldara (imiquimod) for Human Papilloma Virus "Aldara works wonders. I used it as prescribed and with in 2 weeks, most of the really large lesions were gone! The only downside to Aldara is the side effects. The itching, swelling and redness around the affected area was almost unbearable! I’m on my 5th week of treatment and honestly, I can’t wait for this to be over"

9 / 10
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  • Caz
  • Taken for 1 to 6 months
  • April 6, 2020

Aldara (imiquimod) for Human Papilloma Virus "I noticed small lumps on the inside of my labia. I went to my gyno who confirmed they were genital warts. My gyno prescribed Aldara cream 2 times a week for 6 weeks. The cream caused intense itching in the area, soreness and ulcers in and around the area. I also had headaches, very fatigued & flu-like symptoms. After the 6 weeks, the warts have gotten somewhat smaller but had not disappeared, as it had somewhat worked I asked my gyno if I could get another dose of the cream. I went through another 6 wks of the medication and finished up about 2 wks ago. Aldara did significantly reduce and clear most of the warts but there is still some of them there and 2 wks after finishing treatment, I felt itchy down there again and noticed warts growing back again. I am sad as I went through so much pain physically and emotionally. I can imagine the treatment does work for some patients so it is worth a try, sadly it just didn't fully work for me."

5 / 10
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  • Anon
  • March 13, 2016

For Human Papilloma Virus "I had about 13 small warts around my anus and opening to the vagina. I was prescribed Aldara (Imiquimod) and told it would fight the virus from within and was better than freezing them off. My doctor had said that it could possibly take up to three months to work. Well, only two applications in and theyre almost gone! I cannot believe they are disappearing so quickly. I had read many horror stories about the side effects, itching, sores, etc. My own experience is that, yes, it does get very itchy ( I resisted the urge to scratch) but that itch lasted for approx. an hour and then dies down. I had no burning sensation but i guess it depends on the individual. Overall, I am thrilled with the product. The expense was worth it."

10 / 10
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  • ConCon
  • February 14, 2017

For Human Papilloma Virus "So I want to help everyone out there who hates the way these things look. So the other day I was looking in a handheld mirror at my warts and started to scratch them. I realized I couldn't feel it when I was touching the wart its self! I then proceeded to pinch off as much of the wart I could grab. It bled a little but I didn't feel any pain! I let the cut heal for a few days then used the cream once and I've never seen better results! THE WHOLE WART IS GONE! I DIDN'T HAVE TO WAIT FOR IT TO SHRINK IN SIZE! Now I do not know if this is safe or recommended but I figured if I went to get them surgically removed then they'd basically do the same thing but with a scalpel and charge me a lot! Good luck and let me know if this works for anyone!"

9 / 10
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  • Ren
  • Taken for 1 to 6 months
  • May 5, 2015

Zyclara (imiquimod) for Keratosis "I noticed a bothersome "pimple" that never healed on my back a few yrs ago. After biopsy the dermatologist diagnosed it as basal cell. She lasered it twice for removal. I noticed another spot on my left shoulder, and 3 more spots on my chest 6 mos ago. I have no insurance so Dr suggested Zyclara cream. My first session was 1 week on, 1 week off, then another on and another off. It brought out more spots (which shocked me) in my cleavage and upper chest area. She put me on a second session of 2 weeks on, 1 week off, 2 weeks on. I just finished that session, and other than the new lesions that appeared from the cream, the original spots are almost gone. I have had no apparent negative side effects while using this cream."

7 / 10
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  • Sara
  • Taken for less than 1 month
  • February 18, 2020

Aldara (imiquimod) for Human Papilloma Virus "I found out I have genital warts and they were pretty much a lot to do any other treatment so the doctors suggested me topical cream. At first I was scared when I read all the reviews first 3 applications I didn’t feel any difference but the day after my third time I started feeling like I had a cold or cough and next day morning I had a hard time peeing as I was burning like anything. I found a trick I started sprinkling water cold water on me before I start peeing that made me not feel 95% of my pain peeing. And in 1 day my burn pain while peeing was gone and I saw 50% of my warts have disappeared I’m still a little sick but I’m happy"

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.