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Clozapine User Reviews & Ratings (Page 3)

Brand names: Clozaril, Clopine, Versacloz, Clozapine Synthon Denzapine

Clozapine has an average rating of 8.0 out of 10 from a total of 69 reviews on Drugs.com. 72% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Clozapine

  • Wowdrug
  • Taken for 1 to 6 months
  • December 7, 2021

For Schizophrenia "I have tried many antipsychotics with little results for my symptoms improving. Loxapine was one that worked for me and I was on it for about a year. I figured I'd try clozapine because I heard it's the best one. After spending 3 months in the psyche ward to try clozapine, I really must say, it worked almost like magic. Within a few weeks I was feeling much better. By the end of the 3 months in hospital my voices were very quiet and in the background. It improved my sleep and even helped my delusions and anxiety/paranoia a bit. I am very happy to say, my schizophrenia is much better and easier to deal with."

9 / 10
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10 Report
  • Livin...
  • Taken for 2 to 5 years
  • June 22, 2022

For Schizophrenia "I have been on so many medications and misdiagnosed since I was 17 am now 50... finally after much hesitation was put on Clozaril. A Miracle Drug I sleep, voices seem in the background and am able to have my windows and door open in my home! It worked almost instantly I wish I knew about this sooner I think my life would have turned out different! I now am enjoying life. Only side effect is nighttime incontinence. Such a little price for having a life! On 50mg during the day and 300mg at night."

10 / 10
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8 Report
  • A Fri...
  • Taken for less than 1 month
  • March 28, 2021

For Schizophrenia "Avoid taking it with alcohol, causes extreme drowsiness, trouble breathing, spinning head, unresponsiveness to the point the person could not call an ambulance himself if he was alone. This drug has serious side effects."

1 / 10
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12 Report
  • Mano
  • Taken for 2 to 5 years
  • April 30, 2019

"This was used as a last resort for me for my Bipolar disorder after being in the hospital as most medications I had tried previously were not helping me. I would definitely say that clozapine saved my life and helped me out of some very dark times, but it also comes at a cost. Before I started it 3 years back, I weighed 160lb and now I’m 250lb pounds. I’m always tired and could easily sleep 12 hours. The constant blood work is also very annoying. If needed this drug can be beneficial but be warned that it has many side effects"

6 / 10
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16 Report
  • CJK
  • July 7, 2015

For Schizophrenia "I've been on it for 4 weeks, and I don't see a big difference. I used to socialize at coffee shops, but now I feel paranoid, and I want to stay home. There are so many other things that can be wrong since I take several other meds like Depakote ER and Zoloft. I'm going to see my doctor this week, and hopefully find something to help with mood stabilization."

7 / 10
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22 Report

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  • Itisn...
  • Taken for less than 1 month
  • November 25, 2021

For Schizophrenia "This is one of the worst drugs I have ever tried. I could barely stand a half of the 25 mg pill but my doctor insisted on taking it and started to increase the dosage to 100 mg. I started forgetting things. I couldn't sleep well."

1 / 10
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8 Report
  • alias
  • Taken for 1 to 6 months
  • June 17, 2019

"I had treatment resistant depression and I felt pretty good on clozapine except within a month or two, I gained 30-40 POUNDS. This was probably also exacerbated by my usage of seroquel (for sleeping and behavioral issues) but it was a very noticeable difference. I had to get a blood test every single week for my white blood cell count, I think. My psychiatrist never told me that there was such a high risk of weight gain (because it’s not just me, there are numerous case studies about how it’s a high risk weight gain medication) because she basically made it seem that clozapine was my only option at the time and knew I wouldn’t take it if I knew I would become overweight. well."

3 / 10
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13 Report
  • Matt
  • Taken for 6 months to 1 year
  • April 19, 2021

For Schizophrenia "Was put on different medications; for a while Zyprexa and Risperidone. Neither did much. The Zyprexa helped me sleep. Got put on Clozapine as a last resort and for the most part it helps with hallucinations. Only negative side effect experienced is moderate drowsiness. Might have my doctor lower the dosage next appointment."

9 / 10
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8 Report
  • shahn...
  • Taken for 2 to 5 years
  • January 22, 2018

For Schizophrenia "I am using Clozapine 1 mg from last three years coz I am suffering from auditory hallucination from 2010 till now. I am under treatment and my doctor is saying I will have to take medicines whole life and there is no permanent solution. If any doctor knows any permanent solution please contact me. Clozapine is not for supressing negative voices but is used to calm you and relax you and reduce stress and help you to sleep better. For Visual and auditory hallucination , Respiridone 1 mg is useful daily but Clozapine and Respiridone increase your weight too much. In my case, my weight increased from 45 kg to 67 kg in just three years."

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12 Report
  • Hector
  • Taken for less than 1 month
  • August 28, 2023

For Schizophrenia "I was hearing voices left and right without pause, even planned on committing suicide many times until I took clozapine. It's a miracle drug for schizophrenia. I honestly thought there was no hope for me until I took this medication. The voices completely stopped. It also stopped my visual hallucinations completely. The only side effect it gave me was drowsiness, so I recommend taking it 30 minutes before your sleep time because this medication can seriously make you sleep for 10 hours or more. This drug is a lifesaver and even just 2 days in, I highly recommend it for any schizophrenic looking for hope and getting their life back on track. 10 out of 10, it's the perfect drug."

10 / 10
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  • Kira
  • Taken for 1 to 6 months
  • July 27, 2023

For Schizophrenia "For me, clozapine 300 mg is a lifesaver. Well, it took 3 months for the onset of action of clozapine, so don't lose hope early. Give this drug a full try; I am sure it will benefit you. I have attempted suicide 6-7 times, been admitted to the hospital 6-7 times, visited nimhans twice, and seen more than 10 doctors. I have been diagnosed with schizo, OCD, borderline personality disorder, social anxiety, ruminations, bipolar disorder, and restless leg syndrome for the past 7 and a half years. I have taken more than 20 types of medicine for these diagnoses. Before my illness, I was studying for 12th board and still managed to secure 90% in PCM. I repeat myself, clozapine can take more than 3 months to initiate action. For OCD, I am taking venlafaxine 375 mg."

10 / 10
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2 Report
  • His...
  • March 3, 2020

For Schizophrenia "My brother diagnosed with schizophrenia 2 years ago tried many medications Zyprexa, invega, clopixol, rexulaity nothing worked with him he’s 20 years old now .. he just make the blood test to check if he can take Clozapine medication will see"

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7 Report
  • LastR...
  • Taken for 10 years or more
  • April 26, 2018

For Schizophrenia "After trying many AP's, Clozapine finally settled my Schizoaffective/Schizophenia symptoms. Has a number of side effects, noticably, moderate OCD, temporary stiffness in joints and some initial weight gain. After 10 years, about to swap over to a new drug called Reluxta, which is now on Australian PBS list for AUD$40 (previously AUD$1700). Reluxta is suitable for those coming off Clozapine (slowly), with usually better results & fewer side effects. Some patients may still need to take a reduced Clozapine amount, while taking Reluxta as the main AP."

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • October 17, 2023

For Schizophrenia "Clozapine is almost like a miracle drug for schizophrenia, but it can come with a great cost. I had to stop taking Clozapine because it decreased the amount of white blood cells too much. If I were more unlucky, I could have gotten the common flu and ended up in a hospital (or worse), but my doctor monitored my white blood cell count very actively. Clozapine can cause drooling (scopolamine patches can help), weight gain, and sleepiness (I recommend you take it before going to sleep), but it's also a very effective drug. Because of the downsides, I can't recommend it for other conditions than schizophrenia or psychosis because there are some risks but also a lot of benefits as well."

7 / 10
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  • Shawn
  • Taken for 1 to 6 months
  • July 27, 2023

For Schizophrenia "I'm a 30-year-old schizophrenic. I stopped taking my Latuda 40mg to bring down my sleep hours from 10 to 8 hrs, against my doctor's advice to the contrary, thinking I was well and didn't need it anymore. I underwent a relapse after a month of discontinuing the medication. The relapse damaged my brain, so now I require stronger medication. I have since tried almost all antipsychotics. I searched for a medication that would make me mentally calm. I eventually went on Saphris (Asenapine) 10mg with Latuda 100mg. The night that the Saphris was increased to 10mg, my blood pressure significantly dropped, and I felt akathisia. I took a tranquilizer to help me go to sleep. The blood pressure drop and the akathisia thankfully went away the day after. I performed well on Saphris; I even decreased the Latuda to 40mg. My average sleeping hour was 11-12 hrs a day. My doctor eventually suggested I try clozapine, because I still had minor symptoms--e.g. hearing voices and intrusive thoughts. I was on clozapine for 7 weeks. The target dose was 200mg, but I went up to 150mg. My average sleeping hour increased to 14hrs. (I even once slept for 17hrs.) Clozapine made me very dysfunctional, always tired, fatigued, and unproductive throughout the day. Clozapine is the most sedating, tiring, and fatiguing antipsychotic. I am now switching back to Saphris 12.5mg. Saphris is a bit weaker than clozapine but it is not as tiring. If you remain steadfast and have a healthy diet, the akathisia will hopefully go away. (Press a pillow against your chest lying down when you feel akathisia.) I wish that pharmaceuticals would make strong, mentally-calming-antipsychotics but with an 8hr average sleeping time."

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  • John...
  • Taken for 10 years or more
  • May 18, 2023

"I have Bipolar disorder. Clozapine is an extremely effective mood stabilizer. I was on 100mg for twelve years and had a lot of achievements in my life. The downside was gaining weight and developing type 2 diabetes."

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  • Sabrina
  • Taken for 10 years or more
  • March 22, 2019

Clozaril (clozapine) for Schizophrenia "I had Major Depression with psychotic features and have been on clozaril for 11 blessed years, it works so well. I have long ago lost track of all the antipsychotics and antidepressants I have tried."

10 / 10
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63 Report
  • MATT
  • April 29, 2013

Clozaril (clozapine) for Schizophrenia "I have been taking a small dose 100mg to treat my schizoaffective disorder. I think it helps lower my agitation and helps me to think more clearly. I don't think it helps with my paranoia."

8 / 10
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95 Report
  • Anonymous
  • September 14, 2009

Clozaril (clozapine) for Schizophrenia "Fabulous medicine for schizophrenia"

10 / 10
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101 Report
  • Eliza...
  • Taken for 10 years or more
  • September 24, 2019

For Schizophrenia "I got on clozapine for schizophrenia and have well for years. It gave me a life. I hope the med stays on the market and is always available"

10 / 10
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38 Report
  • lsg
  • July 28, 2015

For Schizophrenia "So far this has worked for my grandson. No more voice or the TV talking to him. He still has a little anxiety. It has been life changing"

10 / 10
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53 Report
  • 2boys...
  • Taken for 1 to 6 months
  • July 17, 2013

For Schizophrenia "One son is schizophrenic and one shizoaffective. After many medicines both have been put on clozapine. Helping a lot with psychotic and social symptoms. Weight gain and lethargy for both."

9 / 10
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61 Report
  • p moore
  • July 10, 2015

For Schizophrenia "So far it has been the best med for my grandson. He no longer hear voices or is delusional. I am so pleased this is working for him. He is almost back to his old self"

10 / 10
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43 Report
  • Lucy
  • September 15, 2018

For Schizophrenia "This is my son 10th day on it .He still in the hospital I see a change in him so far . I will update again when he gets out the hospital."

6 / 10
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22 Report
  • Teren...
  • Taken for 10 years or more
  • April 3, 2021

For Schizophrenia "Powerful drug therapy"

10 / 10
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10 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.