Clomipramine for Depression User Reviews (Page 2)

• clo...
• Taken for less than 1 month
• August 4, 2024

"Been on it for 10 days today along with mitrazipine 30 mg, hoping this will work for me soon as I suffer from depression and anxiety, the only side effect I got was reduced appetite and anxiety, will it get better anyone please need some advice, support, thanks too early to rate it now, hoping it will work soon."

• Anonymous
• Taken for 5 to 10 years
• June 10, 2019

"OMG, everybody on these reviews is so keen on telling people to try clomipramine. Are you kidding me? If you are sensitive to meds, this stuff is the worst. It is much, much more powerful than other options. It can make you extremely unstable and unwell. There’s a reason newer treatments were developed, they are much more selective, and this is the very, very, very last resort after literally trying everything. I was put on this during a depressive episode when I needed different bipolar options, and it turned me into something scary, plus caused constant nervousness. I recommend more gentle mood-stabilizing or antidepressant options over this stuff. I feel it completely harmed me after being put on it at a high dose of up to 150 mg for a long time by a reckless hospital that just made things worse. I was in a vicious cycle of being on this terrible med. If you need to try it, make sure you take the lowest dose. Powerful, powerful stuff."

• moa...
• Taken for 1 to 2 years
• February 7, 2018

"It's the best medication I've ever had for MDD and GAD. It initially came with sedation, tremor, constipation, urinary retention, body pain, and so on, but after being on it for a year (and thanks to some acupuncture), all the side effects are gone. If not for the side effects, I'd recommend it to everyone! Only current downside is it only comes in 25 mg tablets, apparently, and I take 150 mg, so that's 6 tablets, and that runs out quickly."

• Wel...
• Taken for 10 years or more
• January 13, 2019

"Help, clomipramine has been discontinued! Can't get it in the UK anymore. I have been on it on and off for over 30 years. Having an episode of depression now which started in September 2018, now January 2019, and now being tapered to sertraline. Scared!!"

• Cer...
• Taken for 6 months to 1 year
• September 17, 2018

"This did seem to give me a bit of energy, but the side effects were not good. At the highest dose, I was shaking so bad I couldn't write, I got dizzy every time I stood up, had electric shock feelings in my head, and terrible twitching all evening and night. Luckily, all the side effects stopped when I came off of it, but this was definitely not the right drug for me."

• bas...
• Taken for less than 1 month
• December 7, 2018

"Just started on it a few days ago, but I have noticed that my racing thoughts have stopped. So far, I don't have any side effects, but to keep calm, I have been using natural supplements, and it seems to be working for me. Good luck to all."

• Anonymous
• Taken for 10 years or more
• March 7, 2018

"Since finally demanding to wean off this drug, my life has improved dramatically. My docs always said I could not afford to stop this med, although I had 7 hospitalizations and 3 suicide attempts. After 25 years and 30 grand out of pocket, I started the weaning process from 200 mg to now 25 mg. Cerebral blood flow was inhibited, as well as blood flow to all other organs. Most noticeably, I now have the return of erections. Constipation, which took me to the ER for manual extraction, is now gone. Urinary inhibition, sometimes up to 1 to 2 hours, is gone. This med worsened my depression in many ways and cost me 20 years of a good life, as well as the loss of career, family, self-confidence, dignity, respect, and hundreds of thousands of dollars in income, medical bills, and more. Hopefully, this may help others who are on this drug or are considering it for treatment, as well as docs who prescribe, especially long term. That’s all. Good luck to all!"

• wen...
• Taken for 6 months to 1 year
• October 7, 2024

"I have been depressed nearly 33 years. I've tried 24 different medications, Spravato, and TMS. My psychiatrist suggested starting this. I'll be honest, I did not have high hopes about it at all, but after one week, I started feeling better. I've been on it now for approximately 6 months, and I've got my motivation back, the dark cloud that followed me is gone. I do have some side effects such as constipation and talking in my sleep, but I can deal with those. I know everyone is different, but my hope is that if it doesn't work, to not give up. There's a medication out there for you, you just have to keep looking."

• Teo...
• Taken for 1 to 2 years
• August 11, 2022

"This drug is very effective for depression and generalized anxiety disorder but has ruined my life. I took it for more than two years, at first, the only side effect was delayed ejaculation. After two years of use, I started experiencing low libido and severe erectile dysfunction. I stopped taking it, and 10 months later, I’m still completely impotent, like a 90-year-old man, it seems to be permanent."

• Bir...
• Taken for less than 1 month
• December 4, 2018

"I have been taking this medication for a little over two weeks. I started off at 50 mg, and then after 14 days, I increased to 100 mg. I thought I would start to feel better, but I have been so depressed. I have still been struggling with the OCD. I also have bipolar 2. I am also wondering if I am feeling like this from coming off of Lexapro. I am just overwhelmed. I really want this medicine to work. Maybe it will just take more time..."

• Ufa...
• Taken for 6 months to 1 year
• May 4, 2020

"I've been about 8 months on clomipramine. It gives me obsessive thoughts that weren't there before I started this drug (I was on it for depression). I shouldn't have taken it. But it was a must since my psychiatrist prescribed it."

• Ken...
• Taken for less than 1 month
• December 17, 2020

"Only took 25 mgs of clomipramine, and the effects were horrendous: shaking, restlessness, all-over body burning, pins and needles, anxiety, nausea, insomnia. It was so bad I ended up in A&E. I'm glad I only took 3 doses."

• Jak...
• Taken for 5 to 10 years
• July 4, 2019

"Terrible medication that is way too powerful for anybody sensitive to medications. Caused a lot of nervousness, mania, and mixed states for me when used in a depressive episode when struggling with OCD and needed safe mood stabilizing meds, as well as safer OCD options like Luvox at a low dose. Stick with safer options, this stuff is terrible, it is very powerful."

• ImA...
• Taken for less than 1 month
• May 20, 2020

"Strong, nasty drug! Given clomipramine for anxiety, obsessive thoughts/ruminations, and depression. SSRIs are not much help, and Effexor helped for a while and then stopped. Pristiq didn’t help. So we tried clomipramine, an older drug. I only took 25 mg for 4 days before calling it quits! Very strong sedating effects but didn't really put me to sleep the first 2 days. Then the next three days, wow! This put me on my back the entire day! I couldn’t function and do anything. I just wanted to lay down because I was so exhausted but couldn’t sleep!!! That’s disastrous! I hated that feeling! It also gave me restless legs, which further worsened my ability to stay asleep! Now I’m gonna try buspar since I’m so sensitive to medication."

• Mic...
• Taken for less than 1 month
• August 23, 2020

"I'm just starting this medication. I've been off meds for the past 6 years because I kept reading horror stories about what antidepressants do to you, so I went down the natural route, which unfortunately didn't work. My anxiety and depression have gradually gotten worse, so I'm going to give this a try. But I'm so worried that it might make me worse, as I've read a few negative reviews."

• Anonymous
• Taken for 1 to 6 months
• March 27, 2018

Clomipramine "I was prescribed Anafranil for depression after having a stillborn baby. It was given to me intravenously, and during one treatment, I had a fit which caused my shoulder to dislocate. Following this, I was prescribed a smaller dose in tablet form, which made no difference to my depression. Not long after, I had another fit which again resulted in a dislocated shoulder! Following this second incident, I stopped taking the drug. All in all, my shoulder dislocated 14 times due to damage caused by this drug until it was finally operated on, but I never gained full use of the arm and still experience pain at times. I felt my personality had changed, and I was unable to function and finally got better by talking to a very understanding psychologist. I still have episodes of depression but have learned to cope with them with determination and the help of relatives and friends. Needless to say, I was not impressed with Anafranil in my case."

• JW ...
• September 3, 2014

Clomipramine "This medicine has minimal side effects. It makes me less sad or reduces obsessive worry. It lowers my anxiety. It also helps with digestion regularity."

• Rob...
• Taken for 10 years or more
• September 11, 2016

"Tried every AD pill, and this is the only one that's worked for me."

• Des...
• October 18, 2024

"Incredibly effective for depression. I really like this medicine. I'm glad I know it exists."

• Des...
• October 19, 2024

"I love this medicine. It's noticeably effective. I'm glad I came across this drug."

• Anonymous
• Taken for 10 years or more
• March 15, 2022

"I've been on this drug for 30 years, it was like coming out of a dark tunnel. I've tried to change them, but others don't work as well for me."

• Ugh...
• Taken for 1 to 6 months
• March 28, 2022

"It worked great for me until I got up to 100 mgs and got urinary retention and had to get a catheter put in."

• New...
• July 17, 2017

"I would like to know everyone's experiences on this drug, please. Does it cause insomnia?"

• Eul...
• Taken for 1 to 6 months
• December 26, 2019

"This medication doesn't work for me. I've been on it for two months on 75 mg clomipramine. Now my psychiatrist has made it 100 mg. He said to give it a try for two months."

• Ale...
• Taken for 6 months to 1 year
• March 25, 2019

"Clomipramine causes mania, psychedelic effects, hallucinations that won't go away. I think this is too strong for bipolar people. Dangerous."