Spravato for Depression User Reviews (Page 3)
Reviews for Spravato
- NRo...
- Taken for 1 to 6 months
- August 29, 2025
"I’m so glad to be finally doing this. I used Spravato administered by a psychiatrist. It was exactly like an LSD trip. I’ve taken it 40 years before when I was about 20. It was awful. I did six treatments, I thought I was gonna go nuts. It did not help the depression at all. It was a waste of my time, and I hope it didn’t hurt my brain. It’s a scary substance, a very scary substance. I wouldn’t recommend it to my worst enemy. Thank you for listening."
- Art...
- Taken for 1 to 6 months
- July 16, 2024
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Frequently asked questions
- STO...
- Taken for less than 1 month
- March 8, 2019
"I am astonished that this made FDA approval. In the emergency room, I was unknowingly given ketamine IV last fall, and as it was being dripped, I screamed for the RN with, 'What is that!!!' When he said, 'Ketamine,' I said, 'Get it out of me!' I was told it was to 'reset my brain,' and I was not at all interested in that."
- Anonymous
- Taken for 6 months to 1 year
- December 27, 2019
"Depressed no more. Thanks, Spravato."
- Bru...
- Taken for 1 to 6 months
- January 24, 2020
"Really helped. IV is better, but this bridges the gap."
- Sti...
- Taken for 1 to 6 months
- September 24, 2019
"Have been on Spravato for over a month now and developing headaches. My anxiety level is through the roof. Still sad but not crying. Going in for assessment tomorrow."
- Dep...
- January 7, 2023
"Spravato worked when nothing else did. My doctor wanted to prescribe another SSRI, but I heard about Spravato as adjunctive treatment."
- 777...
- October 15, 2019
"Anybody have increased suicidal thoughts on Spravato?"
- Jul...
- Taken for less than 1 month
- August 10, 2021
"Just had my first treatment. I shouldn’t have been anxious, it was a calm, relaxing experience."
- Guy...
- Taken for less than 1 month
- November 12, 2021
"Works great, helps with depression and leaves me feeling wonderful."
- Sti...
- Taken for 1 to 6 months
- August 3, 2021
"Part of a clinical trial for treatment-resistant depression without any other antidepressants. I have 2 treatments left, and it hasn't worked at all and has made my accompanying anxiety worse!"
- San...
- Taken for 1 to 6 months
- June 27, 2019
"I'm on Spravato, and the 56 mg dose is too much. Sick for 4 days after. Then 1 or 2 OK days. Where are all the other reviews? Doctors know all that I know. They are no help at all."
- Alb...
- Taken for 1 to 6 months
- March 7, 2022
"8 treatments at 28 mg, last two treatments felt terrible during and 3 days after, can't sleep and feel sick. Went up to 54 mg, sickly past 4 days, can't sleep. This is horrible medicine."
- Mar...
- Taken for 1 to 6 months
- March 9, 2022
"Horrible side effects. Paranoid, delusional, agitated all the time. Overwhelmed my sense."
- Lin...
- Taken for less than 1 month
- January 15, 2023
"No benefit whatsoever, except emptying my wallet by almost $1,000 for 3 treatments over a 2-week period. The nose spray tasted terrible and made me feel 'spaced out.'"
See also:
Learn more about Depression
- Antidepressants: Options, Advantages, and Precautions
- Mixing Alcohol & Antidepressants: Cause for Concern?
Care guides
Symptoms and treatments
Medicine.com guides (external)
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"An exciting experience that lifts you into a different way of looking at many things. Colors and objects appear more enhanced and even strikingly different than usually experienced, but quite interesting and most surprisingly more in depth."