Synjardy User Reviews & Ratings

Synjardy has an average rating of 6.4 out of 10 from a total of 24 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 26% reported a negative experience.

Condition	Avg. Rating	Reviews	Compare
Diabetes, Type 2	6.4	24 reviews for Diabetes, Type 2	152 medications
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Reviews for Synjardy

Kisha
Taken for 6 months to 1 year
September 19, 2019

For Diabetes, Type 2 "40 year old female. After being diagnosed with Diabetes Type 2 I made some serious changes. Before starting the Metformin I fasted for 5 days which helped reduce my glucose tremendously. After I followed/continued with exercise and watching what I ate I saw some amazing results. After about 1 month of being on Metformin my A1C went from 14 to 9. My Doctor reduced the Metformin dosage and started me on the combination pill Synjardy. After about 2 more months my A1C dropped to 6.5. So far it has worked great and I have maintained below a 7.0 A1C now for approximately a year. I have also loss weight with the medication. I had no negative side effects for the past year until now. For the past few months I’ve continued to get yeast infections. It’s gets treated and it comes back every month after my menstrual cycle. I am making the decision to stop taking the Synjardy and start another medication. Loved it before this uncontrollable side effect."

9 / 10

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31 Report

K2usvi
Taken for 6 months to 1 year
May 4, 2019

For Diabetes, Type 2 "I’ve used Synjardy for 8 months. Thankfully my insurance covers it and with the savers coupon I have zero out of pocket expense which is awesome. So you might be wondering does Synjardy cause weight loss - yes it certainly has helped me lose weight as it suppresses my appetite. I do pee more and am thirsty. I do take vitamin B12 as it’s helped with energy and couple other side effects. Also the Syndjardy has made my A1C go down from a 11.8 to 4.9 within 6 months. Every so often I have tummy issues but have never thrown up from it. All in all it’s done wonders."

8 / 10

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30 Report

Carl
Taken for 6 months to 1 year
October 4, 2016

For Diabetes, Type 2 "Update to my other review. The Dr's office was able to get things straightened out and I was able to get Synjardy for free with the discount card after all. I have been on it for about 9 months now. I have lost around 30lbs, my A1C went from 11.5 at diagnosis to 6.2 at my last Dr's visit and could probably be better if I didn't forget my afternoon dosage all the time. Average fasting BS went from 280's to 110's. I wish I could stay on this forever as it has worked great for me, but I'm sure the discount card program will end at some point. Have noticed increased urination, but nothing too terrible. My dosage is the 5mg-500mg pill twice a day."

10 / 10

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35 Report

Frequently asked questions

Can I drink alcohol while I am taking Synjardy?

Carl
February 29, 2016

For Diabetes, Type 2 "I received a sample of Synjardy and have only been taking it for 4 days. I started off taking 850mg of Metformin twice a day and 5mg of Glipizide twice a day. I had good numbers on this, but the Glipizide was causing too many hypo episodes, so my Dr gave me a sample of Synjardy. The Synjardy has made my numbers more consistently 80-105 and I no longer have any hypo events. I have also lost 4 pounds in 4 days. The only negative I have noticed is having to drink and pee more. It has made me more prone to waking up a little earlier to hit the bathroom, but it hasn't been that bad. They have a savings card, but my insurance will not cover it at all, so I can't use the card and without that it is $431 a month, which I can not afford."

10 / 10

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31 Report

Spanky
November 29, 2018

For Diabetes, Type 2 "Since I have been taking Synjardy for the passed six days I have been throwing up with uncontrollable bowels. I have never experienced this kind of side effect from not even plain ole metformin. I thought I was literally dying from all the throwing up. I will never take this medication again ever."

4 / 10

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22 Report

Are you taking this medicine?

Gare
Taken for 1 to 6 months
April 24, 2023

For Diabetes, Type 2 "Throughout 2022 my A1C's are in the 7's and my blood pressure (BP) was great 107/76 in June and 108/78 in Sept. Day to day blood sugar readings were 5-7 with lots of walking, and light weights nightly, and proper diet and my weight is stable. The doctor decided to add Synjardy and reduce Diamicron by 50% in late October. The next A1C in Dec. was 8.3 with a BP of 135/84. Day-to-day blood sugar readings (B/S) are way high 10-13. Requested taking diamicron. The doctor worried about low blood sugar and did not comply. My next A1C was 8.3 in March but my BP was 154/84. The doctor suggested I check my B/P weekly at a local pharmacy. One week later 196/106 B/P..Ten more checks all around 180/95. Totally out of whack as were day-to-day B/S. Still, walk miles every week and have no diet changes. I see the doctor again in 3 days. The only difference in my life is the addition of Synjardy and the reduction of Diamicron. I've stopped weights. Day to Day B/S is impossible to get on track. Something is out of whack! I am 66 years old and was great till the last six months."

2 / 10

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6 Report

Peonni
Taken for less than 1 month
February 8, 2021

For Diabetes, Type 2 "It's unreal how quickly and drastically my fasting blood glucose dropped. Within 1-2 days it dropped approximately 100 points and I was thrilled! Now I should be able to stay off insulin for a while. (Whew!) I was already on 2000 mg of Metformin ER, and Glimepiride. I tried using Farxiga and I don't think it made a significant difference. But man! This Synjardy! Try it if you can. Only side effect for me was it may have made me thirstier than usual. No big deal."

9 / 10

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13 Report

Ruben...
Taken for less than 1 month
December 1, 2016

For Diabetes, Type 2 "Ive been on it for a week now, since switching from metformin I've noticed no more aches and pains and have been able to workout since the 2nd day of changed! love this Synjardy so far using samples so have no idea on price and insurance but ill deal w that when it comes to it."

10 / 10

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22 Report

Big...
Taken for 1 to 6 months
January 14, 2020

For Diabetes, Type 2 "Dr. put me on Synjardy and after 3 months, with no change in diet my A1c went from 5.7 to 8.9!! For the money you would think it would be a miracle drug. I think I will stick with the cheaper metforman that maintained a 5.7 A1C"

1 / 10

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14 Report

Lbs
Taken for 1 to 6 months
June 15, 2018

For Diabetes, Type 2 "I love this drug! I have lost 17 pounds in 11 weeks and I feel great. No low blood sugar episodes anymore and no stomach issues like when just taking Metformin. I do have to pee a lot more due to increased thirst but it’s manageable. I am using samples because my insurance won’t cover any diabetes care ( short term plan with denied pre-existing condition coverage) so I’m worried what I will do when my dr can no longer give me samples. Starting AC1 before Synjardy on Met/glyburide was 8.8. Now I’m below 6 and it’s only been 3 months. Waking numbers used to be 160-190, now they are average 118-120. No side effects for me. Weight loss for me comes from feeling like I have eaten a ton of food when I really haven’t. I push my plate away earlier too. I m very active though and do intense cardio/training classes so maybe the combination of feeling better and medicine has kicked my metabolism into full speed. Lol."

10 / 10

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17 Report

Maze...
Taken for 6 months to 1 year
July 25, 2019

For Diabetes, Type 2 "This drug is magical! Lowered my A1C from 11.8 to 5.4 in 3 months. For 6 months I was on 1000 mg/12.5 mg twice daily. My doctor has now decreased it to once daily. I dropped about 22 Kg in 6 months. I suffered from tolerable side effects such as upset stomach and hypotension. I don’t fee thirsty and urination frequency is normal. Made me hate red meat :)"

10 / 10

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14 Report

Carla
Taken for 1 to 6 months
May 8, 2019

For Diabetes, Type 2 "I've been on Synjardy for about 3 months. Sugar levels are more consistent. No more sugar crashes and I've lost 13 lbs. No other side effects. It's working great for me! Dr gave me a coupon so I get it free for 12 months."

10 / 10

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13 Report

TAano
Taken for 1 to 6 months
August 18, 2019

For Diabetes, Type 2 "After one month this medicine Synjardy brought my a1c down from 8.3 to 7.1. My glucose from 288 to 116. The only problem is that it is giving me vaginal yeast infection and it is severe. It goes away a week with meds and comes right back so I will have to stop. Also a little nausea. I was getting good results."

7 / 10

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12 Report

SRano
Taken for 1 to 6 months
October 17, 2020

For Diabetes, Type 2 "My Doc prescribed Synjardy with 12.5mg/500 mg Metformin twice a day. My daily numbers dropped from 145 to 120 in last 2 months . Also my weight reduced by 10 lbs (7% of my total weight). But my blood pressure dropped to 100/60. Earlier it was 117/75. Starting to feel dizzy. Planning to talk to my Doc on low BP."

6 / 10

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9 Report

belle...
Taken for less than 1 month
August 24, 2022

For Diabetes, Type 2 "I am 47 years old on an insulin pump and have had pancreatitis 4 times in my life due to high triglycerides. I am currently taking Ozempic at the lowest dose because I am afraid of pancreatitis revisiting (worst pain ever). Last week my Dr put me on the Synjardy and my sugars this last week have been under 150 even after eating. I will say that I do watch my carb intake keeping it under 30 per meal and I lost 4.2 pounds this week. I don’t know if these results are normal but currently I am a believer. I cannot wait to see down the road if I have continued success. I have had frequent headaches but I am hoping those pass. Hope this helps someone."

8 / 10

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5 Report

luv2sew
Taken for 2 to 5 years
April 27, 2019

For Diabetes, Type 2 "I have been using the Synjardy for the past 3 years and have found it is better than straight Metformin. I could not leave the house when I was taking 2 - 1,000Mg tablets of the Metformin. I am taking the 12.5/1,000Mg tablet 2 times a day and I am having no problems with it. It has lowered my morning glucose readings closer to 100, and my after meal readings under 180 which is what I needed. Seems like the mix of the two drugs works better than Metformin alone."

10 / 10

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11 Report

Homer
Taken for 1 to 6 months
April 19, 2020

For Diabetes, Type 2 "It really help me lower my sugar but it gave me difficulty breathing and because of that I also couldn't sleep well. I wish Synjardi didnt have such side effect on me cause it really works. But with strict diet and exercise i have been able to keep my sugar in normal range."

6 / 10

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9 Report

Twink
Taken for 2 to 5 years
July 20, 2021

For Diabetes, Type 2 "This medication has really controlled my blood sugar dramatically compared to Metformin alone. My HBA1C levels are at 6.8 currently. I have had a few yeast infection over the couple of years that I've been on Synjardy. But Miconozole ovules seem to take care of it. Much happier being on Synjardy compared to before."

9 / 10

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4 Report

EDM
Taken for 2 to 5 years
September 5, 2022

For Diabetes, Type 2 "THIS DRUG IS TRASH used this drug for over 2 years this company Eli Lilly should be investigated they put something in the that drug to makes you crave for sugar. My AC1 went up to 11, it was at 9 when I started. Then started Xigduo for the past 3 months no craving for sugar everything went down"

1 / 10

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2 Report

Ron
Taken for less than 1 month
September 12, 2021

For Diabetes, Type 2 "Been taking this medicine for five days, can’t sleep, have heart palpitations, nauseous dizzy and I respect other people who are successful. It just doesn’t work for me at all I’m going back to metaformin, will exercise better. I think this stuff is awful And it was $500"

1 / 10

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2 Report

Kev
Taken for 2 to 5 years
August 22, 2021

For Diabetes, Type 2 "I take it along with Metformin ER and Ozempic. My A1c is in the low 6's but I'm not 100% sure which one helps the most though Ozempic led to a 30lb weight loss which I'm sure was a big factor. Unfortunately, the Synjardy savings card went from paying $70 to only $40 this past month so my out of pocket with insurance went from $30 to $60 per month. I may stop taking it soon to see it's real impact since their "pays up to $175 per month" card only covers $40!"

5 / 10

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1 Report

Imad
November 18, 2018

For Diabetes, Type 2 "There are new research stating that this drug might cause pancreatitis Or even cancer of the pancreas ! Can any one comments on this post please !"

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21 Report

KTano
Taken for 1 to 6 months
January 30, 2019

For Diabetes, Type 2 "My new physician switched me from Farxiga to Synjardy 3 months ago. A1C has gone from 6.5 to 8.7 which is the same before I began taking Farxiga almost 3 years ago."

1 / 10

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11 Report

Bill
Taken for 1 to 6 months
March 8, 2020

For Diabetes, Type 2 "Severe thrush,stomach problems, headaches, high cholesterol, worse now than l was taking metformin 500mg."

1 / 10

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9 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.