Skip to main content

Imiquimod topical User Reviews & Ratings (Page 2)

Brand names: Aldara, Zyclara

Imiquimod topical has an average rating of 7.0 out of 10 from a total of 445 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Imiquimod topical

  • Vorn
  • Taken for 1 to 6 months
  • June 20, 2016

For Basal Cell Carcinoma "I am using Aladara on 6 sites and would not recommend any more than that. It is about my 4th use of the drug and apart from a slight flu like symptoms when I first started I have suffered no general side effects. I am quite active and still feel energetic enough to run, cycle and play tennis as well as DIY! However the lesions are something else. To give reassurance to anyone using it for the first time the reaction on the skin can be quite alarming BUT is perfectly normal and shows it is working. Do read the leaflet. My neck and behind my ears have reacted severely with heavy scabbing some weeping and painful at night. It is a chore applying and washing off but do persevere. It will all heal within a week of stopping."

Was this helpful?YesNo
59 Report
  • Kel
  • Taken for less than 1 month
  • October 2, 2019

Aldara (imiquimod) for Basal Cell Carcinoma "For 18 months I had a sore on my nose that would bleed scab than disappear, finally I had it checked (I should have known better, have family history of skin cancer) came back as a BCC. I'm now 5 weeks into my use of Aldara. for the first 3 weeks didn't really have any signs of it doing to much well now at week 5, my nose is hard scab like and a lot bigger area than I had thought. I wouldn't say its sore just uncomfortable and itchy at times. I guess once completed and healed time will tell if it completely worked, my doctor gives it an 80% chance and if not, its surgery for me. I hope this isn't all for nothing but feel it has been worth the chance and do feel that it has done its job well, so far so good. I'm in AUS and cost was $50."

Was this helpful?YesNo
39 Report
  • Max...
  • January 23, 2014

Zyclara (imiquimod) for Keratosis "I used Zyclara for 2 months, applying it for a week and then taking a week off. I have to say, it does work. I had many pre-cancer spots on my forehead, face and shoulders, that stayed there for years, despite annual freezing treatments. Zyclara cleared up these spots, and they seem to be gone permanently. As for side effects, it was a terrible experience, but only for the first couple of weeks. Basically, the first week of treatment was Hell, the second week was Heck, and the third and fourth weeks were Gosh and Golly. So, only the first week of treatment was painful. For that first week of treatment, it was like being hit with both a body-aching flu and a sleeping sickness at the same time."

9 / 10
Was this helpful?YesNo
69 Report

Frequently asked questions

  • Anonymous
  • December 8, 2014

Aldara (imiquimod) for Human Papilloma Virus "2 weeks ago I thought my life was over with the diagnosis. My doctor let me know I am not alone and over 70% of people have human papilloma virus, its just a matter of who's body's can fight off the warts developing or not. I have been using Aldara for 2 weeks and have only minor side effects like a slight itching which not sure if just my brain thinking its bad or if it was. Apply to only the spots that need. I almost think those who complain of unreal side effects slathered this on without reading directions. The only other side effect which was odd was the first night I applied my heart rate was 100 beats per minute which was strange. Lesions have shrunk in size ten folds. I'm just super pleased. I feel bad for those who cannot afford Aldara."

10 / 10
Was this helpful?YesNo
61 Report
  • Ordin...
  • December 11, 2019

Aldara (imiquimod) for Human Papilloma Virus "Got HPV . I did quarterly STD checks and nothing came up. I am half circumcised. It all started with a small white head kind of thingie on internal foreskin and my doctor initially said it could be a protruded sebaceous gland. So didn’t pay much attention. After 2 months that became a small cluster about 5 mm length. Thats when my doctor said its penile wart. I was devastated and got into very low mood for days. Almost thinking about this growth all the time. I was prescribed this drug. After five applications the skin got super sore and blisters appeared with pus. Doctor said that means the cream is working. I had to stop for a week or so because of the scary reaction it had. And in addition even though the warts subsided it grew back. I started applying second round and same reaction occurred after third application. Took a break again but this time the warts magically disappeared. Such a great feeling now!!!!"

9 / 10
Was this helpful?YesNo
33 Report

Are you taking this medicine?

  • Suzie
  • January 19, 2021

Aldara (imiquimod) for Human Papilloma Virus "I was diagnosed with vin3 last yr. The cells were becoming cancer. I have now done 2 Aldara courses of 6 weeks each and all the vin3 has totally gone and there are no dodgy cells at all. I applied it 3 times a week at night and left it on for 10 hours. Week 4 I started to get a bit sore on my vulva but nothing major and was bearable. Come week 6 no sores nothing at all but only part of the vin3 had been resolved so hospital told me to carry on with another 6 week cycle. It certainly wasn't as bad as I expected and wanted to do a review so if anyone is like I was and terrified please do try it though. Everyone reacts differently and you might have no reaction or only mild like me. The main issue for me was a continued upset stomach. My hair also snapped a lot and has become dry but the hosp said its how I have reacted. It is a form of chemo so its strong stuff. Its also fantastic as saved me having all my bits mutilated!"

10 / 10
Was this helpful?YesNo
26 Report
  • Paris...
  • Taken for less than 1 month
  • August 15, 2015

Aldara (imiquimod) for Human Papilloma Virus "9/10 rating simply because like all treatments currently available it gets rid of the symptom (warts) not the illness (HPV) I had a bout of genital warts, all spaced all over my genital area (clitoris included.) After having read about the treatment, I was so scared that I did not use it for the first 2 weeks but for me liquid nitrogen was way too painful. Remember; Everybody reacts differently, don't be discouraged. I am very sensitive to pain and have gone through this with no burning sensations, absolute no side-effects aside expected sensitivity and by the first week of use I noticed a considerable difference. Dosage: 3 times/week on alternating days e.g. Monday, Wednesday, Friday for 6-10 hours at night (I left it on for 8-10)"

9 / 10
Was this helpful?YesNo
54 Report

More FAQ

  • Cindy
  • Taken for less than 1 month
  • February 10, 2020

Aldara (imiquimod) for Basal Cell Carcinoma "Aldara usage for BCC gave me severe side effects, hospitalization, systemic penetration to my body. Nearly died. DO NOT use this drug. I was forever changed, at a young age. There are so many better alternatives."

1 / 10
Was this helpful?YesNo
31 Report
  • DavidC
  • April 20, 2015

For Human Papilloma Virus "I was diagnosed with a serious case of anal warts (hpv) and when I say serious, it was really severe! My local GUM clinic first of all gave me daktarin cream to try and loosen the warts first but this really didn't do much, I then used the Aldara 5% cream and it was truly magical! Hurt like hell almost to the point where I had trouble sleeping with the burning sensation but after 2 weeks the warts were significantly reduced and the burning had subsided. It does look like I have a few scars due to how many warts there were but all in all its a lot better! 1 year later and I'm still as smooth as I was before the diagnosis!"

10 / 10
Was this helpful?YesNo
53 Report
  • Be Pa...
  • Taken for 6 months to 1 year
  • March 6, 2017

For Human Papilloma Virus "I never leave reviews but I wanted to for anyone else in my spot and wants sound advice. I had about 10-12 small warts above my penis (pubic hair area) and 3 on the shaft. For the "larger" warts on the shaft, I received liquid nitrogen treatment which did not work well - one returned after a month and it had no impact on the other two. I was also prescribed aldara to be used 5x weekly (M-F). Let me be clear - FOR THE FIRST 6 WEEKS IT DID ABSOLUTELY NOTHING. I was let down but continued to apply it diligently. Finally, on week 7 things started getting red and inflamed. This lasted for 2-3 weeks at which point things began healing and now look FLAWLESS. Highly recommended, but BE PATIENT"

9 / 10
Was this helpful?YesNo
43 Report
  • Anonymous
  • Taken for 1 to 6 months
  • February 13, 2013

Zyclara (imiquimod) for Keratosis "I am on week 5. I first used it on my arms with no result. So I decided to do my forehead. A few spots came out. Now I'm doing my chest area...major sun damage! I'm not going to lie, it itches and burns. If all these spots are pre-cancer cells, then its definitely worth a few weeks of pain and discomfort! I just told my co-workers what I was doing so I didn't feel the need to "cover-up". Actually feels better not to have clothes rub on it. I take Advil for the pain. If only I could go back in time and tell myself to get out of the tanning beds, its not worth it!"

10 / 10
Was this helpful?YesNo
59 Report
  • windf...
  • December 24, 2014

For Basal Cell Carcinoma "Was instructed to use Imiquimod only three times a week for basal cell on my nose. Wait until sores appeared and then resolved. Use for three months. There were no negative side effects and it worked well. I am using cream again on another spot on my face and I believe the cancer has disappeared. Will see Dr. in two weeks."

9 / 10
Was this helpful?YesNo
51 Report
  • Its...
  • Taken for 1 to 6 months
  • May 1, 2020

Aldara (imiquimod) for Human Papilloma Virus "Been using Aldara for almost 4 months, started in early January. Had only 4 warts total under foreskin near penis head (Uncircumcised). 2 went away within the first 2 weeks but 2 stubborn small ones stayed for an extra 3 weeks. Never had any weird symptoms or side effects. Was feeling happy again finally But then 2 weeks after I stopped treatment they all came back. I was devastated. This time they took about 6-7 weeks to disappear. Again no side effects. Didn’t get my hopes up this time, been checking every day multiple times and now they are back again :( but this time I caught them when they were very tiny dots so 2 have disappeared after just 2 applications. Hoping the other 2 go away In the next couple days as well. This has really ruined my life... I see stories of people getting rid of them forever so I’m still hopeful. Praying this to be last time I have to use aldara and they don’t come back ever again."

9 / 10
Was this helpful?YesNo
27 Report
  • roseb...
  • February 4, 2009

For Basal Cell Carcinoma "Applying it once a day every day for five days is easier than I at first thought. Luckily the sites are on my shoulder blade area so I can reach them. Had they been in the middle or lower down I would not be able to apply the cream. After a few days the skin turned to sore welts which crusted. It is uncomfortable sleeping sometimes too. Last week (after two full weeks of treatment) I had to miss a day's application because the sore were too painful. I still have many more weeks to continue and I really want to stop, but I shall persist."

8 / 10
Was this helpful?YesNo
72 Report
  • Lisa
  • April 13, 2018

Aldara (imiquimod) for Basal Cell Carcinoma "I had a small dot on my chest and a penny sized one on my side. The dermatology consultant told me to use aldara on the two areas but only once daily for five days then two day break. Leave on for 8 hours then wash off. She then said she would see me in 4 months. I was a bit surprised she didn't want to see me during treatment but thought the aldara must be good at doing its job. How wrong could I be. Within one week of using it the rest of my chest erupted into large red sores with lots of little red spots all over it. I didn't know if this was normal as nothing much was discussed at appointment. I continued to use the cream but everyday was more and more horrific. The sores were blistering and bleeding and oozing fluid not to mention red raw and itchy. By the end of the second week I could not tolerate any more so I stopped using it and tried to contact the dermatology department which wasn't interested unless I had another referral from my doctor."

1 / 10
Was this helpful?YesNo
35 Report
  • R James
  • Taken for less than 1 month
  • March 14, 2018

Aldara (imiquimod) for Basal Cell Carcinoma "I had a BCC on my ear, and had it treated with radiotheraphy. It came back. I then had it cut out with a skin graft. It came back. I then treated it with Aldara, but for not as long as recommended, and that worked for about 6 months, but it returned about a year ago. The Dr. indicated that the next step was surgery to remove part of my ear. I gave it another good dose for the full recommended term with Aldara, and it/s been clear since then. I believe I should have used Aldara from the start, and avoided radiotheraphy and an operation, plus a lot of cost. I've had no side effects, and have used it on other BCC with no problems."

Was this helpful?YesNo
35 Report
  • Gano
  • Taken for less than 1 month
  • August 7, 2018

Aldara (imiquimod) for Human Papilloma Virus "Day four of using aldara on my genital area I have over 20 genital warts (GW) scattered all over my vagina and few in the entrance of my vagina (size of a pinky fingernail) I've used aldara everyday and this is my fourth day. I started getting side effects on the third day (burning, itching, white vaginal discharge and painful urination) I have a pretty good pain thresh hold hence why I’m using it every day. I noticed today that one GW is getting smaller which was the biggest one on my left labia entrance. I hope this works and will keep you updated."

Was this helpful?YesNo
33 Report
  • Anonymous
  • August 15, 2012

For Basal Cell Carcinoma "Using this for basal call carcinoma treatment. Used it for a couple of small areas initially with little problems. Have been using it on a larger spot now, and have developed quite significant flu like symptoms. Have tried to push through them, but they're getting worse to the point of needing to stop the cream. Extremely fatigued and achy, which is just not me. I work out an hour plus several days a week and am only able to struggle through maybe a half work out. It also caused a lot of redness and sores at the site of use, but I can manage that. The good news is it does seem to work on the basal cells."

7 / 10
Was this helpful?YesNo
56 Report
  • Anonymous
  • February 1, 2015

Aldara (imiquimod) for Human Papilloma Virus "I was prescribed Aldara for internal gw. When I finally found a doctor to acknowledge that they existed internally, they were bad. They almost looked like fingers. I say this to make the point that I had a serious case of them. I was put on Aldara for three times a week until 16 weeks. This was the most painful experience I have ever had in my life. I cried in pain for the first several weeks. The itching was almost unbearable in and of itself. I also got very severe ulcers around the treatment sight. I found it helpful to take an allergy pill for the itching and melatonin to help me to sleep with the pain. All that being said, after 16 weeks my gw problem was 90 percent gone.I was given another month's worth for the last remaining few."

8 / 10
Was this helpful?YesNo
46 Report
  • Sheri...
  • Taken for 1 to 6 months
  • April 6, 2014

For Basal Cell Carcinoma "I first used this on my nose and cheek. I had a pretty strong reaction which caused my eye to swell a little. I checked with the PA and decided to continue the medicine despite the discomfort. Next, I used it on my forehead and chest. I did not have a reaction on the forehead, but had a strong reaction on my chest. By that, I mean, there were lots of red bumps which hurt and were itchy. I will stick with it though. It beats having more surgeries to remove the cancer."

10 / 10
Was this helpful?YesNo
49 Report
  • Lucie
  • July 1, 2020

Aldara (imiquimod) for Human Papilloma Virus "The cream worked amazingly! My warts cleared away within 2 weeks of using the cream. The skin where the warts were is now smooth and wart free. However, it was incredibly painful- cream causes severe skin reactions. For me I developed sores and blisters on my vagina after the first week. When I peed it felt like my skin was on fire because it made contact with the blisters. I found I couldn't sit or walk without being in agony. However I persisted as and by the end of the week it was clear. Some tips ! -aloe vera is your best friend. Apply it as often as you can because it will help with the blisters and irritated skin -when peeing, take a class of cold water and pour it at the same time, or squired bottled water. This really helps with the burning and stinging. Also apply aloe vera after peeing -DONT apply to much cream or leave it on for more than 10 hours. I think lathering the cream on didn't help the severe reactions I was having"

10 / 10
Was this helpful?YesNo
23 Report
  • Htown...
  • Taken for 1 to 6 months
  • June 16, 2017

Aldara (imiquimod) for Human Papilloma Virus "I had a very large cluster of anal warts. I went to two colon rectal specialists. The first one was a male and insisted that the infection and removal of warts could only be treated via surgery which would have costs close to $10,000 dollars. So I got a second a opinion from a female colon rectal specialist who also felt that surgery was the best option. That being said she allowed me to try Aldara first. Let me just say that Aldara is a miracle drug! After 8 weeks of treatment and monitoring with my doctor, 100% of the warts were gone. Even my doctor was floored that Aldara was able to treat even the worst cases of anal warts. She would have had me surgery the next day if it weren't for Aldara. It's been a year with no recurrence"

10 / 10
Was this helpful?YesNo
35 Report
  • Mothe...
  • Taken for 1 to 6 months
  • August 1, 2020

Aldara (imiquimod) for Basal Cell Carcinoma "I started using the Aldara cream on the 29th of June after being diagnosed with a Basal Cell Carcinoma on my nose. It’s now been 5 weeks of use and the area is sore, red, crusty and oozing which is exactly what should be happening. I still have another week of use but so far my doctor has been happy with my progress and said that the worse the area of the cancer cells looks after use, the better."

10 / 10
Was this helpful?YesNo
22 Report
  • Nicki
  • Taken for less than 1 month
  • July 27, 2020

Aldara (imiquimod) for Human Papilloma Virus "I've been using Aldara for just over 3 weeks now. I had genital and anal warts all over. They were in clusters and stuck together. But just after week 1 I could tell a difference. Now I only have a few left but you can barely see them. I'm going for a check up tomorrow but I think I might need some more just to get rid of the extra marks. However I would definitely recommend this to anyone with genital warts! It's not a quick fix but you have to be patience with it. It WILL work and if you are experiencing pain, blisters or swelling it means the cream is working as it's the cells dying to get rid of the wart. So the more pain you're in the better as bad as it sounds. I went through pain, blisters and itching in the first and second week. Not so much now as they are nearly gone."

10 / 10
Was this helpful?YesNo
22 Report
  • Rrale...
  • June 17, 2016

For Basal Cell Carcinoma "I'm starting my second week of six weeks for a spot on my chest. I thought it was an allergic reaction after the first night I took it. My entire chest is covered in red swollen, now crusty welts that are painful. The dr said those are all cancerous cells he couldn't see with the naked eye and it's good that it's bringing them out. Honestly, I don't know if I can make it 6 weeks. The pain is bad, I'm naseauss all day, I have achy muscles and feel tired. I have a high pain tolerance so for me to be so bothered is unusual. I know it's working, too well. I'll try and stick it out, what's my alternative? I also have to wear shirts that cover up to my neck it's so bad."

8 / 10
Was this helpful?YesNo
38 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.