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User Reviews for Pristiq (Page 9)

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Pristiq.

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22%(130)
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15%(91)
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9%(50)
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6%(33)
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5%(29)
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Pristiq Rating Summary

7.3/10 Average Rating

607 Ratings with 585 User Reviews

What next?Compare all 217 medications used in the treatment of Depression.

Reviews for Pristiq to treat Depression

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"After being in denial, I completely broke down with anxiety and depression. Went to my doctor and prescribed me Pristiq. After a week I took a big turnaround for the best, so happy! Stick with it, give it a chance to work. Side effects were nausea for the first few days stomach upset, but don't give up! I have been on Celexa in the past but takes to long to kick in..plus 40lbs weight gain. Pristiq cuts the appetite ,and you not hungry, at least if you needs a few lbs off this is the medicine to be on!"

   
10

Mary Dom May 16, 2013

100 users found this comment helpful.
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"I've been suffering from major depression & anxiety for the past few years until I finally decided I've had enough! Initially I was prescribed Cipralex which helped with my anxiety but I gained way too much weight & couldn't stop eating so after approx 6 months I went off it which wasn't hard at all, no withdrawal symptoms. I was then put on Wellbutrin 150mg then after approx 1 month up to 300mg. I felt great positive energy lost a lot of the weight I gained. After approx 1 year I felt that this med was totally ineffective & I wasn't feeling anything. My doc then prescribed Cymbalta which appeared to work well for approx 1 month then after the next 2 months I didn't feel anything. Now I'm on Pristiq for just over 5 weeks, I feel good."

   
9.0

So far So good May 16, 2013

43 users found this comment helpful.
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"I have been on Pristiq for 9 months now. I had the night sweats in the beginning and they went away after about 3 weeks. I thought the only other side effect I've experienced was when I would forget to take a pill. The next day I would be dizzy and would snap at people. The following day would be back to normal. I also have a bite guard to help with the jaw at night. I don't use it that often. I noticed in the past week my depression returning slightly. I was confused because Pristiq has worked wonders for me. Realized I have a sensitivity to caffeine. I love Dr. Pepper and quit drinking it when I started Pristiq. Started drinking DP again and had stomach problems and depression. So no more caffeine! I take 50mg."

   
10

JTSHappy May 1, 2013

63 users found this comment helpful.
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"I have dealt with depression stemming from an incident in my profession. I was initially on Zoloft for about 1-2 years. It worked OK but after a while not so much and all I got from it was that zombified "what's the point of life anyway" feeling. I switched to Pristiq and it was much better. It cuts the depression but doesn't give you that blahed out zombie feeling that the SSRIs can do. I don't have much of the side-effects luckily. I have noticed it takes longer to ejaculate (but I think my wife sort of likes that part of it- sorry for too much info). Anyway Pristiq is a great medicine. I noticed some people here had bad experiences with it. I think that's to be expected with all antidepressants. Keep trying and find the right one."

   
9.0

depresseddad April 30, 2013

67 users found this comment helpful.
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"I have suffered depression off and on for over 20 years. I take Cymbalta for chronic pain and still have fallen in a deep depression. My doctor added Pristiq and after day 1 I'm feeling much better!"

   
10

Gigiagain April 29, 2013

35 users found this comment helpful.
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"Have been on Pristiq for 5 years. Started at 50 mg and after a few years kind of felt like it was wearing off. Upped to 100mg. For depression it worked great for 5 years but now wearing off again. I have side effects of clenching my jaw so terribly I needed a mouth guard at night, it has increased to where I have broken a tooth! Also, memory issues and tinnitus that can drive you nuts (no pun intended!). But, gotta say, it worked for me. Now slowly weaning off and trying Wellbutrin."

Margaretmarie (taken for 5 to 10 years) April 23, 2013

35 users found this comment helpful.
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"Was on Effexor for years. Learned that Pristiq has less side efect on sexual dysfunction. After being on Pristiq, I felt it was effective, gentle and my sexual issues improved."

   
9.0

Highridge (taken for 2 to 5 years) April 10, 2013

55 users found this comment helpful.
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"Depression has got worse causing me to miss work. Have been on 20 different antidepressants over 7 years. Pristiq didn't help at all for me, headaches, foggy and nausea. Also shaky at times."

   
1.0

doneit April 4, 2013

35 users found this comment helpful.
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"I have tried dozens of antidepressants in the past. None of them really worked for me. In 2009 I saw a new doctor who prescribed Pristiq. The beginning side effects weren't great, I had increased anxiety, night sweats, and trouble sleeping. The side effects only lasted the first week. I recently changed insurance and my copay was quite high, so my doctor decided to try something cheaper, which was Wellbutrin. I was on that for 8 weeks and I never felt worse in my life! I cried all the time, constantly feeling the fight or flight response. The anxiety was unbearable. Recently had my doctor put me back on the Pristiq and all is well. Worth the copay!"

   
10

justsayin78 (taken for 2 to 5 years) April 3, 2013

56 users found this comment helpful.
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"20 yo female. I had my first dose at 50mg this morning. After battling depression and anxiety for about 3 years, I made the choice to start meds when it became too much to bear. What I can tell you about my day is that it's been an experience! Feeling foggy, dizzy, slightly nauseous. The strangest side effects were the extreme hour long high, fidgeting, and a huge compulsion to clench my jaw/grind my teeth. Regardless of the side effects (remembering it is only day one) I have felt not only happiness, but joy, comfort, and decreased anxiety. Before today I can't remember the last time I had a good laugh. "

   
9.0

Chantellouise March 24, 2013

84 users found this comment helpful.
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"Been on this for about a week. So far the pros are: I am much calmer. I have a very stressful job that used to have me yelling and wanting to pull my hair out. Now I'm calmly discussing issues with a reasonable mind. Also I noticed I have more energy and much more positive outlook on life. I've even lost a few pounds because my appetite is somewhat suppressed. The cons are: very vivid dreams. Just about every night I have a very lucid and lengthy dream about something in my life. Another con is the first few days I felt a little "out of it" as others have said, but that stopped after about 3-4 days. The last con is that it's expensive. I have two insurances and still had a copayment. But I like it so much, it's worth the price."

   
9.0

Monkenbak (taken for less than 1 month) March 18, 2013

78 users found this comment helpful.
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"This medication is amazing! After 3 days of being extremely sick, I started to feel amazing, I am now 1 month into it and am so happy all the time and have no depressive thoughts at all. It kind of blocks out any sad thoughts. Works perfectly for me."

   
10

hayley665 March 10, 2013

101 users found this comment helpful.
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"I was on Prozac and it wasn't working anymore. I tried Pristiq and for the first couple of weeks I didn't feel "right". Then, I started feeling much better. I also take a prescribed supplement called Deplin because my body doesn't absorb folic acid- a source of my depression. I don't know if it's the Deplin, the Pristiq or both, but I don't get depressed anymore. I do get kind of "mean" when I drink coffee with it. My sex drive is loooooow and achieving orgasm is difficult. I also suffer from dry mouth at night. But, I'm here to rate the medication on how well it helped my depression and it helped so very much. It's expensive, even with insurance."

   
9.0

SarahBerry (taken for 1 to 6 months) March 1, 2013

50 users found this comment helpful.
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"I love this. I used to have major mood swings. I feel so much happier. I'm a recovering meth addict. I started this medicine in rehab. 6 months at 50mg and life couldn't be better. All of the anxiety and nerves, tics and repetitive thoughts I no longer have. Pristiq and AA saved my life."

   
9.0

Melissa114 February 25, 2013

103 users found this comment helpful.
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"Best medication EVER! After 2 years of feeling angry and upset and constantly fighting with my husband (over stupid things) and having suicidal and self harm thoughts purely from severe depression, I am now feeling 100% absolutely fantastic ALL the time thanks to Pristiq! Before I could barely get out of bed now I have heaps of energy to last all day and am constantly on the go. I LOVE how this medication makes me feel. I'd highly recommend trying this antidepressant."

   
10

WC. (taken for 1 to 6 months) February 25, 2013

118 users found this comment helpful.
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"I have suffered from anxiety and mood swings most of my life. But since my divorce and living alone the depression was becoming debilitating..... Feeling paralyzed by fear and barely functioning by taking Xanax. Friends and family were very concerned that I was going to drop off the edge. I am highly sensitive to medication. And having tried over 1/2 dozen antidepressants with side effects, I thought I was doomed to a life of torment. A friend was taking it and liked it, So, I tried it. I did have side effects in the beginning. Nausea, loss appetite, racing heart but most are now gone. I still clench some and my jaw gets sore. But I am so much better! 4 months was a big turning point for me. So don't lose hope!"

   
9.0

sisaree (taken for 1 to 6 months) February 12, 2013

80 users found this comment helpful.
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"My doctor prescribed Pristiq to help me deal with overwhelming grief after death of my son. I never took any antidepressants before, so I have nothing to compare it with. It worked very well for me, after taking it for just 3 days,without major side effects. I don't cry everyday like I used to, but also feel somewhat emotionally numb. I am calmer, happier and able to go on with my life."

   
9.0

grievingmom (taken for 1 to 6 months) February 10, 2013

70 users found this comment helpful.
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"I've been on Pristiq 50mg. I'm only 18 it felt like it made me worse at times, it didn't do too much. I'm now off it and waiting to start a new antidepressant."

   
1.0

eesee February 10, 2013

23 users found this comment helpful.
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"20, female. I've been taking 100mg for 18 months I feel a lot better than what I did in regards to my depression but I feel nauseous 70% of the time and if I accidentally forget a pill I feel absolutely awful. Bizarre dreams, incredibly tired, diarrhea and paresthesia. I'm afraid to stop taking it for good because of what it does to me, something I'll be discussing with my doctor."

   
4.0

Let23 February 6, 2013

33 users found this comment helpful.
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"Really work for me, no side effect"

   
10

Anonymous (taken for less than 1 month) February 3, 2013

23 users found this comment helpful.
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"I have been off and on meds for many years, I thought 120mg of Cymbalta a day was working, then I went to see another DR about racing thoughts and ways that I could end my life. So the DR and I went over my protocol with a fine tooth comb and he moved some things around. He put me on Pristiq (oh great another one to try) but this was different. I started with 50 mg and then to 100 mg within 48 hours. He also added Valium 10 mg 4 times a day and I feel great. Everything is changing for the good and I hope that you talk with your DR about this. The only thing bad I can say about this medicine is that I wished that I had found it sooner. "

   
10

BrentC (taken for less than 1 month) February 3, 2013

79 users found this comment helpful.
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"I'm 22, and my doctor changed me from Effexor to Pristiq for my OCD and OCPD. Most noticeable side effect is definitely the appetite loss, but I don't seem to be losing much weight thankfully. If I'm busy and don't think about it, I go all day without food- it's nuts. Also I am having a lot of headaches, but I cannot be sure its the medicine. I sweat A LOT on this, and if I take it too late in the day I cannot sleep. My OCD seems to be in check- much better than Effexor. I've been taking 50 mg for 5 months now."

   
8.0

kayls02 (taken for 1 to 6 months) January 29, 2013

41 users found this comment helpful.
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"I switched from Effexor when Pristiq became available at the suggestion of my psychiatrist. Effexor was an improvement on my previous medication but I still suffered some anxiety and I experienced increased sweating. Pristiq seems to have reduced my anxiety levels and the sweating may have eased slightly and also, my mood improved. More recently I have also been prescribed dextroamphetamine (for ADHD), which improved my mood further, enabling me to halve my daily dose of Pristiq to 100 mg. I did this with the aim of reducing my sweating coming into summer (I am a resident of Sydney, Australia where the summers are typically hot and humid)."

   
8.0

Needlemeyer January 5, 2013

27 users found this comment helpful.
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"Started with 50 mg Pristiq but still suffered anxiety. Now taking 100 mg for the past 3 months. Anxiety has improved. "

   
9.0

ASak (taken for 1 to 6 months) December 30, 2012

34 users found this comment helpful.
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"I was suffering severe depression from a total inability to cope with a traumatic situation I had been through. Pristiq worked wonders the first couple of weeks. I was enjoying life again. Silly me, I didn't pay any attention to the side effect information. It all started with significant weight loss 25 lbs. I originally weighed 120lbs, then I stopped sleeping. I became panicked, one pupil became very dilated. Terrible situation."

   
1.0

unhappy user December 27, 2012

39 users found this comment helpful.
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