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Hydrochlorothiazide / lisinopril User Reviews & Ratings (Page 2)

Brand names: Zestoretic

Hydrochlorothiazide / lisinopril has an average rating of 5.5 out of 10 from a total of 78 reviews on Drugs.com. 35% of reviewers reported a positive experience, while 31% reported a negative experience.

Reviews for Hydrochlorothiazide / lisinopril

  • Meano
  • Taken for 2 to 5 years
  • September 15, 2020

For High Blood Pressure "I used lisinopril for approx 4 years with no noticeable negative effects, suddenly I began having severe nausea and lack of energy, I attributed it to the heat at the time. It didn't appear to make a difference what I ate, or drank, it came back up, then I started to feel dizzy upon standing, and noticed an inability to see anything but white fog until the dizziness disappeared. I finally went to the Dr who did blood work. Next morning I was given a diagnosis of end stage renal failure. I was in stage 4. The first thing he did was take me off lisinopril, which he said was the culprit. He then referred me to a nephrologist who confirmed his thought and he started me on Tekturna. Luckily and to his astonishment the kidney disease regressed from stage 4 to stage 2. I am fortunate this drug didn't finish me off, but I now have permanent kidney disease, and can't take anything metabolised through the kidney. Avoid this medication at any cost, it is dangerous"

1 / 10
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21 Report
  • Anonymous
  • January 25, 2012

For High Blood Pressure "I'm 52, my doctor prescribed 20/12.5 twice a day. I alternate dosages...take twice a day 3 times per week then one a day other 4 days. My blood pressure is 104/72. I want to be able to take it only once a day soon! I believe it will happen. What makes this medicine work for me is that I am active by exercising 6 days per week (weight training and cardio 4 days per wk, 1 day kickboxing and 1 day just walking). I believe that if you get plenty of cardio work for heart/blood circulation it will do what it supposed to do without really experiencing all of the bad side effects. The only side effect I experienced is a slight sore throat once in a while."

10 / 10
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52 Report
  • Sick...
  • Taken for 1 to 6 months
  • December 2, 2016

For High Blood Pressure "I started taking Lisinipril October 8th, so almost two months ago. I have developed a dry hacking cough and I am suffering from horrible Charlie horse type leg cramps which keep me awake at night. It also makes me feel sick if I don't have food in my stomach before taking it. I have changed my diet to vegetarian, cut out drinking any caffeine or alcohol. Hopefully this will help improve my bp. Going to my doctor next Saturday and I am going to request to be put on something else!"

1 / 10
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35 Report
  • High...
  • Taken for less than 1 month
  • September 26, 2015

For High Blood Pressure "I was on lisinopril 10 mg for years and years but my BP kept going up. On Monday the Doctor started me on lisinopril 20/25 because my BP was 180/110. This ok the meds Tuesday, Wednesday, and Thursday without problems. Friday I fainted but thought I was sick, Saturday I fainted again 1.5 hours after taking the dose. Don't know if I should drop back down to 10 mg for Sunday and Monday but will be going into the office first thing Monday morning!"

7 / 10
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39 Report
  • Emmit...
  • April 4, 2016

For High Blood Pressure "I was on atenolol for 15 yrs with leg swelling, facial swelling, headaches, joint aches, insomnia, no restful sleep, erratic bp in maybe 1 hr. Switched to lis/hctz 10/12.5 3 yrs ago. The only pill I take. BP steady 125/80. Throat sore, swelling closed, mouth breather, headache 12 hr after taking, tinnitis, dizzy when rising, the began Vertigo, real vertigo. Dr said food allergy, stopped lin/hctz for 3 days = BP high, no tinitis, no dizzy, no headache. 3 days ago had bleeding floater in left eye. This morning Optamologist said lin/hhctz can effect floater and maculer degeneration. Deciding what to do.... lose 50 pounds and get off drug! Or put up with side effects and go blind?"

6 / 10
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37 Report

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  • Jean
  • Taken for 5 to 10 years
  • September 1, 2018

For High Blood Pressure "I was on this first about 8-10 years. It did help blood pressure but just a tad. Had daily diarrhea first thing in the morning, ongoing sinus issues (woke up most mornings with a sinus headache), zero tears, etc. After a sudden onset of several eye floaters in one eye, I did some research and stopped taking it. About a week after stopping, I woke up with my eyes oozing thick fluid. I thought my eyes were leaking ocular fluid. It was tears!!! Eyes floaters considerable lessened after two weeks. Have switched to low dose Losartan. So far, the only effect I've noticed is a slight headache and sleepiness ( so I take it will dinner). However, the last few days, the effects have not occurred at all. Hopefully, Losartan will work better for me."

2 / 10
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28 Report
  • Anonymous
  • November 5, 2009

For High Blood Pressure "I took this medicine for several months. There definitely was a cough, it also affected my sinuses. Then I started developing headaches. I thought it was viral in nature but this continued on for 2 months. Then my hair started to fall out and I stopped taking this medicine. Took several days for it to leave my system and I feel much better without it."

4 / 10
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57 Report
  • FL Gal
  • November 16, 2015

Zestoretic (hydrochlorothiazide / lisinopril) for High Blood Pressure "I have been taking zestoretic 20-25 mg along with norvasc 5 mg for 30 years....brand only as my original doctor prescribed and have never had any more issues with my high blood pressure. The generics released medication more up front than zestoretic brand and I would wake up with severe headaches. Zestoretic along with the norvasc was perfect. My blood pressure is normal and I have no signs of any side effects after all these years...I am now in my 70's. I do have to avoid being out in the hot sun for extended periods of time as it does make me a little dizzy, and I have to drink lots of fluids, but a small price to have my blood pressure under complete control."

10 / 10
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38 Report
  • TCTom...
  • October 7, 2009

Zestoretic (hydrochlorothiazide / lisinopril) for High Blood Pressure "Initially I had to get used to the dizzy feeling after standing up too quickly. I rise slower now. I combat the mild dry mouth and cough by drinking lots of water. The diuretic effect, plus my coffee and water intake in the morning, makes me wish I could move my cubicle into the bathroom. That effect tapers off during the day."

8 / 10
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53 Report
  • Anonymous
  • August 27, 2009

For High Blood Pressure "I've been on this medicine for 3 months and have experienced no adverse effects. My blood pressure was 180/95 and now stays steady at 126/80. It did take a few days to adjust to it, but overall I find it beneficial."

8 / 10
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52 Report
  • schapy
  • November 7, 2010

For High Blood Pressure "Since starting this medicine a year ago blood pressure has been a steady 120/70 almost every time. However I have noticed that if I have a cold I will get a little light headed for about 1-3 hours after taking Lisinopril. But not enough of a problem to slow me down much."

9 / 10
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47 Report
  • Anonymous
  • December 12, 2009

For High Blood Pressure "I was recently switched to Lisinopril 20mg/ HCTZ 12.5 mg from Tekturna HCT because my insurance no longer covered the Tekturna. After 2 months of taking nothing my blood pressure went from 176/104 to 108/68 taking the lisinopril/HCTZ. Very mild side effects i.e an occasional cough but nothing alarming. So, I'm pleased with the switch although I was very irritated about the insurance company's unwillingness to keep me on the Tekturna HCT which worked well for me also."

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46 Report
  • Siamk...
  • July 21, 2017

For High Blood Pressure "Took myself off of the drug because my BP was at pre-hypertension, and I had this constant dry cough. I used to have horrible leg cramps at night....no matter how much water I drank before bed. I never use salt or eat salty foods; the doctor said to eat more bananas. I never made the connection to the cramps and the meds, and my doctor did not, either. Well...I wondered why I haven't had any leg cramps in months, and my boyfriend said "you stopped taking your blood pressure medicine". Duh!"

1 / 10
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25 Report
  • Toodl...
  • Taken for 10 years or more
  • May 7, 2018

For High Blood Pressure "I've taken 10 mg for 20 years. Used to have a (not bothersome) cough; that's gone away. The pharmacist said lisinopril is a very good medicine. My usual BP is 120/75 or so with this dosage. This is the only drug I take; I'm active and my weight is about average. I'm really, really happy with it."

10 / 10
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21 Report
  • Angel
  • Taken for less than 1 month
  • May 4, 2021

For High Blood Pressure "I just started taking it and it makes me feel like I have no energy and it made my reflux acted up I don't like the feeling it is giving me I'm not going to take it anymore I'm used to being active and I can't on this medication and this medication made me have upset belly and I hurt enough without this medication making me hurt worse"

6 / 10
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12 Report
  • Brown...
  • Taken for 5 to 10 years
  • October 27, 2016

For High Blood Pressure "Everyday when I take it I feel sick light headed dizzy my stomach knots up and it is aweful pain I have to lay down for awhile to get over it and after reading all of the reviews on Lisinopril I'm wondering if it ain't been side effects all alone since I've been taking the medication"

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24 Report
  • Chris...
  • Taken for 1 to 6 months
  • June 16, 2015

For High Blood Pressure "was taking benazepril 40mg two times a day. My Dad was taking this so I tried it. Works great. I've found that if I split the dose 20-12.5 in two parts, half in morning and half in evening, it works best. 120/70. NO SIDE EFFECTS."

10 / 10
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26 Report
  • Bam
  • Taken for 10 years or more
  • March 1, 2017

For High Blood Pressure "I have taken lisinopril htz for about 10 years, for the past 3 years I've had pancreatitis once every year but for the last 6 months I have had 3 episodes and finally my Dr looked up side effects and pancreatitis was indeed one of them. Just in case anyone else is having the same problem. My Dr switched me to a different Bp medication, I feel better with the new meds."

8 / 10
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21 Report
  • Ms Hi...
  • September 8, 2017

For High Blood Pressure "I have been taking 20 mgs lisinopril for about a month and it has been somewhat of a nightmare. It is effective at lowering my diastolic bp which is good but I'm also trying to eat foods that would help with my blood pressure that contain potassium and that's where the nightmare begins. I wasn't feeling well and I noticed a lot of discomfort after I ate bananas. Because Lisinopril works by causing the body to retain potassium, my eating potassium rich foods is apparently a negative which doesn't make sense if I'm trying to eat better to lower my blood pressure. I now see why people wind up taking these meds for the rest of their lives. I'm going to stop taking it because of this effect on me."

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  • moone...
  • Taken for 1 to 2 years
  • December 28, 2020

For High Blood Pressure "I have been on lisinopril 20mg for over a year now, it worked at first in lowering my blood pressure, it went from 155/99 down to about 135/80- not too bad, but my BP went back up and so we added hydrochlorothiazide and it dropped..... a lot within 3 days it was at 125/87. So far no side effects, but I have a noticed an increase in muscle cramps, charley horse painful ones. Not sure what to do about the cramping. I'll do some research and see if I need to eat something that will reduce the cramping. My doctor does test me frequently for kidney function, but so far no negative effects on my kidneys."

9 / 10
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10 Report
  • Tru4u
  • Taken for 1 to 6 months
  • May 26, 2020

For High Blood Pressure "I started on this medication because my blood pressure was still high even on amlodipine 5mg. It lowered my blood pressure significantly from the 150s to the 120s but the side affects are painful. I have aching pain on the left side of my chest plus a cough as well as some dizziness when I lay down on my right side. I had to cut my pill in half to minimize these effects but I will let the Dr know on my next visit. I would like to stop it altogether but I worry about rebound hypertension."

7 / 10
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10 Report
  • Tina
  • April 15, 2021

For High Blood Pressure "I'm 61 y.o. and have been taking lisinopril / hydrochlorothiazide ( 20mg / 25mg) for over 10 years for high blood pressure. Over the last 3 years I developed symptoms of neuropathy in both feet, and in the last several months, irregular heartbeat, spikes in blood pressure, and near-constant headaches. I was recently evaluated for vascular problems in feet and lower legs; this was ruled out. However, my foot pain is constant, and sometimes it results in shooting pains up to my knees. For an unknown reason this foot pain often increases right after a meal. I am to undergo heart "stress tests" to be followed with some sort of nerve tests in both feet. If these other tests do not point to any known cause, I will ask my doctor to switch me to another blood pressure medication."

5 / 10
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  • Anonymous
  • Taken for 10 years or more
  • February 18, 2018

For High Blood Pressure "Have been taking Lisinopril HCTZ for many years. It has been effective in controlling my hypertension. Recently my pharmacy switched to Watson Labs brand of Lisinopril HCTZ. The blue pills are thin and concave, about 1 cm in diameter. This shape causes the pill to stick in my throat. It is very difficult to swallow, causing me to choke almost every time. It is the worse possible shape for a pill. I do not normally have difficulty swallowing pills, even much larger ones. I have requested that my pharmacy change brands."

5 / 10
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8 Report
  • Not...
  • Taken for less than 1 month
  • August 18, 2021

For High Blood Pressure "Had adverse effects after first pill of 10/12.5 about hour after first dosage, chest pain/discomfort, trachycardia pain in big toe. I took it @ 9am waiting for it to leave my system, it is a horrible feeling so I won't take again."

1 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • April 6, 2020

For High Blood Pressure "Constant dry cough. Frequent urination throughout the day. My physician increased from 20 mg to 40 mg. Still had side effects. Physician added Losartin and the cough went away but I would feel numbness in my right leg and tingling in my right foot."

7 / 10
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5 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.