Esketamine for Depression User Reviews (Page 3)

• Ail...
• Taken for less than 1 month
• July 26, 2019

Esketamine "I am scheduled to begin Spravato next week. I’m very nervous, but am desperate to lift this depression of seven years. It would be so helpful if more people would comment about their experiences with Spravato. I could use the input!"

• Kjo...
• Taken for less than 1 month
• January 2, 2020

Esketamine "An exciting experience that lifts you into a different way of looking at many things. Colors and objects appear more enhanced and even strikingly different than usually experienced, but quite interesting and most surprisingly more in depth."

• Mic...
• Taken for 1 to 6 months
• January 22, 2020

"I started taking Spravato nearly two months ago. Started at the 56 mg loading dose. At four weeks, it had done nothing positive. So the doc upped it to the 84. First off, that first double-dose treatment had me on one hell of a trip. I really felt that I wasn’t coming back! After that treatment, I was hungover, then treatment 2. After that, I was sick as a dog. Severe headaches and terrible nausea. Took me 5 days to recoup, and as of today, still with the headaches and nausea. Called the doc and stopped treatment altogether. I just can’t spend day after day feeling sick, not able to work, etc. This was a last-ditch effort, and now I don’t know just what I am going to do."

• Spu...
• February 4, 2020

"9 treatments. First three weeks, I felt some improvement. Laughing, having motivation. Once a week and feel less depressed for 3 days. Then depressed. Treatment feels amazing! Had IV infusions very intense! I couldn't feel my body. Crazy hallucinations, nothing scary. Enjoyable. Spravato, I feel relaxed like Pink Floyd's Comfortably Numb! No visual disturbances. Listen to Simon and Garfunkel, mellow but upbeat. No rock! I can feel my body, hearing is more sensitive. Music sounds great! Definitely a nasty taste in my throat. Candy helps. I stop feeling the effects after 1 hour, drowsy hour 2. Then normal but rest at home. Headphones and playlist, bring a soft blanket and eye mask. The experience is becoming less pleasurable. Antidepressant effect has been minimal. I wish I could have more IV, it was less $. Pure Ketamine is very helpful. For Spravato, they've taken away one of the molecules. Research it please."

• Lon...
• May 7, 2021

"I've had several Spravato treatments. I must say they have helped me tremendously. All the blah, blah, blah from researchers who say not enough tests have been done, but as I'm sure that while these researchers/MDs treat major depressive disorder, they themselves have not experienced MDD. Spravato has helped me immensely. No SSRI or SNRI has ever really helped. Those drugs, too, have been pushed by big pharma. I've suffered from depression most of my life. This is the first medication where I have experienced dramatic improvement. Don't know what will happen after I've completed my treatments. But I'm grateful for the relief Spravato has given me."

• Red...
• Taken for 1 to 6 months
• March 11, 2023

"It cured my depression. I tried SSRIs and tricyclic antidepressants with no benefits. Now I am feeling good thanks to esketamine. It started to work in one month, and I was 100% fine at the end of the second month. Now I'm still doing my third month, and I have no relapses at all. We are scaling up the drug until it is removed. I'm from Italy, here it is free thanks to the National Health Service."

• Kat...
• Taken for less than 1 month
• June 16, 2022

"I tried 4 doses of high-dose esketamine. It was absolutely useless! Waste of time! Waste of money! The only effect I experienced was that it tasted bitter when it dripped down my throat. I did not have dissociations, hallucinations, nausea, drowsiness, dizziness, or anything else. My vital signs also never changed at all. I simply got angry because I was forced to sit in an empty room, bored silly for 2 hours each time. It did nothing for my depression, suicidal ideation, or panic attacks. Giving me bad-tasting saline would have the same effects as esketamine (and be much cheaper). I think it works purely on a placebo effect! I also haven't responded to numerous antidepressants, CBT, or any other treatments either."

• Art...
• Taken for 1 to 6 months
• July 16, 2024

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• STO...
• Taken for less than 1 month
• March 8, 2019

Esketamine "I am astonished that this made FDA approval. In the emergency room, I was unknowingly given ketamine IV last fall, and as it was being dripped, I screamed for the RN with, 'What is that!!!' When he said, 'Ketamine,' I said, 'Get it out of me!' I was told it was to 'reset my brain,' and I was not at all interested in that."

• Anonymous
• Taken for 6 months to 1 year
• December 27, 2019

Esketamine "Depressed no more. Thanks, Spravato."

• Bru...
• Taken for 1 to 6 months
• January 24, 2020

Esketamine "Really helped. IV is better, but this bridges the gap."

• Sti...
• Taken for 1 to 6 months
• September 24, 2019

Esketamine "Have been on Spravato for over a month now and developing headaches. My anxiety level is through the roof. Still sad but not crying. Going in for assessment tomorrow."

• Dep...
• January 7, 2023

Esketamine "Spravato worked when nothing else did. My doctor wanted to prescribe another SSRI, but I heard about Spravato as adjunctive treatment."

• Jul...
• Taken for less than 1 month
• August 10, 2021

Esketamine "Just had my first treatment. I shouldn’t have been anxious, it was a calm, relaxing experience."

• Guy...
• Taken for less than 1 month
• November 12, 2021

Esketamine "Works great, helps with depression and leaves me feeling wonderful."

• 777...
• October 15, 2019

Esketamine "Anybody have increased suicidal thoughts on Spravato?"

• San...
• Taken for 1 to 6 months
• June 27, 2019

Esketamine "I'm on Spravato, and the 56 mg dose is too much. Sick for 4 days after. Then 1 or 2 OK days. Where are all the other reviews? Doctors know all that I know. They are no help at all."

• Sti...
• Taken for 1 to 6 months
• August 3, 2021

Esketamine "Part of a clinical trial for treatment-resistant depression without any other antidepressants. I have 2 treatments left, and it hasn't worked at all and has made my accompanying anxiety worse!"

• Alb...
• Taken for 1 to 6 months
• March 7, 2022

Esketamine "8 treatments at 28 mg, last two treatments felt terrible during and 3 days after, can't sleep and feel sick. Went up to 54 mg, sickly past 4 days, can't sleep. This is horrible medicine."

• Mar...
• Taken for 1 to 6 months
• March 9, 2022

Esketamine "Horrible side effects. Paranoid, delusional, agitated all the time. Overwhelmed my sense."

• Cap...
• Taken for 6 months to 1 year
• September 13, 2020

"I am now the poster child for this medication, esketamine, it absolutely saved my life! It also helped with substance abuse, which I've struggled with my entire life."

• Lin...
• Taken for less than 1 month
• January 15, 2023

Esketamine "No benefit whatsoever, except emptying my wallet by almost $1,000 for 3 treatments over a 2-week period. The nose spray tasted terrible and made me feel 'spaced out.'"