Estrace Vaginal Cream for Atrophic Vaginitis User Reviews (Page 3)

• Lul...
• Taken for 1 to 6 months
• April 15, 2021

"I'm 54 years old and a couple years into menopause. I started taking this because intercourse was starting to really hurt. A couple weeks in, sex was comfortable and fun again. But about 6-7 weeks after starting it, I became depressed. I don't know if it's related. I've been gritting my teeth, trying to power through the depressive feelings for 3 weeks now, but it's getting a lot worse. I just put a call into my doc, and I think I'll stop using it. Very sad for me because it worked very well for its prescribed purpose."

• Oka...
• Taken for 1 to 6 months
• February 25, 2016

"I have been taking this to see if it will help with my vaginismus, which is where the vaginal clamps down during any sort of penetration due to a trauma. I think it has helped mildly, but not cured my condition - which is not surprising, since it's mostly mental."

• Ano...
• Taken for 6 months to 1 year
• May 2, 2023

"I have been using a pea-sized amount of generic Estrace since Sept 2022. I have had burning and inflammation. After visiting four different gynecologists, all of whom kept telling me it can't be the Estrace, I finally found a doctor in the next state over who actually listened. A biopsy showed inflammation from irritant contact dermatitis. Heading to a dermatologist this week, hopefully for patch testing. Now awaiting the arrival of compounded estrogen."

• Ano...
• Taken for less than 1 month
• June 25, 2025

"I also am having extreme burning after applying only a pea-sized amount of the Estrace cream. The burning feels like a urinary tract infection, even though it's not. I use it only twice a week. I don't understand how such a small amount of the cream can cause so much burning and pain and inflammation. Dr. tells me to keep using it and the issues should subside, but I don't know. I am 69 years old and had a complete hysterectomy 25 years ago."

• Anonymous
• Taken for 2 to 5 years
• June 25, 2013

"Soreness is gone. It makes me feel like a new woman again. And I have no side effects that I know of from it. But it is expensive."

• Anonymous
• March 11, 2010

"I am 59, and it got to the point that I was avoiding sex. I had pain with intercourse and had to use lubricant all the time. I use 4mg once a week and am enjoying sex for the first time in years."

• Anonymous
• February 11, 2011

"I am 54 years old and have been using the Estrace Vaginal Cream for two months. It has improved my vaginal dryness considerably."

• San...
• March 8, 2020

"Had vaginal dryness. I am 65. Tried estradiol cream, it is the worst burning. It feels like a UTI, and I go to the bathroom every 2 or 3 hours. Will never use again."

• Ang...
• April 30, 2015

"RootsGal, they generally say it takes 3-6 months to have full effects. It takes time to rebuild the vaginal tissues."

• BKG...
• Taken for 2 to 5 years
• June 6, 2016

"It has improved my sex life and also eliminated UTIs. I use it once or twice a week. I also use Vaseline daily after each shower."

• Boo...
• Taken for 5 to 10 years
• June 21, 2019

"I have been using this cream for years (had a total hysterectomy in 2001) and went off oral estrogen about 10 years ago. This cream is a miracle. Just wish it were not so expensive."

• Hat...
• December 24, 2016

"Activating the Pay No More Than $25 card did not result in the product being $25. False advertising. Did not purchase."

• Dox...
• Taken for less than 1 month
• December 23, 2019

"After 2 doses of 2 gm, I had the same effect both times: immediate increase in heart rate and slight nausea. Will probably not continue."

• Tri...
• October 18, 2017

"I have tried to use it several times in the last few weeks. After each application, I have burning. I am going to quit!!"