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Doxepin User Reviews & Ratings (Page 5)

Brand names: Adapin Silenor

Doxepin has an average rating of 6.1 out of 10 from a total of 422 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Doxepin

  • Proper...
  • Taken for 1 to 6 months
  • July 28, 2017

For Insomnia "Doxepin does not help me fall asleep. It does help me stay asleep. I suffer from anxiety and depression and that's why I can't sleep. To those people who have experienced extreme tiredness the next day this also happens to me even though I take it as the manufacturer suggest for Sleep maintenance which is to take on a completely empty stomach 3 hours after a meal. Otherwise the onset is delayed even further. By several hours leading to next day sedation even more. Even when taking the proper way it has a 15-hour half-life which can still leave you tired and groggy the next day which I also experience even taking it correctly."

4 / 10
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  • Sleep...
  • March 18, 2016

For Insomnia "Doxepin for sleep?. My new psychiatrist has prescribed this drug . New because my previous doctor passed away. That man was a God send for years and years to me. I don't sleep but 4 or 5 hours a night. Broken up 2 hours at a time. But doxepin? Seriously? Is this some kind of cruel joke? Can anyone hear me? I CAN NOT SLEEP!!! HERE I AM RIGHT NOW 2:12AM. Perhaps next he will add melatonin, a warm glass of milk and journaling before bed....lol. Maybe Yoga, chanting and acupuncture. I give up. It has been 47 days now on this drug. My last night of this ridiculousness."

1 / 10
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  • May
  • Taken for 1 to 6 months
  • December 9, 2020

For Urticaria "Waking up every day with chronic hives all over my body (no known cause) for months that wont go away with benedryl, singular, allegra, and even xolair, my new allergist suggested doxepin. At this point, I was willing to try anything that could make them stop. When I tell you I haven't had a hive on my body since starting doxepin, its no joke. Doxepin has been a life saver and has helped tremendously with my chronic hives."

9 / 10
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23 Report

Frequently asked questions

  • RGano
  • October 11, 2020

Silenor (doxepin) for Insomnia "I was on Ambien for years. It worked great, but at the time I wanted to get off controlled medications. With Silenor I actually had no problem falling asleep. Couldn't believe it worked. I've tried about every OTC sleep aid and one non-controlled sleep aid (Belsomra). OTC's did nothing and the Belsomra I threw in the trash after the first night taking it. I only recommend it if you like feeling drugged and anxious all night. Also gave me extreme light sensitivity where I couldn't look at my nightlight. So in all, Silenor was a great to help me sleep."

9 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • November 25, 2015

For Insomnia "Had a brain injury, sleep 2 to 3 hours a night. Take Doxepin 10 mg I have found to take the capsule a part dump out about 5 mg of medicine. I can sleep 6 to 7 hours and wake up feeling great. No hangover. Even if I wake up during the night I can go back to sleep. This drug is wonderful if used correctly"

10 / 10
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Are you taking this medicine?

  • Finally...
  • Taken for less than 1 month
  • June 21, 2017

For Insomnia "After the doctor tried other pills on me for depression, anxiety, PTSD and insomnia with horrible nightmares he decided to try 100mg of Doxepin in the evenings saying it was an older pill not used as much anymore. My body is resistant to medications and requires high doses of meds in order to notice any affects. Its hard for them to knock me out for surgery and keep me knocked out. But so (it's only been about a week) far the Doxepin has been working great at making me sleep. It takes several hours to knock me out but when it does I'm out without waking up every 10 minutes in misery with nightmares and physical pain. I tend to be groggy in the mornings though. I hope my body doesn't grow resistant to it."

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  • Anonymous
  • October 28, 2010

Silenor (doxepin) for Insomnia "I had been using Ambien for years but gradually developed a tolerance to this medication. I was also frustrated with the frequency of waking during the night. My GP prescripted 6.0 Silenor tablets about two weeks ago and thus far, I am very pleased with the effect on sleep maintenance."

10 / 10
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  • Matvei
  • Taken for 1 to 6 months
  • February 22, 2020

For Insomnia "I have sleep maintenance insomnia/early awakenings (no trouble falling asleep in the first place, but a world of hurt trying to stay asleep after 4 or 5 hours). Doxepin worked like a dream for about three months - good (7 hours) sleep, no side effects - then zilch, nothing, back to the bad old days, even if I took ten times the dose. If you have mild/moderate insomnia, this should work for a while, but don't bank on it long term. Cheap too as a generic."

5 / 10
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  • GDano
  • May 28, 2018

Silenor (doxepin) for Insomnia "I was prescribed Silenor for insomnia which I battled with for 3 years. I was taking a high dose of Melatonin to sleep but that stopped working when I was going through a stressful period. Took 3 mg of Silenor the first night. Although I slept 5-6 hours , I felt horrible the next day. I felt like crying all day. I increased the dose to 4.5 mg and was able to get 7 hours of sleep but the negative mood became more prominent during the day. I was depressed and miserable. I stuck with it for 2 weeks but my mood was getting worse. I couldn't keep on taking it. I don't know if this is only initial side effects that will go away after a month or so but I personally could not handle the depressive symptoms (major) it gave me so I decided to stop it after 2 weeks only. I felt better immediately even though I am still struggling with sleep... I have to see my doctor and try Trazodone."

2 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 16, 2019

For Anxiety "I started on doxepin 75 mg 15 days ago. I have notice a decrease in my anxiety, excitableness, and obsessive thinking and thoughts. I use to have a problem sleeping. Not anymore!! I am asleep in about 20 min and I stay asleep. I use to be such a light sleeper, and never got more than 5 hours of sleep. I use to take Gabapentin for nerve pain. However, I haven’t needed it since taking Doxepin. I noticed it also takes my appetite away. Now for the horrible side effects.....I have to force myself up. It takes me a few hours to fully be awake. I was in a horrible brain fog for the first 10 days. The first four days I felt like I had the flu. Now I am still dealing with the tiredness. I don’t want to stop it. However, I will if the tiredness doesn’t subside. I am glad I have had no headaches on the medicine, as other meds have given me."

8 / 10
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  • Oldst...
  • January 24, 2016

For Urticaria "Doxepin is a godsend for hives. But I have found several drawbacks for it. First, drowsiness. You need to take it before you go to bed. Probably even just slightly after dinner. Even then you will find yourself sluggish in the morning. Second, since it is an anti depressant, I tend to develop an I don't care attitude with it. My personality is to be that way normally and this exacerbates it. It isn't necessarily bad just something to be aware of. Finally, I find it inhibits weight loss. It doesn't necessarily cause weight gain, but, it causes me to sweat less when exercising. When I get off it I tend to lose weight pretty rapidly. But all the side effects are worth it to be hive free."

10 / 10
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42 Report
  • MS407
  • October 29, 2016

Silenor (doxepin) for Insomnia "Difficulty sleeping through nite I did sleep first night but then most of next day on silenor. 2nd night tossed and turned but slept for about 4 hours. Felt drugged the next day. Took 3rd night slept off and on. Felt horrible next day, tired, weak feeling, headache. Also leaves mouth extremely dry. Not going to take silenor any more."

9 / 10
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  • Cano
  • Taken for 1 to 6 months
  • June 16, 2019

For Insomnia "I’m a 68 yr old female who falls asleep easily but has difficulty staying asleep. Doctor prescribed 10 mg Doxepin which helped with staying asleep all too well. I had trouble waking up at usual time. Insurance won’t pay for lower dosage, so I cut 10 mg capsules, which always results in losing some medicine, but the slightly less than 5 mg works greats do reduces cost too boot. No ill effects at this dosage."

8 / 10
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  • PHick
  • April 21, 2016

Silenor (doxepin) for Insomnia "Been using it for about 5 months and it has been a miracle worker until recently. A few weeks ago started having random sleepless nights. This week has been terrible waking up after 3-4 hours and feeling wide awake. Not sure if my body is getting used to it but I thought I'd check the reviews to see if anyone else has had the same problem. I hope this is a fluke because Silenor really had changed my life and even though it was expensive it was worth being able to function the next day."

8 / 10
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  • Needs...
  • Taken for less than 1 month
  • October 1, 2018

Silenor (doxepin) for Insomnia "I tried both the 3mg and the 6 mg to try to sleep and they did nothing for me. I didn’t feel anything and I still had a hard time falling and staying asleep. I didn’t have any side effects but also no sleep. My doctor gave me samples of the medicine to try so I thought I’d give it a hopeful shot but it just didn’t do anything for me."

2 / 10
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31 Report
  • Paited
  • Taken for less than 1 month
  • January 17, 2020

For Insomnia "Started dose of doxepin was 10 mg for insomnia. Slept some but definitely not enough. Moved dose up to 20 mg and I’ve done well thus far with few awakenings. I'm off Xanax after 15 years. Finding anything to help me sleep has been a huge challenge. Try this. Get doxepin generic not the the name brand or you will pay $$$$$"

8 / 10
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  • ValC
  • October 3, 2016

For Insomnia "I've had sleep issues for years and after having multiple sleep studies done as well as nasal surgery to fix deviated septum, I tried a dental sleep appliance and a c-pap machine and nothing worked. I was finally given Doxepin - OMG LIFESAVER...6 drops per night and I am out like a light wake up around 5 hours later but refreshed and not tired. However, if I go off routine, as in different time-zones, late nights, it does take a while to get back on track...I'd be in a mental health institution if I hadn't found this as I was at the end of the rope and couldn't cope anymore being constantly exhausted."

10 / 10
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  • Thatc...
  • Taken for 1 to 6 months
  • October 5, 2018

For Insomnia "I was put on many different sleep medications before Doxepin and nothing worked for how bad my insomnia is. My doctor had to put me on 30mg of it just to get it to work at all. But once we got the dosage right it works perfectly. Puts me to sleep in 10 to 15 minutes. Other people freak out with my high dosage but, if it works it works. The only downside for me was when I take it I have to sleep for 8 hours or more my body literally will not wake up otherwise. Whenever I did manage to wake myself up before 8 hours I always ended up falling asleep while I was doing something."

8 / 10
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30 Report
  • Buffs
  • June 23, 2014

For Anxiety "My Dr. Prescribed me Doxepin 10mg. For depression, anxiety, and insomnia. So far so good, calms me down wonderfully when my three kids or my husband cause me to have an anxiety attack, and is working well with my depression. Only things it isn't doing to much for my insomnia I still go to bed at about 9pm and fall asleep around 2:30-3:00am. I have also taken Lexapro which worsened my depression, Zoloft just made me feel like a zombie or like I was wired out of my mind, and Prozac which worked great on me but since I have insomnia my Dr. gave me Doxepin."

6 / 10
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  • Mark4...
  • Taken for 1 to 6 months
  • November 22, 2019

For Insomnia "Amazing how varied responses are to this drug doxepin! I take a 50mg capsule before bed and sleep well for 7-8 hours . Have vivid dreams but not nightmares and wake refreshed on a good day but not always. I find it better than elavil."

10 / 10
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  • Craig
  • Taken for less than 1 month
  • February 4, 2020

For Insomnia "Took it for insomnia, and I did sleep, woke up several times as usual but I did sleep better. Trouble came the next morning. I should have taken it on a weekend and not on a work day, almost impossible to get up and moving the next morning, hangover all day. Will not be using again"

1 / 10
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  • Anonymous
  • May 2, 2010

For Anxiety "I have been taking Doxepin for 26 years to treat depression and acute anxiety. It has worked well and enabled me to feel normal and lead a normal life. Recently though it has stopped working as well and I am having panic attacks and anxiety again. I think I have become immune to to it because of taking it for so long. Would like to switch to a newer drug but my doctor is not keen to swap me."

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  • berry...
  • Taken for 1 to 2 years
  • June 29, 2016

For Insomnia "I've been taking 100mg @ night for insomnia/anxiety for approximately 1 1/2 years! I love it! I take it about 30-45 minutes before bed and BAM I'm out! The only side effects I've noticed is talking in my sleep (nothing major though)!! I would highly recommend this medication for insomnia."

10 / 10
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  • Dizzy...
  • Taken for less than 1 month
  • March 10, 2017

Silenor (doxepin) for Insomnia "Silenor works very well keeping me asleep longer than usual. I normally wake up 3-4 times a night without it. But I have extreme dizziness and headaches the next day. I think I'll go back on my Lunesta because I have trouble functioning the day after Silenor. It is a great medicine but I'm not sure if it's for me."

8 / 10
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  • asiss...
  • Taken for 1 to 2 years
  • September 17, 2016

Silenor (doxepin) for Insomnia "I have trouble sleeping from 3 - 6 am. I wake up and cannot go back to sleep creating the daytime symptoms of insomnia (see: http://www.mayoclinic.org/diseases-conditions/insomnia/basics/definition/CON-20024293 ). I rarely have trouble falling asleep. I have been taking LIQUID doxepin for 18+ months (along with a 5 mg time release melatonin) - 30 min before bedtime. The LIQUID has to be especially prescribed by your Dr and approved by your drug company. A 120 ml bottle is $79 - with medicare & drug co approval, my out of pocket (last bought in 6/2016) was $7! Much cheaper than Silenor. I am prescribed 0.6ml/night, but sometimes I take 0.5ml or less, & never over 0.7ml (rarely). Doxepin & melatonin work well to help me sleep from 10p-6a!"

9 / 10
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36 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.