Estradiol topical User Reviews & Ratings (Page 2)

• calin...
• Taken for 6 months to 1 year
• November 17, 2020

Imvexxy (estradiol) for Dyspareunia "I have been using Imvexxy for 6 months. I use the 10mcg one time per week. I would be fine using the 4 mcg twice per week, but it is easier to use the 10 mcg once per week. One minor side effect I noticed is that sometimes I get a slight pelvic cramping a couple of hours after I insert it. It usually does not last more than a few minutes. Other than that, so far it is working for me. I am finally able to resume intercourse with no issues. Everything feels like it was before menopause. I spent a lot of money on the Mona Lisa touch prior to using Imvexxy and it did not work at all."

• Anonymous
• October 20, 2017

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "Help! Can anybody who has had burning after using this horrible creme tell me how long does the burning last? Anyway how do you stop the burning? I put it in once and have been burning for 24 hours... any way to stop the burn??"

• MoBass
• Taken for 5 to 10 years
• March 17, 2019

Vagifem (estradiol) for Atrophic Vaginitis "I had painful sex, vaginal bleeding, thrush for years due to a very early hysterectomy. I've been using Vagifem for seven years now and my life has completely turned around. I was first prescribed its use in the UK every time I had vaginal bleeding but a wonderful gynae in South Africa told me that I should be on small doses for the rest of my life."

• brody
• Taken for less than 1 month
• December 31, 2019

Vagifem (estradiol) for Atrophic Vaginitis "Beware, ladies! I was reassured by my GP that topical oestrogen like Vagifem is so weak and mild it rarely causes side effects. But after taking Vagifem nightly for two weeks I started having dizzy spells. I took my own blood pressure and it was 153/85. Normally it is 121/74! I stopped taking the pills immediately, but 6 days later my blood pressure is still high and I am just hoping it goes down soon. This may be an uncommon side effect, I don't know, but the warning about strokes got me worried."

• Lea
• Taken for 6 months to 1 year
• November 13, 2020

Imvexxy (estradiol) for Atrophic Vaginitis "I have been taking Imvexxy 10mg twice a week for about 10 months now. I had dryness on the outside of my personal area, more so then the inside dryness. I'm 64 with a healthy sex life. My husband thought it made me too lubricated and he didn't care for it. After two months I noticed night sweats, and some hair loss along with slight headaches. Mostly the night sweats was my big problem. I adjusted to 1 time a week of the 10mcg for a month, but still had night sweats. Now, I have been totally off Imvexxy for two weeks and noticed the night sweats have lightened up a bit. I am going to continue to stay off for 6 weeks to see if there is a big difference with the night sweats, hoping they disappear completely. I did not have this problem before I was on Imvexxy. The reason I was checking out these reviews was to see if anyone else had these same side effects, please let me know if you do."

• kappin
• March 31, 2014

Vagifem (estradiol) for Atrophic Vaginitis "Vagifem truly changed my life. Intercourse was almost impossible for me before my doctor prescribed Vagifem. Intercourse felt like knives in my vagina and my tissues were so dry,raw, and painful that I was in constant pain. I have been using it now for about a month and the difference is unbelievable. No more pain or irritation. No side effects so far."

• Blondie
• Taken for 1 to 2 years
• June 2, 2019

Vagifem (estradiol) for Atrophic Vaginitis "Got prescribed Vagifem about 18 months ago and original hair loss was minimal. Had used this on and off in that time. More hair loss. Ouch. Used or started again a month ago. Experienced major hair loss and now have half as much as I used to. Scalp is visible in lots of areas. Will never use again and can only hope that hair will return."

• S Jean
• Taken for 5 to 10 years
• June 18, 2016

Vagifem (estradiol) for Atrophic Vaginitis "I had been using vagifem for about 8 years and now have uterine cancer. I am having a hysterectomy next week as a result. When my cancer surgeon found out I was using vagifem tabs he immediately had me stop it."

• InPain
• Taken for less than 1 month
• September 28, 2019

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "I am 53 and had a complete hysterectomy 27 years ago and have been taking oral Premarin. Dr. Put me on the Estradiol patch which gave me headaches so we just stopped all HRT. Few weeks later I developed a UTI and had extreme vaginal and urethra pain. Was put on Estradiol Cream which irritated all of my skin, so they switched me to Estradiol vaginal tablets. I have been using it for 10 days and I am burning, aching and it feels like something is stuck in me. I do not like this cream and am wondering if the Premarin cream would work better. I keep wondering if this pain will ever go way. Has anyone had symptoms for over 10 days while using the cream?"

• His...
• November 15, 2015

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "I was experiencing very painful intercourse with tearing. I have used this medication exactly 3 times it has improved sex 99% already. Some pain on insurtion, but none during intercourse for the first time in years! I have no doubt it will get better as my body's estrogen levels improve.. So thankful. I am 55 yrs old."

• Obser...
• Taken for 5 to 10 years
• June 17, 2020

Vagifem (estradiol) for Atrophic Vaginitis "Rectal wall bulging problem. Used Vagifem for many years and a couple of years in, started to suffer from repeated internal rectal wall bulges that caused major discomfort and required ligation via rubber banding by a Colorectal doctor every time - around 10 times. The rectal wall bulges kept recurring and I also experienced pressure in the lower abdomen when pressing down to pee. Stopped Vagifem over a year ago - have not had one single rectal wall bulge since!! I believe that Vagifem caused tissue, muscle and structural changes where it should not have."

• GoGirl
• February 17, 2014

Vagifem (estradiol) for Atrophic Vaginitis "No side effects and saw an immediate improvement, as well as a more peaceful state of mind, which may or may not be in my head, but I don't care. I felt great taking this medication, and it helped with the painful entry/sex that I was experiencing. Now, no problems!"

• Westw...
• November 7, 2018

Yuvafem (estradiol) for Atrophic Vaginitis "I am a post-menopausal physician who began using Vagifem in 2011 after a total hysterectomy. I had absolutely no problems with Vagifem. It helped with my urogenital symptoms, such as dryness and urinary frequency. When Yuvafem came out, I was also changed to it via my mail-in pharmacy. I started experiencing a significant increase in vaginal irritation, vulvar dryness, and urinary frequency. I had been having vaginal discharge the day after I inserted the tablet with increased irritation and itching. I never had any significant discharge or irritation when using Vagifem. My symptoms got so bad that at the end of September I went back on brand-name Vagifem. My symptoms have been gradually improving. Given my experience, and the fact that so many others on this site and elsewhere have had a similar issues, I contacted the FDA. I also complained to them in regards to the poor packaging. I feel Yuvafem needs further investigation."

• Dcano
• March 22, 2021

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "I felt like I had a UTI for several months and was losing sleep due to the sensation of needing to urinate constantly. There were also lots of BV and yeast infections so it was frustrating. I found an official OBGYN who was a God send. I’m replying early on with this medicine because after a few days all of the old symptoms were gone. Into it a bit over a week and feel normal again. When I started it I think I was so dried out that my skin could not even absorb this internally as I’d see it the next morning (I assume it was the cream), but even with that - it has helped and I hope they don’t stop prescribing. Quality of life and comfort is important for mood stabilization etc. No point in living to be 100 if it’s painful everyday. Love this cream."

• Gal
• Taken for 1 to 2 years
• August 18, 2020

Vagifem (estradiol) for Atrophic Vaginitis "I am in my late 60's and for the past few years have suffered at least 6-7 urinary tract infections a year. The urologist suggested using Vagifem as directed and apart from headaches and nausea for the first few days have not had any problems and my urinary tract infections have dropped significantly to 1-2 a year. I now only use it once a week and find this sufficient for keeping everything comfortable. I live in the UK so my prescriptions are free. I will continue using it for as long as my general practitioner is happy to prescribe it."

• Relief...
• Taken for less than 1 month
• November 4, 2019

Imvexxy (estradiol) for Atrophic Vaginitis "I can't believe how quickly this worked for me. I am using the 10mcg, and I noticed a big difference after one use. I never realized how bad my situation was until I realized I was moist and comfortable down there the morning after the first dose. (Sorry if that is TMI!) I was having terrible burning, itching, painful intercourse, and a feeling that I always had to urinate. I'm 47 and still menstruating, but my gynecologist recommended this drug. I haven't been using it for very long, but so far so good. I read the full insert and read two books (Estrogen Matters and The Estrogen Window) before deciding to take the plunge. I am still worried about the possibility of hair loss. Some users mentioned that side effect. For the record, I also have RA and secondary Sjogren's Syndrome. I take a lot of immunosuppressant drugs. I hate to add to the medication list, but I was absolutely miserable and getting frequent UTIs from the dryness."

• Linda
• Taken for 5 to 10 years
• March 30, 2019

Vagifem (estradiol) for Atrophic Vaginitis "For those that may not be aware, you can purchase a 3 month supply of Vagifem through Canadian pharmacies for approximately $55. Have been using this approach for years and have never had a problem. If the cost of Vagifem is a problem for you, do yourself a favor and explore this alternative."

• Leyaleo
• Taken for 1 to 6 months
• June 9, 2014

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "At 46, I began having UTI's, urinary frequency/urgency, and burning vaginal dryness. I was prescribed Estrace, but the standard formula caused me burning as well. However, a compounded version of estradiol in a hypoallergenic formula has been very helpful. My vaginal burning has stopped, and the urinary urgency/frequency has improved dramatically over the last 2+ months. I think Estrace can be very helpful, and if you're sensitive to it (the propylene glycol can be an irritant), a compounded version can be extremely helpful."

• Msano
• Taken for less than 1 month
• October 14, 2020

Vagifem (estradiol) for Atrophic Vaginitis "I’m 60 years old and have had multiple urinary tract infectionS over the years. My doctor just started me on the Vagifem 3 weeks ago as well as Progestrone oral tablets. In the last week the burning, itching and irritation is driving me crazy. I’m trying to deal with it and applying topical OTC creams as well as natural balms to try and calm my vagina area down. I’m going back to the doctor tomorrow as I can’t stand this any more. I was really hoping this medication would work for me, I wonder what the next step will be?"

• Pob
• Taken for 5 to 10 years
• October 16, 2020

Vagifem (estradiol) for Atrophic Vaginitis "I have been on low dose (10mg) Vagifem for the past 9 years at least, I have always tolerated it well, but recently have experienced feelings of discomfort and I wonder if the manufacturing process of the pessary has changed?."

• Tenne...
• Taken for less than 1 month
• May 15, 2014

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "I'm 48 years old, and my Doctor has recently prescribed me Estrace Vaginal Creme because intercourse was becoming unbearable. Very painful and I was tearing! Geez! So far, the vaginal pain and dryness seems to be decreasing, as I've been only using the creme for the past month. I have no side effects at all so far. That's a good thing! However, I do find the creme very expensive!"

• menop...
• August 10, 2018

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "This cream has been a miracle. I had a hysterectomy 20 years ago and have been off estrogens for at least 15 years. About five years ago started having all kinds of vaginal discomfort. I think I was also battling a bacterial infection. Tried everything for that too. Finally settled on using boric acid capsules once a week for quite some time and the estrace three times a week. I used about 1gram. After several months finally I was able to stop the boric acid. I also was able to cut my estrace back to once a week 1gram. Before using this I was so sensitive that I would be burning and itching just from wiping with toilet paper. The tissue was so thin it looked shrivelled up down there. I noticed I had what appeared to be blood blisters on my labia which have gone away. The skin has plumped up too and is so much healthier. I would give this a ten except the cost is ridiculous."

• Bub
• Taken for 2 to 5 years
• October 15, 2018

Vagifem (estradiol) for Atrophic Urethritis "Changed my life , was out of my mind with pain and cystitis constantly , never thought for one minute would get any improvement , but vagifem has helped immensely, but if I stop using them I go back to square one , so my gynaecologist said I need them for life , so pray they never stop producing them ."

• nurth
• Taken for 2 to 5 years
• August 30, 2020

Yuvafem (estradiol) for Atrophic Urethritis "I used Vagifem for years & the only issue was occasional yeast infections at the beginning but the drug was effective for Vaginal Atrophy. Years later in an HMO that will only prescribe generics so forced to use Yuvafem. Initially it seemed okay but in the last 3 months I noticed symptoms of burning, itching and UTI returned. Simultaneously, I just read that Teva, the current generic manufacturer of Yuvafem that I'm using, has been indicted by U.S. Federal prosecutors for drug price-fixing along with other drug manufacturers. While they are only under investigation for price fixing, I hope the FDA is also investigating these companies to determine whether they are interfering with the drug formulation, i.e., cutting with fillers. Caveat emptor - while Vagifem is costly, we may be throwing money down the drain with generics that have filler instead of the drug."

• debza...
• December 15, 2008

Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis "I'm a 56 year old postmenopausal woman. I've been postmenopausal for 4 years and have been using Estrace for the last 2 years. I use a minimal amount (2mg once a week). This has greatly helped with my vaginal dryness, as well as keeping the hot flashes in check (a surprising, yet unexpected side benefit). I have had no bad side effects I am aware of. Prior to using Estrace I was taking 2 or 3 oral hormones (with some side-effects), plus I was paranoid about the cancer risk with those. I discontinued the oral hormones and tried using NO hormones for about 6 weeks and couldn't stand it, so my doctor prescribed Estrace."