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Hylan g-f 20 User Reviews & Ratings (Page 4)

Brand names: Synvisc, Synvisc-One

Hylan g-f 20 has an average rating of 6.1 out of 10 from a total of 248 reviews on Drugs.com. 54% of reviewers reported a positive experience, while 37% reported a negative experience.

Reviews for Hylan g-f 20

Commonly mentioned side effects
  • Anonymous
  • January 29, 2017

For Osteoarthritis "Not really sure. Had a cortisone shot first, which did nothing. I then tried the Synvisc-One. I really didn't have much pain from the injection. I still have pain, but it's not as bad as it was. It's been about a week and a half since I've gotten it. From what I've read, it may take a month to get full relief. Will report back later."

5 / 10
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28 Report
  • I...
  • June 25, 2017

For Osteoarthritis "I received the Synvisc-One injection 3 months ago, it did not help my pain. It caused me more pain and suffering. I can barely walk or sleep. The back of my knee, after waking up to start my day, I can't bend my knee without extreme pain. A week after the injection, I had started dragging my leg because the pain was unbearable. How can I have this injection removed from my knee? I can't live with this very, very, very bad pain from the Synvisc-One injection. The back and front of my knee is agony."

1 / 10
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27 Report
  • Pau...
  • Taken for 5 to 10 years
  • August 9, 2018

For Osteoarthritis "I have been getting the Synvisc-One shots for years. The first time I had the four shots. After about a month, I was doing great. It lasted about two years. Then my next shot lasted about a year. I went to every six months with the shots, and now I am back to one each year. This medicine is about the best. It works for me. Thanks to my doctor and this medicine, I am able to keep working and living a normal life."

10 / 10
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22 Report
  • MsC...
  • Taken for 1 to 6 months
  • October 25, 2016

For Osteoarthritis "Knee surgery in March for (I was told) severe arthritis and two meniscus tears. The recovery and therapy were awful! My doctor kept giving me cortisone shots, then he suggested the Synvisc. I finished the Synvisc treatments in July, and I STILL have horrible pain daily! I can't sleep through the night without the pain, unable to stand on my own without holding on to something, and every visit to a store, I look for a basket just to have something to hold on to. The surgery was a fail, and all the doctor will say is 'you had extensive arthritis, I had to do a lot of work once I got inside of your knee.' I am no longer able to straighten my knee out, I can't walk straight, which has now thrown my back out of whack! It didn't work!!"

1 / 10
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32 Report
  • Edu...
  • Taken for less than 1 month
  • January 19, 2020

For Osteoarthritis "I had the single-shot Synvisc One injection, and the next day, the pain in my knee decreased 50-60%. The key is to make sure you have an experienced orthopedic surgeon do the injection. If the gel does not get in the joint, not only will it not work, but you may have complications. I will continue the shots until I am ready for a partial knee replacement."

9 / 10
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19 Report

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  • Bus...
  • Taken for less than 1 month
  • June 3, 2017

For Osteoarthritis "I have had one problem since I was 10: patella dislocations. I am 43 and had a partial knee replacement already. They knew that I had not had any surgeries and received the SYNVISC shot. The worst pain ever. Someone had to hold my leg. I could barely stand and limped in horrible pain. My leg has a big bruise and knot where the shot was administered, and the pain had been the same. Praying the pain subsides, but I don't have months to wait for relief. I don't think I'll be getting another. The pain had me crying on the bus ride home, and I have a high pain tolerance."

2 / 10
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  • tuc...
  • Taken for 6 months to 1 year
  • December 10, 2016

For Osteoarthritis "Originally, I had Synvisc-One injection 4/2016, and although it took about 6+ weeks for my knees to feel full benefit, I was pain-free for about 4-5 months. It was great!! (Not everyone experiences the same benefit for the same amount of time, I was told.) I started getting knee pain pretty badly again late August, and by mid-September, I couldn't take the pain, so I got steroid injections in both knees. My insurance only allows 2 Synvisc-One injections per year. By the end of October, the steroid injections had worn off, so I got another Synvisc-One injection in each knee. It's now 6+ weeks later (Dec. 10) and I haven't had much relief to speak of. I'm hopeful in the next 10 days or so I'll feel more relief, but honestly, it's the best medication I've had for my knees."

8 / 10
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26 Report
  • cou...
  • Taken for 1 to 6 months
  • June 14, 2018

For Osteoarthritis "I received 1 shot in my right knee about 2 months ago. I wasn't really in much pain before the shot. I had torn meniscus surgery in the beginning of February and was told this shot would help my arthritis. I have pain in both my knees now, my lower back is in pain. I actually feel worse than I did before the shot. My right knee is swollen a bit, and I went back to the ortho doc, who said I have a little fluid build-up and to keep taking ibuprofen, and if not cleared up in a month, he will remove the fluid. The only explanation I have is these side effects came from the shot and have not helped me one bit. I wonder if anyone else has these side effects."

1 / 10
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23 Report
  • tre...
  • September 26, 2016

For Osteoarthritis "For years, I have been in so much pain in my knees and legs that I can hardly walk and spend most of my time sitting on the couch. My doctor used a numbing spray, and the shots weren't painful. However, by the time I went to bed, both knees were hurting so much I had trouble sleeping. My right knee was bone on bone and hurt the most. Now, both knees hurt just to sit; my bones, muscles, and tendons hurt; I can't straighten my legs. I have to have help to stand up from a sitting position. Walking is agony, so I'm still sitting on the couch, but now I'm in constant pain. There is no relief. My legs hurt at night while I'm sleeping. I am also so tired I can hardly stay awake, and I am extremely nervous and shaky. Getting out of bed is a nightmare."

1 / 10
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  • JDM...
  • March 7, 2017

For Osteoarthritis "I received the Synvisc-One injection in early February in both knees. The injection was extremely painful for one knee. It's a month later, I'm still in pain, especially at bedtime. Lots of pain/stiffness in my calves and behind my knees. Not sure if I would receive another injection. Can surgery be worse?"

5 / 10
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25 Report
  • Car...
  • Taken for 10 years or more
  • May 24, 2023

For Osteoarthritis "I had the three-injection Synvisc 11 years ago with great results. Before the injections, I could barely walk from the pain of moderately severe OA in my right knee. I did a lot of researching and reading reviews and learned the importance of 1) finding a doctor who has lots of experience with knee injections, 2) asking for a pre-lidocaine type shot, 3) VERY importantly - keeping that knee elevated for a full 24 hours after each of the three injections, and for the next few days, do not walk any more than necessary as this allows the injected fluid to stay within the knee and not travel down to the calf muscle. I’m going to go through this process again for both knees soon. I hope to have such amazing success again."

10 / 10
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  • Tex...
  • Taken for less than 1 month
  • August 28, 2018

For Osteoarthritis "55-year-old male with arthritic knee. Had one Synvisc-One injection July 30th, 2018 (lot number 8RSLO11). I was in the hospital with infection 2 days later, with 3 arthroscopic surgeries to clean out infection. I contracted staph aureus bacteria in blood from injection. I can't walk, I have horrible pain, swelling in thighs, myositis (muscle inflammation) due to infection. In hospital 20 days. May not be able to have knee replacement in the future due to this infection."

1 / 10
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20 Report
  • Sta...
  • March 17, 2016

For Osteoarthritis "I have had knee pain and swelling since age 12, it has gradually gotten worse over the years. Especially since I was diagnosed with lupus, SLE, and DLE. In the past year, I have had excruciating pain. I went to the ortho and was diagnosed with avascular necrosis. I have since had surgery to remove some dead bone. The pain got better, then worse again, so I got the shot of Synvisc. It has really, really helped. I am just scared something will change and I will be back on the sidelines of my own life. So much to deal with...."

9 / 10
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  • and...
  • Taken for 2 to 5 years
  • October 1, 2016

For Osteoarthritis "I have had about 4 rounds of both knees with Synvisc-One. I have cortisone shots done at the same time. My Dr. is great. He sprays a cooling spray first, then numbs one side. Does the same to the other side. He then injects cortisone and Synvisc-One with just one needle. Doesn't hurt, really. I always ask for the cooling spray! Lol!! I guess everyone at this office asks for the cooling spray."

10 / 10
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27 Report
  • Pep...
  • October 25, 2016

For Osteoarthritis "Had plica band arthroscopic resection done and had post-op cortisone injections, which only lasted one month. I then went back for Synvisc-One injection, which lasted four months. I'm going back for another injection of Synvisc. It really helps in my case anyway."

9 / 10
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  • Amy...
  • Taken for less than 1 month
  • April 17, 2017

For Osteoarthritis "It's been 3 weeks since my first Synvisc One injection in both knees, left knee unbearable pain since day of injection. Pain in places I didn't have before. Pain behind my knee and down my leg, can't sleep, walk, or barely drive without pain. I am a professional dog walker, and this was supposed to help, not hurt. Will never get again! (I'm 42, severe bone-on-bone arthritis in both knees, have had 4 years of cortisone injections every few months, and take anti-inflammatory prescription daily, have tried physical therapy 3 times.) I guess I will just wait for knee replacements and put my life on hold until then."

2 / 10
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  • Pam...
  • December 29, 2018

For Osteoarthritis "I got the shot the first time, and I had no issues. The second time, I had an adverse reaction. Many people on this thread are saying they had chills, constant pain, they couldn't walk, they couldn't get around, their knee blew up, and soreness. That is enough adverse reactions. You need to go to your doctor and get the fluid drained off, and they have to be aware that you had an adverse reaction. I've been to the doctor twice for that, and it has been extremely painful. Really, I should have got the medicine in three different doses since I have arthritis so bad, but they never really informed me. I had an option, so I always took it one dose. No longer. I learned a lot from this last experience, and I just want to share with you that if you do have any uncomfortable feeling and swelling, pain, and fullness, and any other symptoms I described, that is an adverse reaction. You may see more and more of these, especially if you get it repeatedly, so please be careful and be informed."

8 / 10
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19 Report
  • Sha...
  • Taken for less than 1 month
  • October 25, 2019

For Osteoarthritis "After surgery to repair a tear, 3 years later, I started to have so much pain. I tried cortisone, but it did not last. This time, I tried the Synvisc injection. I was still in a lot of pain until 3 weeks after, and it finally kicked in. Now I can finally take my dogs out walking again. No pain at all from the injection, it just took some time to start working, but worth it."

9 / 10
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  • Gra...
  • Taken for 1 to 6 months
  • August 27, 2016

For Osteoarthritis "I had the Synvisc-One shot in early May, hoping to be able to dance at my granddaughter's wedding. I had been walking 2 miles a day, five times a week before I had the shot. Within 72 hours, I was in horrific pain. I sent my husband out to get a walker. 3 weeks later, I wore a knee brace to the wedding, with a TENS unit beneath it to mask the pain. When I called the doctor, he prescribed pain medication. I didn't get it filled. I will not get hooked on pain meds. I have a friend I taught with who got hooked on pain meds, and it wasn't pretty. Anyway, it is now the end of August, and I still have pain in my knees just sitting in a chair or lying in bed. Wished I had read these reviews before having the shot!"

1 / 10
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  • Anonymous
  • June 24, 2017

For Osteoarthritis "I'm not entirely sure which Synvisc injection I just received in both knees, perhaps Synvisc-One, as the physician said it could provide pain relief for up to 6 months. I was periodically taking Ibuprofen when my knee pain flared up. Anyway, immediately after he injected both knees, they felt much better. I thought maybe there was some type of Novocaine combined with the injection, but I think the pain relief was most likely just the Synvisc. It's now been almost 48 hours since the injections, and I would say my pain reduced dramatically and immediately. I hope it does last for up to 6 months. Your 'mileage' may vary, but I hope it works as well for you as it seems to be doing for me."

9 / 10
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24 Report
  • Lov...
  • Taken for 1 to 6 months
  • September 29, 2016

For Osteoarthritis "I have always been a very active person. But I started to get a bulge around my left knee. Really not painful until I got back into heels. Then it ached. So I stepped down to my sneakers. If I did extreme lifting and carrying cases of water upstairs, that would ache. But I started hearing the grinding of my knee. I made an appointment with the ortho doc, got an MRI done of my knee. I needed a knee replacement! But I wasn't ready yet, even though I am getting up there, I surprise people all the time with what I still do. Got the shots, one in each knee. No big deal. 6 weeks later, I cannot walk, using crutches, in enormous pain. Knees so swollen and hard. Can't bend them. What do I do now?"

1 / 10
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24 Report
  • Cri...
  • January 5, 2017

For Osteoarthritis "The first time I had a Synvisc shot, it worked really well with no side effects. The second time I had a shot in both knees and was in pain, had cramping in my calves, and was pretty miserable for about 2 weeks. Now I have popping in my knees as if the fluid got underneath the kneecap or around that area, so every time I walk, my knees pop, and it drives me crazy. I never had this before I got my last shots, so now not only do I have osteoarthritis due to loss of cartilage, I now have another complication with every step. I don't believe I will have another shot, and I wish there was some sort of compensation for this."

5 / 10
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27 Report
  • Coo...
  • April 3, 2017

For Osteoarthritis "The pain went away for about 2 weeks, and then the pain came back strong. I think the Synvisc One doesn't do what they say it does. There needs to be another form of injection without having to go to the doctor 5 weeks in a row that will last a true six months. This Synvisc One shot was not worth the money that they charge the health insurance and myself."

2 / 10
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23 Report
  • Mac...
  • Taken for 6 months to 1 year
  • December 26, 2019

For Osteoarthritis "For osteoarthritis, my wife is 74, has severe bilateral primary osteoarthritis of knees. She had been on Euflexxa for the past few years. Four months after injection, her pain would get worse. We switched to Synvisc One. The physician's assistant explained that she has to feel for the soft spot adjacent to the kneecap to determine where to properly inject. My wife felt more pressure than she had experienced with the Euflexxa. She felt okay after the injection and was able to walk out of the hospital. After six months, the Synvisc One was still giving her significant relief! She was due for another injection. About two weeks ago, she received her second single injection from the same effective medical professional. We feel fortunate in having a physician's assistant who knows how to properly inject the Synvisc One. She is really happy with the results! It gives us hope that she can avoid a TKR for some time to come!"

10 / 10
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15 Report
  • Bee...
  • Taken for 2 to 5 years
  • May 7, 2019

For Osteoarthritis "Synvisc has worked wonderfully for me with osteoarthritis in my left knee. For me, it lasts over a year and makes me feel more stable in walking and standing. I have a sister who had it, and it did not work for her at all (she also has rheumatoid arthritis in addition to osteoarthritis, though). It seems to have a cumulative effect too, I need the injections less often over time. It has been more than 18 months, and I only now feel like I could use another injection."

10 / 10
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16 Report

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